PDB: 30476 件ウェブページステータス検索Chemie searchBIRD

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4UQS	Structure of Bacillus subtilis Nitric Oxide Synthase in complex with 3-Bromo-7-Nitroindazole 分子名称: 3-BROMO-7-NITROINDAZOLE, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Holden, J.K, Poulos, T.L. 登録日 2014-06-24 公開日 2014-09-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Identification of Redox Partners and Development of a Novel Chimeric Bacterial Nitric Oxide Synthase for Structure Activity Analyses. J.Biol.Chem., 289, 2014
4UXN	LSD1(KDM1A)-CoREST in complex with Z-Pro derivative of MC2580 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, REST COREPRESSOR 1, ... 著者 Rodriguez, V, Valente, S, Stazi, G, Lucidi, A, Mercurio, C, Vianello, P, Ciossani, G, Mattevi, A, Botrugno, O.A, Dessanti, P, Minucci, S, Varasi, M, Mai, A. 登録日 2014-08-27 公開日 2015-02-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Pyrrole- and Indole-Containing Tranylcypromine Derivatives as Novel Lysine-Specific Demethylase 1 Inhibitors Active on Cancer Cells Chemmedchem, 6, 2015
4UYU	STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM I IODIDE COMPLEX - 2.3A 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, IODIDE ION, ... 著者 Zebisch, M, Jones, E.Y. 登録日 2014-09-03 公開日 2015-02-25 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Notum Deacylates Wnt Proteins to Suppress Signalling Activity. Nature, 519, 2015
4UQX	Coevolution of the ATPase ClpV, the TssB-TssC Sheath and the Accessory HsiE Protein Distinguishes Two Type VI Secretion Classes 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, HSIE1 著者 Forster, A, Planamente, S, Manoli, E, Lossi, N.S, Freemont, P.S, Filloux, A. 登録日 2014-06-25 公開日 2014-10-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Coevolution of the ATPase Clpv, the Sheath Proteins Tssb and Tssc and the Accessory Protein Tagj/Hsie1 Distinguishes Type Vi Secretion Classes. J.Biol.Chem., 289, 2014
4UT5	Crystal structure of the LecB lectin from Pseudomonas aeruginosa strain PA7 in complex with lewis a tetrasaccharide 分子名称: CALCIUM ION, LECB LECTIN, beta-D-galactopyranose, ... 著者 Boukerb, A.M, Decor, A, Tabaroni, R, Varrot, A, Debentzmann, S, Vidal, S, Imberty, A, Cournoyer, B. 登録日 2014-07-18 公開日 2015-07-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Genomic Rearrangements and Functional Diversification of Leca and Lecb Lectin-Coding Regions Impacting the Efficacy of Glycomimetics Directed Against Pseudomonas Aeruginosa. Front.Microbiol., 7, 2016
4LEA	The Crystal Structure of Pyocin L1 bound to D-mannose at 2.55 Angstroms 分子名称: Pyocin L1, beta-D-mannopyranose 著者 Grinter, R, Roszak, A.W, Mccaughey, L, Cogdell, C.J, Walker, D. 登録日 2013-06-25 公開日 2014-02-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Lectin-Like Bacteriocins from Pseudomonas spp. Utilise D-Rhamnose Containing Lipopolysaccharide as a Cellular Receptor. Plos Pathog., 10, 2014
4V0N	Crystal structure of BBS1N in complex with ARL6DN, soaked with mercury 分子名称: ARF-LIKE SMALL GTPASE, BARDET-BIEDL SYNDROME 1 PROTEIN, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Mourao, A, Lorentzen, E. 登録日 2014-09-17 公開日 2014-11-19 最終更新日 2019-04-03 実験手法 X-RAY DIFFRACTION (3.131 Å) 主引用文献 Structural Basis for Membrane Targeting of the Bbsome by Arl6 Nat.Struct.Mol.Biol., 21, 2014
4LH8	Triazine hydrolase from Arthobacter aurescens modified for maximum expression in E.coli 分子名称: Triazine hydrolase, ZINC ION 著者 Jackson, C.J, Coppin, C.W, Alexandrov, A, Wilding, M, Liu, J.-W, Ubels, J, Paks, M, Carr, P.D, Newman, J, Russell, R.J, Field, M, Weik, M, Oakeshott, J.G, Scott, C. 登録日 2013-07-01 公開日 2014-05-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 300-Fold increase in production of the Zn2+-dependent dechlorinase TrzN in soluble form via apoenzyme stabilization. Appl.Environ.Microbiol., 80, 2014
