PDB: 12060 件ウェブページステータス検索Chemie searchBIRD

---

3LLU	Crystal structure of the nucleotide-binding domain of Ras-related GTP-binding protein C 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related GTP-binding protein C, ... 著者 Nedyalkova, L, Tempel, W, Tong, Y, Crombet, L, Zhong, N, Guan, X, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) 登録日 2010-01-29 公開日 2010-02-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of the nucleotide-binding domain of Ras-related GTP-binding protein C to be published
4UOE	Crystal Structure of Plasmodium Falciparum Spermidine Synthase in Complex with 5'-Deoxy-5'-Methylioadenosine and 4-Aminomethylaniline 分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 4-(aminomethyl)aniline, 5'-DEOXY-5'-METHYLTHIOADENOSINE, ... 著者 Sprenger, J, Halander, J.C, Svensson, B, Al-Karadaghi, S, Person, L. 登録日 2014-06-03 公開日 2014-10-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Three-Dimensional Structures of Plasmodium Falciparum Spermidine Synthase with Bound Inhibitors Suggest New Strategies for Drug Design. Acta Crystallogr.,Sect.D, 71, 2015
3LX9	Interconversion of Human Lysosomal Enzyme Specificities 分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, ... 著者 Tomasic, I.B, Metcalf, M.C, Guce, A.I, Clark, N.E, Garman, S.C. 登録日 2010-02-25 公開日 2010-05-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Interconversion of the specificities of human lysosomal enzymes associated with Fabry and Schindler diseases. J.Biol.Chem., 285, 2010
3LSL	Piracetam bound to the ligand binding domain of GluA2 (flop form) 分子名称: 2-(2-oxopyrrolidin-1-yl)acetamide, GLUTAMIC ACID, Glutamate receptor 2, ... 著者 Ahmed, A.H, Oswald, R.E. 登録日 2010-02-12 公開日 2010-03-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.122 Å) 主引用文献 Piracetam Defines a New Binding Site for Allosteric Modulators of alpha-Amino-3-hydroxy-5-methyl-4-isoxazole-propionic Acid (AMPA) Receptors. J.Med.Chem., 53, 2010
4UPJ	HUMAN IMMUNODEFICIENCY VIRUS TYPE 2 PROTEASE MUTANT WITH LYS 57 REPLACED BY LEU (K57L) COMPLEX WITH U097410 [4-HYDROXY-3-[1-[3-[[[[(TERT-BUTYLOXYCARBONYL) AMINOMETHYL]CARBONYL]AMINO]PHENYL]PROPYL]COUMARIN 分子名称: ({3-[1-(4-HYDROXY-2-OXO-2H-CHROMEN-3-YL)-PROPYL]-PHENYLCARBAMOYL}-METHYL)-CARBAMIC ACID TERT-BUTYL ESTER, HIV-2 PROTEASE 著者 Watenpaugh, K.D, Mulichak, A.M, Janakiraman, M.N. 登録日 1996-03-04 公開日 1996-10-14 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure-based design of novel HIV protease inhibitors: carboxamide-containing 4-hydroxycoumarins and 4-hydroxy-2-pyrones as potent nonpeptidic inhibitors. J.Med.Chem., 38, 1995
3LYF	Crystal Structure of the Rift Valley Fever Virus Nucleocapsid Protein 分子名称: GLYCEROL, Nucleocapsid protein 著者 Raymond, D.D, Smith, J.L. 登録日 2010-02-26 公開日 2010-06-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Structure of the Rift Valley fever virus nucleocapsid protein reveals another architecture for RNA encapsidation. Proc.Natl.Acad.Sci.USA, 107, 2010
3LXA	Interconversion of Human Lysosomal Enzyme Specificities 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, ... 著者 Tomasic, I.B, Metcalf, M.C, Guce, A.I, Clark, N.E, Garman, S.C. 登録日 2010-02-25 公開日 2010-05-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.04 Å) 主引用文献 Interconversion of the specificities of human lysosomal enzymes associated with Fabry and Schindler diseases. J.Biol.Chem., 285, 2010
4UCP	CRYSTAL STRUCTURE OF LEISHMANIA MAJOR N-MYRISTOYLTRANSFERASE (NMT) WITH BOUND MYRISTOYL-COA AND A FRAGMENT 分子名称: GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, N-methyl-1-[3-(morpholin-4-ylmethyl)phenyl]methanamine, TETRADECANOYL-COA 著者 Robinson, D.A, Wyatt, P.G. 登録日 2014-12-04 公開日 2015-05-13 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Identification and Structure Solution of Fragment Hits Against Kinetoplastid N-Myristoyltransferase Acta Crystallogr.,Sect.F, 71, 2015
