PDB: 608 件ウェブページステータス検索Chemie searchBIRD

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7OBY	Crystal structure of 14-3-3 sigma in complex with SSBP4 phosphopeptide and stabilizer Fusicoccin-A 分子名称: 14-3-3 protein sigma, CHLORIDE ION, FUSICOCCIN, ... 著者 Centorrino, F, Andlovic, B, Ottmann, C. 登録日 2021-04-24 公開日 2022-05-04 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023
7OPW	Ternary complex of 14-3-3 sigma, Estrogen Receptor alfa phosphopeptide, and WQ136 分子名称: 14-3-3 protein sigma, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... 著者 Centorrino, F, Ottmann, C. 登録日 2021-06-01 公開日 2022-06-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published
7OQ7	Ternary complex of 14-3-3 sigma, Estrogen Receptor alfa phosphopeptide, and WQ162 分子名称: 14-3-3 protein sigma, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... 著者 Centorrino, F, Ottmann, C. 登録日 2021-06-02 公開日 2022-06-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published
7OQ8	Ternary complex of 14-3-3 sigma, Estrogen Receptor alfa phosphopeptide, and WQ178 分子名称: 14-3-3 protein sigma, CHLORIDE ION, Estrogen receptor, ... 著者 Centorrino, F, Ottmann, C. 登録日 2021-06-02 公開日 2022-06-22 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published
7OQ9	Ternary complex of 14-3-3 sigma, Pin1pS72 phosphopeptide, and WQ136 分子名称: 14-3-3 protein sigma, CHLORIDE ION, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... 著者 Centorrino, F, Ottmann, C. 登録日 2021-06-02 公開日 2022-08-10 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published
7OQA	Ternary complex of 14-3-3 sigma, Pin1pS72 phosphopeptide, and WQ162 分子名称: 14-3-3 protein sigma, CHLORIDE ION, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... 著者 Centorrino, F, Ottmann, C. 登録日 2021-06-02 公開日 2022-08-10 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published
7OQG	Ternary complex of 14-3-3 sigma, Amot-p130 phosphopeptide, and WQ136 分子名称: 14-3-3 protein sigma, Amot-p130 phosphopeptide (pS175), BETA-MERCAPTOETHANOL, ... 著者 Centorrino, F, Ottmann, C. 登録日 2021-06-03 公開日 2022-06-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published
7OQJ	Ternary complex of 14-3-3 sigma, Amot-p130 phosphopeptide, and WQ162 分子名称: 14-3-3 protein sigma, Amot-p130 phosphopeptide (pS175), CHLORIDE ION, ... 著者 Centorrino, F, Ottmann, C. 登録日 2021-06-03 公開日 2022-06-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published
7OQS	Ternary complex of 14-3-3 sigma, Amot-p130 phosphopeptide, and WQ177 分子名称: 14-3-3 protein sigma, 2-(1,3-benzodioxol-5-yl)-~{N}-[(5-carbamimidoyl-3-phenyl-thiophen-2-yl)methyl]ethanamide, Amot-p130 phosphopeptide (pS175), ... 著者 Centorrino, F, Ottmann, C. 登録日 2021-06-04 公開日 2022-06-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.34 Å) 主引用文献 A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published
7OQU	Ternary complex of 14-3-3 sigma, Amot-p130 phosphopeptide, and WQ180 分子名称: (2~{S},3~{S})-~{N}-[(5-carbamimidoyl-3-phenyl-thiophen-2-yl)methyl]-3-methyl-2,3-dihydro-1-benzofuran-2-carboxamide, 14-3-3 protein sigma, Amot-p130 phosphopeptide (pS175), ... 著者 Centorrino, F, Ottmann, C. 登録日 2021-06-04 公開日 2022-06-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published
7OQW	Ternary complex of 14-3-3 sigma, Amot-p130 phosphopeptide, and WQ178 分子名称: 14-3-3 protein sigma, Amot-p130 phosphopeptide (pS175), MAGNESIUM ION, ... 著者 Centorrino, F, Ottmann, C. 登録日 2021-06-04 公開日 2022-06-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published
7OR3	Ternary complex of 14-3-3 sigma, NotchpS1917 phosphopeptide, and WQ136 分子名称: 14-3-3 protein sigma, CHLORIDE ION, MAGNESIUM ION, ... 著者 Centorrino, F, Wu, Q, Ottmann, C. 登録日 2021-06-04 公開日 2022-06-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published
7OR5	Ternary complex of 14-3-3 sigma, NotchpS1917 phosphopeptide, and WQ162 分子名称: 14-3-3 protein sigma, CHLORIDE ION, Neurogenic locus notch homolog protein 4, ... 著者 Centorrino, F, Wu, Q, Ottmann, C. 登録日 2021-06-04 公開日 2022-07-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published
7OR7	Ternary complex of 14-3-3 sigma, NotchpS1917 phosphopeptide, and WQ178 分子名称: 14-3-3 protein sigma, CHLORIDE ION, MAGNESIUM ION, ... 著者 Centorrino, F, Wu, Q, Ottmann, C. 登録日 2021-06-04 公開日 2022-07-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published
