5J0L
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![BU of 5j0l by Molmil](/molmil-images/mine/5j0l) | De novo design of protein homo-oligomers with modular hydrogen bond network-mediated specificity | 分子名称: | designed protein 3L6HC2_2 | 著者 | Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Boyken, S, Chen, Z, Groves, B, Langan, R.A, Oberdorfer, G, Ford, A, Gilmore, J, Xu, C, DiMaio, F, Seelig, G. | 登録日 | 2016-03-28 | 公開日 | 2016-07-06 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity. Science, 352, 2016
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3C1G
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![BU of 3c1g by Molmil](/molmil-images/mine/3c1g) | Substrate binding, deprotonation and selectivity at the periplasmic entrance of the E. coli ammonia channel AmtB | 分子名称: | ACETATE ION, Ammonia channel, SULFATE ION | 著者 | Javelle, A, Kostrewa, D, Lupo, D, Winkler, F.K. | 登録日 | 2008-01-23 | 公開日 | 2008-03-18 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Substrate binding, deprotonation, and selectivity at the periplasmic entrance of the Escherichia coli ammonia channel AmtB. Proc.Natl.Acad.Sci.Usa, 105, 2008
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5ITX
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![BU of 5itx by Molmil](/molmil-images/mine/5itx) | Crystal Structure of Human NEIL1(P2G R242K) bound to duplex DNA containing Thymine Glycol | 分子名称: | DNA (26-MER), Endonuclease 8-like 1 | 著者 | Zhu, C, Lu, L, Zhang, J, Yue, Z, Song, J, Zong, S, Liu, M, Stovicek, O, Gao, Y, Yi, C. | 登録日 | 2016-03-17 | 公開日 | 2016-07-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Tautomerization-dependent recognition and excision of oxidation damage in base-excision DNA repair Proc.Natl.Acad.Sci.USA, 113, 2016
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4UX1
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![BU of 4ux1 by Molmil](/molmil-images/mine/4ux1) | Cryo-EM structure of antagonist-bound E2P gastric H,K-ATPase (SCH.E2. AlF) | 分子名称: | POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1, POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA | 著者 | Abe, K, Tani, K, Fujiyoshi, Y. | 登録日 | 2014-08-18 | 公開日 | 2014-09-17 | 最終更新日 | 2014-11-12 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (8 Å) | 主引用文献 | Systematic Comparison of Molecular Conformations of H+,K+-ATPase Reveals an Important Contribution of the A-M2 Linker for the Luminal Gating. J.Biol.Chem., 289, 2014
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3BR5
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3C49
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![BU of 3c49 by Molmil](/molmil-images/mine/3c49) | Human poly(ADP-ribose) polymerase 3, catalytic fragment in complex with an inhibitor KU0058948 | 分子名称: | 4-[3-(1,4-diazepan-1-ylcarbonyl)-4-fluorobenzyl]phthalazin-1(2H)-one, Poly(ADP-ribose) polymerase 3 | 著者 | Lehtio, L, Karlberg, T, Arrowsmith, C.H, Berglund, H, Bountra, C, Busam, R, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Helleday, T, Herman, M.D, Johansson, A, Johansson, I, Kallas, A, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Svensson, L, Thorsell, A.G, Tresaugues, L, Van den Berg, S, Welin, M, Weigelt, J, Structural Genomics Consortium (SGC) | 登録日 | 2008-01-29 | 公開日 | 2008-02-12 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis for inhibitor specificity in human poly(ADP-ribose) polymerase-3. J.Med.Chem., 52, 2009
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5XTM
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3C4H
