8C5V
 
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7QJ9
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7QJ6
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1L5E
 | | The domain-swapped dimer of CV-N in solution | | 分子名称: | Cyanovirin-N | | 著者 | Barrientos, L.G, Louis, J.M, Botos, I, Mori, T, Han, Z, O'Keefe, B.R, Boyd, M.R, Wlodawer, A, Gronenborn, A.M. | | 登録日 | 2002-03-06 | | 公開日 | 2002-06-05 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The domain-swapped dimer of cyanovirin-N is in a metastable folded state: reconciliation of X-ray and NMR structures.
Structure, 10, 2002
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1DN9
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7YZY
 | | pMMO structure from native membranes by cryoET and STA | | 分子名称: | Methane monooxygenase subunit C2, Particulate methane monooxygenase alpha subunit, Particulate methane monooxygenase beta subunit | | 著者 | Zhu, Y, Ni, T, Zhang, P. | | 登録日 | 2022-02-21 | | 公開日 | 2022-08-10 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Structure and activity of particulate methane monooxygenase arrays in methanotrophs.
Nat Commun, 13, 2022
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3LXR
 | | Shigella IpgB2 in complex with human RhoA and GDP (complex C) | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, IpgB2, SULFATE ION, ... | | 著者 | Klink, B.U, Barden, S, Heidler, T.V, Borchers, C, Ladwein, M, Stradal, T.E.B, Rottner, K, Heinz, D.W. | | 登録日 | 2010-02-25 | | 公開日 | 2010-03-31 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Structure of Shigella IPGB2 in complex with human RhoA: Implications for the mechanism of bacterial GEF-mimicry
J.Biol.Chem., 285, 2010
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3LWN
 | | Shigella IpgB2 in complex with human RhoA, GDP and Mg2+ (complex B) | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, IpgB2, MAGNESIUM ION, ... | | 著者 | Klink, B.U, Barden, S, Heidler, T.V, Borchers, C, Ladwein, M, Stradal, T.E.B, Rottner, K, Heinz, D.W. | | 登録日 | 2010-02-24 | | 公開日 | 2010-03-31 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Structure of Shigella IPGB2 in complex with human RhoA: Implications for the mechanism of bacterial GEF-mimicry
J.Biol.Chem., 285, 2010
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2LYH
 | | Structure of Faap24 residues 141-215 | | 分子名称: | Fanconi anemia-associated protein of 24 kDa | | 著者 | Wienk, H, Slootweg, J, Kaptein, R, Boelens, R, Folkers, G.E. | | 登録日 | 2012-09-18 | | 公開日 | 2013-05-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Fanconi anemia associated protein FAAP24 uses two substrate specific binding surfaces for DNA recognition.
Nucleic Acids Res., 41, 2013
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7YUY
 | | Structure of a mutated membrane-bound glycosyltransferase | | 分子名称: | (11R,14S)-17-amino-14-hydroxy-8,14-dioxo-9,13,15-trioxa-14lambda~5~-phosphaheptadecan-11-yl decanoate, 1,3-beta-glucan synthase component FKS1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Hu, X.L, Yang, P, Zhang, M, Liu, X.T, Yu, H.J. | | 登録日 | 2022-08-18 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-04-19 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural and mechanistic insights into fungal beta-1,3-glucan synthase FKS1.
Nature, 616, 2023
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7ZAU
 | | Fascin-1 in complex with Nb 3E11 | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Fascin, ... | | 著者 | Burgess, S.G, Bayliss, R. | | 登録日 | 2022-03-22 | | 公開日 | 2023-09-27 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A nanobody inhibitor of Fascin-1 actin-bundling activity and filopodia formation.
Open Biology, 14, 2024
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2N1Q
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6ANU
 | | Cryo-EM structure of F-actin complexed with the beta-III-spectrin actin-binding domain | | 分子名称: | Actin, cytoplasmic 1, Spectrin beta chain, ... | | 著者 | Wang, F, Orlova, A, Avery, A.W, Hays, T.S, Egelman, E.H. | | 登録日 | 2017-08-14 | | 公開日 | 2017-11-22 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (7 Å) | | 主引用文献 | Structural basis for high-affinity actin binding revealed by a beta-III-spectrin SCA5 missense mutation.
Nat Commun, 8, 2017
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309D
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3MOY
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8COG
 | | Human arginylated beta-actin | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | | 著者 | Pinto, C.S, Bakker, S.E, Suchenko, A, Hussain, H, Hatano, T, Sampath, K, Chinthalapudi, K, Mishima, M, Balasubramanian, M. | | 登録日 | 2023-02-28 | | 公開日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.499 Å) | | 主引用文献 | Structure and physiological investigation of human arginylated beta-actin
To Be Published
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7ZTC
 | | Non-muscle F-actin decorated with non-muscle tropomyosin 1.6 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Non-muscle tropomyosin 1.6, actin, ... | | 著者 | Selvaraj, M, Kokate, S, Kogan, K, Kotila, T, Kremneva, E, Lappalainen, P, Huiskonen, J.T. | | 登録日 | 2022-05-09 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-02-15 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural basis underlying specific biochemical activities of non-muscle tropomyosin isoforms.
Cell Rep, 42, 2023
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7ZTD
 | | Non-muscle F-actin decorated with non-muscle tropomyosin 3.2 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Non-muscle tropomyosin 3.2, actin, ... | | 著者 | Selvaraj, M, Kokate, S, Kogan, K, Kotila, T, Kremneva, E, Lappalainen, P, Huiskonen, J.T. | | 登録日 | 2022-05-09 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-02-15 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Structural basis underlying specific biochemical activities of non-muscle tropomyosin isoforms.
Cell Rep, 42, 2023
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3OB4
 | | MBP-fusion protein of the major peanut allergen Ara h 2 | | 分子名称: | CHLORIDE ION, Maltose ABC transporter periplasmic protein,Arah 2, SULFATE ION, ... | | 著者 | Mueller, G.A, Gosavi, R.A, Moon, A.F, London, R.E, Pedersen, L.C. | | 登録日 | 2010-08-06 | | 公開日 | 2011-02-02 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.706 Å) | | 主引用文献 | Ara h 2: crystal structure and IgE binding distinguish two subpopulations of peanut allergic patients by epitope diversity.
Allergy, 66, 2011
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3MQM
 | | Crystal Structure of the Bromodomain of human ASH1L | | 分子名称: | Probable histone-lysine N-methyltransferase ASH1L | | 著者 | Filippakopoulos, P, Picaud, S, Keates, T, Felletar, I, Vollmar, M, Chaikuad, A, Krojer, T, Canning, P, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2010-04-28 | | 公開日 | 2010-05-19 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | | 主引用文献 | Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
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3NCC
 | | A human Prolactin receptor antagonist in complex with the mutant extracellular domain H188A of the human prolactin receptor | | 分子名称: | CARBONATE ION, CHLORIDE ION, Prolactin, ... | | 著者 | Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E. | | 登録日 | 2010-06-04 | | 公開日 | 2010-09-29 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation.
J.Biol.Chem., 285, 2010
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3NDN
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8DNH
 | | Cryo-EM structure of nonmuscle beta-actin | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | | 著者 | Arora, A.S, Huang, H.L, Heissler, S.M, Chinthalapudi, K. | | 登録日 | 2022-07-11 | | 公開日 | 2023-04-12 | | 実験手法 | ELECTRON MICROSCOPY (2.99 Å) | | 主引用文献 | Structural insights into actin isoforms.
Elife, 12, 2023
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3MB3
 | | Crystal Structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) | | 分子名称: | 1-methylpyrrolidin-2-one, PH-interacting protein | | 著者 | Filippakopoulos, P, Picaud, S, Keates, T, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2010-03-25 | | 公開日 | 2010-04-14 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
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3MXF
 | | Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor JQ1 | | 分子名称: | (6S)-6-(2-tert-butoxy-2-oxoethyl)-4-(4-chlorophenyl)-2,3,9-trimethyl-6,7-dihydrothieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-10-ium, 1,2-ETHANEDIOL, Bromodomain-containing protein 4, ... | | 著者 | Filippakopoulos, P, Picaud, S, Qi, J, Keates, T, Felletar, I, Fedorov, O, Muniz, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Bradner, J.E, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2010-05-07 | | 公開日 | 2010-10-06 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Selective inhibition of BET bromodomains.
Nature, 468, 2010
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