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4GMJ
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Structure of human NOT1 MIF4G domain co-crystallized with CAF1
分子名称: CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 7, CHLORIDE ION, ...
著者Petit, P, Weichenrieder, O, Wohlbold, L, Izaurralde, E.
登録日2012-08-16
公開日2012-10-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex
Nucleic Acids Res., 40, 2012
6KWB
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BU of 6kwb by Molmil
AtDAO1(dioxygenase for auxin oxidation 1 from Arabidopsis thaliana) - 2-oxoglutarate binray complex
分子名称: 2-OXOGLUTARIC ACID, 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein, MAGNESIUM ION
著者Rhee, S, Jin, S, Lee, H.
登録日2019-09-06
公開日2020-11-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5183928 Å)
主引用文献Crystal structure of the indole-3-acetic acid-catabolizing enzyme DAO1 from Arabidopsis thaliana.
J.Struct.Biol., 212, 2020
6L29
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BU of 6l29 by Molmil
The structure of the MazF-mt1 mutant
分子名称: mRNA interferase
著者Xie, W, Chen, R, Zhou, J.
登録日2019-10-02
公開日2020-08-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3000052 Å)
主引用文献Conserved Conformational Changes in the Regulation ofMycobacterium tuberculosisMazEF-mt1.
Acs Infect Dis., 6, 2020
6L5B
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BU of 6l5b by Molmil
The structure of the UdgX mutant H109E at a post-excision state
分子名称: IRON/SULFUR CLUSTER, Uracil DNA glycosylase superfamily protein
著者Xie, W, Tu, J, Zeng, H.
登録日2019-10-22
公開日2020-10-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.00004983 Å)
主引用文献Structural insights into an MsmUdgX mutant capable of both crosslinking and uracil excision capability.
DNA Repair (Amst), 97, 2021
2CH5
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BU of 2ch5 by Molmil
Crystal structure of human N-acetylglucosamine kinase in complex with N-acetylglucosamine
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者Weihofen, W.A, Berger, M, Chen, H, Saenger, W, Hinderlich, S.
登録日2006-03-13
公開日2006-09-18
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of Human N-Acetylglucosamine Kinase in Two Complexes with N-Acetylglucosamine and with Adp/Glucose: Insights Into Substrate Specificity and Regulation.
J.Mol.Biol., 364, 2006
7PQH
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BU of 7pqh by Molmil
Cryo-EM structure of Saccharomyces cerevisiae TOROID (TORC1 Organized in Inhibited Domains).
分子名称: Serine/threonine-protein kinase TOR2, Target of rapamycin complex 1 subunit KOG1,Target of rapamycin complex 1 subunit Kog1, Target of rapamycin complex subunit LST8
著者Felix, J, Prouteau, M, Bourgoint, C, Bonadei, L, Desfosses, A, Gabus, C, Sadian, Y, Savvides, S.N, Gutsche, I, Loewith, R.
登録日2021-09-17
公開日2023-01-18
最終更新日2023-03-29
実験手法ELECTRON MICROSCOPY (3.87 Å)
主引用文献EGOC inhibits TOROID polymerization by structurally activating TORC1.
Nat.Struct.Mol.Biol., 30, 2023
4GVM
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BU of 4gvm by Molmil
HIV-1 Integrase Catalytic Core Domain A128T Mutant Complexed with Allosteric Inhibitor
分子名称: (2S)-[6-bromo-4-(4-chlorophenyl)-2-methylquinolin-3-yl](tert-butoxy)ethanoic acid, ARSENIC, Gag-Pol polyprotein
著者Feng, L, Kvaratskhelia, M.
登録日2012-08-30
公開日2013-05-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献The A128T Resistance Mutation Reveals Aberrant Protein Multimerization as the Primary Mechanism of Action of Allosteric HIV-1 Integrase Inhibitors.
J.Biol.Chem., 288, 2013
3F62
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Crystal Structure of Human IL-18 in complex with Ectromelia virus IL-18 Binding Protein
分子名称: Interleukin 18 binding protein, Interleukin-18
著者Krumm, B.E, Li, Y, Deng, J.
登録日2008-11-05
公開日2009-01-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for antagonism of human interleukin 18 by poxvirus interleukin 18-binding protein.
