PDB: 245011 件ウェブページステータス検索Chemie searchBIRD

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7MZI	SARS-CoV-2 receptor binding domain bound to Fab WCSL 129 分子名称: GLYCEROL, Spike protein S1, TETRAETHYLENE GLYCOL, ... 著者 Pymm, P, Tan, L.L, Dietrich, M.H, Chan, L.J, Tham, W.H. 登録日 2021-05-24 公開日 2021-10-06 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain. Cell Rep, 37, 2021
7NHG	Crystal structure of the human METTL3-METTL14 complex with compound ASI_M3M_041 分子名称: ACETATE ION, N-[[(3R)-3-Hydroxy-1-[6-(methylamino)pyrimidin-4-yl]piperidin-3-yl]methyl]-4-(piperidin-1-ylmethyl)benzamide, N6-adenosine-methyltransferase catalytic subunit, ... 著者 Bedi, R.K, Huang, D, Caflisch, A. 登録日 2021-02-10 公開日 2021-10-20 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3 Acs Bio Med Chem Au, 2023
6WZM	LY3041658 Fab bound to CXCL8 分子名称: 1,2-ETHANEDIOL, Interleukin-8, LY3041658 Fab heavy chain, ... 著者 Durbin, J.D, Druzina, Z. 登録日 2020-05-14 公開日 2020-11-25 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Discovery and characterization of a neutralizing pan-ELR+CXC chemokine monoclonal antibody. Mabs, 12
7NHV	Crystal structure of the human METTL3-METTL14 complex with compound UOZ016 分子名称: (R)-N-((1-(6-(benzylamino)pyrimidin-4-yl)-3-hydroxypiperidin-3-yl)methyl)-4-((4,4-dimethylpiperidin-1-yl)methyl)benzamide, ACETATE ION, N6-adenosine-methyltransferase catalytic subunit, ... 著者 Bedi, R.K, Huang, D, Caflisch, A. 登録日 2021-02-11 公開日 2021-10-20 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3 Acs Bio Med Chem Au, 2023
7NHH	Crystal structure of the human METTL3-METTL14 complex with compound UOZ002 分子名称: (R)-N-((3-hydroxy-1-(6-(methylamino)pyrimidin-4-yl)piperidin-3-yl)methyl)-4-((4-methylpiperidin-1-yl)methyl)benzamide, ACETATE ION, MAGNESIUM ION, ... 著者 Bedi, R.K, Huang, D, Caflisch, A. 登録日 2021-02-10 公開日 2021-10-20 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3 Acs Bio Med Chem Au, 2023
7NI7	Crystal structure of the human METTL3-METTL14 complex with compound UOZ031 分子名称: (R)-4-((4,4-dimethylpiperidin-1-yl)methyl)-2-hydroxy-N-((3-hydroxy-1-(6-((3-(methylcarbamoyl)benzyl)amino)pyrimidin-4-yl)piperidin-3-yl)methyl)benzamide, ACETATE ION, MAGNESIUM ION, ... 著者 Bedi, R.K, Huang, D, Caflisch, A. 登録日 2021-02-11 公開日 2021-10-20 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3 Acs Bio Med Chem Au, 2023
4WIQ	The structure of Murine alpha-Dystroglycan T190M mutant N-terminal domain. 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Dystroglycan 著者 Brancaccio, A, Lamba, D, Cassetta, A, Bozzi, M, Covaceuszach, S, Sciandra, F, Bigotti, M.G. 登録日 2014-09-26 公開日 2015-05-13 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 The Structure of the T190M Mutant of Murine alpha-Dystroglycan at High Resolution: Insight into the Molecular Basis of a Primary Dystroglycanopathy. Plos One, 10, 2015
184D	SELF-ASSOCIATION OF A DNA LOOP CREATES A QUADRUPLEX: CRYSTAL STRUCTURE OF D(GCATGCT) AT 1.8 ANGSTROMS RESOLUTION 分子名称: DNA (5'-D(*GP*CP*AP*TP*GP*CP*T)-3'), MAGNESIUM ION 著者 Leonard, G.A, Zhang, S, Peterson, M.R, Harrop, S.J, Helliwell, J.R, Cruse, W.B.T, Langlois D'Estaintot, B, Kennard, O, Brown, T, Hunter, W.N. 登録日 1994-08-10 公開日 1995-07-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Self-association of a DNA loop creates a quadruplex: crystal structure of d(GCATGCT) at 1.8 A resolution. Structure, 3, 1995
