8FB2
 
 | | HUMAN RETENOID-RELATED ORPHAN RECEPTOR-GAMMA (RORC2) LIGAND-BINDING DOMAIN IN COMPLEX WITH COMPOUND 8 ANDINDAZOLE ACID BOUND IN H12-POCKET | | 分子名称: | (1R,15S)-16-(cyclopropylacetyl)-5-fluoro-20-methyl-9lambda~6~-thia-1,8,16-triazatricyclo[13.3.1.1~3,7~]icosa-3(20),4,6-triene-9,9-dione, 4-[1-(2,6-dichlorobenzoyl)-4-fluoro-1H-indazol-3-yl]benzoic acid, Nuclear receptor ROR-gamma | | 著者 | Vajdos, F.F. | | 登録日 | 2022-11-29 | | 公開日 | 2023-03-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Macrocyclic Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonists.
Acs Med.Chem.Lett., 14, 2023
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8FB0
 | | H64Q Myoglobin in complex with acetamide | | 分子名称: | ACETAMIDE, GLYCEROL, Myoglobin, ... | | 著者 | Powell, S.M, Thomas, L.M, Richter-Addo, G.B. | | 登録日 | 2022-11-29 | | 公開日 | 2023-06-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Interactions of metronidazole and chloramphenicol with myoglobin: Crystal structure of a Mb-acetamide product.
J Porphyr Phthalocyanines, 27, 2023
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8FAX
 | | Fab 1249A8-MERS Stem Helix Complex | | 分子名称: | 1249A8-HC, 1249A8-LC, CHLORIDE ION, ... | | 著者 | Deshpande, A, Schormann, N, Piepenbrink, M.S, Martinez-Sobrido, L, Kobie, J.J, Walter, M.R. | | 登録日 | 2022-11-28 | | 公開日 | 2023-05-03 | | 最終更新日 | 2023-07-19 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure and epitope of a neutralizing monoclonal antibody that targets the stem helix of beta coronaviruses.
Febs J., 290, 2023
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8FA7
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8FA0
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8F9Z
 | | Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with NBD-14204, an HIV-1 gp120 antagonist | | 分子名称: | (5M)-N-{(1S)-2-amino-1-[5-(hydroxymethyl)-1,3-thiazol-2-yl]ethyl}-5-[5-(trifluoromethyl)pyridin-2-yl]-1H-pyrrole-2-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | 著者 | Kwon, Y.D, Kwong, P.D. | | 登録日 | 2022-11-25 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Antiviral Activity and Crystal Structures of HIV-1 gp120 Antagonists.
Int J Mol Sci, 23, 2022
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8F9X
 | | Cyclase-PTE | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | | 著者 | Ji, D, Frkic, R.L, Jackson, C.J. | | 登録日 | 2022-11-24 | | 公開日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Cyclase-PTE
To Be Published
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8F9V
 | | Crystal structure of Ky15.8 Fab in complex with circumsporozoite protein KQPA peptide | | 分子名称: | 1,2-ETHANEDIOL, Circumsporozoite protein KQPA peptide, Ky15.8 Antibody, ... | | 著者 | Thai, E, Prieto, K, Julien, J.P. | | 登録日 | 2022-11-24 | | 公開日 | 2023-11-01 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.
Cell Rep, 42, 2023
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8F9Q
 | | Guinea pig sialic acid esterase (SIAE) | | 分子名称: | Sialic acid acetylesterase, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Ide, D, Gorelik, A, Illes, K, Nagar, B. | | 登録日 | 2022-11-24 | | 公開日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | | 主引用文献 | Guinea pig sialic acid esterase (SIAE)
To Be Published
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8F9N
 | | H64A swMb-iPrNO adduct | | 分子名称: | 2-nitrosopropane, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Herrera, V.E, Thomas, L.M. | | 登録日 | 2022-11-24 | | 公開日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Insights into Nitrosoalkane Binding to Myoglobin Provided by Crystallography of Wild-Type and Distal Pocket Mutant Derivatives.
Biochemistry, 62, 2023
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8F9J
 | | H64A swMb-PrNO adduct | | 分子名称: | 1-nitrosopropane, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Herrera, V.E, Thomas, L.M. | | 登録日 | 2022-11-23 | | 公開日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Insights into Nitrosoalkane Binding to Myoglobin Provided by Crystallography of Wild-Type and Distal Pocket Mutant Derivatives.
