7ORH

Ternary complex of 14-3-3 sigma, p27pT198 phosphopeptide, and WQ178

Summary for 7ORH

Entry DOI	10.2210/pdb7orh/pdb
Descriptor	14-3-3 protein sigma, Cyclin-dependent kinase inhibitor 1B, ~{N}-[(5-carbamimidoyl-3-phenyl-thiophen-2-yl)methyl]-1~{H}-indole-6-carboxamide, ... (6 entities in total)
Functional Keywords	protein-peptide complex small-molecule, signaling protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	30582.21
Authors	Centorrino, F.,Wu, Q.,Ottmann, C. (deposition date: 2021-06-05, release date: 2022-06-22, Last modification date: 2024-01-31)
Primary citation	Centorrino, F.,Wu, Q.,Cossar, P.,Brunsveld, L.,Ottmann, C. A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published,
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation