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6TQE
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The structure of ABC transporter Rv1819c without addition of substrate
分子名称: ABC transporter ATP-binding protein/permease, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
著者Rempel, S, Gati, C, Slotboom, D.J, Guskov, A.
登録日2019-12-16
公開日2020-04-01
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds.
Nature, 580, 2020
6TMF
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Structure of an archaeal ABCE1-bound ribosomal post-splitting complex
分子名称: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Kratzat, H, Becker, T, Tampe, R, Beckmann, R.
登録日2019-12-04
公開日2020-02-12
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Molecular analysis of the ribosome recycling factor ABCE1 bound to the 30S post-splitting complex.
Embo J., 39, 2020
8EOP
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Cryo-EM Structure of Nanodisc reconstituted human ABCA7 EQ mutant in ATP bound closed state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Alam, A, Le, L.T.M, Thompson, J.R.
登録日2022-10-04
公開日2022-12-21
最終更新日2023-02-15
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms.
Embo J., 42, 2023
8F4B
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Bovine multidrug resistance protein 1 (MRP1) bound to cyclic peptide inhibitor 1 (CPI1)
分子名称: Cyclic peptide inhibitor 1 (CPI1), Multidrug resistance-associated protein 1
著者Pietz, H.L, Chen, J.
登録日2022-11-10
公開日2023-03-22
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献A macrocyclic peptide inhibitor traps MRP1 in a catalytically incompetent conformation.
Proc.Natl.Acad.Sci.USA, 120, 2023
5X3X
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2.8A resolution structure of a cobalt energy-coupling factor transporter-CbiMQO
分子名称: Cobalt ABC transporter ATP-binding protein, Cobalt transport protein CbiM, Uncharacterized protein CbiQ
著者Bao, Z, Qi, X, Wang, J, Zhang, P.
登録日2017-02-09
公開日2017-04-05
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.788 Å)
主引用文献Structure and mechanism of a group-I cobalt energy coupling factor transporter
Cell Res., 27, 2017
5XU1
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Structure of a non-canonical ABC transporter from Streptococcus pneumoniae R6
分子名称: ABC transporter ATP-binding protein, ABC transporter permeae, MAGNESIUM ION
著者Yang, H.B, Jiang, Y.L, Hou, W.T, Chen, M.T, Chen, Y, Zhou, C.Z.
登録日2017-06-22
公開日2018-01-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of a MacAB-like efflux pump from Streptococcus pneumoniae.
Nat Commun, 9, 2018
8F5B
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Human ABCA4 structure in complex with AMP-PNP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Scortecci, J.F, Van Petegem, F, Molday, R.S.
登録日2022-11-13
公開日2023-11-22
実験手法ELECTRON MICROSCOPY (3.95 Å)
主引用文献Structural and Functional Characterization of ABCA4 in its Nucleotide-Bound State
To Be Published
8FWK
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CryoEM structure of Human ABCB6 Transporter
分子名称: ATP-binding cassette sub-family B member 6
著者Shaik, M.M, Myasnikov, A.
登録日2023-01-22
公開日2023-02-08
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献CryoEM structure of Human ABCB6 Transporter
To Be Published
8FEF
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Structure of Mce1 transporter from Mycobacterium smegmatis (Map0)
分子名称: ABC transporter, ATP-binding protein,Green fluorescent protein chimera, ABC-transporter integral membrane protein, ...
著者Chen, J, Bhabha, G, Ekiert, D.C.
登録日2022-12-06
公開日2023-02-22
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (2.71 Å)
主引用文献Structure of an endogenous mycobacterial MCE lipid transporter.
Nature, 620, 2023
8FED
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Structure of Mce1-LucB complex from Mycobacterium smegmatis (Map1)
分子名称: ABC transporter, ATP-binding protein,Green fluorescent protein chimera, ABC-transporter integral membrane protein, ...
著者Chen, J, Bhabha, G, Ekiert, D.C.
