PDB: 243911 件ウェブページステータス検索Chemie searchBIRD

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5WBS	Crystal structure of Frizzled-7 CRD with an inhibitor peptide Fz7-21 分子名称: Frizzled-7,inhibitor peptide Fz7-21 著者 Nile, A.H, Mukund, S, Hannoush, R.N, Wang, W. 登録日 2017-06-29 公開日 2018-04-18 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.88 Å) 主引用文献 A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells. Nat. Chem. Biol., 14, 2018
5W9J	MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4 分子名称: G4 VH, G4 VL, Spike glycoprotein 著者 Pallesen, J, Ward, A.B. 登録日 2017-06-23 公開日 2017-08-16 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5WCC	Crystal structure of the broadly neutralizing Influenza A antibody VRC 315 02-1F07 Fab. 分子名称: GLYCEROL, POLYETHYLENE GLYCOL (N=34), SULFATE ION, ... 著者 Joyce, M.G, Andrews, S.F, Mascola, J.R, McDermott, A.B, Kwong, P.D. 登録日 2017-06-29 公開日 2017-12-13 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.461 Å) 主引用文献 Preferential induction of cross-group influenza A hemagglutinin stem-specific memory B cells after H7N9 immunization in humans. Sci Immunol, 2, 2017
5WCW	Phosphotriesterase variant S3 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase, ... 著者 Miton, C.M, Campbell, E.C, Jackson, C.J, Tokuriki, N. 登録日 2017-07-02 公開日 2019-01-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.457 Å) 主引用文献 Phosphotriesterase variant S4 To Be Published
6D96	Structure of influenza neuraminidase from strain A/BrevigMission/1/1918(H1N1) expressed in HEK-293E cells 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Campbell, A.C, Krause, K.L, Tanner, J.J. 登録日 2018-04-27 公開日 2019-05-01 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Optimisation of neuraminidase expression by HEK-293E cells for use in structural biology To Be Published
5WB1	Ligand-free US28 with stabilizing intracellular nanobody 分子名称: Envelope protein US28, nanobody 7 fusion protein 著者 Jude, K.M, Burg, J.S, Garcia, K.C. 登録日 2017-06-27 公開日 2018-06-13 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (3.508 Å) 主引用文献 Viral GPCR US28 can signal in response to chemokine agonists of nearly unlimited structural degeneracy. Elife, 7, 2018
5WBA	Peroxide Activation Regulated by Hydrogen Bonds within Artificial Cu Proteins - WT 分子名称: ACETATE ION, COPPER (II) ION, SULFATE ION, ... 著者 Mann, S.I, Heinisch, T, Ward, T.R, Borovik, A.S. 登録日 2017-06-28 公開日 2017-11-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Peroxide Activation Regulated by Hydrogen Bonds within Artificial Cu Proteins. J. Am. Chem. Soc., 139, 2017
5WFE	Cas1-Cas2-IHF-DNA holo-complex 分子名称: CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (28-MER), ... 著者 Wright, A.V, Liu, J.J, Nogales, E, Doudna, J.A. 登録日 2017-07-11 公開日 2017-08-02 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.64 Å) 主引用文献 Structures of the CRISPR genome integration complex. Science, 357, 2017
5WEK	GluA2 bound to antagonist ZK and GSG1L in digitonin, state 1 分子名称: Chimera of Glutamate receptor 2,Germ cell-specific gene 1-like protein, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid 著者 Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I. 登録日 2017-07-10 公開日 2017-08-02 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Channel opening and gating mechanism in AMPA-subtype glutamate receptors. Nature, 549, 2017
5WGT	Crystal Structure of MalA' H253A, premalbrancheamide complex 分子名称: (5aS,12aS,13aS)-12,12-dimethyl-2,3,11,12,12a,13-hexahydro-1H,5H,6H-5a,13a-(epiminomethano)indolizino[7,6-b]carbazol-14-one, CADMIUM ION, CHLORIDE ION, ... 著者 Fraley, A.E, Smith, J.L. 登録日 2017-07-14 公開日 2017-08-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.093 Å) 主引用文献 Function and Structure of MalA/MalA', Iterative Halogenases for Late-Stage C-H Functionalization of Indole Alkaloids. J. Am. Chem. Soc., 139, 2017
5WFI	X-ray structure of MHV PLP2 (Cys1716Ser) catalytic mutant in complex with free ubiquitin 分子名称: FORMIC ACID, GLYCEROL, Ubiquitin, ... 著者 Mesecar, A.D, Chen, Y. 登録日 2017-07-12 公開日 2018-08-01 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.851 Å) 主引用文献 X-ray structure of MHV PLP2 (Cys1716Ser) catalytic mutant in complex with free ubiquitin To Be Published
5WFS	70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C4) 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Fislage, M, Frank, J. 登録日 2017-07-12 公開日 2018-05-02 最終更新日 2025-02-12 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A. Nucleic Acids Res., 46, 2018
5WHR	Discovery of a novel and selective IDO-1 inhibitor PF-06840003 and its characterization as a potential clinical candidate. 分子名称: (3R)-3-(5-fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione, Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE 著者 Greasley, S.E, Kaiser, S.E, Feng, J.L, Stewart, A. 登録日 2017-07-18 公開日 2017-12-27 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Discovery of a Novel and Selective Indoleamine 2,3-Dioxygenase (IDO-1) Inhibitor 3-(5-Fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione (EOS200271/PF-06840003) and Its Characterization as a Potential Clinical Candidate. J. Med. Chem., 60, 2017
