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2LJM
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Solution Structure of CssII
分子名称: Beta-mammal toxin Css2
著者del Rio-Portilla, F, Saucedo, A.L, Corzo, G, Delepierre, M, Possani, L.D.
登録日2011-09-20
公開日2012-02-15
実験手法SOLUTION NMR
主引用文献Solution structure of native and recombinant expressed toxin CssII from the venom of the scorpion Centruroides suffusus suffusus, and their effects on Nav1.5 Sodium channels.
Biochim.Biophys.Acta, 1824, 2012
2MKN
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Structural Characterization of Interactions between the Double-Stranded RNA-Binding Zinc Finger Protein JAZ and dsRNA
分子名称: RNA (5'-R(*GP*CP*CP*GP*UP*GP*GP*UP*CP*UP*GP*GP*UP*GP*GP*CP*CP*GP*G)-3'), RNA (5'-R(P*CP*CP*GP*GP*CP*CP*AP*CP*CP*AP*GP*AP*CP*CP*AP*CP*GP*GP*C)-3'), ZINC ION, ...
著者Wright, P, Dyson, J, Burge, R, Martinez-Yamout, M.
登録日2014-02-10
公開日2014-03-19
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural Characterization of Interactions between the Double-Stranded RNA-Binding Zinc Finger Protein JAZ and Nucleic Acids.
Biochemistry, 53, 2014
2L6T
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Efficacy of an HIV-1 entry inhibitor targeting the GP41 fusion peptide
分子名称: VIR-576
著者Forssmann, W, The, Y, Stoll, M, Adermann, K, Albrecht, U, Barlos, K, Busmann, A, Can les-Mayordomo, A, Gimenez-Gallego, G, Hirsch, J, Jimenez-Barbero, J, Meyer-Olson, D, Muench, J, Perez-Castells, J, Staendker, L, Kirchhoff, F, Schmidt, R.E.
登録日2010-11-24
公開日2011-01-19
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Short-term monotherapy in HIV-infected patients with a virus entry inhibitor against the gp41 fusion peptide.
Sci Transl Med, 2, 2010
2LI7
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Solution Structure of CssII
分子名称: Beta-mammal toxin Css2
著者del Rio-Portilla, F, Saucedo, A.L, Corzo, G, Delepierre, M, Possani, L.D.
登録日2011-08-24
公開日2012-02-15
実験手法SOLUTION NMR
主引用文献Solution structure of native and recombinant expressed toxin CssII from the venom of the scorpion Centruroides suffusus suffusus, and their effects on Nav1.5 Sodium channels.
Biochim.Biophys.Acta, 1824, 2012
2MNB
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Thiazotropsin B DNA recognition sequence d(CGACGCGTCG)2
分子名称: 5'-D(*CP*GP*AP*CP*GP*CP*GP*TP*CP*G)-3'
著者Alniss, H.Y, Salvia, M.-V, Sadikov, M, Golovchenko, I, Anthony, N.G, Khalaf, A.I, Mackay, S.P, Suckling, C.J, Parkinson, J.A.
登録日2014-04-02
公開日2014-09-17
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Recognition of the DNA minor groove by thiazotropsin analogues.
Chembiochem, 15, 2014
2R3N
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Crystal Structure of Cyclin-Dependent Kinase 2 with inhibitor
分子名称: 3-cyclopropyl-5-phenyl-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine, Cell division protein kinase 2
著者Fischmann, T.O, Hruza, A.W, Madison, V.M, Duca, J.S.
登録日2007-08-29
公開日2008-01-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Structure-guided discovery of cyclin-dependent kinase inhibitors.
Biopolymers, 89, 2008
2QU8
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Crystal structure of putative nucleolar GTP-binding protein 1 PFF0625w from Plasmodium falciparum
分子名称: GUANOSINE-5'-DIPHOSPHATE, Putative nucleolar GTP-binding protein 1
著者Wernimont, A.K, Lew, J, Lin, Y.H, Kozieradzki, I, Zhao, Y, Ravichandran, M, Shapiro, M, Bochkarev, A, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Hui, R, Qiu, W, Sukumar, D, Hassanali, A, Structural Genomics Consortium (SGC)
登録日2007-08-03
公開日2007-08-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Crystal structure of putative nucleolar GTP-binding protein 1 PFF0625w from Plasmodium falciparum.