登録日2022-12-06
公開日2023-02-22
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Structure of an endogenous mycobacterial MCE lipid transporter.
Nature, 620, 2023
8FEE
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Structure of Mce1 transporter from Mycobacterium smegmatis in the absence of LucB (Map2)
分子名称: ABC transporter, ATP-binding protein,Green fluorescent protein chimera, ABC-transporter integral membrane protein, ...
著者Chen, J, Bhabha, G, Ekiert, D.C.
登録日2022-12-06
公開日2023-02-22
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure of an endogenous mycobacterial MCE lipid transporter.
Nature, 620, 2023
8FZQ
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Dehosphorylated, ATP-bound human cystic fibrosis transmembrane conductance regulator (CFTR)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION
著者Levring, J, Terry, D.S, Kilic, Z, Fitzgerald, G.A, Blanchard, S.C, Chen, J.
登録日2023-01-29
公開日2023-03-29
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献CFTR function, pathology and pharmacology at single-molecule resolution.
Nature, 616, 2023
5YKF
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Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (3D class1 at 4.33A)
分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ...
著者Chen, L, Wu, J.X.
登録日2017-10-14
公開日2018-04-18
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (4.33 Å)
主引用文献Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
8G3F
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BceAB-S nucleotide free BceS state 1
分子名称: Bacitracin export ATP-binding protein BceA, Bacitracin export permease protein BceB, OLEIC ACID, ...
著者George, N.L, Orlando, B.J.
登録日2023-02-07
公開日2023-06-21
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Architecture of a complete Bce-type antimicrobial peptide resistance module.
Nat Commun, 14, 2023
8G3B
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BceAB-S nucleotide free TM state 2
分子名称: Bacitracin export ATP-binding protein BceA, Bacitracin export permease protein BceB, OLEIC ACID, ...
著者George, N.L, Orlando, B.J.
登録日2023-02-07
公開日2023-06-21
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Architecture of a complete Bce-type antimicrobial peptide resistance module.
Nat Commun, 14, 2023
8FMV
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Heterodimeric ABC transporter BmrCD in the inward-facing conformation bound to substrate and ATP: BmrCD_IF-2HT/ATP
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Tang, Q, Mchaourab, H.
登録日2022-12-24
公開日2023-11-15
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (3.34 Å)
主引用文献Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter.
Nat Commun, 14, 2023
8FHK
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Heterodimeric ABC transporter BmrCD in the occluded conformation bound to ATP: BmrCD_OC-ATP
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Tang, Q, Mchaourab, H.
登録日2022-12-14
公開日2023-11-15
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter.
Nat Commun, 14, 2023
5YKG
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Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (Class2 at 4.57A)
分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ...
著者Chen, L, Wu, J.X.
登録日2017-10-14
公開日2018-04-18
最終更新日2018-06-13
実験手法ELECTRON MICROSCOPY (4.57 Å)
主引用文献Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
8FPF
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Heterodimeric ABC transporter BmrCD in the inward-facing conformation bound to ATP: BmrCD_IF-ATP
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH, ...
著者Qingyu, T, Hassane, M.
登録日2023-01-04
公開日2023-11-22
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter
Nat Commun, 14, 2023
8FRP
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Acinetobacter baylyi LptB2FGC
分子名称: LPS export ABC transporter permease LptG, Lipopolysaccharide export system ATP-binding protein LptB, Lipopolysaccharide export system permease protein LptF, ...
著者Pahil, K.S, Gilman, M.S.A, Kruse, A.C, Kahne, D.
登録日2023-01-07
公開日2024-01-03
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献A new antibiotic traps lipopolysaccharide in its intermembrane transporter.
Nature, 625, 2024
8FRM
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Acinetobacter baylyi LptB2FG bound to lipopolysaccharide.
分子名称: (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-5-[(2~{S},3~{S},4~{R},5~{R},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{R},5~{S},6~{R})-6-[(1~{S})-2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-1-oxidanyl-ethyl]-3,4-bis(oxidanyl)-5-phosphonooxy-oxan-2-yl]oxy-3-oxidanyl-5-phosphonooxy-oxan-2-yl]oxy-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, LPS export ABC transporter permease LptG, Lipopolysaccharide export system ATP-binding protein LptB, ...