7RJR	Crystal structure of human Bromodomain containing protein 4 (BRD4) in complex with BCLTF1 分子名称: 1,2-ETHANEDIOL, Bcl-2-associated transcription factor 1, Bromodomain-containing protein 4, ... 著者 Fedorov, E, Islam, K, Ghosh, A. 登録日 2021-07-21 公開日 2022-08-03 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Uncovering the Bromodomain Interactome using Site-Specific Azide-Acetyllysine Photochemistry, Proteomic Profiling and Structural Characterization To Be Published
7RJQ	Crystal structure of human Bromodomain containing protein 4 (BRD4) in complex with ILF3 分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, CHLORIDE ION, ... 著者 Fedorov, E, Islam, K, Ghosh, A. 登録日 2021-07-21 公開日 2022-08-03 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Uncovering the Bromodomain Interactome using Site-Specific Azide-Acetyllysine Photochemistry, Proteomic Profiling and Structural Characterization To Be Published
7RJO	Crystal structure of human Bromodomain containing protein 4 (BRD4) in complex with hnRNPK 分子名称: ACETATE ION, Bromodomain-containing protein 4, GLYCEROL, ... 著者 Fedorov, E, Islam, K, Ghosh, A. 登録日 2021-07-21 公開日 2022-08-03 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Uncovering the Bromodomain Interactome using Site-Specific Azide-Acetyllysine Photochemistry, Proteomic Profiling and Structural Characterization Biorxiv, 2021
5WIH	Structure of New Delhi Metallo-Beta-lactamase 12 (NDM-12) 分子名称: Metallo-beta-lactamase NDM-12, ZINC ION 著者 VanPelt, J, Williams, C, Page, R.C. 登録日 2017-07-19 公開日 2017-10-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Clinical Variants of New Delhi Metallo-beta-Lactamase Are Evolving To Overcome Zinc Scarcity. Acs Infect Dis., 3, 2017
5WK3	CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CCL17 AND M116 FAB 分子名称: C-C motif chemokine 17, GLYCEROL, M116 HEAVY CHAIN, ... 著者 Teplyakov, A, Obmolova, G, Gilliland, G.L. 登録日 2017-07-24 公開日 2017-12-20 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural insights into chemokine CCL17 recognition by antibody M116. Biochem Biophys Rep, 13, 2018
7RJL	Crystal structure of human Bromodomain containing protein 3 (BRD3) in complex with SHMT 分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 3, GLYCEROL, ... 著者 Fedorov, E, Islam, K, Ghosh, A. 登録日 2021-07-21 公開日 2022-08-03 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Uncovering the Bromodomain Interactome using Site-Specific Azide-Acetyllysine Photochemistry, Proteomic Profiling and Structural Characterization Biorxiv, 2021
5WKR	Crystal structure of chalcone isomerase engineered from ancestral inference complexed with naringenin (ancCC) 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Engineered Chalcone Isomerase ancCC, ... 著者 Burke, J.R, Kaltenbach, M, Tawfik, D.S, Noel, J.P. 登録日 2017-07-25 公開日 2018-05-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Evolution of chalcone isomerase from a noncatalytic ancestor. Nat. Chem. Biol., 14, 2018
7RJM	Crystal structure of human Bromodomain containing protein 3 (BRD3) in complex with ILF3 分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 3, Interleukin enhancer-binding factor 3 著者 Fedorov, E, Islam, K, Ghosh, A. 登録日 2021-07-21 公開日 2022-08-03 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Uncovering the Bromodomain Interactome using Site-Specific Azide-Acetyllysine Photochemistry, Proteomic Profiling and Structural Characterization Biorxiv, 2021
7RJK	Crystal structure of human Bromodomain containing protein 3 (BRD3) in complex with hnRNPK 分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 3, GLYCEROL, ... 著者 Fedorov, E, Islam, K, Ghosh, A. 登録日 2021-07-21 公開日 2022-08-03 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Uncovering the Bromodomain Interactome using Site-Specific Azide-Acetyllysine Photochemistry, Proteomic Profiling and Structural Characterization Biorxiv, 2021
5WKP	Crystal Structure of the Human mitochondrial Cysteine Desulfurase in complex with ISD11 and Iron-Sulfur Cluster Scaffold Protein ISCU1, and E. coli ACP1 protein at 3.15A 分子名称: Acyl carrier protein, Cysteine desulfurase, mitochondrial, ... 著者 Boniecki, M.T, Cygler, M. 登録日 2017-07-25 公開日 2017-11-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex. Nat Commun, 8, 2017
5WL4	Crystal structure of chalcone isomerase engineered from ancestral inference (ancR3) 分子名称: Engineered Chalcone Isomerase ancR3, FORMIC ACID 著者 Burke, J.R, Kaltenbach, M, Tawfik, D.S, Noel, J.P. 登録日 2017-07-25 公開日 2018-05-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Evolution of chalcone isomerase from a noncatalytic ancestor. Nat. Chem. Biol., 14, 2018
5LFU	Myelin-associated glycoprotein (MAG) glycosylated and lysine-methylated full extracellular domain 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Myelin-associated glycoprotein, ... 著者 Pronker, M.F, Janssen, B.J.C. 登録日 2016-07-04 公開日 2016-12-14 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (4.3 Å) 主引用文献 Structural basis of myelin-associated glycoprotein adhesion and signalling. Nat Commun, 7, 2016

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