8F86

SIRT6 bound to an H3K9Ac nucleosome

Summary for 8F86

Entry DOI	10.2210/pdb8f86/pdb
EMDB information	28915
Descriptor	Histone H3.2, Histone H4, Histone H2A type 1, ... (9 entities in total)
Functional Keywords	nucleosome, sirtuin6, histone deacylation, h3k9ac, gene regulation
Biological source	Xenopus laevis (African clawed frog) More
Total number of polymer chains	11
Total formula weight	262113.59
Authors	Markert, J.,Whedon, S.,Wang, Z.,Cole, P.,Farnung, L. (deposition date: 2022-11-21, release date: 2023-04-05, Last modification date: 2024-03-13)
Primary citation	Wang, Z.A.,Markert, J.W.,Whedon, S.D.,Yapa Abeywardana, M.,Lee, K.,Jiang, H.,Suarez, C.,Lin, H.,Farnung, L.,Cole, P.A. Structural Basis of Sirtuin 6-Catalyzed Nucleosome Deacetylation. J.Am.Chem.Soc., 145:6811-6822, 2023 Cited by PubMed: 36930461 DOI: 10.1021/jacs.2c13512 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.1 Å)

Structure validation