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4WZJ
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BU of 4wzj by Molmil
Spliceosomal U4 snRNP core domain
分子名称: Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein G, ...
著者Leung, A.K.W, Nagai, K, Li, J.
登録日2014-11-19
公開日2015-01-14
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structure of the spliceosomal U4 snRNP core domain and its implication for snRNP biogenesis.
Nature, 473, 2011
7ABH
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BU of 7abh by Molmil
Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion)
分子名称: Cell division cycle 5-like protein, DNA/RNA-binding protein KIN17, MINX M3 pre-mRNA, ...
著者Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R.
登録日2020-09-07
公開日2020-12-09
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
7DCO
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BU of 7dco by Molmil
Cryo-EM structure of the activated spliceosome (Bact complex) at an atomic resolution of 2.5 angstrom
分子名称: BJ4_G0014900.mRNA.1.CDS.1, BJ4_G0027490.mRNA.1.CDS.1, BJ4_G0037700.mRNA.1.CDS.1, ...
著者Bai, R, Wan, R, Yan, C, Qi, J, Zhang, P, Lei, J, Shi, Y.
登録日2020-10-26
公開日2021-03-17
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Mechanism of spliceosome remodeling by the ATPase/helicase Prp2 and its coactivator Spp2.
Science, 371, 2021
8H6K
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BU of 8h6k by Molmil
Cryo-EM structure of human exon-defined spliceosome in the mature B state.
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
著者Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y.
登録日2022-10-18
公開日2024-05-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural insights into human exon-defined spliceosome prior to activation.
Cell Res., 34, 2024
8H6L
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BU of 8h6l by Molmil
Cryo-EM structure of human exon-defined spliceosome in the early B state.
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
著者Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y.
登録日2022-10-18
公開日2024-05-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural insights into human exon-defined spliceosome prior to activation.
Cell Res., 34, 2024
8H6J
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BU of 8h6j by Molmil
Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state.
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
著者Zhang, W, Zhan, X, Zhang, X, Lei, J, Yan, C, Shi, Y.
登録日2022-10-18
公開日2024-05-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Structural insights into human exon-defined spliceosome prior to activation.
Cell Res., 34, 2024
8H6E
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BU of 8h6e by Molmil
Cryo-EM structure of human exon-defined spliceosome in the late pre-B state.
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
著者Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y.
登録日2022-10-17
公開日2024-05-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insights into human exon-defined spliceosome prior to activation.
Cell Res., 34, 2024
2FHO
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BU of 2fho by Molmil
NMR solution structure of the human spliceosomal protein complex p14-SF3b155
分子名称: spliceosomal protein SF3b155, spliceosomal protein p14
著者Kuwasako, K, Dohmae, N, Inoue, M, Shirouzu, M, Guntert, P, Seraphin, B, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-26
公開日2006-12-26
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献NMR solution structure of the human spliceosomal protein complex p14-SF3b155
To be Published
4ZB4
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BU of 4zb4 by Molmil
Spliceosome component
分子名称: Pre-mRNA-processing factor 19
著者Rocha de Moura, T, Pena, P.
登録日2015-04-14
公開日2016-09-14
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Spliceosome component
To Be Published
5YLZ
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BU of 5ylz by Molmil
Cryo-EM Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae at 3.6 angstrom
分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
著者Wan, R, Yan, C, Bai, R, Lei, J, Shi, Y.
登録日2017-10-20
公開日2018-07-18
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae
Cell, 171, 2017
5Y88
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BU of 5y88 by Molmil
Cryo-EM structure of the intron-lariat spliceosome ready for disassembly from S.cerevisiae at 3.5 angstrom
分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Intron lariat, ...
著者Wan, R, Yan, C, Bai, R, Lei, J, Shi, Y.
登録日2017-08-20
公開日2018-08-01
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Structure of an Intron Lariat Spliceosome from Saccharomyces cerevisiae
Cell(Cambridge,Mass.), 171, 2017
8Y6O
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BU of 8y6o by Molmil
Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U11 and tri-snRNP part
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Centrosomal AT-AC splicing factor, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Bai, R, Yuan, M, Zhang, P, Luo, T, Shi, Y, Wan, R.
登録日2024-02-02
公開日2024-03-20
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome.
Science, 383, 2024
8Y7E
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BU of 8y7e by Molmil
Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U12 snRNP part
分子名称: PHD finger-like domain-containing protein 5A, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, ...
著者Bai, R, Yuan, M, Zhang, P, Luo, T, Shi, Y, Wan, R.
登録日2024-02-04
公開日2024-03-13
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.66 Å)
主引用文献Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome.
Science, 383, 2024
7W5B
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BU of 7w5b by Molmil
The cryo-EM structure of human C* complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ...
著者Zhan, X, Lu, Y, Shi, Y.
