PDB: 215264 件ウェブページステータス検索Chemie searchBIRD

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4OK5	Crystal Structure of Hepatitis C Virus NS3 Helicase Inhibitor Co-complex with Compound 9 [1-(3-ethynylbenzyl)-1H-indol-3-yl]acetic acid] 分子名称: CALCIUM ION, Serine protease NS3, [1-(3-ethynylbenzyl)-1H-indol-3-yl]acetic acid 著者 Padyana, A.K. 登録日 2014-01-21 公開日 2014-03-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Integrated strategies for identifying leads that target the NS3 helicase of the hepatitis C virus. J.Med.Chem., 57, 2014
2KTP	Structure of the 1,N2-ethenodeoxyguanosine lesion opposite a one-base deletion in duplex DNA 分子名称: DNA (5'-D(*CP*GP*CP*AP*TP*(GNE)P*GP*AP*AP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*TP*TP*CP*AP*TP*GP*CP*G)-3') 著者 Shanmugam, G, Kozekov, I.D, Guengerich, P.F, Rizzo, C.J, Stone, M.P. 登録日 2010-02-05 公開日 2010-03-23 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure of the 1,N(2)-etheno-2'-deoxyguanosine lesion in the 3'-G(epsilon dG)T-5' sequence opposite a one-base deletion. Biochemistry, 49, 2010
4FA1	Crystal Structure of WT MauG in Complex with Pre-Methylamine Dehydrogenase Aged 130 Days. 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, ... 著者 Yukl, E.T, Wilmot, C.M. 登録日 2012-05-21 公開日 2013-03-06 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Diradical intermediate within the context of tryptophan tryptophylquinone biosynthesis. Proc.Natl.Acad.Sci.USA, 110, 2013
1C86	CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B (R47V,D48N) COMPLEXED WITH 2-(OXALYL-AMINO-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRAN-3-CARBOXYLIC ACID 分子名称: 2-(OXALYL-AMINO)-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRAN-3-CARBOXYLIC ACID, PROTEIN (PROTEIN-TYROSINE PHOSPHATASE 1B) 著者 Iversen, L.F, Andersen, H.S, Mortensen, S.B, Moller, N.P. 登録日 2000-04-16 公開日 2000-05-03 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure-based design of a low molecular weight, nonphosphorus, nonpeptide, and highly selective inhibitor of protein-tyrosine phosphatase 1B. J.Biol.Chem., 275, 2000
5OUK	Crystal structure of human AKR1B1 complexed with NADP+ and compound 41 分子名称: 2-[9-fluoranyl-5-(4-methoxyphenyl)-3-methyl-1-oxidanylidene-pyrimido[4,5-c]quinolin-2-yl]ethanoic acid, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Cousido-Siah, A, Ruiz, F.X, Mitschler, A, Metwally, K, Podjarny, A. 登録日 2017-08-24 公開日 2018-05-09 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (0.959 Å) 主引用文献 Design, synthesis, structure-activity relationships and X-ray structural studies of novel 1-oxopyrimido[4,5-c]quinoline-2-acetic acid derivatives as selective and potent inhibitors of human aldose reductase. Eur J Med Chem, 152, 2018
2HKB	NMR Structure of the B-DNA Dodecamer CTCGGCGCCATC 分子名称: 5'-D(*CP*TP*CP*GP*GP*CP*GP*CP*CP*AP*TP*C)-3', 5'-D(*GP*AP*TP*GP*GP*CP*GP*CP*CP*GP*AP*G)-3' 著者 Wang, F, DeMuro, N.E, Elmquist, C.E, Stover, J.S, Rizzo, C.J, Stone, M.P. 登録日 2006-07-03 公開日 2006-10-03 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Base-displaced intercalated structure of the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in the recognition sequence of the NarI restriction enzyme, a hotspot for -2 bp deletions. J.Am.Chem.Soc., 128, 2006
4FA4	Crystal Structure of WT MauG in Complex with Pre-Methylamine Dehydrogenase Aged 10 Days 分子名称: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... 著者 Yukl, E.T, Wilmot, C.M. 登録日 2012-05-21 公開日 2013-03-06 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Diradical intermediate within the context of tryptophan tryptophylquinone biosynthesis. Proc.Natl.Acad.Sci.USA, 110, 2013
4OJQ	Crystal Structure of Hepatitis C Virus NS3 Helicase Inhibitor Co-complex with Fragment 1 [(5-bromo-1H-indol-3-yl)acetic acid] 分子名称: (5-bromo-1H-indol-3-yl)acetic acid, CALCIUM ION, Serine protease NS3 著者 Padyana, A.K. 登録日 2014-01-21 公開日 2014-03-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Integrated strategies for identifying leads that target the NS3 helicase of the hepatitis C virus. J.Med.Chem., 57, 2014