Biochemistry, 62, 2023
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8F97
 | | Compound 5 bound to procaspase-6 | | 分子名称: | 1,2-ETHANEDIOL, 2-({[(2M)-[2,3'-bipyridin]-2'-yl]amino}methyl)-5-fluorophenol, CHLORIDE ION, ... | | 著者 | Fan, P, Zhao, Y, Renslo, A.R, Arkin, M.R. | | 登録日 | 2022-11-23 | | 公開日 | 2023-12-13 | | 最終更新日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Systematic Study of Heteroarene Stacking Using a Congeneric Set of Molecular Glues for Procaspase-6.
J.Med.Chem., 66, 2023
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8F94
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8F93
 | | WDR5 covalently modified at Y228 by (R)-2-SF | | 分子名称: | 3-ethynyl-5-{[(3R)-4-{1-[(2-methoxyphenyl)methyl]-1H-benzimidazole-5-carbonyl}-3-methylpiperazin-1-yl]methyl}benzene-1-sulfonyl fluoride, CHLORIDE ION, GLYCEROL, ... | | 著者 | Taunton, J, Craven, G.B, Chen, Y. | | 登録日 | 2022-11-23 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Direct mapping of ligandable tyrosines and lysines in cells with chiral sulfonyl fluoride probes.
Nat.Chem., 15, 2023
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8F91
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8F8Z
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8F8Y
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8F8V
 | | Crystal structure of Nb.X0 | | 分子名称: | Nb.X0 | | 著者 | Goldgur, Y, Ravetch, J, Gupta, A, Kao, K, Andi, B. | | 登録日 | 2022-11-22 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Mechanism of glycoform specificity and in vivo protection by an anti-afucosylated IgG nanobody.
Nat Commun, 14, 2023
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8F8O
 | | Crystal Structure of the Succinyl-diaminopimelate Desuccinylase (DapE) from Acinetobacter baumannii in complex with Succinic and L-Lactic Acids | | 分子名称: | (2S)-2-HYDROXYPROPANOIC ACID, CITRIC ACID, SUCCINIC ACID, ... | | 著者 | Minasov, G, Shuvalova, L, Brunzelle, J.S, Dubrovska, I, Pshenychnyi, S, Satchell, K.J.F, Center for Structural Biology of Infectious Diseases (CSBID), Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2022-11-22 | | 公開日 | 2022-11-30 | | 最終更新日 | 2023-02-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structure of the Succinyl-diaminopimelate Desuccinylase (DapE) from Acinetobacter baumannii in complex with Succinic and L-Lactic Acids
To Be Published
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8F8L
 | | The structure of Rv2173 from M. tuberculosis with DMAP bound | | 分子名称: | (2E,6E)-farnesyl diphosphate synthase, CALCIUM ION, DIMETHYLALLYL DIPHOSPHATE, ... | | 著者 | Johnston, J.M, Allison, T.M, Titterington, J. | | 登録日 | 2022-11-22 | | 公開日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The structure of Rv2173 from M. tuberculosis in APO-, IPP-, and DMAP-bound forms.
To be Published
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8F8K
 | | The structure of Rv2173 from M. tuberculosis with IPP bound | | 分子名称: | (2E,6E)-farnesyl diphosphate synthase, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, ACETATE ION, ... | | 著者 | Johnston, J.M, Allison, T.M, Titterington, J, Beasley, C.P.H. | | 登録日 | 2022-11-22 | | 公開日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The structure of Rv2173 from M. tuberculosis in APO-, IPP-, and DMAP-bound forms.
To be Published
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8F8F
 | | The structure of Rv2173 from M. tuberculosis (APO form) | | 分子名称: | (2E,6E)-farnesyl diphosphate synthase, GLYCEROL, MAGNESIUM ION | | 著者 | Johnston, J.M, Allison, T.M, Titterington, J. | | 登録日 | 2022-11-22 | | 公開日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The structure of Rv2173 from M. tuberculosis in APO-, IPP-, and DMAP-bound forms.
To be Published
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8F88
 | | Crystal structure of PTP1B D181A/Q262A/C215A phosphatase domain with monophosphorylated JAK2 activation loop phosphopeptide | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein kinase JAK2, Tyrosine-protein phosphatase non-receptor type 1 | | 著者 | Morris, R, Kershaw, N.J, Babon, J.J. | | 登録日 | 2022-11-21 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structure guided studies of the interaction between PTP1B and JAK.
Commun Biol, 6, 2023
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8F87
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8F86
 | | SIRT6 bound to an H3K9Ac nucleosome | | 分子名称: | DNA (148-MER), Histone H2A type 1, Histone H2B, ... | | 著者 | Markert, J, Whedon, S, Wang, Z, Cole, P, Farnung, L. | | 登録日 | 2022-11-21 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural Basis of Sirtuin 6-Catalyzed Nucleosome Deacetylation.
J.Am.Chem.Soc., 145, 2023
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