7NL7	Crystal Structure of DC-SIGN in complex with a triazole-based glycomimetic ligand 分子名称: 3-Aminopropyl 2-deoxy-2-(4-phenyl-1,2,3-triazol-1-yl)-alpha-D-mannopyranoside, CALCIUM ION, DC-SIGN, ... 著者 Jakob, R.P, Cramer, J, Lakkaichi, A, Aliu, B, Cattaneo, I, Klein, S, Jiang, X, Rabbani, S, Schwardt, O, Ernst, B, Maier, T. 登録日 2021-02-22 公開日 2021-10-27 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Sweet Drugs for Bad Bugs: A Glycomimetic Strategy against the DC-SIGN-Mediated Dissemination of SARS-CoV-2. J.Am.Chem.Soc., 143, 2021
4X91	Crystal structure of Lysosomal Phospholipase A2 in complex with Isopropyl dodec-11-enylfluorophosphonate (IDFP) 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Glukhova, A, Tesmer, J.J.G. 登録日 2014-12-11 公開日 2015-03-11 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure and function of lysosomal phospholipase A2 and lecithin:cholesterol acyltransferase. Nat Commun, 6, 2015
7NL6	Crystal Structure of DC-SIGN in complex with a triazole-based glycomimetic ligand 分子名称: CALCIUM ION, DC-SIGN, CRD domain, ... 著者 Jakob, R.P, Cramer, J, Lakkaichi, A, Aliu, B, Cattaneo, I, Klein, S, Jiang, X, Rabbani, S, Schwardt, O, Ernst, B, Maier, T. 登録日 2021-02-22 公開日 2021-10-27 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Sweet Drugs for Bad Bugs: A Glycomimetic Strategy against the DC-SIGN-Mediated Dissemination of SARS-CoV-2. J.Am.Chem.Soc., 143, 2021
4WF1	Crystal structure of the E. coli ribosome bound to negamycin. 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Olivier, N.B, Altman, R.B, Noeske, J, Basarab, G.S, Code, E, Ferguson, A.D, Gao, N, Huang, J, Juette, M.F, Livchak, S, Miller, M.D, Prince, D.B, Cate, J.H.D, Buurman, E.T, Blanchard, S.C. 登録日 2014-09-11 公開日 2014-11-05 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (3.09 Å) 主引用文献 Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome. Proc.Natl.Acad.Sci.USA, 111, 2014
7NL4	OsNIP2;1 silicon transporter from rice 分子名称: Aquaporin NIP2-1, CADMIUM ION 著者 van den Berg, B. 登録日 2021-02-22 公開日 2021-11-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural Basis for Silicic Acid Uptake by Higher Plants. J.Mol.Biol., 433, 2021
7OY5	Crystal structure of GSK3Beta in complex with ARN25068 分子名称: CHLORIDE ION, Glycogen synthase kinase-3 beta, ~{N}4-(3-cyclopropyl-1~{H}-pyrazol-5-yl)-~{N}2-(phenylmethyl)thieno[3,2-d]pyrimidine-2,4-diamine 著者 Tripathi, S.K, Balboni, B, Demuro, S, DiMartino, R, Giabbai, B, Storici, P, Ortega, J, Girotto, S, Cavalli, A. 登録日 2021-06-23 公開日 2022-03-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 ARN25068, a versatile starting point towards triple GSK-3 beta /FYN/DYRK1A inhibitors to tackle tau-related neurological disorders. Eur.J.Med.Chem., 229, 2022
4WT2	Co-crystal Structure of MDM2 in Complex with AM-7209 分子名称: 4-({[(3R,5R,6S)-1-[(1S)-2-(tert-butylsulfonyl)-1-cyclopropylethyl]-6-(4-chloro-3-fluorophenyl)-5-(3-chlorophenyl)-3-methyl-2-oxopiperidin-3-yl]acetyl}amino)-2-methoxybenzoic acid, E3 ubiquitin-protein ligase Mdm2, SULFATE ION 著者 Shaffer, P.L, Huang, X, Yakowec, P, Long, A.M. 登録日 2014-10-30 公開日 2014-12-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Discovery of AM-7209, a Potent and Selective 4-Amidobenzoic Acid Inhibitor of the MDM2-p53 Interaction. J.Med.Chem., 57, 2014
8YU4	Structure of cyclohexanone monooxygenase mutant from Acinetobacter calcoaceticus 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, Putative flavin-binding monooxygenase 著者 Qiang, G, Zheng, Y.C, Feng, L, Yu, H.L. 登録日 2024-03-26 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Loop Engineering Facilitates the Nicotinamide Cofactors Utilization of BVMOs To Be Published
8G20	Crystal Structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with inhibitor Mz327 分子名称: 1,2-ETHANEDIOL, 4-[(N-butylpentanamido)methyl]-N-hydroxybenzamide, ETHANOL, ... 著者 Tararina, M.A, Christianson, D.W. 登録日 2023-02-03 公開日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.766 Å) 主引用文献 Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation. J.Med.Chem., 66, 2023