3WLU	Crystal Structure of human galectin-9 NCRD with Selenolactose 分子名称: 2-(trimethylsilyl)ethyl 4-O-beta-D-galactopyranosyl-6-Se-methyl-6-seleno-beta-D-glucopyranoside, Galectin-9 著者 Makyio, H, Suzuki, T, Ando, H, Yamada, Y, Ishida, H, Kiso, M, Wakatsuki, S, Kato, R. 登録日 2013-11-14 公開日 2014-11-05 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Expanded potential of seleno-carbohydrates as a molecular tool for X-ray structural determination of a carbohydrate-protein complex with single/multi-wavelength anomalous dispersion phasing Bioorg.Med.Chem., 22, 2014
3W3Z	Crystal structure of Kap121p bound to RanGTP 分子名称: GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, Importin subunit beta-3, ... 著者 Kobayashi, J, Matsuura, Y. 登録日 2012-12-28 公開日 2013-04-10 最終更新日 2014-01-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for cell-cycle-dependent nuclear import mediated by the karyopherin Kap121p. J.Mol.Biol., 425, 2013
4LE7	The Crystal Structure of Pyocin L1 at 2.09 Angstroms 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Pyocin L1 著者 Grinter, R, Roszak, A.W, Mccaughey, L, Cogdell, R.J, Walker, D. 登録日 2013-06-25 公開日 2014-02-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Lectin-Like Bacteriocins from Pseudomonas spp. Utilise D-Rhamnose Containing Lipopolysaccharide as a Cellular Receptor. Plos Pathog., 10, 2014
4LND	Crystal structure of human apurinic/apyrimidinic endonuclease 1 with essential Mg2+ cofactor 分子名称: DNA-(apurinic or apyrimidinic site) lyase, MAGNESIUM ION 著者 Manvilla, B.A, Pozharski, E, Toth, E.A, Drohat, A.C. 登録日 2013-07-11 公開日 2013-11-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Structure of human apurinic/apyrimidinic endonuclease 1 with the essential Mg(2+) cofactor. Acta Crystallogr.,Sect.D, 69, 2013
3W3U	Crystal structure of Kap121p mutant R349A/Q350A/D353A/E396A/N430K/D438A/N477A 分子名称: Importin subunit beta-3 著者 Kobayashi, J, Matsuura, Y. 登録日 2012-12-28 公開日 2013-04-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for cell-cycle-dependent nuclear import mediated by the karyopherin Kap121p. J.Mol.Biol., 425, 2013
5TQH	IDH1 R132H mutant in complex with IDH889 分子名称: (4S)-3-[2-({(1S)-1-[5-(4-fluoro-3-methylphenyl)pyrimidin-2-yl]ethyl}amino)pyrimidin-4-yl]-4-(propan-2-yl)-1,3-oxazolidin-2-one, CITRATE ANION, Isocitrate dehydrogenase [NADP] cytoplasmic, ... 著者 Xie, X, Kulathila, R. 登録日 2016-10-24 公開日 2017-01-25 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Optimization of 3-Pyrimidin-4-yl-oxazolidin-2-ones as Allosteric and Mutant Specific Inhibitors of IDH1. ACS Med Chem Lett, 8, 2017
5UFJ	Crystal Structure of Carbonmonoxy Hemoglobin S (Liganded Sickle Cell Hemoglobin) Complexed with GBT Compound 6 分子名称: 5-[(imidazo[1,2-a]pyridin-8-yl)methoxy]-2-methoxypyridine-4-carbaldehyde, CARBON MONOXIDE, Hemoglobin subunit alpha, ... 著者 Partridge, J.R, Choy, R.M, Li, Z, Metcalf, B. 登録日 2017-01-04 公開日 2017-02-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin. ACS Med Chem Lett, 8, 2017
3WTD	Structure of PAXX 分子名称: Uncharacterized protein C9orf142 著者 Ochi, T, Blundell, T.L. 登録日 2014-04-09 公開日 2015-01-21 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair. Science, 347, 2015