Proc.Natl.Acad.Sci.USA, 105, 2008
3KM6
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BU of 3km6 by Molmil
Crystal Structure of the Human GST Pi C47S/Y108V Double Mutant in Complex with the Ethacrynic Acid-Glutathione Conjugate
分子名称: CALCIUM ION, ETHACRYNIC ACID, GLUTATHIONE, ...
著者Parker, L.J.
登録日2009-11-10
公開日2010-03-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Diuretic drug binding to human glutathione transferase P1-1: potential role of Cys-101 revealed in the double mutant C47S/Y108V.
J.Mol.Recognit., 24
2CH6
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BU of 2ch6 by Molmil
Crystal structure of human N-acetylglucosamine kinase in complex with ADP and glucose
分子名称: ADENOSINE-5'-DIPHOSPHATE, N-ACETYL-D-GLUCOSAMINE KINASE, alpha-D-glucopyranose
著者Weihofen, W.A, Berger, M, Chen, H, Saenger, W, Hinderlich, S.
登録日2006-03-13
公開日2006-09-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Structures of Human N-Acetylglucosamine Kinase in Two Complexes with N-Acetylglucosamine and with Adp/Glucose: Insights Into Substrate Specificity and Regulation.
J.Mol.Biol., 364, 2006
3EE9
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BU of 3ee9 by Molmil
Structure of NS1 effector domain
分子名称: Non-structural protein 1, SULFATE ION
著者Xia, S, Monzingo, A.F, Robertus, J.D.
登録日2008-09-04
公開日2009-01-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Structure of NS1A effector domain from the influenza A/Udorn/72 virus.
Acta Crystallogr.,Sect.D, 65, 2009
5CHT
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BU of 5cht by Molmil
Crystal structure of USP18
分子名称: Ubl carboxyl-terminal hydrolase 18, ZINC ION
著者Fritz, G, Basters, A.
登録日2015-07-10
公開日2016-06-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of the specificity of USP18 toward ISG15.
Nat. Struct. Mol. Biol., 24, 2017
3EE8
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BU of 3ee8 by Molmil
Structure of NS1 effector domain
分子名称: Non-structural protein 1
著者Xia, S, Monzingo, A.F, Robertus, J.D.
登録日2008-09-04
公開日2009-01-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of NS1A effector domain from the influenza A/Udorn/72 virus.
Acta Crystallogr.,Sect.D, 65, 2009
5YZW
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BU of 5yzw by Molmil
Crystal structure of p204 HINb domain
分子名称: Ifi204
著者Jin, T.
登録日2017-12-15
公開日2018-12-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Structural mechanism of DNA recognition by the p204 HIN domain.
Nucleic Acids Res., 2021
2DFS
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BU of 2dfs by Molmil
3-D structure of Myosin-V inhibited state
分子名称: Calmodulin, Myosin-5A
著者Liu, J, Taylor, D.W, Krementsova, E.B, Trybus, K.M, Taylor, K.A.
登録日2006-03-03
公開日2006-04-25
最終更新日2024-03-13
実験手法ELECTRON CRYSTALLOGRAPHY (24 Å)
主引用文献Three-dimensional structure of the myosin V inhibited state by cryoelectron tomography
Nature, 442, 2006
3PKV
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BU of 3pkv by Molmil
Crystal Structure of Toxoflavin Lyase (TflA)
分子名称: Toxoflavin lyase (TflA)
著者Fenwick, M.K, Philmus, B, Begley, T.P, Ealick, S.E.
登録日2010-11-12
公開日2011-01-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Toxoflavin lyase requires a novel 1-his-2-carboxylate facial triad .
Biochemistry, 50, 2011
5KDU
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BU of 5kdu by Molmil
ZmpB metallopeptidase in complex with a2,6-Sialyl T-antigen
分子名称: 1,2-ETHANEDIOL, F5/8 type C domain protein, SERINE, ...
著者Noach, I, Ficko-Blean, E, Stuart, C, Boraston, A.B.
登録日2016-06-08
公開日2017-01-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Recognition of protein-linked glycans as a determinant of peptidase activity.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5KAH
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BU of 5kah by Molmil
Crystal structure of a dioxygenase in the Crotonase superfamily in P21, V425T mutant
分子名称: (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL (3R)-4-({3-[(2-{[(3,5-DIHYDROXYPHENYL)ACETYL]AMINO}ETHYL)AMINO]-3-OXOPROPYL}AMINO)-3-HYDROXY-2,2-DIMETHYL-4-OXOBUTYL DIHYDROGEN DIPHOSPHATE
著者Li, K, Fielding, E.N, Condurso, H.L, Bruner, S.D.