著者Pahil, K.S, Gilman, M.S.A, Kruse, A.C, Kahne, D.
登録日2023-01-07
公開日2024-01-03
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.14 Å)
主引用文献A new antibiotic traps lipopolysaccharide in its intermembrane transporter.
Nature, 625, 2024
8FRL
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Acinetobacter baylyi LptB2FG bound to lipopolysaccharide and a macrocyclic peptide
分子名称: (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-5-[(2~{S},3~{S},4~{R},5~{R},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{R},5~{S},6~{R})-6-[(1~{S})-2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-1-oxidanyl-ethyl]-3,4-bis(oxidanyl)-5-phosphonooxy-oxan-2-yl]oxy-3-oxidanyl-5-phosphonooxy-oxan-2-yl]oxy-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, (7S,10S,13S,17P)-10-(4-aminobutyl)-7-(3-aminopropyl)-17-(6-aminopyridin-3-yl)-20-chloro-13-[(1H-indol-3-yl)methyl]-12-methyl-6,7,9,10,12,13,15,16-octahydropyrido[2,3-b][1,5,8,11,14]benzothiatetraazacycloheptadecine-8,11,14(5H)-trione, DODECYL-BETA-D-MALTOSIDE, ...
著者Pahil, K.S, Gilman, M.S.A, Kruse, A.C, Kahne, D.
登録日2023-01-07
公開日2024-01-03
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献A new antibiotic traps lipopolysaccharide in its intermembrane transporter.
Nature, 625, 2024
8FRN
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Acinetobacter baylyi LptB2FG bound to lipopolysaccharide and Zosurabalpin
分子名称: (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-5-[(2~{S},3~{S},4~{R},5~{R},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{R},5~{S},6~{R})-6-[(1~{S})-2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-1-oxidanyl-ethyl]-3,4-bis(oxidanyl)-5-phosphonooxy-oxan-2-yl]oxy-3-oxidanyl-5-phosphonooxy-oxan-2-yl]oxy-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, DODECYL-BETA-D-MALTOSIDE, LPS export ABC transporter permease LptG, ...
著者Pahil, K.S, Gilman, M.S.A, Kruse, A.C, Kahne, D.
登録日2023-01-07
公開日2024-01-03
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献A new antibiotic traps lipopolysaccharide in its intermembrane transporter.
Nature, 625, 2024
8FRO
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Acinetobacter baylyi LptB2FG bound to lipopolysaccharide and a macrocyclic peptide
分子名称: (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-5-[(2~{S},3~{S},4~{R},5~{R},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{R},5~{S},6~{R})-6-[(1~{S})-2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-1-oxidanyl-ethyl]-3,4-bis(oxidanyl)-5-phosphonooxy-oxan-2-yl]oxy-3-oxidanyl-5-phosphonooxy-oxan-2-yl]oxy-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, (7S,10S,13S)-10-(4-aminobutyl)-7-(3-aminopropyl)-17,20-dichloro-13-[(1H-indol-3-yl)methyl]-12-methyl-6,7,9,10,12,13,15,16-octahydropyrido[2,3-b][1,5,8,11,14]benzothiatetraazacycloheptadecine-8,11,14(5H)-trione, LPS export ABC transporter permease LptG, ...
著者Pahil, K.S, Gilman, M.S.A, Kruse, A.C, Kahne, D.
登録日2023-01-07
公開日2024-01-03
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献A new antibiotic traps lipopolysaccharide in its intermembrane transporter.
Nature, 625, 2024
5YKE
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Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (focused refinement on TM at 4.11A)
分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11
著者Chen, L, Wu, J.X.
登録日2017-10-14
公開日2018-04-18
最終更新日2018-06-13
実験手法ELECTRON MICROSCOPY (4.11 Å)
主引用文献Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018

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