5KHH
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![BU of 5khh by Molmil](/molmil-images/mine/5khh) | HCN2 CNBD in complex with inosine-3', 5'-cyclic monophosphate (cIMP) | 分子名称: | Inosine-3',5'-cyclic monophosphate, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | 著者 | Ng, L.C.T, Putrenko, I, Baronas, V, Van Petegem, F, Accili, E.A. | 登録日 | 2016-06-14 | 公開日 | 2016-09-14 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Cyclic Purine and Pyrimidine Nucleotides Bind to the HCN2 Ion Channel and Variably Promote C-Terminal Domain Interactions and Opening. Structure, 24, 2016
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5KHK
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![BU of 5khk by Molmil](/molmil-images/mine/5khk) | HCN2 CNBD in complex with 2-aminopurine riboside-3', 5'-cyclic monophosphate (2-NH2-cPuMP) | 分子名称: | 2-Aminopurine riboside-3',5'-cyclic monophosphate, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | 著者 | Ng, L.C.T, Putrenko, I, Baronas, V, Van Petegem, F, Accili, E.A. | 登録日 | 2016-06-14 | 公開日 | 2016-09-14 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Cyclic Purine and Pyrimidine Nucleotides Bind to the HCN2 Ion Channel and Variably Promote C-Terminal Domain Interactions and Opening. Structure, 24, 2016
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5KHJ
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![BU of 5khj by Molmil](/molmil-images/mine/5khj) | HCN2 CNBD in complex with uridine-3', 5'-cyclic monophosphate (cUMP) | 分子名称: | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2, Uridine-3',5'-cyclic monophosphate | 著者 | Ng, L.C.T, Putrenko, I, Baronas, V, Van Petegem, F, Accili, E.A. | 登録日 | 2016-06-14 | 公開日 | 2016-09-14 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Cyclic Purine and Pyrimidine Nucleotides Bind to the HCN2 Ion Channel and Variably Promote C-Terminal Domain Interactions and Opening. Structure, 24, 2016
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6ZZ9
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![BU of 6zz9 by Molmil](/molmil-images/mine/6zz9) | |
5KHG
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![BU of 5khg by Molmil](/molmil-images/mine/5khg) | HCN2 CNBD in complex with cytidine-3', 5'-cyclic monophosphate (cCMP) | 分子名称: | 4-amino-1-[(2S,4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]pyrimidin-2(1H)-one, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | 著者 | Ng, L.C.T, Putrenko, I, Baronas, V, Van Petegem, F, Accili, E.A. | 登録日 | 2016-06-14 | 公開日 | 2016-09-14 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.241 Å) | 主引用文献 | Cyclic Purine and Pyrimidine Nucleotides Bind to the HCN2 Ion Channel and Variably Promote C-Terminal Domain Interactions and Opening. Structure, 24, 2016
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6HVN
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![BU of 6hvn by Molmil](/molmil-images/mine/6hvn) | CdaA-APO Y187A Mutant | 分子名称: | CHLORIDE ION, Diadenylate cyclase, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | 著者 | Heidemann, J.L, Neumann, P, Ficner, R. | 登録日 | 2018-10-11 | 公開日 | 2019-06-05 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.234 Å) | 主引用文献 | Crystal structures of the c-di-AMP-synthesizing enzyme CdaA. J.Biol.Chem., 294, 2019
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6HVM
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4JV4
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![BU of 4jv4 by Molmil](/molmil-images/mine/4jv4) | Crystal Structure of RIalpha(91-379) bound to HE33, a N6 di-propyl substituted cAMP analog | 分子名称: | (2R,4aR,6R,7R,7aS)-6-[6-(dipropylamino)-9H-purin-9-yl]tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-oxide, cAMP-dependent protein kinase type I-alpha regulatory subunit | 著者 | Brown, S.H.J, Cheng, C.Y, Saldanha, A.S, Wu, J, Cottam, H, Sankaran, B, Taylor, S.S. | 登録日 | 2013-03-25 | 公開日 | 2013-09-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.952 Å) | 主引用文献 | Implementing Fluorescence Anisotropy Screening and Crystallographic Analysis to Define PKA Isoform-Selective Activation by cAMP Analogs. Acs Chem.Biol., 8, 2013
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4JVA
