PDB: 30476 件ウェブページステータス検索Chemie searchBIRD

---

5HXZ	Structure-function analysis of functionally diverse members of the cyclic amide hydrolase family of Toblerone fold enzymes 分子名称: (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, Barbiturase, CHLORIDE ION, ... 著者 Peat, T.S, Balotra, S, Wilding, M, Newman, J, Scott, C. 登録日 2016-01-31 公開日 2017-02-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 High-Resolution X-Ray Structures of Two Functionally Distinct Members of the Cyclic Amide Hydrolase Family of Toblerone Fold Enzymes. Appl. Environ. Microbiol., 83, 2017
7N5Z	SARS-CoV-2 Main protease C145S mutant 分子名称: 3C-like proteinase 著者 Noske, G.D, Nakamura, A.M, Gawriljuk, V.O, Lima, G.M.A, Zeri, A.C.M, Nascimento, A.F.Z, Oliva, G, Godoy, A.S. 登録日 2021-06-07 公開日 2021-06-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 A Crystallographic Snapshot of SARS-CoV-2 Main Protease Maturation Process. J.Mol.Biol., 433, 2021
5HPR	Insulin with proline analog HyP at position B28 in the T2 state 分子名称: GLYCEROL, Insulin A-Chain, Insulin B-Chain, ... 著者 Lieblich, S.A, Fang, K.Y, Cahn, J.K.B, Tirrell, D.A. 登録日 2016-01-21 公開日 2017-01-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 4S-Hydroxylation of Insulin at ProB28 Accelerates Hexamer Dissociation and Delays Fibrillation. J. Am. Chem. Soc., 139, 2017
7NJ9	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-133 分子名称: 14-3-3 protein sigma, 4-(3,4-dihydro-2~{H}-quinolin-1-ylsulfonyl)benzaldehyde, DI(HYDROXYETHYL)ETHER, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-02-16 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7NJ6	14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1005 分子名称: 14-3-3 protein sigma, 4-[4-(trifluoromethyl)imidazol-1-yl]benzaldehyde, CALCIUM ION, ... 著者 Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. 登録日 2021-02-16 公開日 2021-06-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
7NJB	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-132 分子名称: 14-3-3 protein sigma, 4-piperidin-1-ylsulfonylbenzaldehyde, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-02-16 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7N6N	SARS-CoV-2 Main protease C145S mutant in complex with N and C-terminal residues 分子名称: 3C-like proteinase 著者 Noske, G.D, Nakamura, A.M, Gawriljuk, V.O, Lima, G.M.A, Zeri, A.C.M, Nascimento, A.F.Z, Fernandes, R.S, Oliva, G, Godoy, A.S. 登録日 2021-06-08 公開日 2021-06-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A Crystallographic Snapshot of SARS-CoV-2 Main Protease Maturation Process. J.Mol.Biol., 433, 2021
7N50	Structure of a bacterial gasdermin from Bradyrhizobium tropiciagri 分子名称: Gasdermin 著者 Johnson, A.G, Kranzusch, P.J. 登録日 2021-06-04 公開日 2021-06-23 最終更新日 2022-01-26 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Bacterial gasdermins reveal an ancient mechanism of cell death. Science, 375, 2022
7NJ8	14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1007 分子名称: 14-3-3 protein sigma, CALCIUM ION, MAGNESIUM ION, ... 著者 Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. 登録日 2021-02-16 公開日 2021-06-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
5HTS	Crystal structure of shaft pilin spaA from Lactobacillus rhamnosus GG - D295N mutant 分子名称: Cell surface protein SpaA 著者 Chaurasia, P, Pratap, S, von Ossowski, I, Palva, A, Krishnan, V. 登録日 2016-01-27 公開日 2016-07-20 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 New insights about pilus formation in gut-adapted Lactobacillus rhamnosus GG from the crystal structure of the SpaA backbone-pilin subunit Sci Rep, 6, 2016
5HVI	Crystal structure of TEM1 beta-lactamase 分子名称: Beta-lactamase TEM 著者 Roose, B.W, Dmochowski, I.J. 登録日 2016-01-28 公開日 2017-06-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 A Structural Basis for129Xe Hyper-CEST Signal in TEM-1 beta-Lactamase. Chemphyschem, 2018
7NQP	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound LvD1009 分子名称: 14-3-3 protein sigma, 2-bromanyl-4-(2-phenylimidazol-1-yl)benzaldehyde, MAGNESIUM ION, ... 著者 Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. 登録日 2021-03-02 公開日 2021-06-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.24 Å) 主引用文献 Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
7NIX	14-3-3 sigma with AS160 binding site pT642 分子名称: 14-3-3 protein sigma, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, MAGNESIUM ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-02-14 公開日 2021-06-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