登録日2021-11-29
公開日2022-06-22
最終更新日2022-08-17
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Mechanism of exon ligation by human spliceosome.
Mol.Cell, 82, 2022
7W5A
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BU of 7w5a by Molmil
The cryo-EM structure of human pre-C*-II complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ...
著者Zhan, X, Lu, Y, Shi, Y.
登録日2021-11-29
公開日2022-06-22
最終更新日2022-08-17
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Mechanism of exon ligation by human spliceosome.
Mol.Cell, 82, 2022
7W59
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BU of 7w59 by Molmil
The cryo-EM structure of human pre-C*-I complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ...
著者Zhan, X, Lu, Y, Shi, Y.
登録日2021-11-29
公開日2022-06-22
最終更新日2022-08-17
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Mechanism of exon ligation by human spliceosome.
Mol.Cell, 82, 2022
5MQ0
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BU of 5mq0 by Molmil
Structure of a spliceosome remodeled for exon ligation
分子名称: 3'-EXON OF UBC4 PRE-MRNA, BOUND BY PRP22 HELICASE, 5'-EXON OF UBC4 PRE-MRNA, ...
著者Fica, S.M, Oubridge, C, Galej, W.P, Wilkinson, M.E, Newman, A.J, Bai, X.-C, Nagai, K.
登録日2016-12-19
公開日2017-01-18
最終更新日2020-10-07
実験手法ELECTRON MICROSCOPY (4.17 Å)
主引用文献Structure of a spliceosome remodelled for exon ligation.
Nature, 542, 2017
5MPS
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BU of 5mps by Molmil
Structure of a spliceosome remodeled for exon ligation
分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
著者Fica, S.M, Oubridge, C, Galej, W.P, Wilkinson, M.E, Newman, A.J, Bai, X.-C, Nagai, K.
登録日2016-12-18
公開日2017-01-18
最終更新日2020-10-07
実験手法ELECTRON MICROSCOPY (3.85 Å)
主引用文献Structure of a spliceosome remodelled for exon ligation.
Nature, 542, 2017
5O9Z
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BU of 5o9z by Molmil
Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Homo sapiens RNA, U6 small nuclear 1 (RNU6-1), ...
著者Bertram, K, Kastner, B.
登録日2017-06-20
公開日2017-08-16
最終更新日2018-10-24
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.
Cell, 170, 2017
5WSG
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BU of 5wsg by Molmil
Cryo-EM structure of the Catalytic Step II spliceosome (C* complex) at 4.0 angstrom resolution
分子名称: 3'-exon-intron, 3'-intron-lariat, 5'-exon, ...
著者Yan, C, Wan, R, Bai, R, Huang, G, Shi, Y.
登録日2016-12-07
公開日2017-01-25
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structure of a yeast step II catalytically activated spliceosome
Science, 355, 2017
3CW1
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BU of 3cw1 by Molmil
Crystal Structure of Human Spliceosomal U1 snRNP
分子名称: Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein G, ...
著者Pomeranz Krummel, D.A, Oubridge, C, Leung, A.K, Li, J, Nagai, K.
登録日2008-04-21
公開日2009-03-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (5.493 Å)
主引用文献Crystal structure of human spliceosomal U1 snRNP at 5.5 A resolution.
Nature, 458, 2009
6AHD
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BU of 6ahd by Molmil
The Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolution
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Brr2, U5 small nuclear ribonucleoprotein 200 kDa helicase, ...
著者Zhan, X, Yan, C, Zhang, X, Shi, Y.
登録日2018-08-17
公開日2018-11-14
最終更新日2021-06-30
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structures of the human pre-catalytic spliceosome and its precursor spliceosome.
Cell Res., 28, 2018
6BK8
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BU of 6bk8 by Molmil
S. cerevisiae spliceosomal post-catalytic P complex
分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Lea1, ...
著者Liu, S, Li, X, Zhou, Z.H, Zhao, R.
登録日2017-11-07
公開日2018-02-21
最終更新日2020-10-14
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure of the yeast spliceosomal postcatalytic P complex.
Science, 358, 2017
6AH0
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BU of 6ah0 by Molmil
The Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
著者Zhan, X, Yan, C, Zhang, X, Shi, Y.
登録日2018-08-15
公開日2018-11-14
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (5.7 Å)
主引用文献Structures of the human pre-catalytic spliceosome and its precursor spliceosome.
Cell Res., 28, 2018
5ZWM
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BU of 5zwm by Molmil
Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.4~4.6 angstrom (tri-snRNP and U2 snRNP Part)
分子名称: 13 kDa ribonucleoprotein-associated protein, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, Cold sensitive U2 snRNA suppressor 1, ...
著者Bai, R, Wan, R, Yan, C, Lei, J, Shi, Y.
登録日2018-05-16
公開日2018-08-29
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
Science, 360, 2018

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