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6ZIE
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BU of 6zie by Molmil
Crystal structure of MCL-1 in complex with a neutralizing Alphabody CMPX-383B
分子名称: CMPX-383B, Induced myeloid leukemia cell differentiation protein Mcl-1, ZINC ION
著者Pannecoucke, E, Savvides, S.N, Desmet, J, Lasters, I.
登録日2020-06-25
公開日2021-04-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Cell-penetrating Alphabody protein scaffolds for intracellular drug targeting.
Sci Adv, 7, 2021
7R9D
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BU of 7r9d by Molmil
Crystal structure of Nb_0 in complex with Fab_8D3
分子名称: Fab 8D3 heavy chain, Fab 8D3 light chain, Nanobody N0
著者Wu, X.D, Rapoport, T.A.
登録日2021-06-29
公開日2021-10-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Cryo-EM structure determination of small proteins by nanobody-binding scaffolds (Legobodies).
Proc.Natl.Acad.Sci.USA, 118, 2021
4NXE
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BU of 4nxe by Molmil
Crystal structure of iLOV-I486(2LT) at pH 6.5
分子名称: FLAVIN MONONUCLEOTIDE, Phototropin-2
著者Wang, J, Liu, X, Li, J.
登録日2013-12-09
公開日2014-09-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.103 Å)
主引用文献Significant expansion of fluorescent protein sensing ability through the genetic incorporation of superior photo-induced electron-transfer quenchers.
J.Am.Chem.Soc., 136, 2014
7RFB
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BU of 7rfb by Molmil
Crystal structure of broadly neutralizing antibody mAb1198 in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Flyak, A.I, Bjorkman, P.J.
登録日2021-07-14
公開日2022-01-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization.
Immunity, 55, 2022
5JLP
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BU of 5jlp by Molmil
Crystal structure of Mycobacterium avium SerB2 in complex with serine at ACT domain
分子名称: 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, MAGNESIUM ION, ...
著者Shree, S, Ramachandran, R.
登録日2016-04-27
公開日2017-05-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.495 Å)
主引用文献Crystal structure of Mycobacterium avium SerB2 in complex with serine at ACT domain
To be published
5UKD
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BU of 5ukd by Molmil
PH INFLUENCES FLUORIDE COORDINATION NUMBER OF THE ALFX PHOSPHORYL TRANSFER TRANSITION STATE ANALOG
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CYTIDINE-5'-MONOPHOSPHATE, ...
著者Schlichting, I, Reinstein, J.
登録日1999-04-18
公開日1999-08-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献pH influences fluoride coordination number of the AlFx phosphoryl transfer transition state analog.
Nat.Struct.Biol., 6, 1999
1CLI
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BU of 1cli by Molmil
X-RAY CRYSTAL STRUCTURE OF AMINOIMIDAZOLE RIBONUCLEOTIDE SYNTHETASE (PURM), FROM THE E. COLI PURINE BIOSYNTHETIC PATHWAY, AT 2.5 A RESOLUTION
分子名称: PROTEIN (PHOSPHORIBOSYL-AMINOIMIDAZOLE SYNTHETASE), SULFATE ION
著者Li, C, Kappock, T.J, Stubbe, J, Weaver, T.M, Ealick, S.E.
登録日1999-04-28
公開日1999-10-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献X-ray crystal structure of aminoimidazole ribonucleotide synthetase (PurM), from the Escherichia coli purine biosynthetic pathway at 2.5 A resolution.
Structure Fold.Des., 7, 1999
7RFC
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BU of 7rfc by Molmil
Crystal structure of broadly neutralizing antibody mAb1382 in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Flyak, A.I, Bjorkman, P.J.
登録日2021-07-14
公開日2022-01-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization.
Immunity, 55, 2022
6T61
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BU of 6t61 by Molmil
A model of the EIAV CA-SP hexamer (C2) from Gag-deltaMA tubes assembled at pH8
分子名称: Gag polyprotein
著者Dick, R.A, Xu, C, Morado, D.R, Kravchuk, V, Ricana, C.L, Lyddon, T.D, Broad, A.M, Feathers, J.R, Johnson, M.C, Vogt, V.M, Perilla, J.R, Briggs, J.A.G, Schur, F.K.M.
登録日2019-10-17
公開日2020-01-15
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly.
Plos Pathog., 16, 2020
5JLR
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BU of 5jlr by Molmil
Crystal structure of Mycobacterium avium SerB2 with serine present at slightly different position near ACT domain
分子名称: 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, MAGNESIUM ION, ...
著者Shree, S, Agrawal, A, Dubey, S, Ramachandran, R.
登録日2016-04-27
公開日2017-05-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.261 Å)
主引用文献Crystal structure of Mycobacterium avium SerB2 with serine present at slightly different position near ACT domain
To be published
7PGB
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BU of 7pgb by Molmil
NaV_Ae1/Sp1CTD_pore-SAT09 complex
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 4-NITROBENZOIC ACID, ...
著者Lolicato, M, Arrigoni, C.
登録日2021-08-13
公開日2022-06-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022
7PG8
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BU of 7pg8 by Molmil
NaV_Ae1/Sp1CTD_pore-ANT05 complex
分子名称: ANT05 H12 fab fragment, heavy chain, light chain, ...
著者Lolicato, M, Arrigoni, C.
登録日2021-08-13
公開日2022-06-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022
7PGF
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BU of 7pgf by Molmil
Calcium-selective Sp1 channel pore domain only
分子名称: Ion transporter
著者Lolicato, M, Arrigoni, C.
