PDB: 217477 件ウェブページステータス検索Chemie searchBIRD

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1SOJ	CATALYTIC DOMAIN OF HUMAN PHOSPHODIESTERASE 3B IN COMPLEX WITH IBMX 分子名称: 3-ISOBUTYL-1-METHYLXANTHINE, MAGNESIUM ION, cGMP-inhibited 3',5'-cyclic phosphodiesterase B 著者 Scapin, G, Patel, S.B, Chung, C, Varnerin, J.P, Edmondson, S.D, Mastracchio, A, Parmee, E.R, Becker, J.W, Singh, S.B, Van Der Ploeg, L.H, Tota, M.R. 登録日 2004-03-15 公開日 2004-05-11 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal Structure of Human Phosphodiesterase 3B: Atomic Basis for Substrate and Inhibitor Specificity Biochemistry, 43, 2004
6KUR	Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B1) 分子名称: 3'-vRNA, 5'-vRNA, Polymerase 3, ... 著者 Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. 登録日 2019-09-02 公開日 2019-10-02 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural insight into RNA synthesis by influenza D polymerase. Nat Microbiol, 4, 2019
3MUJ	Early B-cell factor 3 (EBF3) IPT/TIG and dimerization helices 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Transcription factor COE3 著者 Siponen, M.I, Lehtio, L, Arrowsmith, C.H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Schueler, H, Schutz, P, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Wisniewska, M, Berglund, H, Structural Genomics Consortium (SGC) 登録日 2010-05-03 公開日 2010-06-30 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Structural Determination of Functional Domains in Early B-cell Factor (EBF) Family of Transcription Factors Reveals Similarities to Rel DNA-binding Proteins and a Novel Dimerization Motif. J.Biol.Chem., 285, 2010
1SHX	Ephrin A5 ligand structure 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin-A5 著者 Himanen, J.P, Barton, W.A, Nikolov, D.B, Jeffrey, P.D. 登録日 2004-02-26 公開日 2005-04-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Three distinct molecular surfaces in ephrin-A5 are essential for a functional interaction with EphA3. J.Biol.Chem., 280, 2005
2Z66	Crystal structure of the VT3 hybrid of human TLR4 and hagfish VLRB.61 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Variable lymphocyte receptor B, ... 著者 Lee, J.-O, Kim, H.M, Park, B.S. 登録日 2007-07-22 公開日 2007-09-18 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran Cell(Cambridge,Mass.), 130, 2007
4KU8	Structures of PKGI Reveal a cGMP-Selective Activation Mechanism 分子名称: GLYCINE, cGMP-dependent Protein Kinase 1 著者 Huang, G.Y, Kim, J.J, Reger, A.S, Lorenz, R, Moon, E.W, Casteel, D.E, Sankaran, B, Herberg, F.W, Kim, C. 登録日 2013-05-21 公開日 2014-01-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.994 Å) 主引用文献 Structural Basis for Cyclic-Nucleotide Selectivity and cGMP-Selective Activation of PKG I. Structure, 22, 2014
1F0W	CRYSTAL STRUCTURE OF ORTHORHOMBIC LYSOZYME GROWN AT PH 6.5 分子名称: LYSOZYME 著者 Biswal, B.K, Sukumar, N, Vijayan, M. 登録日 2000-05-17 公開日 2000-06-21 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Hydration, mobility and accessibility of lysozyme: structures of a pH 6.5 orthorhombic form and its low-humidity variant and a comparative study involving 20 crystallographically independent molecules. Acta Crystallogr.,Sect.D, 56, 2000
8C0O	African cichlid nackednavirus capsid at pH 5.5 分子名称: C protein 著者 Pfister, S, Rabl, J, Boehringer, D, Meier, B.H. 登録日 2022-12-19 公開日 2023-04-05 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural conservation of HBV-like capsid proteins over hundreds of millions of years despite the shift from non-enveloped to enveloped life-style. Nat Commun, 14, 2023
