PDB: 45459 件ウェブページステータス検索Chemie searchBIRD

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4G3Y	Crystal structure of TNF-alpha in complex with Infliximab Fab fragment 分子名称: Tumor necrosis factor, infliximab Fab H, infliximab Fab L 著者 Liang, S.Y, Dai, J.X, Guo, Y.J, Lou, Z.Y. 登録日 2012-07-15 公開日 2013-03-27 最終更新日 2013-08-07 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for treating tumor necrosis factor alpha (TNFalpha)-associated diseases with the therapeutic antibody infliximab J.Biol.Chem., 288, 2013
3LDL	Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with ATP 分子名称: 78 kDa glucose-regulated protein, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION 著者 Dokurno, P, Surgenor, A.E, Shaw, T, Macias, A.T, Massey, A.J, Williamson, D.S. 登録日 2010-01-13 公開日 2011-01-26 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Adenosine-Derived Inhibitors of 78 kDa Glucose Regulated Protein (Grp78) ATPase: Insights into Isoform Selectivity. J.Med.Chem., 54, 2011
4BNG	Crystal structure of S. aureus FabI in complex with NADP and 5-pentyl- 2-phenoxyphenol 分子名称: 5-PENTYL-2-PHENOXYPHENOL, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH], GLUTAMIC ACID, ... 著者 Schiebel, J, Chang, A, Bommineni, G.R, Tonge, P.J, Kisker, C. 登録日 2013-05-15 公開日 2013-06-05 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Rational Optimization of Drug-Target Residence Time: Insights from Inhibitor Binding to the S. Aureus Fabi Enzyme-Product Complex. Biochemistry, 52, 2013
4PCH	Structure of Human Polyomavirus 7 (HPyV7) VP1 pentamer 分子名称: GLYCEROL, VP1 著者 Stroh, L.J, Stehle, T. 登録日 2014-04-15 公開日 2014-08-06 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure analysis of the major capsid proteins of human polyomaviruses 6 and 7 reveals an obstructed sialic Acid binding site. J.Virol., 88, 2014
4BZ6	Crystal structure of Schistosoma mansoni HDAC8 complexed with SAHA 分子名称: DIMETHYLFORMAMIDE, GLYCEROL, HISTONE DEACETYLASE 8, ... 著者 Marek, M, Romier, C. 登録日 2013-07-24 公開日 2013-08-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Basis for the Inhibition of Histone Deacetylase 8 (Hdac8), a Key Epigenetic Player in the Blood Fluke Schistosoma Mansoni. Plos Pathog., 9, 2013
4C2Y	Human N-myristoyltransferase (NMT1) with Myristoyl-CoA co-factor 分子名称: CITRIC ACID, GLYCEROL, GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE 1, ... 著者 Thinon, E, Serwa, R.A, Brannigan, J.A, Brassat, U, Wright, M.H, Heal, W.P, Wilkinson, A.J, Mann, D.J, Tate, E.W. 登録日 2013-08-20 公開日 2014-10-01 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Global Profiling of Co- and Post-Translationally N-Myristoylated Proteomes in Human Cells. Nat.Commun., 5, 2014
3LRB	Structure of E. coli AdiC 分子名称: Arginine/agmatine antiporter 著者 Gao, X, Lu, F, Zhou, L, Shi, Y. 登録日 2010-02-10 公開日 2010-02-23 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3.61 Å) 主引用文献 Structure and mechanism of an amino acid antiporter Science, 324, 2009
4BWP	Structure of Drosophila Melanogaster PAN3 pseudokinase 分子名称: AMP PHOSPHORAMIDATE, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN-3 著者 Christie, M, Boland, A, Huntzinger, E, Weichenrieder, O, Izaurralde, E. 登録日 2013-07-03 公開日 2013-08-21 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structure of the Pan3 Pseudokinase Reveals the Basis for Interactions with the Pan2 Deadenylase and the Gw182 Proteins Mol.Cell, 51, 2013
