2LF1
| Solution structure of L. casei dihydrofolate reductase complexed with NADPH, 30 structures | 分子名称: | Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Polshakov, V, Feeney, J, Birdsall, B, Kovalevskaya, N. | 登録日 | 2011-06-28 | 公開日 | 2011-12-21 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structures of apo L. casei dihydrofolate reductase and its complexes with trimethoprim and NADPH: contributions to positive cooperative binding from ligand-induced refolding, conformational changes, and interligand hydrophobic interactions Biochemistry, 50, 2011
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6NCI
| Crystal structure of CDP-Chase: Vector data collection | 分子名称: | D-ribose, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ... | 著者 | Miller, M.S, Shi, W, Gabelli, S.B. | 登録日 | 2018-12-11 | 公開日 | 2019-02-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Getting the Most Out of Your Crystals: Data Collection at the New High-Flux, Microfocus MX Beamlines at NSLS-II. Molecules, 24, 2019
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1B9Z
| BACILLUS CEREUS BETA-AMYLASE COMPLEXED WITH MALTOSE | 分子名称: | ACETATE ION, CALCIUM ION, PROTEIN (BETA-AMYLASE), ... | 著者 | Mikami, B, Adachi, M, Kage, T, Sarikaya, E, Nanmori, T, Shinke, R, Utsumi, S. | 登録日 | 1999-03-06 | 公開日 | 1999-03-15 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of raw starch-digesting Bacillus cereus beta-amylase complexed with maltose. Biochemistry, 38, 1999
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4OSN
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2FY9
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1X4U
| Solution structure of the FYVE domain from human FYVE domain containing 27 isoform b protein | 分子名称: | ZINC ION, Zinc finger, FYVE domain containing 27 isoform b | 著者 | Tomizawa, T, Kigawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-05-15 | 公開日 | 2005-11-15 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the FYVE domain from human FYVE domain containing 27 isoform b protein To be Published
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3LC9
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4MY6
| EnaH-EVH1 in complex with peptidomimetic low-molecular weight inhibitor Ac-[2-Cl-F]-[ProM-2]-[ProM-1]-OH | 分子名称: | (3aR,5aS,8S,10aS)-1-[(3S,6R,8aS)-1'-[(2S)-2-acetamido-3-(2-chlorophenyl)propanoyl]-5-oxidanylidene-spiro[1,2,3,8a-tetrahydroindolizine-6,2'-pyrrolidine]-3-yl]carbonyl-10-oxidanylidene-2,3,3a,5a,8,10a-hexahydrodipyrrolo[3,2-b:3',1'-f]azepine-8-carboxylic acid, BROMIDE ION, Protein enabled homolog | 著者 | Barone, M, Roske, Y, Kuehne, R. | 登録日 | 2013-09-27 | 公開日 | 2014-10-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | A modular toolkit to inhibit proline-rich motif-mediated protein-protein interactions. Proc.Natl.Acad.Sci.USA, 112, 2015
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1A3F
| PHOSPHOLIPASE A2 (PLA2) FROM NAJA NAJA VENOM | 分子名称: | PHOSPHOLIPASE A2 | 著者 | Segelke, B.W, Nguyen, D, Chee, R, Xuong, H.N, Dennis, E.A. | 登録日 | 1998-01-21 | 公開日 | 1998-04-29 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structures of two novel crystal forms of Naja naja naja phospholipase A2 lacking Ca2+ reveal trimeric packing. J.Mol.Biol., 279, 1998
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5Z1E
| MAP2K7 C218S mutant-inhibitor | 分子名称: | Dual specificity mitogen-activated protein kinase kinase 7, N-[3-(6-methyl-1H-indazol-3-yl)phenyl]prop-2-enamide | 著者 | Kinoshita, T, London, N. | 登録日 | 2017-12-26 | 公開日 | 2019-01-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Covalent Docking Identifies a Potent and Selective MKK7 Inhibitor. Cell Chem Biol, 26, 2019
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5ZA8
| uPA-BB2-27F | 分子名称: | 3-azanyl-5-(azepan-1-yl)-N-carbamimidoyl-6-(1-methylpyrazol-4-yl)pyrazine-2-carboxamide, Urokinase-type plasminogen activator chain B | 著者 | Buckley, B.J, Jiang, L.G, Huang, M.D, Kelso, M.J, Ranson, M. | 登録日 | 2018-02-06 | 公開日 | 2018-12-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | 6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer. J. Med. Chem., 61, 2018
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5ZAF
| uPA-BB2-28F | 分子名称: | 3-azanyl-5-(azepan-1-yl)-N-carbamimidoyl-6-(furan-3-yl)pyrazine-2-carboxamide, Urokinase-type plasminogen activator chain B | 著者 | Buckley, B.J, Jiang, L.G, Huang, M.D, Kelso, M.J, Ranson, M. | 登録日 | 2018-02-07 | 公開日 | 2018-12-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | 6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer. J. Med. Chem., 61, 2018
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2K4K
| Solution structure of GSP13 from Bacillus subtilis | 分子名称: | General stress protein 13 | 著者 | Yu, W, Yu, B, Hu, J, Jin, C, Xia, B. | 登録日 | 2008-06-13 | 公開日 | 2009-05-12 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of GSP13 from Bacillus subtilis exhibits an S1 domain related to cold shock proteins. J.Biomol.Nmr, 43, 2009
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3NEW
| p38-alpha complexed with Compound 10 | 分子名称: | 4-(trifluoromethyl)-3-[3-(trifluoromethyl)phenyl]-1,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one, Mitogen-activated protein kinase 14 | 著者 | Goedken, E.R, Comess, K.M, Sun, C, Argiriadi, M, Jia, Y, Quinn, C.M, Banach, D.L, Marcotte, D, Borhani, D. | 登録日 | 2010-06-09 | 公開日 | 2010-12-01 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Discovery and Characterization of Non-ATP Site Inhibitors of the Mitogen Activated Protein (MAP) Kinases. Acs Chem.Biol., 6, 2011