8HRX	Cryo-EM structure of human NTCP-myr-preS1-YN9048Fab complex 分子名称: Fab heavy chain from antibody IgG clone number YN9048, Fab light chain from antibody IgG clone number YN9048, PreS1 protein (Fragment), ... 著者 Asami, J, Shimizu, T, Ohto, U. 登録日 2022-12-16 公開日 2024-01-17 最終更新日 2024-04-03 実験手法 ELECTRON MICROSCOPY (2.89 Å) 主引用文献 Structural basis of hepatitis B virus receptor binding. Nat.Struct.Mol.Biol., 31, 2024
1F10	CRYSTAL STRUCTURE OF ORTHORHOMBIC LYSOZYME GROWN AT PH 6.5 AT 88% RELATIVE HUMIDITY 分子名称: LYSOZYME 著者 Biswal, B.K, Sukumar, N, Vijayan, M. 登録日 2000-05-18 公開日 2000-06-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Hydration, mobility and accessibility of lysozyme: structures of a pH 6.5 orthorhombic form and its low-humidity variant and a comparative study involving 20 crystallographically independent molecules. Acta Crystallogr.,Sect.D, 56, 2000
5BTG	Crystal structure of a topoisomerase II complex 分子名称: (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid, DNA gyrase subunit A, DNA gyrase subunit B, ... 著者 Blower, T.R, Williamson, B.H, Kerns, R.J, Berger, J.M. 登録日 2015-06-03 公開日 2016-03-02 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure and stability of gyrase-fluoroquinolone cleaved complexes from Mycobacterium tuberculosis. Proc.Natl.Acad.Sci.USA, 113, 2016
6I96	Structure of the ferrioxamine B transporter FoxA from Pseudomonas aeruginosa in complex with ferrioxamine B 分子名称: Ferric hydroxamate uptake, Ferrioxamine B, GLYCEROL, ... 著者 Josts, I, Tidow, H. 登録日 2018-11-22 公開日 2019-08-28 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Ternary structure of the outer membrane transporter FoxA with resolved signalling domain provides insights into TonB-mediated siderophore uptake. Elife, 8, 2019
7KDP	HCMV prefusion gB in complex with fusion inhibitor WAY-174865 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Envelope glycoprotein B, ... 著者 Liu, Y, Heim, P.K, Che, Y, Chi, X, Qiu, X, Han, S, Dormitzer, P.R, Yang, X. 登録日 2020-10-09 公開日 2021-03-17 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Prefusion structure of human cytomegalovirus glycoprotein B and structural basis for membrane fusion. Sci Adv, 7, 2021
7K7G	nucleosome and Gal4 complex 分子名称: Centromere DNA-binding protein complex CBF3 subunit B, DNA (147-MER), Histone H2A.1, ... 著者 Ruifang, G, Yawen, B. 登録日 2020-09-22 公開日 2021-03-31 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation. Nat Commun, 12, 2021
1FGA	REFINEMENT OF THE STRUCTURE OF HUMAN BASIC FIBROBLAST GROWTH FACTOR AT 1.6 ANGSTROMS RESOLUTION AND ANALYSIS OF PRESUMED HEPARIN BINDING SITES BY SELENATE SUBSTITUTION 分子名称: BASIC FIBROBLAST GROWTH FACTOR, BETA-MERCAPTOETHANOL, SELENATE ION 著者 Eriksson, A.E, Matthews, B.W. 登録日 1993-02-26 公開日 1993-07-15 最終更新日 2020-07-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Refinement of the structure of human basic fibroblast growth factor at 1.6 A resolution and analysis of presumed heparin binding sites by selenate substitution. Protein Sci., 2, 1993
4M3L	Crystal Structure of the coiled coil domain of MuRF1 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, E3 ubiquitin-protein ligase TRIM63, ... 著者 Mayans, O, Franke, B. 登録日 2013-08-06 公開日 2014-03-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Molecular basis for the fold organization and sarcomeric targeting of the muscle atrogin MuRF1. Open Biol, 4, 2014
5IPI	Structure of Adeno-associated virus type 2 VLP 分子名称: Capsid protein VP1 著者 Drouin, L.M, Lins, B, Janssen, M.E, Bennet, A, Chipman, P, McKenna, R, Chen, W, Muzyczka, N, Cardone, G, Baker, T.S, Agbandje-McKenna, M. 登録日 2016-03-09 公開日 2016-07-20 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Cryo-electron Microscopy Reconstruction and Stability Studies of the Wild Type and the R432A Variant of Adeno-associated Virus Type 2 Reveal that Capsid Structural Stability Is a Major Factor in Genome Packaging. J.Virol., 90, 2016