7OR8	Ternary complex of 14-3-3 sigma, p27pT198 phosphopeptide, and WQ136 分子名称: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ... 著者 Centorrino, F, Wu, Q, Ottmann, C. 登録日 2021-06-04 公開日 2022-06-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published
7ORG	Ternary complex of 14-3-3 sigma, p27pT198 phosphopeptide, and WQ162 分子名称: 14-3-3 protein sigma, CHLORIDE ION, Cyclin-dependent kinase inhibitor 1B, ... 著者 Centorrino, F, Wu, Q, Ottmann, C. 登録日 2021-06-05 公開日 2022-06-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published
7ORH	Ternary complex of 14-3-3 sigma, p27pT198 phosphopeptide, and WQ178 分子名称: 14-3-3 protein sigma, CHLORIDE ION, Cyclin-dependent kinase inhibitor 1B, ... 著者 Centorrino, F, Wu, Q, Ottmann, C. 登録日 2021-06-05 公開日 2022-06-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published
7ORS	Ternary complex of 14-3-3 sigma, p27pT198 phosphopeptide, and WQ147 分子名称: (4~{S})-~{N}-[(5-carbamimidoyl-3-phenyl-thiophen-2-yl)methyl]oxepane-4-carboxamide, 14-3-3 protein sigma, CHLORIDE ION, ... 著者 Centorrino, F, Wu, Q, Ottmann, C. 登録日 2021-06-06 公開日 2022-06-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published
7ORT	Ternary complex of 14-3-3 sigma, p27pT198 phosphopeptide, and WQ176 分子名称: 14-3-3 protein sigma, CHLORIDE ION, Cyclin-dependent kinase inhibitor 1B, ... 著者 Centorrino, F, Wu, Q, Ottmann, C. 登録日 2021-06-06 公開日 2022-06-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published
7PWT	Crystal structure of 14-3-3 sigma in complex with a C-terminal Estrogen Receptor alpha phosphopeptide, stabilised by pyrrolidone derivative 228 分子名称: (2~{R})-1-(2-hydroxyphenyl)-2-(4-nitrophenyl)-4-oxidanyl-3-(phenylcarbonyl)-2~{H}-pyrrol-5-one, 14-3-3 protein sigma, C-terminus of Estrogen receptor alpha, ... 著者 Andrei, S.A, Bosica, F, O'Mahony, G, Ottmann, C. 登録日 2021-10-07 公開日 2022-12-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.312 Å) 主引用文献 Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3-3 Protein-Protein Interaction. J.Med.Chem., 65, 2022
7PWZ	Crystal structure of 14-3-3 sigma in complex with a C-terminal Estrogen Receptoralpha phosphopeptide, stabilised by Pyrrolidone1 derivative 228 分子名称: 14-3-3 protein sigma, 2-oxidanyl-5-[(2~{R})-4-oxidanyl-5-oxidanylidene-2-(1-oxidanylidene-3~{H}-2-benzofuran-5-yl)-3-(phenylcarbonyl)-2~{H}-pyrrol-1-yl]benzoic acid, C-terminus of Estrogen receptor alpha, ... 著者 Andrei, S.A, Bosica, F, O'Mahony, G, Ottmann, C. 登録日 2021-10-07 公開日 2022-12-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3-3 Protein-Protein Interaction. J.Med.Chem., 65, 2022
7Q16	Human 14-3-3 zeta fused to the BAD peptide including phosphoserine-74 分子名称: 14-3-3 protein zeta/delta,Bcl2-associated agonist of cell death 著者 Sluchanko, N.N, Tugaeva, K.V, Gushchin, I, Remeeva, A, Kovalev, K, Cooley, R.B. 登録日 2021-10-18 公開日 2021-11-17 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.356 Å) 主引用文献 Crystal structure of human 14-3-3 zeta complexed with the noncanonical phosphopeptide from proapoptotic BAD. Biochem.Biophys.Res.Commun., 583, 2021
7QI1	Crystal structure of human 14-3-3 protein beta in complex with CFTR peptide pS753pS768 and PPI stabilizer CY007424 分子名称: 14-3-3 protein theta, ARGININE, Cystic fibrosis transmembrane conductance regulator, ... 著者 Stevers, L.M, Ottmann, C. 登録日 2021-12-14 公開日 2022-05-25 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Macrocycle-stabilization of its interaction with 14-3-3 increases plasma membrane localization and activity of CFTR. Nat Commun, 13, 2022
7QIK	SARS-CoV-2 Nucleocapsid phosphopeptide 193-200 bound to human 14-3-3 sigma 分子名称: 14-3-3 protein sigma, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BROMIDE ION, ... 著者 Sluchanko, N.N, Tugaeva, K.V, Smith, J.L.R, Antson, A.A. 登録日 2021-12-15 公開日 2021-12-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 SARS-CoV-2 Nucleocapsid phosphopeptide 193-200 bound to human 14-3-3 sigma To Be Published
7QIP	SARS-CoV-2 Nucleocapsid phosphopeptide 201-210 bound to human 14-3-3 sigma 分子名称: 14-3-3 protein sigma, ARG-GLY-TPO-SER-PRO-ALA-ARG-MET, CHLORIDE ION 著者 Sluchanko, N.N, Tugaeva, K.V, Smith, J.L.R, Antson, A.A. 登録日 2021-12-15 公開日 2021-12-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 SARS-CoV-2 Nucleocapsid phosphopeptide 193-200 bound to human 14-3-3 sigma To Be Published

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