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3NGU
| Structure of Leishmania NDKb complexed with ADP. | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Nucleoside diphosphate kinase | 著者 | Trindade, D.M, Sousa, T.A.C.B, Tonoli, C.C.C, Santos, C.R, Arni, R.K, Ward, R.J, Oliveira, A.H.C, Murakami, M.T. | 登録日 | 2010-06-13 | 公開日 | 2011-04-27 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Molecular adaptability of nucleoside diphosphate kinase b from trypanosomatid parasites: stability, oligomerization and structural determinants of nucleotide binding. Mol Biosyst, 7, 2011
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3N50
| Human Early B-cell factor 3 (EBF3) IPT/TIG and HLHLH domains | 分子名称: | Transcription factor COE3 | 著者 | Lehtio, L, Siponen, M.I, Arrowsmith, C.H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Schuler, H, Schutz, P, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Wisniewska, M, Berglund, H, Structural Genomics Consortium (SGC) | 登録日 | 2010-05-24 | 公開日 | 2010-06-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.102 Å) | 主引用文献 | Structural Determination of Functional Domains in Early B-cell Factor (EBF) Family of Transcription Factors Reveals Similarities to Rel DNA-binding Proteins and a Novel Dimerization Motif. J.Biol.Chem., 285, 2010
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1RDT
| Crystal Structure of a new rexinoid bound to the RXRalpha ligand binding doamin in the RXRalpha/PPARgamma heterodimer | 分子名称: | (S)-(2E)-3[4-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-2-NAPHTHALENYL)TETRAHYDRO-1-BENZOFURAN-2-YL]-2-PROPENOIC ACID, 2-(2-BENZOYL-PHENYLAMINO)-3-{4-[2-(5-METHYL-2-PHENYL-OXAZOL-4-YL)-ETHOXY]-PHENYL}-PROPIONIC ACID, LxxLL motif coactivator, ... | 著者 | Haffner, C.D, Lenhard, J.M, Miller, A.B, McDougald, D.L, Dwornik, K, Ittoop, O.R, Gampe Jr, R.T, Xu, H.E, Blanchard, S, Montana, V.G. | 登録日 | 2003-11-06 | 公開日 | 2004-11-09 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure-based design of potent retinoid X receptor alpha agonists. J.Med.Chem., 47, 2004
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5Z1D
| MAP2K7 C276S mutant-inhibitor | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Dual specificity mitogen-activated protein kinase kinase 7, N-[3-(6-methyl-1H-indazol-3-yl)phenyl]prop-2-enamide | 著者 | Kinoshita, T, London, N. | 登録日 | 2017-12-26 | 公開日 | 2019-01-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Covalent Docking Identifies a Potent and Selective MKK7 Inhibitor. Cell Chem Biol, 26, 2019
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2LTQ
| High resolution structure of DsbB C41S by joint calculation with solid-state NMR and X-ray data | 分子名称: | Disulfide bond formation protein B, Fab fragment heavy chain, Fab fragment light chain, ... | 著者 | Tang, M, Sperling, L.J, Schwieters, C.D, Nesbitt, A.E, Gennis, R.B, Rienstra, C.M. | 登録日 | 2012-05-30 | 公開日 | 2013-02-27 | 最終更新日 | 2023-06-14 | 実験手法 | SOLID-STATE NMR | 主引用文献 | Structure of the Disulfide Bond Generating Membrane Protein DsbB in the Lipid Bilayer. J.Mol.Biol., 425, 2013
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4OOX
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2FF7
| The ABC-ATPase of the ABC-transporter HlyB in the ADP bound state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Alpha-hemolysin translocation ATP-binding protein hlyB | 著者 | Zaitseva, J, Oswald, C, Jumpertz, T, Jenewein, S, Holland, I.B, Schmitt, L. | 登録日 | 2005-12-19 | 公開日 | 2006-08-08 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | A structural analysis of asymmetry required for catalytic activity of an ABC-ATPase domain dimer. Embo J., 25, 2006
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1SSU
| Structural and biochemical evidence for disulfide bond heterogeneity in active forms of the somatomedin B domain of human vitronectin | 分子名称: | Vitronectin | 著者 | Kamikubo, Y, De Guzman, R, Kroon, G, Curriden, S, Neels, J.G, Churchill, M.J, Dawson, P, Oldziej, S, Jagielska, A, Scheraga, H.A, Loskutoff, D.J, Dyson, H.J. | 登録日 | 2004-03-24 | 公開日 | 2004-07-27 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Disulfide bonding arrangements in active forms of the somatomedin B domain of human vitronectin. Biochemistry, 43, 2004
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3Q36
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2YYY
| Crystal structure of Glyceraldehyde-3-phosphate dehydrogenase | 分子名称: | Glyceraldehyde-3-phosphate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Malay, A.D, Bessho, Y, Padmanabhan, B, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-05-02 | 公開日 | 2007-11-06 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structure of glyceraldehyde-3-phosphate dehydrogenase from the archaeal hyperthermophile Methanocaldococcus jannaschii. Acta Crystallogr.,Sect.F, 65, 2009
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5RT7
| PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with ZINC000015442276 | 分子名称: | 1H-PYRROLO[2,3-B]PYRIDINE, Non-structural protein 3 | 著者 | Correy, G.J, Young, I.D, Thompson, M.C, Fraser, J.S. | 登録日 | 2020-09-28 | 公開日 | 2020-12-16 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking. Sci Adv, 7, 2021
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