PDB: 11109 件ウェブページステータス検索Chemie searchBIRD

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5Z5S	Crystal structure of the PPARgamma-LBD complexed with compound 13ab 分子名称: 3-{[6-(4-chloro-3-fluorophenoxy)-1-methyl-1H-benzimidazol-2-yl]methoxy}benzoic acid, CHLORIDE ION, Peptide from Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, ... 著者 Matsui, Y, Hanzawa, H. 登録日 2018-01-19 公開日 2018-10-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Discovery of DS-6930, a potent selective PPAR gamma modulator. Part I: Lead identification. Bioorg. Med. Chem., 26, 2018
2Q7U	Crystal Structure of the F plasmid TraI Relaxase Domain with the Scissile Thymidine Base and Imidodiphosphate 分子名称: IMIDO DIPHOSPHATE, MAGNESIUM ION, Protein traI, ... 著者 Lujan, S.A, Redinbo, M.R. 登録日 2007-06-07 公開日 2008-05-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Disrupting antibiotic resistance propagation by inhibiting the conjugative DNA relaxase. Proc.Natl.Acad.Sci.Usa, 104, 2007
2PIN	Thyroid receptor beta in complex with inhibitor 分子名称: 1-(4-HEXYLPHENYL)PROP-2-EN-1-ONE, SULFATE ION, Thyroid hormone receptor beta-1, ... 著者 Estebanez-Perpina, E, Jouravel, N, Baxter, J.D, Guy, L.R, Webb, P, Fletterick, R.J. 登録日 2007-04-13 公開日 2008-02-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural insight into the mode of action of a direct inhibitor of coregulator binding to the thyroid hormone receptor. Mol.Endocrinol., 21, 2007
5ZDK	Crystal Structure Analysis of TtQRS in complex with ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CESIUM ION, CHLORIDE ION, ... 著者 Mutharasappan, N, Jain, V, Sharma, A, Manickam, Y, Jeyaraman, J. 登録日 2018-02-23 公開日 2018-12-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structural and functional analysis of Glutaminyl-tRNA synthetase (TtGlnRS) from Thermus thermophilus HB8 and its complexes Int. J. Biol. Macromol., 120, 2018
5WT2	NifS from Helicobacter pylori 分子名称: CHLORIDE ION, Cysteine desulfurase IscS, ISOPROPYL ALCOHOL, ... 著者 Fujishiro, T, Takahashi, Y. 登録日 2016-12-09 公開日 2017-12-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.301 Å) 主引用文献 Snapshots of PLP-substrate and PLP-product external aldimines as intermediates in two types of cysteine desulfurase enzymes. Febs J., 2019
2QSY	Human nicotinamide riboside kinase 1 in complex with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Nicotinamide riboside kinase 1, ... 著者 Rabeh, W.M, Tempel, W, Nedyalkova, L, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Brenner, C, Park, H, Structural Genomics Consortium (SGC) 登録日 2007-07-31 公開日 2007-08-14 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD(+). Plos Biol., 5, 2007
5WJK	2.0-Angstrom In situ Mylar structure of sperm whale myoglobin (SWMb) at 293 K 分子名称: CHLORIDE ION, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Broecker, J, Ou, W.-L, Ernst, O.P. 登録日 2017-07-23 公開日 2017-12-13 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 High-throughput in situ X-ray screening of and data collection from protein crystals at room temperature and under cryogenic conditions. Nat Protoc, 13, 2018
4CBE	Crystal structure of complement factors H and FHL-1 binding protein BBH06 or CRASP-2 from Borrelia burgdorferi (Native) 分子名称: COMPLEMENT REGULATOR-ACQUIRING SURFACE PROTEIN 2 (CRASP-2) 著者 Brangulis, K, Petrovskis, I, Kazaks, A, Ranka, R, Tars, K. 登録日 2013-10-13 公開日 2014-04-16 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Structural Characterization of Cspz, a Complement Regulator Factor H and Fhl-1 Binding Protein from Borrelia Burgdorferi. FEBS J., 281, 2014
