2CH5

Crystal structure of human N-acetylglucosamine kinase in complex with N-acetylglucosamine

Summary for 2CH5

Entry DOI	10.2210/pdb2ch5/pdb
Related	2CH6
Descriptor	NAGK PROTEIN, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... (5 entities in total)
Functional Keywords	transferase, n-acetylglucosamine, glcnac, sugar kinase, ribonuclease h fold, sugar kinase/hsp70/actin superfamily, domain rotation, open conformation, closed conformation, hypothetical protein
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	4
Total formula weight	152505.41
Authors	Weihofen, W.A.,Berger, M.,Chen, H.,Saenger, W.,Hinderlich, S. (deposition date: 2006-03-13, release date: 2006-09-18, Last modification date: 2020-07-29)
Primary citation	Weihofen, W.A.,Berger, M.,Chen, H.,Saenger, W.,Hinderlich, S. Structures of Human N-Acetylglucosamine Kinase in Two Complexes with N-Acetylglucosamine and with Adp/Glucose: Insights Into Substrate Specificity and Regulation. J.Mol.Biol., 364:388-, 2006 Cited by PubMed: 17010375 DOI: 10.1016/J.JMB.2006.08.085 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation