PDB: 1911 件ウェブページステータス検索Chemie searchBIRD

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6BQF	Pol II elongation complex with 'dT-AP' at i+1, i-1 position 分子名称: DNA (5'-D(P*CP*TP*(3DR)P*CP*TP*CP*TP*TP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... 著者 Wang, W, Wang, D. 登録日 2017-11-27 公開日 2018-02-28 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8UHD	Structure of paused transcription complex Pol II-DSIF-NELF - post-translocated 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ... 著者 Su, B.G, Vos, S.M. 登録日 2023-10-08 公開日 2024-03-20 最終更新日 2024-09-11 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing. Mol.Cell, 84, 2024
6BLP	Pol II elongation complex with an abasic lesion at i+1 position, soaking AMPCPP 分子名称: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA (5'-D(P*AP*(3DR)P*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... 著者 Wang, W, Wang, D. 登録日 2017-11-11 公開日 2018-02-28 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.203 Å) 主引用文献 Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BLO	Pol II elongation complex with an abasic lesion at i+1 position 分子名称: DNA (5'-D(P*AP*(3DR)P*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... 著者 Wang, W, Wang, D. 登録日 2017-11-10 公開日 2018-02-28 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.401 Å) 主引用文献 Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8UIS	Structure of transcription complex Pol II-DSIF-NELF-TFIIS 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ... 著者 Su, B.G, Vos, S.M. 登録日 2023-10-10 公開日 2024-03-20 最終更新日 2024-04-17 実験手法 ELECTRON MICROSCOPY (3.23 Å) 主引用文献 Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing. Mol.Cell, 84, 2024
8OEU	Structure of the mammalian Pol II-SPT6 complex (composite structure, Structure 4) 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... 著者 Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P. 登録日 2023-03-13 公開日 2023-10-18 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (3.04 Å) 主引用文献 Structure of the transcribing RNA polymerase II-Elongin complex. Nat.Struct.Mol.Biol., 30, 2023
3J1N	Cryo-EM map of a yeast minimal preinitiation complex interacting with the Mediator Head module 分子名称: DNA-directed RNA polymerase II subunit RPABC1, DNA-directed RNA polymerase II subunit RPABC2, DNA-directed RNA polymerase II subunit RPABC3, ... 著者 Asturias, F.J, Imasaki, T. 登録日 2012-03-29 公開日 2013-03-06 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (16 Å) 主引用文献 Interaction of the mediator head module with RNA polymerase II. Structure, 20, 2012
5W4U	Pol II elongation complex with an N6-methyladenine-containing template 分子名称: 14mer non-template DNA, 29mer template DNA, 9mer RNA, ... 著者 Wang, W, Wang, D. 登録日 2017-06-13 公開日 2018-06-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Epigenetic DNA Modification N6-Methyladenine Causes Site-Specific RNA Polymerase II Transcriptional Pausing. J.Am.Chem.Soc., 139, 2017
5W51	Pol II elongation complex with an N6-methyladenine-containing template and a matched UMPNPP 分子名称: 14mer non-template DNA, 29mer template DNA, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, ... 著者 Wang, W, Wang, D. 登録日 2017-06-13 公開日 2018-06-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.404 Å) 主引用文献 Epigenetic DNA Modification N6-Methyladenine Causes Site-Specific RNA Polymerase II Transcriptional Pausing. J.Am.Chem.Soc., 139, 2017
8OKI	Cryo-EM structure of Pyrococcus furiosus transcription elongation complex bound to Spt4/5 分子名称: DNA Non-Template Strand, DNA Template Strand, DNA-directed RNA polymerase subunit Rpo10, ... 著者 Tarau, D.M, Reichelt, R, Heiss, F.B, Pilsl, M, Hausner, W, Engel, C, Grohmann, D. 登録日 2023-03-28 公開日 2024-04-24 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.45 Å) 主引用文献 Structural basis of archaeal RNA polymerase transcription elongation and Spt4/5 recruitment. Nucleic Acids Res., 52, 2024
8WA1	The cryo-EM structure of the Nicotiana tabacum PEP-PAP-TEC2 分子名称: DNA (24-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Wu, X.X, Zhang, Y. 登録日 2023-09-06 公開日 2024-03-13 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Cryo-EM structures of the plant plastid-encoded RNA polymerase. Cell, 187, 2024
8W9Z	The cryo-EM structure of the Nicotiana tabacum PEP-PAP 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta'', ... 著者 Wu, X.X, Zhang, Y. 登録日 2023-09-06 公開日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Cryo-EM structures of the plant plastid-encoded RNA polymerase. Cell, 187, 2024
8WA0	The cryo-EM structure of the Nicotiana tabacum PEP-PAP-TEC1 分子名称: DNA (48-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Wu, X.X, Zhang, Y. 登録日 2023-09-06 公開日 2024-03-13 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Cryo-EM structures of the plant plastid-encoded RNA polymerase. Cell, 187, 2024