4UCN	CRYSTAL STRUCTURE OF LEISHMANIA MAJOR N-MYRISTOYLTRANSFERASE (NMT) WITH BOUND MYRISTOYL-COA AND A FRAGMENT 分子名称: 2-PIPERAZIN-1-YL-ANILINE, GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, TETRADECANOYL-COA 著者 Robinson, D.A, Wyatt, P.G. 登録日 2014-12-04 公開日 2015-05-13 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Identification and Structure Solution of Fragment Hits Against Kinetoplastid N-Myristoyltransferase Acta Crystallogr.,Sect.F, 71, 2015
3LXR	Shigella IpgB2 in complex with human RhoA and GDP (complex C) 分子名称: GUANOSINE-5'-DIPHOSPHATE, IpgB2, SULFATE ION, ... 著者 Klink, B.U, Barden, S, Heidler, T.V, Borchers, C, Ladwein, M, Stradal, T.E.B, Rottner, K, Heinz, D.W. 登録日 2010-02-25 公開日 2010-03-31 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Structure of Shigella IPGB2 in complex with human RhoA: Implications for the mechanism of bacterial GEF-mimicry J.Biol.Chem., 285, 2010
3LXC	Interconversion of Human Lysosomal Enzyme Specificities 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, GLYCEROL, ... 著者 Tomasic, I.B, Metcalf, M.C, Guce, A.I, Clark, N.E, Garman, S.C. 登録日 2010-02-25 公開日 2010-05-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Interconversion of the specificities of human lysosomal enzymes associated with Fabry and Schindler diseases. J.Biol.Chem., 285, 2010
3LWB	Crystal Structure of apo D-alanine:D-alanine Ligase (Ddl) from Mycobacterium tuberculosis 分子名称: D-alanine--D-alanine ligase, NITRATE ION 著者 Bruning, J.B, Murillo, A.C, Chacon, O, Barletta, R.G, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) 登録日 2010-02-23 公開日 2010-03-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of the Mycobacterium tuberculosis D-Alanine:D-Alanine Ligase, a Target of the Antituberculosis Drug D-Cycloserine. Antimicrob.Agents Chemother., 55, 2011
3LXB	Interconversion of Human Lysosomal Enzyme Specificities 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, ... 著者 Tomasic, I.B, Metcalf, M.C, Guce, A.I, Clark, N.E, Garman, S.C. 登録日 2010-02-25 公開日 2010-05-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Interconversion of the specificities of human lysosomal enzymes associated with Fabry and Schindler diseases. J.Biol.Chem., 285, 2010
3M3F	PEPA bound to the ligand binding domain of GluA3 (flop form) 分子名称: 2-[2,6-difluoro-4-({2-[(phenylsulfonyl)amino]ethyl}sulfanyl)phenoxy]acetamide, GLUTAMIC ACID, Glutamate receptor 3, ... 著者 Ahmed, A.H, Ptak, C.P, Oswald, R.E. 登録日 2010-03-09 公開日 2010-03-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Molecular mechanism of flop selectivity and subsite recognition for an AMPA receptor allosteric modulator: structures of GluA2 and GluA3 in complexes with PEPA. Biochemistry, 49, 2010
3M91	Crystal structure of the prokaryotic ubiquitin-like protein (Pup) complexed with the amino terminal coiled coil of the Mycobacterium tuberculosis proteasomal ATPase Mpa 分子名称: Prokaryotic ubiquitin-like protein pup, Proteasome-associated ATPase 著者 Wang, T, Li, H. 登録日 2010-03-19 公開日 2010-10-27 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Binding-induced folding of prokaryotic ubiquitin-like protein on the Mycobacterium proteasomal ATPase targets substrates for degradation. Nat.Struct.Mol.Biol., 17, 2010
3MAU	Crystal structure of StSPL in complex with phosphoethanolamine 分子名称: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, PHOSPHATE ION, sphingosine-1-phosphate lyase, ... 著者 Bourquin, F, Grutter, M.G, Capitani, G. 登録日 2010-03-24 公開日 2010-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid Metabolism. Structure, 18, 2010
3MCY	Crystal structure of FimH lectin domain bound to biphenyl mannoside meta-methyl ester. 分子名称: CALCIUM ION, CHLORIDE ION, FimH, ... 著者 Ford, B.A, Hultgren, S.J. 登録日 2010-03-29 公開日 2010-06-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure-based drug design and optimization of mannoside bacterial FimH antagonists. J.Med.Chem., 53, 2010
3MKJ	Methionine gamma-lyase from Citrobacter freundii with pyridoximine-5'-phosphate 分子名称: Methionine gamma-lyase, [5-hydroxy-4-(iminomethyl)-6-methyl-pyridin-3-yl]methyl dihydrogen phosphate 著者 Revtovich, S.V, Nikulin, A.D, Morozova, E.A, Demidkina, T.V. 登録日 2010-04-15 公開日 2010-08-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Exploring methionine gamma-lyase structure-function relationship via microspectrophotometry and X-ray crystallography Biochim.Biophys.Acta, 1814, 2011