登録日2021-08-13
公開日2022-06-08
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022
5T93
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BU of 5t93 by Molmil
Immunoglobulin light chain variable domain AL-T05
分子名称: ACETATE ION, ALT-05 immunoglobulin light chain variable domain from light chain amyloidosis patient, ZINC ION
著者Ramirez-Alvarado, M, Blancas-Mejia, L.M.
登録日2016-09-09
公開日2017-09-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Differences in Protein Concentration Dependence for Nucleation and Elongation in Light Chain Amyloid Formation.
Biochemistry, 56, 2017
7PGI
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BU of 7pgi by Molmil
NaVAb1p (bicelles)
分子名称: ACETATE ION, Ion transport protein, MAGNESIUM ION, ...
著者Lolicato, M, Arrigoni, C.
登録日2021-08-14
公開日2022-06-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.638 Å)
主引用文献Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022
7PGH
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BU of 7pgh by Molmil
NaVAe1/Sp1CTDp (DDM)
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, DODECAETHYLENE GLYCOL, DODECANE, ...
著者Lolicato, M, Arrigoni, C.
登録日2021-08-14
公開日2022-06-15
最終更新日2022-06-29
実験手法X-RAY DIFFRACTION (4.194 Å)
主引用文献Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022
7PGG
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BU of 7pgg by Molmil
NaVAb1p detergent (DM)
分子名称: 2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}ethyl heptadecanoate, Ion transport protein
著者Lolicato, M, Arrigoni, C.
登録日2021-08-13
公開日2022-06-15
最終更新日2022-06-29
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022
3J7N
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BU of 3j7n by Molmil
Virus model of brome mosaic virus (second half data set)
分子名称: Capsid protein
著者Wang, Z, Hryc, C, Bammes, B, Afonine, P.V, Jakana, J, Chen, D.H, Liu, X, Baker, M.L, Kao, C, Ludtke, S.J, Schmid, M.F, Adams, P.D, Chiu, W.
登録日2014-07-18
公開日2014-09-10
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献An atomic model of brome mosaic virus using direct electron detection and real-space optimization.
Nat Commun, 5, 2014
3J7L
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BU of 3j7l by Molmil
Full virus map of brome mosaic virus
分子名称: Capsid protein
著者Wang, Z, Hryc, C, Bammes, B, Afonine, P.V, Jakana, J, Chen, D.H, Liu, X, Baker, M.L, Kao, C, Ludtke, S.J, Schmid, M.F, Adams, P.D, Chiu, W.
登録日2014-07-18
公開日2014-09-10
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献An atomic model of brome mosaic virus using direct electron detection and real-space optimization.
Nat Commun, 5, 2014
8QTQ
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BU of 8qtq by Molmil
Thermostable WW domain
分子名称: WW domain
著者Kovermann, M, Thomas, F.
登録日2023-10-13
公開日2024-07-03
実験手法SOLUTION NMR
主引用文献Thermostable WW-Domain Scaffold to Design Functional beta-Sheet Miniproteins.
J.Am.Chem.Soc., 2024
5O94
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BU of 5o94 by Molmil
X-ray structure of a zinc binding GB1 mutant
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, GLYCEROL, ...
著者Rothlisberger, U, Bozkurt, E, Hovius, R, Perez, M.A.S, Browning, N.J.
登録日2017-06-15
公開日2018-04-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Genetic Algorithm Based Design and Experimental Characterization of a Highly Thermostable Metalloprotein.
J. Am. Chem. Soc., 140, 2018
5IWC
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BU of 5iwc by Molmil
Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 3 [4-(3-([1,1'-Biphenyl]-3-yl)ureido)-2-hydroxybenzoic acid]
分子名称: 4-{[([1,1'-biphenyl]-3-yl)carbamoyl]amino}-2-hydroxybenzoic acid, O-phosphoserine sulfhydrylase, PYRIDOXAL-5'-PHOSPHATE
著者Schnell, R, Maric, S, Lindqvist, Y, Schneider, G.
登録日2016-03-22
公開日2016-08-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.
J.Med.Chem., 59, 2016
5TTD
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BU of 5ttd by Molmil
Minor pilin FctB from S. pyogenes with engineered intramolecular isopeptide bond
分子名称: FORMIC ACID, Maltose-binding periplasmic protein,Pilin isopeptide linkage domain protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Young, P.G, Kwon, H, Squire, C.J, Baker, E.N.
登録日2016-11-02
公開日2017-03-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Engineering a Lys-Asn isopeptide bond into an immunoglobulin-like protein domain enhances its stability.
Sci Rep, 7, 2017
6TY9
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BU of 6ty9 by Molmil
In situ structure of BmCPV RNA dependent RNA polymerase at initiation state
分子名称: MAGNESIUM ION, Non-template RNA (5'-D(*(GTA))-R(P*GP*UP*AP*AP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3'), RNA-dependent RNA Polymerase, ...
著者Cui, Y.X, Zhang, Y.N, Sun, J.C, Zhou, Z.H.
登録日2019-08-08
公開日2019-11-20
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Conservative transcription in three steps visualized in a double-stranded RNA virus.
Nat.Struct.Mol.Biol., 26, 2019
6TZ1
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BU of 6tz1 by Molmil
In situ structure of BmCPV RNA-dependent RNA polymerase at early-elongation state
分子名称: Non-template RNA (5'-D(*(GTA))-R(P*GP*UP*A)-3'), RNA-dependent RNA Polymerase, Template RNA (5'-R(P*AP*GP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ...
著者Cui, Y.X, Zhang, Y.N, Sun, J.C, Zhou, Z.H.
登録日2019-08-09
公開日2019-11-20
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Conservative transcription in three steps visualized in a double-stranded RNA virus.
Nat.Struct.Mol.Biol., 26, 2019

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