4X55	Structure of the class D Beta-Lactamase OXA-225 K82D in Acyl-Enzyme Complex with Ceftazidime 分子名称: 1-({(2R)-2-[(1R)-1-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-2-oxoethyl]-4-carboxy-3,6-dihydro-2H-1,3-thiazin-5-yl}methyl)pyridinium, Beta-lactamase OXA-225 著者 Clasman, J.R, June, C.M, Powers, R.A, Leonard, D.A. 登録日 2014-12-04 公開日 2015-03-11 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.941 Å) 主引用文献 Structural Basis of Activity against Aztreonam and Extended Spectrum Cephalosporins for Two Carbapenem-Hydrolyzing Class D beta-Lactamases from Acinetobacter baumannii. Biochemistry, 54, 2015
4P3U	Crystal structure of the bacterial A1408U-mutant ribosomal decoding site (C2 form 1) 分子名称: 5'-R(*UP*UP*GP*CP*GP*UP*CP*UP*CP*GP*(5BU)P*CP*GP*AP*CP*GP*AP*AP*GP*UP*CP*GP*C)-3' 著者 Kondo, J, Koganei, M. 登録日 2014-03-10 公開日 2016-05-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of the bacterial A1408U-mutant ribosomal decoding site (C2 form 1) To Be Published
4WRE	Crystal Structure of Surfactant Protein-A DEDN Mutant (E171D/P175E/R197N/K203D) Complexed with Inositol 分子名称: 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, CALCIUM ION, CHLORIDE ION, ... 著者 Rynkiewicz, M.J, Wu, H, Cafarella, T.R, Nikolaidis, N.M, Head, J.F, Seaton, B.A, McCormack, F.X. 登録日 2014-10-23 公開日 2016-02-10 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.751 Å) 主引用文献 Differential ligand binding specificities of the pulmonary collectins are determined by the conformational freedom of a surface loop To be published
8PSX	Tilapia Lake Virus polymerase in vRNA elongation state (transcriptase conformation) 分子名称: 5' vRNA end - vRNA loop (40-mer), MAGNESIUM ION, Polymerase acidic protein (PA-like), ... 著者 Arragain, B, Cusack, S. 登録日 2023-07-13 公開日 2023-12-27 実験手法 ELECTRON MICROSCOPY (2.96 Å) 主引用文献 Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family. Nat Commun, 14, 2023
8FKJ	Yeast ATP Synthase in conformation-3, at pH 6 分子名称: ATP synthase protein 8, ATP synthase subunit 4, mitochondrial, ... 著者 Sharma, S, Patel, H, Luo, M, Mueller, D.M, Liao, M. 登録日 2022-12-21 公開日 2024-01-24 最終更新日 2025-05-14 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F 1 -F o coupling. Nat.Struct.Mol.Biol., 31, 2024
4WY0	PdxS (G. stearothermophilus) co-crystallized with R5P in the presence of ammonia. 分子名称: 1,2-ETHANEDIOL, CACODYLATE ION, PHOSPHATE ION, ... 著者 Smith, J.L, Smith, A.M. 登録日 2014-11-14 公開日 2015-01-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structures capture three states in the catalytic cycle of a pyridoxal phosphate (PLP) synthase. J.Biol.Chem., 290, 2015
4WZT	Crystal structure of P domain from norovirus strain NSW0514 in complex with HBGA type A (triglycan) 分子名称: 1,2-ETHANEDIOL, VP1, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]alpha-D-galactopyranose 著者 Singh, B.K, Hansman, G.S. 登録日 2014-11-20 公開日 2014-12-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Human noroviruses' fondness for histo-blood group antigens. J.Virol., 89, 2015
8PSZ	Tilapia Lake Virus polymerase in vRNA elongation state with additional mode B promoter (transcriptase conformation) 分子名称: 5' vRNA end - vRNA loop (40-mer), MAGNESIUM ION, Polymerase acidic protein (PA-like), ... 著者 Arragain, B, Cusack, S. 登録日 2023-07-13 公開日 2024-01-10 実験手法 ELECTRON MICROSCOPY (2.42 Å) 主引用文献 Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family. Nat Commun, 14, 2023

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