To be Published
2QOM
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The crystal structure of the E.coli EspP autotransporter Beta-domain.
分子名称: Serine protease espP
著者Barnard, T.J, Dautin, N, Lukacik, P, Bernstein, H.D, Buchanan, S.K.
登録日2007-07-20
公開日2007-11-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Autotransporter structure reveals intra-barrel cleavage followed by conformational changes.
Nat.Struct.Mol.Biol., 14, 2007
2R3G
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Crystal Structure of Cyclin-Dependent Kinase 2 with inhibitor
分子名称: 6-(2-fluorophenyl)-N-(pyridin-3-ylmethyl)imidazo[1,2-a]pyrazin-8-amine, Cell division protein kinase 2
著者Fischmann, T.O, Hruza, A.W, Madison, V.M, Duca, J.S.
登録日2007-08-29
公開日2008-01-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure-guided discovery of cyclin-dependent kinase inhibitors.
Biopolymers, 89, 2008
2R44
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CRYSTAL STRUCTURE OF A PUTATIVE ATPASE (CHU_0153) FROM CYTOPHAGA HUTCHINSONII ATCC 33406 AT 2.00 A RESOLUTION
分子名称: PHOSPHATE ION, TETRAETHYLENE GLYCOL, Uncharacterized protein
著者Joint Center for Structural Genomics (JCSG)
登録日2007-08-30
公開日2007-09-18
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of putative ATPase (YP_676785.1) from Cytophaga hutchinsonii ATCC 33406 at 2.00 A resolution
To be published
2QIQ
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Structure-based Design and Synthesis and Biological Evaluation of Peptidomimetic SARS-3CLpro Inhibitors
分子名称: ETHYL (4R)-4-{[(2R,5S)-5-{[N-(TERT-BUTOXYCARBONYL)-L-SERYL]AMINO}-6-METHYL-2-(3-METHYLBUT-2-EN-1-YL)-4-OXOHEPTANOYL]AMINO}-5-[(3R)-2-OXOPYRROLIDIN-3-YL]PENTANOATE, Replicase polyprotein 1ab
著者Grum-Tokars, V.
登録日2007-07-05
公開日2008-02-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure-based design, synthesis, and biological evaluation of peptidomimetic SARS-CoV 3CLpro inhibitors.
Bioorg.Med.Chem.Lett., 17, 2007
2QJ9
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Crystal structure analysis of BMP-2 in complex with BMPR-IA variant B1
分子名称: Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA
著者Kotzsch, A, Mueller, T.D.
登録日2007-07-06
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome.
J.Biol.Chem., 283, 2008
2QFS
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E.coli EPSP synthase Pro101Ser liganded with S3P
分子名称: 3-phosphoshikimate 1-carboxyvinyltransferase, FORMIC ACID, SHIKIMATE-3-PHOSPHATE
著者Schonbrunn, E, Healy-Fried, M.L.
登録日2007-06-28
公開日2007-10-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural basis of glyphosate tolerance resulting from mutations of Pro101 in Escherichia coli 5-enolpyruvylshikimate-3-phosphate synthase.
J.Biol.Chem., 282, 2007
2QTJ
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BU of 2qtj by Molmil
Solution structure of human dimeric immunoglobulin A
分子名称: Ig alpha-1 chain C region, Kappa light chain IgA1
著者Bonner, A, Furtado, P.B, Almogren, A, Kerr, M.A, Perkins, S.J.
登録日2007-08-02
公開日2008-01-22
最終更新日2024-02-21
実験手法SOLUTION SCATTERING
主引用文献Implications of the near-planar solution structure of human myeloma dimeric IgA1 for mucosal immunity and IgA nephropathy
J.Immunol., 180, 2008
2QJA
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Crystal structure analysis of BMP-2 in complex with BMPR-IA variant B12
分子名称: Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA
著者Kotzsch, A, Mueller, T.D.
登録日2007-07-06
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome.
J.Biol.Chem., 283, 2008
2QK7
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A covalent S-F heterodimer of staphylococcal gamma-hemolysin
分子名称: Gamma-hemolysin component A, Gamma-hemolysin component B
著者Roblin, P, Guillet, V, Maveyraud, L, Mourey, L.