4L0M	Crystal structure of a putative 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Borrelia burgdorferi B31 bound to Adenine (Target NYSGRC-029268 ) 分子名称: ADENINE, putative 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 著者 Sampathkumar, P, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2013-05-31 公開日 2013-08-14 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of a putative 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Borrelia burgdorferi B31 bound to Adenine (Target NYSGRC-029268 ) to be published
3WML	Structure of phosphotriesterase mutant (S308L/Y309A) from Agrobacterium radiobacter 分子名称: 1,2-ETHANEDIOL, COBALT (II) ION, FE (II) ION, ... 著者 Jackson, C.J, Carr, P.D, Sugrue, E. 登録日 2013-11-21 公開日 2014-09-24 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 A 5000-fold increase in the specificity of a bacterial phosphotriesterase for malathion through combinatorial active site mutagenesis Plos One, 9, 2014
3WTF	Structure of PAXX 分子名称: Uncharacterized protein C9orf142 著者 Ochi, T, Blundell, T.L. 登録日 2014-04-09 公開日 2015-01-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.451 Å) 主引用文献 DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair. Science, 347, 2015
4LHN	Structure of the N-terminal domain of the Flo1 adhesin (N-Flo1p) from the yeast Saccharomyces cerevisiae, in complex with calcium and mannose 分子名称: CALCIUM ION, Flocculation protein FLO1, alpha-D-mannopyranose 著者 Ielasi, F.S, Willaert, R.G. 登録日 2013-07-01 公開日 2014-09-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Molecular mechanism of flocculation self-recognition in yeast and its role in mating and survival. MBio, 6, 2015
3X1Y	Ras-related protein Rap1B(L9V) with GppNHp 分子名称: CADMIUM ION, GLYCEROL, MAGNESIUM ION, ... 著者 Noguchi, H, Ikegami, T, Park, S.Y, Tame, J.R.H, Unzai, S. 登録日 2014-12-02 公開日 2015-06-03 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.168 Å) 主引用文献 The structure and conformational switching of Rap1B Biochem.Biophys.Res.Commun., 462, 2015
5TP9	Structure of the human GluN1/GluN2A LBD in complex with compound 2 (GNE9178) 分子名称: 7-{[5-chloro-3-(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-N-ethyl-2-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-3-carboxamide, ACETATE ION, CALCIUM ION, ... 著者 Wallweber, H.J.A, Lupardus, P.J. 登録日 2016-10-20 公開日 2016-11-30 最終更新日 2017-02-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile. ACS Med Chem Lett, 8, 2017
3ZOT	Structure of E.coli rhomboid protease GlpG in complex with monobactam L29 (data set 2) 分子名称: CHLORIDE ION, RHOMBOID PROTEASE GLPG, nonyl beta-D-glucopyranoside, ... 著者 Vinothkumar, K.R, Pierrat, O.A, Large, J.M, Freeman, M. 登録日 2013-02-24 公開日 2013-05-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.399 Å) 主引用文献 Structure of Rhomboid Protease in Complex with Beta-Lactam Inhibitors Defines the S2' Cavity. Structure, 21, 2013
5TQE	Factor VIIa in complex with the inhibitor (5R)-5-[(1-aminoisoquinolin-6-yl)amino]-19-(cyclopropylsulfonyl)-3-methyl-13-oxa-3,15-diazatricyclo[14.3.1.1~6,10~]henicosa-1(20),6(21),7,9,16,18-hexaene-4,14-dione 分子名称: (5R)-5-[(1-aminoisoquinolin-6-yl)amino]-19-(cyclopropylsulfonyl)-3-methyl-13-oxa-3,15-diazatricyclo[14.3.1.1~6,10~]henicosa-1(20),6(21),7,9,16,18-hexaene-4,14-dione, CALCIUM ION, Factor VIIa (Heavy Chain), ... 著者 Wei, A. 登録日 2016-10-24 公開日 2017-02-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Design and Synthesis of Novel Meta-Linked Phenylglycine Macrocyclic FVIIa Inhibitors. ACS Med Chem Lett, 8, 2017
3WYF	Crystal structure of Xpo1p-Yrb2p-Gsp1p-GTP complex 分子名称: Exportin-1, GUANOSINE-5'-TRIPHOSPHATE, Gsp1p, ... 著者 Koyama, M, Shirai, N, Matsuura, Y. 登録日 2014-08-26 公開日 2014-11-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Structural insights into how yrb2p accelerates the assembly of the xpo1p nuclear export complex Cell Rep, 9, 2014

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