4A1G	The crystal structure of the human Bub1 TPR domain in complex with the KI motif of Knl1 分子名称: MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1, PROTEIN CASC5 著者 Krenn, V, Wehenkel, A, Li, X, Santaguida, S, Musacchio, A. 登録日 2011-09-15 公開日 2012-02-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Analysis Reveals Features of the Spindle Checkpoint Kinase Bub1-Kinetochore Subunit Knl1 Interaction. J.Cell Biol., 196, 2012
4A1V	Co-Complex structure of NS3-4A protease with the optimized inhibitory peptide CP5-46A-4D5E 分子名称: CHLORIDE ION, CP5-46A-4D5E, NON-STRUCTURAL PROTEIN 4A, ... 著者 Schmelz, S, Kuegler, J, Collins, J, Heinz, D.W. 登録日 2011-09-20 公開日 2012-09-19 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 High Affinity Peptide Inhibitors of the Hepatitis C Virus Ns3-4A Protease Refractory to Common Resistant Mutants. J.Biol.Chem., 287, 2012
3LKH	Inhibitors of Hepatitis C Virus Polymerase: Synthesis and Characterization of Novel 6-Fluoro-N-[2-Hydroxy-1(S)-Benzamides 分子名称: 2-(2-{[(1S)-1-benzyl-2-hydroxyethyl]amino}-2-oxoethoxy)-N-butyl-6-fluoro-N-methylbenzamide, RNA-directed RNA polymerase 著者 Lesburg, C.A. 登録日 2010-01-27 公開日 2010-03-23 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Inhibitors of hepatitis C virus polymerase: synthesis and characterization of novel 2-oxy-6-fluoro-N-((S)-1-hydroxy-3-phenylpropan-2-yl)-benzamides. Bioorg.Med.Chem.Lett., 20, 2010
4DIA	CRYSTAL STRUCTURE OF THE D248N mutant of 2-PYRONE-4,6-DICARBOXYLIC ACID HYDROLASE FROM SPHINGOMONAS PAUCIMOBILIS complexed with substrate at pH 4.6 分子名称: 2-pyrone-4,6-dicarbaxylate hydrolase 著者 Malashkevich, V.N, Toro, R, Hobbs, M.E, Raushel, F.M, Almo, S.C. 登録日 2012-01-11 公開日 2012-10-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure and Catalytic Mechanism of LigI: Insight into the Amidohydrolase Enzymes of cog3618 and Lignin Degradation. Biochemistry, 51, 2012
4DT6	Co-crystal structure of eIF4E with inhibitor 分子名称: 1,2-ETHANEDIOL, 7-[2-(4-chlorophenoxy)ethyl]guanosine 5'-(dihydrogen phosphate), Eukaryotic translation initiation factor 4E, ... 著者 Min, X, Johnstone, S, Walker, N, Wang, Z. 登録日 2012-02-20 公開日 2012-04-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure-Guided Design, Synthesis, and Evaluation of Guanine-Derived Inhibitors of the eIF4E mRNA-Cap Interaction. J.Med.Chem., 55, 2012
4ALI	Crystal structure of S. aureus FabI in complex with NADP and triclosan (P1) 分子名称: ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH], GLUTAMIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Schiebel, J, Chang, A, Tonge, P.J, Kisker, C. 登録日 2012-03-04 公開日 2012-05-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Staphylococcus Aureus Fabi: Inhibition, Substrate Recognition and Potential Implications for in Vivo Essentiality Structure, 20, 2012
3LBY	Crystal structure of SMU.1697c, a putative methyltransferase from streptococcus mutans in complex with SAH 分子名称: Putative uncharacterized protein SMU.1697c, S-ADENOSYL-L-HOMOCYSTEINE 著者 Wang, K.-T, Nan, J, Su, X.-D. 登録日 2010-01-08 公開日 2011-01-12 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of SMU.1697c, a putative methyltransferase from streptococcus mutans in complex with SAH To be published
4DGR	Influenza Subtype 9 Neuraminidase Benzoic Acid Inhibitor Complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[2,2-bis(hydroxymethyl)-5-oxopyrrolidin-1-yl]-3-[(dipropylamino)methyl]benzoic acid, CALCIUM ION, ... 著者 Venkatramani, L, Johnson, E, Kolavi, G, Air, G.M, Brouillette, W, Mooers, B.H.M. 登録日 2012-01-26 公開日 2012-05-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.551 Å) 主引用文献 Crystal structure of a new benzoic acid inhibitor of influenza neuraminidase bound with a new tilt induced by overpacking sub-site C6. Bmc Struct.Biol., 12, 2012