登録日2007-07-10
公開日2008-02-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A covalent S-F heterodimer of leucotoxin reveals molecular plasticity of beta-barrel pore-forming toxins.
Proteins, 71, 2008
2QDJ
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Crystal structure of the Retinoblastoma protein N-domain provides insight into tumor suppression, ligand interaction and holoprotein architecture
分子名称: Retinoblastoma-associated protein
著者Hassler, M, Mittnacht, S, Pearl, L.H.
登録日2007-06-21
公開日2008-01-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the retinoblastoma protein N domain provides insight into tumor suppression, ligand interaction, and holoprotein architecture.
Mol.Cell, 28, 2007
2QEP
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Crystal structure of the D1 domain of PTPRN2 (IA2beta)
分子名称: CHLORIDE ION, Receptor-type tyrosine-protein phosphatase N2
著者Ugochukwu, E, Barr, A, Alfano, I, Berridge, G, Burgess-Brown, N, Das, S, Fedorov, O, King, O, Niesen, F, Watt, S, Savitsky, P, Salah, E, Pike, A.C.W, Bunkoczi, G, von Delft, F, Sundstrom, M, Edwards, A, Arrowsmith, C.H, Weigelt, J, Knapp, S, Structural Genomics Consortium (SGC)
登録日2007-06-26
公開日2007-07-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Large-scale structural analysis of the classical human protein tyrosine phosphatome.
Cell(Cambridge,Mass.), 136, 2009
2QJB
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Crystal structure analysis of BMP-2 in complex with BMPR-IA variant IA/IB
分子名称: Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA, CHLORIDE ION
著者Kotzsch, A, Mueller, T.D.
登録日2007-07-06
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome.
J.Biol.Chem., 283, 2008
2QNI
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Crystal structure of uncharacterized protein Atu0299
分子名称: Uncharacterized protein Atu0299
著者Dong, A, Xu, X, Gu, J, Zheng, H, Edwards, A.M, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG)
登録日2007-07-18
公開日2007-08-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of uncharacterized protein Atu0299.
To be Published
2QO0
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Crystal structure of the complex between the A246F mutant of mycobacterium beta-ketoacyl-acyl carrier protein synthase III (FABH) and 11-(decyldithiocarbonyloxy)-undecanoic acid
分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 3, DECANE-1-THIOL
著者Sachdeva, S, Musayev, F, Alhamadsheh, M, Scarsdale, J.N, Wright, H.T, Reynolds, K.A.
登録日2007-07-19
公開日2008-05-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Separate Entrance and Exit Portals for Ligand Traffic in Mycobacterium tuberculosis FabH
Chem.Biol., 15, 2008
2QSS
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Bovine hemoglobin at pH 6.3
分子名称: CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ...
著者Aranda IV, R, Richards, M.P, Phillips Jr, G.N.
登録日2007-07-31
公開日2008-09-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural analysis of fish versus mammalian hemoglobins: Effect of the heme pocket environment on autooxidation and hemin loss.
Proteins, 75, 2008
2QPQ
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Structure of Bug27 from Bordetella pertussis
分子名称: CITRIC ACID, protein Bug27
著者Herrou, J, Bompard, C.
登録日2007-07-25
公開日2007-08-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Structure-based mechanism of ligand binding for periplasmic solute-binding protein of the Bug family.
J.Mol.Biol., 373, 2007
2QZV
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Draft Crystal Structure of the Vault Shell at 9 Angstroms Resolution
分子名称: Major vault protein
著者Anderson, D.H, Kickhoefer, V.A, Sievers, S.A, Rome, L.H, Eisenberg, D.
登録日2007-08-17
公開日2007-12-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (9 Å)
主引用文献Draft crystal structure of the vault shell at 9-A resolution.
Plos Biol., 5, 2007
2QZS
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Crystal Structure of Wild-type E.coli GS in complex with ADP and Glucose(wtGSb)
分子名称: (2R)-2-hydroxy-3-[4-(2-hydroxyethyl)piperazin-1-yl]propane-1-sulfonic acid, ADENOSINE-5'-DIPHOSPHATE, alpha-D-glucopyranose, ...
著者Sheng, F, Geiger, J.
登録日2007-08-17
公開日2008-09-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Crystal Structures of the Open and Catalytically Competent Closed Conformation of Escherichia coli Glycogen Synthase.
J.Biol.Chem., 284, 2009

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