3MKT	Structure of a Cation-bound Multidrug and Toxin Compound Extrusion (MATE) transporter 分子名称: Multi antimicrobial extrusion protein (Na(+)/drug antiporter) MATE-like MDR efflux pump 著者 He, X, Szewczyk, P, Karyakin, A, Evin, M, Hong, W.-X, Zhang, Q, Chang, G. 登録日 2010-04-15 公開日 2010-09-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.65 Å) 主引用文献 Structure of a cation-bound multidrug and toxic compound extrusion transporter. Nature, 467, 2010
4UV8	LSD1(KDM1A)-CoREST in complex with 1-Benzyl-Tranylcypromine 分子名称: LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, REST COREPRESSOR 1, [[(2R,3S,4S)-5-[(4aS,10aS)-4a-[(1S)-3-azanylidene-1,4-diphenyl-butyl]-7,8-dimethyl-2,4-bis(oxidanylidene)-5,10a-dihydro-1H-benzo[g]pteridin-10-yl]-2,3,4-tris(oxidanyl)pentoxy]-oxidanyl-phosphoryl] [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate 著者 Vianello, P, Botrugno, O, Cappa, A, Ciossani, G, Dessanti, P, Mai, A, Mattevi, A, Meroni, G, Minucci, S, Thaler, F, Tortorici, M, Trifiro, P, Valente, S, Villa, M, Varasi, M, Mercurio, C. 登録日 2014-08-05 公開日 2014-09-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Synthesis, Biological Activity and Mechanistic Insights of 1-Substituted Cyclopropylamine Derivatives: A Novel Class of Irreversible Inhibitors of Histone Demethylase Kdm1A. Eur.J.Med.Chem., 86C, 2014
3MNO	Crystal structure of the agonist form of mouse glucocorticoid receptor stabilized by (A611V, F608S) mutations at 1.55A 分子名称: DEXAMETHASONE, GLYCEROL, Glucocorticoid receptor, ... 著者 Schoch, G.A, Seitz, T, Benz, J, Banner, D, Stihle, M, D'Arcy, B, Thoma, R, Sterner, R, Hennig, M, Ruf, A. 登録日 2010-04-22 公開日 2010-09-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Enhancing the stability and solubility of the glucocorticoid receptor ligand-binding domain by high-throughput library screening. J.Mol.Biol., 403, 2010
3MRV	Glycogen phosphorylase complexed with 3-hydroxybenzaldehyde-4-(beta-D-glucopyranosyl) thiosemicarbazone 分子名称: DIMETHYL SULFOXIDE, Glycogen phosphorylase, muscle form, ... 著者 Alexacou, K.-M. 登録日 2010-04-29 公開日 2011-01-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors Bioorg.Med.Chem., 18, 2010
4W96	Crystal structure of cross-linked tetragonal hen egg white lysozyme soaked with 5mM [Ru(CO)3Cl2]2 followed by the reaction in deoxy-myoglobin solution 分子名称: CHLORIDE ION, DIMETHYLFORMAMIDE, Lysozyme C, ... 著者 Tabe, H, Fujita, K, Abe, S, Tsujimoto, M, Kuchimaru, T, Kizaka-Kondo, S, Takano, M, Kitagawa, S, Ueno, T. 登録日 2014-08-27 公開日 2014-12-31 最終更新日 2020-01-29 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Preparation of a Cross-Linked Porous Protein Crystal Containing Ru Carbonyl Complexes as a CO-Releasing Extracellular Scaffold Inorg.Chem., 54, 2015
3MT8	Glycogen phosphorylase complexed with 4-chlorobenzaldehyde-4-(beta-D-glucopyranosyl)-thiosemicarbazone 分子名称: Glycogen phosphorylase, muscle form, N-({(2E)-2-[(4-chlorophenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine 著者 Alexacou, K.-M. 登録日 2010-04-30 公開日 2011-01-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors Bioorg.Med.Chem., 18, 2010
4UYL	Crystal structure of sterol 14-alpha demethylase (CYP51B) from a pathogenic filamentous fungus Aspergillus fumigatus in complex with VNI 分子名称: 14-ALPHA STEROL DEMETHYLASE, N-[(1R)-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethyl]-4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide, PROTOPORPHYRIN IX CONTAINING FE 著者 Hargrove, T.Y, Wawrzak, Z, Lepesheva, G.I. 登録日 2014-09-01 公開日 2015-08-19 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 Structure-Functional Characterization of Cytochrome P450 Sterol Alpha-Demethylase (Cyp51B) from Aspergillus Fumigatus and Molecular Basis for the Development of Antifungal Drugs J.Biol.Chem., 290, 2015

<159160161162163164165166167168169170171172173174>