6KUT	Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B2) 分子名称: 3'-vRNA, 5'-vRNA, Polymerase 3, ... 著者 Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. 登録日 2019-09-02 公開日 2019-10-02 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structural insight into RNA synthesis by influenza D polymerase. Nat Microbiol, 4, 2019
330D	BASE-PAIRING SHIFT IN THE MAJOR GROOVE OF (CA)N TRACTS BY B-DNA CRYSTAL STRUCTURES 分子名称: DNA (5'-D(*AP*CP*CP*GP*CP*CP*GP*GP*CP*GP*CP*C)-3'), DNA (5'-D(*GP*GP*CP*GP*CP*CP*GP*GP*CP*GP*GP*T)-3') 著者 Timsit, Y, Vilbois, E, Moras, D. 登録日 1997-04-29 公開日 1997-04-30 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Base-pairing shift in the major groove of (CA)n tracts by B-DNA crystal structures. Nature, 354, 1991
7YWZ	Modified oligopeptidase B from S. proteomaculans in intermediate conformation with 4 spermine molecules at 1.75 A resolution 分子名称: GLYCEROL, Oligopeptidase B, SPERMINE 著者 Petrenko, D.E, Boyko, K.M, Nikolaeva, A.Y, Vlaskina, A.V, Mikhailova, A.G, Timofeev, V.I, Rakitina, T.V. 登録日 2022-02-15 公開日 2023-02-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Modified oligopeptidase B from S. proteomaculans in intermediate conformation with 4 spermine molecules at 1.75 A resolution To Be Published
5TQX	CryoEM reconstruction of human IKK1, intermediate conformation 2 分子名称: Inhibitor of nuclear factor kappa-B kinase subunit alpha 著者 Lyumkis, D, Ghosh, G, Polley, S, Biswath, T, Huang, D, Passos, D.O. 登録日 2016-10-24 公開日 2016-11-09 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (5.4 Å) 主引用文献 Structural Basis for the Activation of IKK1/ alpha. Cell Rep, 17, 2016
4D71	Crystal structure of a family 98 glycoside hydrolase catalytic module (Sp3GH98) in complex with the type 2 blood group A-tetrasaccharide (E558A X02 mutant) 分子名称: 1,2-ETHANEDIOL, GLYCOSIDE HYDROLASE, SULFATE ION, ... 著者 Kwan, D.H, Constantinescu, I, Chapanian, R, Higgins, M.A, Samain, E, Boraston, A.B, Kizhakkedathu, J.N, Withers, S.G. 登録日 2014-11-19 公開日 2015-01-21 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Towards Efficient Enzymes for the Generation of Universal Blood Through Structure-Guided Directed Evolution. J.Am.Chem.Soc., 137, 2015
6A6H	Crystal Structure of Swine Major Histocompatibility Complex Class I SLA-2*040202 For 2.3 Angstrom 分子名称: Beta-2-microglobulin, MET-THR-ALA-HIS-ILE-VAL-VAL-PRO-TYR, MHC class I antigen 著者 Ning, S, Wang, Z.B. 登録日 2018-06-28 公開日 2019-07-03 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Crystallization of SLA-2*04:02:02 complexed with a CTL epitope derived from FMDV. Res. Vet. Sci., 128, 2019
7KE0	HIV-1 Integrase catalytic core domain complexed with allosteric inhibitor STP03-0404 分子名称: (2S)-tert-butoxy{4-(4-chlorophenyl)-2,3,6-trimethyl-1-[(1-methyl-1H-pyrazol-4-yl)methyl]-1H-pyrrolo[2,3-b]pyridin-5-yl}acetic acid, Integrase 著者 Lindenberger, J.J, Kvaratskhelia, M. 登録日 2020-10-09 公開日 2021-09-22 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 A highly potent and safe pyrrolopyridine-based allosteric HIV-1 integrase inhibitor targeting host LEDGF/p75-integrase interaction site. Plos Pathog., 17, 2021
5IS5	Discovery and Pharmacological Characterization of Novel Quinazoline-based PI3K delta-selective Inhibitors 分子名称: 5-{4-[3-(4-acetylpiperazine-1-carbonyl)phenyl]quinazolin-6-yl}-2-methoxypyridine-3-carbonitrile, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 著者 Gutmann, S, Rummel, G, Shrestha, B. 登録日 2016-03-15 公開日 2016-08-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Discovery and Pharmacological Characterization of Novel Quinazoline-Based PI3K Delta-Selective Inhibitors. Acs Med.Chem.Lett., 7, 2016

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