4Y3C	I304V 3D polymerase mutant of EMCV 分子名称: 3D polymerase, CHLORIDE ION, GLYCEROL 著者 Verdaguer, N, Ferrer-Orta, C, Vives-Adrian, L. 登録日 2015-02-10 公開日 2015-04-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family. Plos Pathog., 11, 2015
4Y34	Crystal Structure of Coxsackievirus B3 3D polymerase in complex with GPC-N143 分子名称: 2,2'-[(4-fluorobenzene-1,2-diyl)bis(oxy)]bis(5-nitrobenzonitrile), 3D polymerase, GLYCEROL, ... 著者 Vives-Adrian, L, Ferrer-Orta, C, Cerdaguer, N. 登録日 2015-02-10 公開日 2015-04-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family. Plos Pathog., 11, 2015
4Y2A	Crystal Structure of Coxsackie Virus B3 3D polymerase in complex with GPC-N114 inhibitor 分子名称: 2,2'-[(4-chlorobenzene-1,2-diyl)bis(oxy)]bis(5-nitrobenzonitrile), 3D polymerase, GLYCEROL, ... 著者 Vives-Adrian, L, Ferrer-Orta, C, Verdaguer, N. 登録日 2015-02-09 公開日 2015-04-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family. Plos Pathog., 11, 2015
1DZF	RPB5 from S.cerevisiae 分子名称: DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1 著者 Todone, F, Weinzierl, R.O.J, Brick, P, Onesti, S. 登録日 2000-02-25 公開日 2000-06-09 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of Rpb5, a Universal Eukaryotic RNA Polymerase Subunit and Transcription Factor Interaction Target Proc.Natl.Acad.Sci.USA, 97, 2000
7M8E	E.coli RNAP-RapA elongation complex 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Shi, W, Liu, B. 登録日 2021-03-29 公開日 2021-08-18 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural basis for activation of Swi2/Snf2 ATPase RapA by RNA polymerase. Nucleic Acids Res., 49, 2021
8FPI	Co-structure of the Respiratory Syncytial Virus RNA-dependent RNA polymerase with MRK-1 分子名称: 4-(2-aminopropan-2-yl)-N'-[4-(cyclopropyloxy)-3-methoxybenzoyl]-6-(4-fluorophenyl)pyridine-2-carbohydrazide, Phosphoprotein, RNA-directed RNA polymerase L 著者 Fischmann, T.O. 登録日 2023-01-04 公開日 2023-06-14 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.52 Å) 主引用文献 Conserved allosteric inhibitory site on the respiratory syncytial virus and human metapneumovirus RNA-dependent RNA polymerases. Commun Biol, 6, 2023
3NAI	Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase 分子名称: 5-FLUOROURACIL, GLYCEROL, MAGNESIUM ION, ... 著者 Kim, K.H, Lee, J.H, Alam, I, Park, Y, Kang, S. 登録日 2010-06-02 公開日 2011-06-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase To be Published
5IHE	D-family DNA polymerase - DP1 subunit (3'-5' proof-reading exonuclease) 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, ACETATE ION, ... 著者 Sauguet, L, Raia, P, De Larue, M. 登録日 2016-02-29 公開日 2016-08-31 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Shared active site architecture between archaeal PolD and multi-subunit RNA polymerases revealed by X-ray crystallography. Nat Commun, 7, 2016
4JXT	CID of human RPRD1A in complex with a phosphorylated peptide from RPB1-CTD 分子名称: DNA-directed RNA polymerase II subunit RPB1, Regulation of nuclear pre-mRNA domain-containing protein 1A, UNKNOWN ATOM OR ION 著者 Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Guo, X, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC) 登録日 2013-03-28 公開日 2013-11-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation. Nat.Struct.Mol.Biol., 21, 2014
1F78	SOLUTION STRUCTURE OF RNASE P RNA (M1 RNA) P4 STEM OLIGORIBONUCLEOTIDE COMPLEXED WITH COBALT (III) HEXAMINE, NMR, MINIMIZED AVERAGE STRUCTURE 分子名称: COBALT HEXAMMINE(III), RNASE P RNA RIBOZYME, P4 DOMAIN 著者 Schmitz, M, Tinoco Jr, I. 登録日 2000-06-26 公開日 2000-10-09 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure and metal-ion binding of the P4 element from bacterial RNase P RNA. RNA, 6, 2000
1F79	SOLUTION STRUCTURE OF RNASE P RNA (M1 RNA) P4 STEM C70U MUTANT OLIGORIBONUCLEOTIDE COMPLEXED WITH COBALT(III) HEXAMMINE, NMR, MINIMIZED AVERAGE STRUCTURE 分子名称: COBALT HEXAMMINE(III), RNASE P RNA RIBOZYME, P4 DOMAIN MUTANT 著者 Schmitz, M, Tinoco Jr, I. 登録日 2000-06-23 公開日 2000-10-09 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure and metal-ion binding of the P4 element from bacterial RNase P RNA. RNA, 6, 2000
1F7H	SOLUTION STRUCTURE OF THE RNASE P RNA (M1 RNA) P4 STEM OLIGORIBONUCLEOTIDE COMPLEXED WITH COBALT (III) HEXAMINE, NMR, ENSEMBLE OF 11 STRUCTURES 分子名称: COBALT HEXAMMINE(III), RNASE P RNA RIBOZYME, P4 DOMAIN 著者 Schmitz, M, Tinoco Jr, I. 登録日 2000-06-27 公開日 2000-10-09 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure and metal-ion binding of the P4 element from bacterial RNase P RNA. RNA, 6, 2000

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