5ZH3	CRYSTAL STRUCTURE OF PfKRS WITH INHIBITOR CLADO-6 分子名称: (3S)-6,8-dihydroxy-3-{[(2R,6R)-6-methyloxan-2-yl]methyl}-3,4-dihydro-1H-2-benzopyran-1-one, LYSINE, Lysine-tRNA ligase 著者 Babbar, P, Malhotra, N, Sharma, M, Harlos, K, Reddy, D.S, Manickam, Y, Sharma, A. 登録日 2018-03-11 公開日 2018-06-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite J. Med. Chem., 61, 2018
5XXP	Crystal structure of CbnR_DBD-DNA complex 分子名称: DNA (25-MER), LysR-type regulatory protein 著者 Senda, T, Senda, M. 登録日 2017-07-04 公開日 2018-01-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Crystal structure of the DNA-binding domain of the LysR-type transcriptional regulator CbnR in complex with a DNA fragment of the recognition-binding site in the promoter region FEBS J., 285, 2018
5XM0	The mouse nucleosome structure containing H2A, H2B type3-A, H3.3, and H4 分子名称: DNA (146-MER), Histone H2A type 1-B, Histone H2B type 3-A, ... 著者 Taguchi, H, Horikoshi, N, Kurumizaka, H. 登録日 2017-05-12 公開日 2018-03-07 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.874 Å) 主引用文献 Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration. Nat Commun, 9, 2018
2QSZ	Human nicotinamide riboside kinase 1 in complex with nicotinamide mononucleotide 分子名称: BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, CHLORIDE ION, Nicotinamide riboside kinase 1, ... 著者 Rabeh, W.M, Tempel, W, Nedyalkova, L, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Brenner, C, Park, H, Structural Genomics Consortium (SGC) 登録日 2007-07-31 公開日 2007-08-14 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD(+). Plos Biol., 5, 2007
5Z6S	Crystal structure of the PPARgamma-LBD complexed with compound DS-6930 分子名称: 3-[[6-(3,5-dimethylpyridin-2-yl)oxy-1-methyl-benzimidazol-2-yl]methoxy]benzoic acid, CHLORIDE ION, Peptide from Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, ... 著者 Matsui, Y, Hanzawa, H. 登録日 2018-01-25 公開日 2018-10-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Discovery of DS-6930, a potent selective PPAR gamma modulator. Part II: Lead optimization. Bioorg. Med. Chem., 26, 2018
5ZDO	Crystal Structure Analysis of TtQRS in co-crystallised with ATP 分子名称: CHLORIDE ION, Glutamine-tRNA ligase 著者 Mutharasappan, N, Jain, V, Sharma, A, Manickam, Y, Jeyaraman, J. 登録日 2018-02-23 公開日 2018-12-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural and functional analysis of Glutaminyl-tRNA synthetase (TtGlnRS) from Thermus thermophilus HB8 and its complexes Int. J. Biol. Macromol., 120, 2018
5ZH5	CRYSTAL STRUCTURE OF PfKRS WITH INHIBITOR CLADO-2 分子名称: (3S)-6,8-dihydroxy-3-{[(2R,6S)-6-methyloxan-2-yl]methyl}-3,4-dihydro-1H-2-benzopyran-1-one, CHLORIDE ION, LYSINE, ... 著者 Babbar, P, Malhotra, N, Sharma, M, Harlos, K, Reddy, D.S, Manickam, Y, Sharma, A. 登録日 2018-03-11 公開日 2018-06-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.08 Å) 主引用文献 Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite J. Med. Chem., 61, 2018
2QT0	Human nicotinamide riboside kinase 1 in complex with nicotinamide riboside and an ATP analogue 分子名称: MAGNESIUM ION, Nicotinamide riboside, Nicotinamide riboside kinase 1, ... 著者 Rabeh, W.M, Tempel, W, Nedyalkova, L, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Brenner, C, Park, H, Structural Genomics Consortium (SGC) 登録日 2007-07-31 公開日 2007-08-14 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD(+). Plos Biol., 5, 2007
2QT1	Human nicotinamide riboside kinase 1 in complex with nicotinamide riboside 分子名称: Nicotinamide riboside, Nicotinamide riboside kinase 1, PHOSPHATE ION, ... 著者 Rabeh, W.M, Tempel, W, Nedyalkova, L, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Brenner, C, Park, H, Structural Genomics Consortium (SGC) 登録日 2007-07-31 公開日 2007-08-14 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD(+). Plos Biol., 5, 2007
2P23	Crystal structure of human FGF19 分子名称: Fibroblast growth factor 19 著者 Mohammadi, M. 登録日 2007-03-06 公開日 2007-04-10 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members. Mol.Cell.Biol., 27, 2007
2P0E	Human nicotinamide riboside kinase 1 in complex with tiazofurin 分子名称: (1R)-1-[4-(AMINOCARBONYL)-1,3-THIAZOL-2-YL]-1,4-ANHYDRO-D-RIBITOL, CHLORIDE ION, Nicotinamide riboside kinase 1, ... 著者 Rabeh, W.M, Tempel, W, Nedyalkova, L, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Brenner, C, Park, H, Structural Genomics Consortium (SGC) 登録日 2007-02-28 公開日 2007-05-08 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD(+). Plos Biol., 5, 2007
7BTX	The mitochondrial SAM-Mdm10 supercomplex in GDN micelle from S.cere 分子名称: MDM10 isoform 1, Mitochondrial outer membrane beta-barrel protein, Sorting assembly machinery 35 kDa subunit, ... 著者 Takeda, H, Tsutsumi, A, Nishizawa, T, Nureki, O, Kikkawa, M, Endo, T. 登録日 2020-04-03 公開日 2021-01-20 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Mitochondrial sorting and assembly machinery operates by beta-barrel switching. Nature, 590, 2021
7BY6	Plasmodium vivax cytoplasmic Phenylalanyl-tRNA synthetase in complex with BRD1389 分子名称: (3S,4R,8R,9R,10S)-N-(4-cyclopropyloxyphenyl)-10-(methoxymethyl)-3,4-bis(oxidanyl)-9-[4-(2-phenylethynyl)phenyl]-1,6-diazabicyclo[6.2.0]decane-6-carboxamide, MAGNESIUM ION, Phenylalanyl-tRNA synthetase beta chain, ... 著者 Malhotra, N, Manmohan, S, Harlos, K, Melillo, B, Schreiber, S.L, Manickam, Y, Sharma, S. 登録日 2020-04-21 公開日 2020-11-04 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.997 Å) 主引用文献 Structural basis of malaria parasite phenylalanine tRNA-synthetase inhibition by bicyclic azetidines. Nat Commun, 12, 2021
7BRU	Crystal structure of human RTN3 LIR fused to human GABARAP 分子名称: PHOSPHATE ION, Reticulon-3,Gamma-aminobutyric acid receptor-associated protein 著者 Yamasaki, A, Noda, N.N. 登録日 2020-03-30 公開日 2020-07-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.149 Å) 主引用文献 Super-assembly of ER-phagy receptor Atg40 induces local ER remodeling at contacts with forming autophagosomal membranes. Nat Commun, 11, 2020
7BTY	The mitochondrial SAM-Mdm10 supercomplex in Nanodisc from S.cere 分子名称: MDM10 isoform 1, Mitochondrial outer membrane beta-barrel protein, Sorting assembly machinery 35 kDa subunit, ... 著者 Takeda, H, Tsutsumi, A, Nishizawa, T, Nureki, O, Kikkawa, M, Endo, T. 登録日 2020-04-03 公開日 2021-01-20 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Mitochondrial sorting and assembly machinery operates by beta-barrel switching. Nature, 590, 2021
7CID	Crystal structure of P.aeruginosa LpxC in complex with inhibitor 分子名称: 1-[3-(4-chlorophenyl)propyl]imidazole, DIMETHYL SULFOXIDE, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ... 著者 Baker, L.M, Mima, M, Surgenor, A, Robertson, A. 登録日 2020-07-07 公開日 2020-12-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Fragment-Based Discovery of Novel Non-Hydroxamate LpxC Inhibitors with Antibacterial Activity. J.Med.Chem., 63, 2020
7CI4	Crystal structure of P.aeruginosa LpxC in complex with inhibitor 分子名称: (2R)-2-azanyl-4-methylsulfonyl-N-[3-(trifluoromethyloxy)phenyl]butanamide, CHLORIDE ION, MAGNESIUM ION, ... 著者 Mima, M, Baker, L.M, Surgenor, A, Robertson, A. 登録日 2020-07-07 公開日 2020-12-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Fragment-Based Discovery of Novel Non-Hydroxamate LpxC Inhibitors with Antibacterial Activity. J.Med.Chem., 63, 2020

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