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![BU of 3c4h by Molmil](/molmil-images/mine/3c4h) | Human poly(ADP-ribose) polymerase 3, catalytic fragment in complex with an inhibitor DR2313 | 分子名称: | 2-methyl-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]pyrimidin-4-one, DIMETHYL SULFOXIDE, Poly(ADP-ribose) polymerase 3 | 著者 | Lehtio, L, Collins, R, Arrowsmith, C.H, Berglund, H, Bountra, C, Busam, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Herman, M.D, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Svensson, L, Thorsell, A.G, Tresaugues, L, Van den Berg, S, Welin, M, Weigelt, J, Structural Genomics Consortium (SGC) | 登録日 | 2008-01-30 | 公開日 | 2008-02-12 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for inhibitor specificity in human poly(ADP-ribose) polymerase-3. J.Med.Chem., 52, 2009
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3C4S
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![BU of 3c4s by Molmil](/molmil-images/mine/3c4s) | Crystal structure of the Ssl0352 protein from Synechocystis sp. Northeast Structural Genomics Consortium target SgR42 | 分子名称: | Ssl0352 protein | 著者 | Vorobiev, S.M, Chen, Y, Seetharaman, J, Wang, D, Maglaqui, M, Janjua, H, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2008-01-30 | 公開日 | 2008-02-12 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of the Ssl0352 protein from Synechocystis sp. To be Published
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5JBJ
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5XVO
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![BU of 5xvo by Molmil](/molmil-images/mine/5xvo) | E. fae Cas1-Cas2/prespacer/target ternary complex revealing DNA sampling and half-integration states | 分子名称: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (28-MER), ... | 著者 | Xiao, Y, Ng, S, Nam, K.H, Ke, A. | 登録日 | 2017-06-28 | 公開日 | 2017-10-04 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | How type II CRISPR-Cas establish immunity through Cas1-Cas2-mediated spacer integration. Nature, 550, 2017
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5XWG
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5JBV
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5JC3
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5JCF
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3BOJ
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![BU of 3boj by Molmil](/molmil-images/mine/3boj) | Carbonic anhydrase from marine diatom Thalassiosira weissflogii- cadmium bound domain 1 without bound metal (CDCA1-R1) | 分子名称: | ACETATE ION, Cadmium-specific carbonic anhydrase | 著者 | Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M. | 登録日 | 2007-12-17 | 公開日 | 2008-01-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms. Nature, 452, 2008
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5JD3
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![BU of 5jd3 by Molmil](/molmil-images/mine/5jd3) | Crystal structure of LAE5, an alpha/beta hydrolase enzyme from the metagenome of Lake Arreo, Spain | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, LAE5, ... | 著者 | Stogios, P.J, Xu, X, Nocek, B, Cui, H, Yim, V, Martinez-Martinez, M, Alcaide, M, Ferrer, M, Savchenko, A. | 登録日 | 2016-04-15 | 公開日 | 2016-05-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | To be published To Be Published
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5XXF
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![BU of 5xxf by Molmil](/molmil-images/mine/5xxf) | Crystal structure of Poz1, Tpz1 and Rap1 | 分子名称: | Protection of telomeres protein poz1, Protection of telomeres protein tpz1, Rap1, ... | 著者 | Xue, J, Chen, H, Wu, J, Lei, M. | 登録日 | 2017-07-03 | 公開日 | 2017-12-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structure of the fission yeast S. pombe telomeric Tpz1-Poz1-Rap1 complex. Cell Res., 27, 2017
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3BQD