7N52	Structure of a bacterial gasdermin from Runella zeae 分子名称: Gasdermin 著者 Johnson, A.G, Kranzusch, P.J. 登録日 2021-06-04 公開日 2021-06-23 最終更新日 2022-01-26 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Bacterial gasdermins reveal an ancient mechanism of cell death. Science, 375, 2022
5HOC	p73 homo-tetramerization domain mutant II 分子名称: Tumor protein p73 著者 Coutandin, D, Krojer, T, Salah, E, Mathea, S, Sumyk, M, Knapp, S, Dotsch, V. 登録日 2016-01-19 公開日 2016-10-19 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.36007786 Å) 主引用文献 Mechanism of TAp73 inhibition by Delta Np63 and structural basis of p63/p73 hetero-tetramerization. Cell Death Differ., 23, 2016
5HOG	Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Dna2. 分子名称: DNA polymerase alpha-binding protein, Dna2p 著者 Simon, A.C, Pellegrini, L. 登録日 2016-01-19 公開日 2016-06-22 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.092 Å) 主引用文献 Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase. Mol.Cell, 63, 2016
7NIG	14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1008 分子名称: 14-3-3 protein sigma, 2-bromanyl-4-imidazol-1-yl-benzaldehyde, CALCIUM ION, ... 著者 Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. 登録日 2021-02-12 公開日 2021-06-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
5HPE	Phosphatase domain of PP5 bound to a phosphomimetic Cdc37 substrate peptide 分子名称: COBALT HEXAMMINE(III), MANGANESE (II) ION, Serine/threonine-protein phosphatase 5,Hsp90 co-chaperone Cdc37 著者 Oberoi, J, Mariotti, L, Vaughan, C. 登録日 2016-01-20 公開日 2016-07-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Structural and functional basis of protein phosphatase 5 substrate specificity. Proc.Natl.Acad.Sci.USA, 113, 2016
7NEI	Polyester Hydrolase Leipzig 7 (PHL7) in the unliganded state 分子名称: Polyester Hydrolase Leipzig 7 (PHL-7), SODIUM ION 著者 Richter, P.K, Strater, N. 登録日 2021-02-04 公開日 2021-06-23 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Low Carbon Footprint Recycling of Post-Consumer PET Plastic with a Metagenomic Polyester Hydrolase. ChemSusChem, 15, 2022
5HYM	3-Hydroxybenzoate 6-hydroxylase from Rhodococcus jostii in complex with phosphatidylinositol 分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Phosphatidylinositol, ... 著者 Orru, R, Montersino, S, Mattevi, A, van Berkel, W.J.H. 登録日 2016-02-01 公開日 2017-02-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 3-Hydroxybenzoate 6-Hydroxylase from Rhodococcus jostii RHA1 Contains a Phosphatidylinositol Cofactor. Front Microbiol, 8, 2017
7N89	Room-temperature X-ray structure of SARS-CoV-2 main protease C145A mutant in complex with substrate Ac-SAVLQSGF-CONH2 分子名称: 3C-like proteinase, ACE-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-NH2 著者 Kovalevsky, A, Kneller, D.W, Coates, L. 登録日 2021-06-14 公開日 2021-06-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Michaelis-like complex of SARS-CoV-2 main protease visualized by room-temperature X-ray crystallography. Iucrj, 8, 2021
7N51	Structure of a bacterial gasdermin from Vitiosangium sp. 分子名称: Gasdermin 著者 Johnson, A.G, Kranzusch, P.J. 登録日 2021-06-04 公開日 2021-06-16 最終更新日 2022-01-26 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Bacterial gasdermins reveal an ancient mechanism of cell death. Science, 375, 2022
7NJA	14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1006 分子名称: 14-3-3 protein sigma, CHLORIDE ION, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... 著者 Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. 登録日 2021-02-16 公開日 2021-06-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
5HRV	Crystal structure of the fifth bromodomain of human PB1 in complex with 1-ethylisochromeno[3,4-c]pyrazol-5(2H)-one) compound 分子名称: 1,2-ETHANEDIOL, 1-ethylisochromeno[3,4-c]pyrazol-5(3H)-one, Protein polybromo-1 著者 Tallant, C, Myrianthopoulos, V, Gaboriaud-Kolar, N, Newman, J.A, Picaud, S, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Mikros, E, Knapp, S. 登録日 2016-01-24 公開日 2016-10-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Discovery and Optimization of a Selective Ligand for the Switch/Sucrose Nonfermenting-Related Bromodomains of Polybromo Protein-1 by the Use of Virtual Screening and Hydration Analysis. J.Med.Chem., 59, 2016
7NLY	Crystal structure of Mycobacterium tuberculosis ArgB in complex with 2-Chlorobenzimidazole. 分子名称: 2-chloranyl-1~{H}-benzimidazole, Acetylglutamate kinase, SULFATE ION 著者 Mendes, V, Thomas, S.E, Cory-Wright, J, Blundell, T.L. 登録日 2021-02-22 公開日 2021-06-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.246 Å) 主引用文献 A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis Comput Struct Biotechnol J, 19, 2021

<161162163164165166167168169170171172173174175176>