5XJC
| Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstrom | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Zhang, X, Yan, C, Hang, J, Finci, I.L, Lei, J, Shi, Y. | 登録日 | 2017-04-30 | 公開日 | 2017-07-05 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | An Atomic Structure of the Human Spliceosome Cell, 169, 2017
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2R03
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2R05
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1W6R
| Complex of TcAChE with galanthamine derivative | 分子名称: | (-)-GALANTHAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, ... | 著者 | Greenblatt, H.M, Guillou, C, Guenard, D, Badet, B, Thal, C, Silman, I, Sussman, J.L. | 登録日 | 2004-08-23 | 公開日 | 2004-11-25 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | The complex of a bivalent derivative of galanthamine with torpedo acetylcholinesterase displays drastic deformation of the active-site gorge: implications for structure-based drug design. J.Am.Chem.Soc., 126, 2004
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1W75
| Native Orthorhombic form of Torpedo californica acetylcholinesterase (AChE) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE | 著者 | Greenblatt, H.M, Botti, S, Argaman, A, Silman, I, Sussman, J.L. | 登録日 | 2004-08-29 | 公開日 | 2004-11-25 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The complex of a bivalent derivative of galanthamine with torpedo acetylcholinesterase displays drastic deformation of the active-site gorge: implications for structure-based drug design. J.Am.Chem.Soc., 126, 2004
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2R02
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2BKI
| Myosin VI nucleotide-free (MDinsert2-IQ) crystal structure | 分子名称: | CALCIUM ION, CALMODULIN, SULFATE ION, ... | 著者 | Menetrey, J, Bahloul, A, Yengo, C, Wells, A, Morris, C, Sweeney, H.L, Houdusse, A. | 登録日 | 2005-02-16 | 公開日 | 2005-06-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | The Structure of the Myosin Vi Motor Reveals the Mechanism of Directionality Reversal Nature, 435, 2005
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1WA7
| SH3 DOMAIN OF HUMAN LYN TYROSINE KINASE IN COMPLEX WITH A HERPESVIRAL LIGAND | 分子名称: | HYPOTHETICAL 28.7 KDA PROTEIN IN DHFR 3'REGION (ORF1), TYROSINE-PROTEIN KINASE LYN | 著者 | Bauer, F, Schweimer, K, Hoffmann, S, Roesch, P, Sticht, H. | 登録日 | 2004-10-25 | 公開日 | 2005-07-07 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Investigation of the Binding of a Herpesviral Protein to the SH3 Domain of Tyrosine Kinase Lck. Biochemistry, 41, 2002
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2E1Y
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2E20
| Crystal structure of Salmonella typhimurium propionate kinase (TdcD) in complex with diadenosine tetraphosphate (Ap4A) | 分子名称: | 1,2-ETHANEDIOL, BIS(ADENOSINE)-5'-TETRAPHOSPHATE, Propionate Kinase | 著者 | Simanshu, D.K, Savithri, H.S, Murthy, M.R.N. | 登録日 | 2006-11-04 | 公開日 | 2007-09-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structures of Salmonella typhimurium propionate kinase and its complex with Ap4A: evidence for a novel Ap4A synthetic activity. Proteins, 70, 2008
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2B0H
| Solution structure of VBS3 fragment of talin | 分子名称: | Talin-1 | 著者 | Gingras, A.R, Vogel, K.P, Steinhoff, H.J, Ziegler, W.H, Patel, B, Emsley, J, Critchley, D.R, Roberts, G.C, Barsukov, I.L. | 登録日 | 2005-09-14 | 公開日 | 2006-01-17 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and Dynamic Characterization of a Vinculin Binding Site in the Talin Rod Biochemistry, 45, 2006
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2D10
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2E1Z
| Crystal structure of Salmonella typhimurium propionate kinase (TdcD) in complex with diadenosine tetraphosphate (Ap4A) obtained after co-crystallization with ATP | 分子名称: | 1,2-ETHANEDIOL, BIS(ADENOSINE)-5'-TETRAPHOSPHATE, Propionate Kinase | 著者 | Simanshu, D.K, Savithri, H.S, Murthy, M.R.N. | 登録日 | 2006-11-04 | 公開日 | 2007-09-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Crystal structures of Salmonella typhimurium propionate kinase and its complex with Ap4A: evidence for a novel Ap4A synthetic activity. Proteins, 70, 2008
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6EM3
| State A architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | 分子名称: | 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ... | 著者 | Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R. | 登録日 | 2017-10-01 | 公開日 | 2017-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes. Cell, 171, 2017
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6EM1
| State C (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | 分子名称: | 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ... | 著者 | Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R. | 登録日 | 2017-10-01 | 公開日 | 2017-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes. Cell, 171, 2017
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2Q21
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5Z3G
| Cryo-EM structure of a nucleolar pre-60S ribosome (Rpf1-TAP) | 分子名称: | 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... | 著者 | Zhu, X, Zhou, D, Ye, K. | 登録日 | 2018-01-06 | 公開日 | 2018-04-11 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | 主引用文献 | Cryo-EM structure of an early precursor of large ribosomal subunit reveals a half-assembled intermediate. Protein Cell, 10, 2019
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3SQD
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8IR3
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8IPY
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8IPX
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2FPF
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7DBP
| Linker histone defines structure and self-association behaviour of the 177 bp human chromosome | 分子名称: | DNA (175-MER), Histone H1.0, Histone H2A type 1-B/E, ... | 著者 | Wang, S, Vogirala, K.V, Soman, A, Liu, Z.B. | 登録日 | 2020-10-21 | 公開日 | 2020-12-23 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Linker histone defines structure and self-association behaviour of the 177 bp human chromatosome. Sci Rep, 11, 2021
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6ICZ
| Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstrom | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | 著者 | Zhang, X, Zhan, X, Yan, C, Shi, Y. | 登録日 | 2018-09-07 | 公開日 | 2019-03-13 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
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2H3G
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