4AL3	peptide deformylase (Co-form) with mercaptoethanol 分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, COBALT (II) ION, ... 著者 Palm, G.J, Hinrichs, W. 登録日 2012-02-29 公開日 2012-04-04 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 A Fret Enzyme-Based Probe for Monitoring Hydrogen Sulfide. Inorg.Chem., 51, 2012
4DHM	Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening 分子名称: 14-3-3 protein sigma, CHLORIDE ION, GLYCEROL, ... 著者 Thiel, P, Roeglin, L, Kohlbacher, O, Ottmann, C. 登録日 2012-01-30 公開日 2013-07-31 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein-protein interactions. Chem.Commun.(Camb.), 49, 2013
4DHT	Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening 分子名称: 14-3-3 PROTEIN SIGMA, CHLORIDE ION, GLYCEROL, ... 著者 Thiel, P, Roeglin, L, Kohlbacher, O, Ottmann, C. 登録日 2012-01-30 公開日 2013-07-31 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein-protein interactions. Chem.Commun.(Camb.), 49, 2013
4AOZ	B. subtilis dUTPase YncF in complex with dU, PPi and Mg (P212121) 分子名称: 2'-DEOXYURIDINE, ACETATE ION, CHLORIDE ION, ... 著者 Timm, J, Garcia-Nafria, J, Harrison, C, Turkenburg, J.P, Wilson, K.S. 登録日 2012-03-30 公開日 2013-05-01 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Tying Down the Arm in Bacillus Dutpase: Structure and Mechanism Acta Crystallogr.,Sect.D, 69, 2013
3LSD	N-Domain of human adhesion/growth-regulatory galectin-9 分子名称: Galectin-9 著者 Ruiz, F.M, Romero, A. 登録日 2010-02-12 公開日 2010-05-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 N-domain of human adhesion/growth-regulatory galectin-9: preference for distinct conformers and non-sialylated N-glycans and detection of ligand-induced structural changes in crystal and solution. Int.J.Biochem.Cell Biol., 42, 2010
4A3S	Crystal structure of PFK from Bacillus subtilis 分子名称: 6-PHOSPHOFRUCTOKINASE 著者 Newman, J.A, Hewitt, L, Rodrigues, C, Solovyova, A.S, Harwood, C.R, Lewis, R.J. 登録日 2011-10-04 公開日 2012-08-15 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Dissection of the Network of Interactions that Links RNA Processing with Glycolysis in the Bacillus Subtilis Degradosome. J.Mol.Biol., 416, 2012
4P1G	Crystal structure of the Bateman domain of murine magnesium transporter CNNM2 bound to AMP 分子名称: ADENOSINE MONOPHOSPHATE, Metal transporter CNNM2 著者 Corral-Rodriguez, M.A, Stuiver, M, Abascal-Palacios, G, Diercks, T, Oyenarte, I, Ereno-Orbea, J, Encinar, J.A, Spiwok, V, Terashima, H, Accardi, A, Muller, D, Martinez-Cruz, L.A. 登録日 2014-02-26 公開日 2015-03-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.603 Å) 主引用文献 Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4 To Be Published
4P4R	Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between Allergic Hypersensitivity and Autoimmunity 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DP alpha 1 chain, ... 著者 Clayton, G.M, Crawford, F, Kappler, J.W. 登録日 2014-03-13 公開日 2014-07-16 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity. Cell, 158, 2014
3LU2	Structure of lmo2462, a Listeria monocytogenes amidohydrolase family putative dipeptidase 分子名称: Lmo2462 protein, ZINC ION 著者 Anderson, S.M, Wawrzak, Z, Onopriyenko, O, Hasseman, J, Edwards, A, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2010-02-16 公開日 2010-03-09 最終更新日 2018-01-31 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of lmo2462, a Listeria monocytogenes amidohydrolase family putative dipeptidase To be Published

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