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![BU of 4jva by Molmil](/molmil-images/mine/4jva) | Crystal Structure of RIIbeta(108-402) bound to HE33, a N6 di-propyl substituted cAMP analog | 分子名称: | (2R,4aR,6R,7R,7aS)-6-[6-(dipropylamino)-9H-purin-9-yl]tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-oxide, cAMP-dependent protein kinase type II-beta regulatory subunit | 著者 | Brown, S.H.J, Cheng, C.Y, Saldanha, A.S, Wu, J, Cottam, H, Sankaran, B, Taylor, S.S. | 登録日 | 2013-03-25 | 公開日 | 2013-09-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Implementing Fluorescence Anisotropy Screening and Crystallographic Analysis to Define PKA Isoform-Selective Activation by cAMP Analogs. Acs Chem.Biol., 8, 2013
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4YUS
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![BU of 4yus by Molmil](/molmil-images/mine/4yus) | Crystal structure of photoactivated adenylyl cyclase of a cyanobacteriaOscillatoria acuminata in hexagonal form | 分子名称: | FLAVIN MONONUCLEOTIDE, Family 3 adenylate cyclase | 著者 | Park, S.-Y, Ohki, M, Sugiyama, K, Kawai, F, Iseki, M. | 登録日 | 2015-03-19 | 公開日 | 2016-06-01 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insight into photoactivation of an adenylate cyclase from a photosynthetic cyanobacterium Proc.Natl.Acad.Sci.USA, 113, 2016
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4YUT
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![BU of 4yut by Molmil](/molmil-images/mine/4yut) | Crystal structure of photoactivated adenylyl cyclase of a cyanobacteriaOscillatoria acuminata in orthorhombic form | 分子名称: | FLAVIN MONONUCLEOTIDE, Family 3 adenylate cyclase | 著者 | Park, S.-Y, Ohki, M, Sugiyama, K, Kawai, F, Iseki, M. | 登録日 | 2015-03-19 | 公開日 | 2016-06-01 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural insight into photoactivation of an adenylate cyclase from a photosynthetic cyanobacterium Proc.Natl.Acad.Sci.USA, 113, 2016
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8GJX
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![BU of 8gjx by Molmil](/molmil-images/mine/8gjx) | Structure of the human STING receptor bound to 2'3'-cUA | 分子名称: | 2'3'-cUA, Stimulator of interferon genes protein | 著者 | Morehouse, B.R, Li, Y, Slavik, K.M, Toyoda, H, Kranzusch, P.J. | 登録日 | 2023-03-16 | 公開日 | 2023-07-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | cGLRs are a diverse family of pattern recognition receptors in innate immunity. Cell, 186, 2023
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8GJZ
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![BU of 8gjz by Molmil](/molmil-images/mine/8gjz) | Structure of a STING receptor from S. pistillata Sp-STING1 bound to 2'3'-cUA | 分子名称: | 2'3'-cUA, Stimulator of interferon genes protein | 著者 | Li, Y, Toyoda, H, Slavik, K.M, Morehouse, B.R, Kranzusch, P.J. | 登録日 | 2023-03-16 | 公開日 | 2023-07-05 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | 主引用文献 | cGLRs are a diverse family of pattern recognition receptors in innate immunity. Cell, 186, 2023
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8GJY
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![BU of 8gjy by Molmil](/molmil-images/mine/8gjy) | Structure of a cGAS-like receptor Sp-cGLR1 from S. pistillata | 分子名称: | cGAS-like receptor 1 | 著者 | Li, Y, Toyoda, H, Slavik, K.M, Morehouse, B.R, Kranzusch, P.J. | 登録日 | 2023-03-16 | 公開日 | 2023-07-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | cGLRs are a diverse family of pattern recognition receptors in innate immunity. Cell, 186, 2023
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8EFN
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![BU of 8efn by Molmil](/molmil-images/mine/8efn) | Structure of Sp-STING3 from Stylophora pistillata coral in complex with 3',3'-cGAMP | 分子名称: | 1,2-ETHANEDIOL, 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, Stimulator of interferon genes protein | 著者 | Li, Y, Slavik, K.M, Morehouse, B.R, Mears, K, Kranzusch, P.J. | 登録日 | 2022-09-08 | 公開日 | 2023-07-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | cGLRs are a diverse family of pattern recognition receptors in innate immunity. Cell, 186, 2023
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8EFM