4FA5	Crystal Structure of WT MauG in Complex with Pre-Methylamine Dehydrogenase Aged 20 Days 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... 著者 Yukl, E.T, Wilmot, C.M. 登録日 2012-05-21 公開日 2013-03-06 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Diradical intermediate within the context of tryptophan tryptophylquinone biosynthesis. Proc.Natl.Acad.Sci.USA, 110, 2013
3RLM	Structure of the W199F MauG/pre-Methylamine Dehydrogenase complex after treatment with hydrogen peroxide 分子名称: ACETATE ION, CALCIUM ION, HEME C, ... 著者 Yukl, E.T, Wilmot, C.M. 登録日 2011-04-19 公開日 2011-10-05 最終更新日 2011-10-26 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Mutagenesis of tryptophan199 suggests that hopping is required for MauG-dependent tryptophan tryptophylquinone biosynthesis. Proc.Natl.Acad.Sci.USA, 108, 2011
4FA9	Crystal Structure of WT MauG in Complex with Pre-Methylamine Dehydrogenase Aged 30 Days 分子名称: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... 著者 Yukl, E.T, Wilmot, C.M. 登録日 2012-05-21 公開日 2013-03-06 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Diradical intermediate within the context of tryptophan tryptophylquinone biosynthesis. Proc.Natl.Acad.Sci.USA, 110, 2013
4KRS	Tankyrase-1 complexed with small molecule inhibitor 分子名称: 4-tert-butyl-N-(5,6-dihydro[1,3]thiazolo[2,3-c][1,2,4]triazol-3-yl)benzamide, SULFATE ION, Tankyrase-1, ... 著者 Stams, T, Kirby, C. 登録日 2013-05-17 公開日 2013-08-28 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Structure-Efficiency Relationship of [1,2,4]Triazol-3-ylamines as Novel Nicotinamide Isosteres that Inhibit Tankyrases. J.Med.Chem., 56, 2013
3SYM	Glycogen Phosphorylase b in complex with 3 -C-(hydroxymethyl)-beta-D-glucopyranonucleoside of 5-fluorouracil 分子名称: 5-fluoro-1-[3-C-(hydroxymethyl)-beta-D-glucopyranosyl]pyrimidine-2,4(1H,3H)-dione, Glycogen phosphorylase, muscle form 著者 Skamnaki, V.T, Katsandi, A.L, Kontou, M, Leonidas, D.D. 登録日 2011-07-18 公開日 2012-02-15 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 3'-Axial CH(2) OH Substitution on Glucopyranose does not Increase Glycogen Phosphorylase Inhibitory Potency. QM/MM-PBSA Calculations Suggest Why. Chem.Biol.Drug Des., 79, 2012
4DGY	Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody HCV1, C2 form 分子名称: CHLORIDE ION, E2 peptide, GLYCEROL, ... 著者 Kong, L, Wilson, I.A, Law, M. 登録日 2012-01-27 公開日 2012-05-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.798 Å) 主引用文献 Structural basis of hepatitis C virus neutralization by broadly neutralizing antibody HCV1. Proc.Natl.Acad.Sci.USA, 109, 2012
3N5U	Crystal structure of an Rb C-terminal peptide bound to the catalytic subunit of PP1 分子名称: CHLORIDE ION, MANGANESE (II) ION, Retinoblastoma-associated protein, ... 著者 Hirschi, A.M, Cecchini, M, Steinhardt, R.C, Dick, F.A, Rubin, S.M. 登録日 2010-05-25 公開日 2010-08-11 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 An overlapping kinase and phosphatase docking site regulates activity of the retinoblastoma protein. Nat.Struct.Mol.Biol., 17, 2010
1Y9H	Methylation of cytosine at C5 in a CpG sequence context causes a conformational switch of a benzo[a]pyrene diol epoxide-N2-guanine adduct in DNA from a minor groove alignment to intercalation with base displacement 分子名称: 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE, 5'-D(*CP*CP*AP*TP*(5CM)P*(BPG)P*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*CP*GP*AP*TP*GP*G)-3' 著者 Zhang, N, Lin, C, Huang, X, Kolbanovskiy, A, Hingerty, B.E, Amin, S, Broyde, S, Geacintov, N.E, Patel, D.J. 登録日 2004-12-15 公開日 2005-03-22 最終更新日 2024-04-24 実験手法 SOLUTION NMR 主引用文献 Methylation of cytosine at C5 in a CpG sequence context causes a conformational switch of a benzo[a]pyrene diol epoxide-N2-guanine adduct in DNA from a minor groove alignment to intercalation with base displacement. J.Mol.Biol., 346, 2005
4OKS	Crystal Structure of Hepatitis C Virus NS3 Helicase Inhibitor Co-complex with Compound 19 [[6-(3,5-diaminophenyl)-1-(2-methoxy-5-nitrobenzyl)-1H-indol-3-yl]acetic acid] 分子名称: CALCIUM ION, Serine protease NS3, [6-(3,5-diaminophenyl)-1-(2-methoxy-5-nitrobenzyl)-1H-indol-3-yl]acetic acid 著者 Padyana, A.K. 登録日 2014-01-22 公開日 2014-03-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Integrated strategies for identifying leads that target the NS3 helicase of the hepatitis C virus. J.Med.Chem., 57, 2014
2I0E	Structure of catalytic domain of human protein kinase C beta II complexed with a bisindolylmaleimide inhibitor 分子名称: 3-{1-[3-(DIMETHYLAMINO)PROPYL]-2-METHYL-1H-INDOL-3-YL}-4-(2-METHYL-1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE, Protein Kinase C-beta II 著者 Grodsky, N.B, Love, R.L. 登録日 2006-08-10 公開日 2006-11-14 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of the Catalytic Domain of Human Protein Kinase C beta II Complexed with a Bisindolylmaleimide Inhibitor Biochemistry, 45, 2006
4F50	Y-family DNA polymerase chimera Dbh-Dbh-Dpo4 分子名称: CALCIUM ION, DNA (5'-D(*CP*CP*GP*CP*CP*T*GP*GP*CP*TP*TP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*AP*AP*GP*CP*CP*GP*GP*C)-3'), ... 著者 Pata, J.D, Wilson, R.C. 登録日 2012-05-11 公開日 2013-01-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.215 Å) 主引用文献 Y-family polymerase conformation is a major determinant of fidelity and translesion specificity. Structure, 21, 2013
4FB1	Crystal Structure of WT MauG in Complex with Pre-Methylamine Dehydrogenase Aged 60 Days 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, HEME C, ... 著者 Yukl, E.T, Wilmot, C.M. 登録日 2012-05-22 公開日 2013-03-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Diradical intermediate within the context of tryptophan tryptophylquinone biosynthesis. Proc.Natl.Acad.Sci.USA, 110, 2013
4F6M	Crystal structure of Kaiso zinc finger DNA binding domain in complex with Kaiso binding site DNA 分子名称: DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), Transcriptional regulator Kaiso, ... 著者 Buck-Koehntop, B.A, Stanfield, R.L, Ekiert, D.C, Martinez-Yamout, M.A, Dyson, H.J, Wilson, I.A, Wright, P.E. 登録日 2012-05-15 公開日 2012-09-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso. Proc.Natl.Acad.Sci.USA, 109, 2012
4FAV	Crystal Structure of WT MauG in Complex with Pre-Methylamine Dehydrogenase Aged 50 Days 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... 著者 Yukl, E.T, Wilmot, C.M. 登録日 2012-05-22 公開日 2013-03-06 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Diradical intermediate within the context of tryptophan tryptophylquinone biosynthesis. Proc.Natl.Acad.Sci.USA, 110, 2013
1LVZ	METARHODOPSIN II BOUND STRUCTURE OF C-TERMINAL PEPTIDE OF ALPHA-SUBUNIT OF TRANSDUCIN 分子名称: Guanine nucleotide-binding protein G(T), alpha-1 subunit 著者 Koenig, B.W, Kontaxis, G, Mitchell, D.C, Louis, J.M, Litman, B.J, Bax, A. 登録日 2002-05-30 公開日 2002-09-11 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure and orientation of a G protein fragment in the receptor bound state from residual dipolar couplings. J.Mol.Biol., 322, 2002
4OFB	Crystal structure of human BRCA1 BRCT in complex with nonphosphopeptide inhibitor 分子名称: Breast cancer type 1 susceptibility protein, nonphosphopeptide inhibitor 著者 Sun, L, Edwards, R.A, Glover, J.N.M. 登録日 2014-01-14 公開日 2015-04-15 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Peptide Library Approach to Uncover Phosphomimetic Inhibitors of the BRCA1 C-Terminal Domain. Acs Chem.Biol., 10, 2015
4FAN	Crystal Structure of WT MauG in Complex with Pre-Methylamine Dehydrogenase Aged 40 Days 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, ... 著者 Yukl, E.T, Wilmot, C.M. 登録日 2012-05-22 公開日 2013-03-06 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Diradical intermediate within the context of tryptophan tryptophylquinone biosynthesis. Proc.Natl.Acad.Sci.USA, 110, 2013

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