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![BU of 3bqd by Molmil](/molmil-images/mine/3bqd) | Doubling the Size of the Glucocorticoid Receptor Ligand Binding Pocket by Deacylcortivazol | 分子名称: | 1-[(1R,2R,3aS,3bS,10aR,10bS,11S,12aS)-1,11-dihydroxy-2,5,10a,12a-tetramethyl-7-phenyl-1,2,3,3a,3b,7,10,10a,10b,11,12,12a-dodecahydrocyclopenta[5,6]naphtho[1,2-f]indazol-1-yl]-2-hydroxyethanone, Glucocorticoid receptor, Nuclear receptor coactivator 1 | 著者 | Xu, H.E. | 登録日 | 2007-12-20 | 公開日 | 2008-01-15 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Doubling the size of the glucocorticoid receptor ligand binding pocket by deacylcortivazol. Mol.Cell.Biol., 28, 2008
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5JEV
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3C3E
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![BU of 3c3e by Molmil](/molmil-images/mine/3c3e) | Crystal structure of 2-phospho-(S)-lactate transferase from Methanosarcina mazei in complex with Fo and GDP. Northeast Structural Genomics Consortium target MaR46 | 分子名称: | 1-deoxy-1-(8-hydroxy-2,4-dioxo-3,4-dihydropyrimido[4,5-b]quinolin-10(2H)-yl)-D-ribitol, 2-phospho-L-lactate transferase, GUANOSINE-5'-DIPHOSPHATE | 著者 | Forouhar, F, Abashidze, M, Xu, H, Grochowski, L.L, Seetharaman, J, Hussain, M, Kuzin, A.P, Chen, Y, Zhou, W, Xiao, R, Acton, T.B, Montelione, G.T, Galinier, A, White, R.H, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2008-01-28 | 公開日 | 2008-02-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Molecular insights into the biosynthesis of the f420 coenzyme. J.Biol.Chem., 283, 2008
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5JF0
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![BU of 5jf0 by Molmil](/molmil-images/mine/5jf0) | Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with tripeptide Met-Ala-Arg | 分子名称: | ACETATE ION, MET-ALA-ARG, NICKEL (II) ION, ... | 著者 | Fieulaine, S, Giglione, C, Meinnel, T. | 登録日 | 2016-04-19 | 公開日 | 2016-11-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
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5X6G
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![BU of 5x6g by Molmil](/molmil-images/mine/5x6g) | Crystal Structure of SMAD5-MH1/palindromic SBE DNA complex | 分子名称: | DNA (5'-D(P*AP*TP*CP*AP*GP*TP*CP*TP*AP*GP*AP*CP*AP*TP*A)-3'), DNA (5'-D(P*GP*TP*AP*TP*GP*TP*CP*TP*AP*GP*AP*CP*TP*GP*A)-3'), Mothers against decapentaplegic homolog 5, ... | 著者 | Chai, N, Wang, J, Wang, Z.X, Wu, J.W. | 登録日 | 2017-02-21 | 公開日 | 2017-03-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Structural basis for the Smad5 MH1 domain to recognize different DNA sequences. Nucleic Acids Res., 43, 2015
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5X6H
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![BU of 5x6h by Molmil](/molmil-images/mine/5x6h) | Crystal Structure of SMAD5-MH1/GC-BRE DNA complex | 分子名称: | DNA (5'-D(P*GP*TP*AP*TP*GP*GP*CP*GP*CP*CP*AP*TP*AP*C)-3'), Mothers against decapentaplegic homolog 5, ZINC ION | 著者 | Chai, N, Wang, J, Wang, Z.X, Wu, J.W. | 登録日 | 2017-02-22 | 公開日 | 2017-03-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural basis for the Smad5 MH1 domain to recognize different DNA sequences. Nucleic Acids Res., 43, 2015
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5X6M
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![BU of 5x6m by Molmil](/molmil-images/mine/5x6m) | Crystal Structure of SMAD5-MH1 in complex with a composite DNA sequence | 分子名称: | DNA (5'-D(P*AP*TP*CP*AP*GP*AP*CP*TP*GP*CP*CP*GP*GP*CP*AP*GP*TP*CP*TP*AP*TP*A)-3'), DNA (5'-D(P*TP*TP*AP*TP*AP*GP*AP*CP*TP*GP*CP*CP*GP*GP*CP*AP*GP*TP*CP*TP*GP*A)-3'), Mothers against decapentaplegic homolog 5, ... | 著者 | Chai, N, Wang, J, Wang, Z.X, Wu, J.W. | 登録日 | 2017-02-22 | 公開日 | 2017-03-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for the Smad5 MH1 domain to recognize different DNA sequences. Nucleic Acids Res., 43, 2015
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