7N89
Room-temperature X-ray structure of SARS-CoV-2 main protease C145A mutant in complex with substrate Ac-SAVLQSGF-CONH2
Summary for 7N89
| Entry DOI | 10.2210/pdb7n89/pdb |
| Descriptor | 3C-like proteinase, ACE-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-NH2 (3 entities in total) |
| Functional Keywords | cysteine protease, c145a mutant, homodimer, hydrolase |
| Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) More |
| Total number of polymer chains | 4 |
| Total formula weight | 69250.83 |
| Authors | Kovalevsky, A.,Kneller, D.W.,Coates, L. (deposition date: 2021-06-14, release date: 2021-06-23, Last modification date: 2023-10-18) |
| Primary citation | Kneller, D.W.,Zhang, Q.,Coates, L.,Louis, J.M.,Kovalevsky, A. Michaelis-like complex of SARS-CoV-2 main protease visualized by room-temperature X-ray crystallography. Iucrj, 8:973-979, 2021 Cited by PubMed: 34804549DOI: 10.1107/S2052252521010113 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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