登録日2016-06-01
公開日2017-06-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.779 Å)
主引用文献Probing the structural basis of oxygen binding in a cofactor-independent dioxygenase.
Acta Crystallogr D Struct Biol, 73, 2017
5KAG
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BU of 5kag by Molmil
Crystal structure of a dioxygenase in the Crotonase superfamily in P21
分子名称: (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase, OXYGEN MOLECULE, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL (3R)-4-({3-[(2-{[(3,5-DIHYDROXYPHENYL)ACETYL]AMINO}ETHYL)AMINO]-3-OXOPROPYL}AMINO)-3-HYDROXY-2,2-DIMETHYL-4-OXOBUTYL DIHYDROGEN DIPHOSPHATE
著者Li, K, Fielding, E.N, Condurso, H.L, Bruner, S.D.
登録日2016-06-01
公開日2017-06-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.456 Å)
主引用文献Probing the structural basis of oxygen binding in a cofactor-independent dioxygenase.
Acta Crystallogr D Struct Biol, 73, 2017
5KDS
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BU of 5kds by Molmil
ZmpB metallopeptidase in complex with an O-glycopeptide (a2,6-sialylated core-3 pentapeptide).
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[N-acetyl-alpha-neuraminic acid-(2-6)]2-acetamido-2-deoxy-alpha-D-galactopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Noach, I, Ficko-Blean, E, Stuart, C, Boraston, A.B.
登録日2016-06-08
公開日2017-01-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Recognition of protein-linked glycans as a determinant of peptidase activity.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6O84
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BU of 6o84 by Molmil
Cryo-EM structure of OTOP3 from xenopus tropicalis
分子名称: LOC100127796 protein,LOC100127796 protein,OTOP3,LOC100127796 protein,LOC100127796 protein
著者Chen, Q.F, Bai, X.C, Jiang, Y.X.
登録日2019-03-08
公開日2019-04-24
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.92 Å)
主引用文献Structural and functional characterization of an otopetrin family proton channel.
Elife, 8, 2019
5KOL
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Crystal structure of the competence-damaged protein (CinA) superfamily protein ECK1530/EC0983 from Escherichia coli
分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
著者Stogios, P.J, Wawrak, Z, Evdokimova, E, Di Leo, R, Grimshaw, S, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2016-06-30
公開日2016-07-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献To be published
To Be Published
2BE6
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BU of 2be6 by Molmil
2.0 A crystal structure of the CaV1.2 IQ domain-Ca/CaM complex
分子名称: CALCIUM ION, Calmodulin 2, NICKEL (II) ION, ...
著者Van Petegem, F, Chatelain, F.C, Minor Jr, D.L.
登録日2005-10-23
公開日2005-11-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Insights into voltage-gated calcium channel regulation from the structure of the Ca(V)1.2 IQ domain-Ca(2+)/calmodulin complex
Nat.Struct.Mol.Biol., 12, 2005
7KTS
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BU of 7kts by Molmil
Negative stain EM structure of the human SAGA coactivator complex (TRRAP, core, splicing module)
分子名称: Ataxin-7, Isoform 3 of Transcription factor SPT20 homolog, STAGA complex 65 subunit gamma, ...
著者Herbst, D.A, Esbin, M.N, Nogales, E.
登録日2020-11-24
公開日2021-11-10
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (19.09 Å)
主引用文献Structure of the human SAGA coactivator complex.
Nat.Struct.Mol.Biol., 28, 2021
2I5B
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The crystal structure of an ADP complex of Bacillus subtilis pyridoxal kinase provides evidence for the parralel emergence of enzyme activity during evolution
分子名称: ADENOSINE-5'-DIPHOSPHATE, Phosphomethylpyrimidine kinase
著者Newman, J.A, Das, S.K, Sedelnikova, S.E, Rice, D.W.
登録日2006-08-24
公開日2006-09-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Crystal Structure of an ADP Complex of Bacillus subtilis Pyridoxal Kinase Provides Evidence for the Parallel Emergence of Enzyme Activity During Evolution.
J.Mol.Biol., 363, 2006

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