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![BU of 8efm by Molmil](/molmil-images/mine/8efm) | Structure of coral STING receptor from Stylophora pistillata in complex with 2',3'-cGAMP | 分子名称: | SULFATE ION, Stimulator of interferon genes protein, cGAMP | 著者 | Li, Y, Slavik, K.M, Morehouse, B.R, Mears, K, Kranzusch, P.J. | 登録日 | 2022-09-08 | 公開日 | 2023-07-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | cGLRs are a diverse family of pattern recognition receptors in innate immunity. Cell, 186, 2023
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8GJW
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![BU of 8gjw by Molmil](/molmil-images/mine/8gjw) | Structure of a cGAS-like receptor Cv-cGLR1 from C. virginica | 分子名称: | SULFATE ION, cGAS-like receptor 1 | 著者 | Li, Y, Morehouse, B.R, Slavik, K.M, Liu, J, Toyoda, H, Kranzusch, P.J. | 登録日 | 2023-03-16 | 公開日 | 2023-07-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | cGLRs are a diverse family of pattern recognition receptors in innate immunity. Cell, 186, 2023
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1FX2
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![BU of 1fx2 by Molmil](/molmil-images/mine/1fx2) | |
1FX4
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![BU of 1fx4 by Molmil](/molmil-images/mine/1fx4) | |
7LT1
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![BU of 7lt1 by Molmil](/molmil-images/mine/7lt1) | |
6W10
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![BU of 6w10 by Molmil](/molmil-images/mine/6w10) | |
4W90
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![BU of 4w90 by Molmil](/molmil-images/mine/4w90) | Crystal structure of Bacillus subtilis cyclic-di-AMP riboswitch ydaO | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, MAGNESIUM ION, U1 small nuclear ribonucleoprotein A, ... | 著者 | Jones, C.P, Ferre-D'Amare, A.R. | 登録日 | 2014-08-26 | 公開日 | 2014-10-15 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.118 Å) | 主引用文献 | Crystal structure of a c-di-AMP riboswitch reveals an internally pseudo-dimeric RNA. Embo J., 33, 2014
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3ZBS
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![BU of 3zbs by Molmil](/molmil-images/mine/3zbs) | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation V321A, crystallized with 2'-AMPS | 分子名称: | 2', 3'-CYCLIC NUCLEOTIDE 3'-PHOSPHODIESTERASE, 2'-O-(sulfidophosphinato)adenosine, ... | 著者 | Myllykoski, M, Raasakka, A, Lehtimaki, M, Han, H, Kursula, P. | 登録日 | 2012-11-13 | 公開日 | 2013-07-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Crystallographic Analysis of the Reaction Cycle of 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase, a Unique Member of the 2H Phosphoesterase Family J.Mol.Biol., 425, 2013
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3ZBZ
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![BU of 3zbz by Molmil](/molmil-images/mine/3zbz) | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation V321A, crystallized with 2'-AMPS | 分子名称: | 2', 3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE, 2'-O-(sulfidophosphinato)adenosine, ... | 著者 | Myllykoski, M, Raasakka, A, Lehtimaki, M, Han, H, Kursula, P. | 登録日 | 2012-11-14 | 公開日 | 2013-07-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystallographic Analysis of the Reaction Cycle of 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase, a Unique Member of the 2H Phosphoesterase Family J.Mol.Biol., 425, 2013
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3ZBR
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![BU of 3zbr by Molmil](/molmil-images/mine/3zbr) | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation H230S, crystallized with NADP | 分子名称: | 2', 3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Myllykoski, M, Raasakka, A, Lehtimaki, M, Han, H, Kursula, P. | 登録日 | 2012-11-13 | 公開日 | 2013-07-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.304 Å) | 主引用文献 | Crystallographic Analysis of the Reaction Cycle of 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase, a Unique Member of the 2H Phosphoesterase Family J.Mol.Biol., 425, 2013
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