PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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3HHC	Interferon-lambda is functionally an interferon but structurally related to the IL-10 family 分子名称: IODIDE ION, Interleukin-28B 著者 Gad, H.H, Hamming, O.J, Hartmann, R. 登録日 2009-05-15 公開日 2009-07-21 最終更新日 2018-01-24 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Interferon-{lambda} Is Functionally an Interferon but Structurally Related to the Interleukin-10 Family J.Biol.Chem., 284, 2009
5VKE	Open conformation of KcsA deep-inactivated 分子名称: (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, Antibody Heavy Chain, Antibody Light Chain, ... 著者 Cuello, L.G, Perozo, E, Cortes, D.M. 登録日 2017-04-21 公開日 2017-12-06 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 The gating cycle of a K+ channel at atomic resolution. Elife, 6, 2017
7LX2	Cryo-EM structure of ConSOSL.UFO.664 (ConS) in complex with bNAb PGT122 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Env glycoprotein gp160, ... 著者 Martin, G.M, Ward, A.B, Sattentau, Q.J. 登録日 2021-03-03 公開日 2022-03-09 最終更新日 2023-09-20 実験手法 ELECTRON MICROSCOPY (3.12 Å) 主引用文献 Profound structural conservation of chemically cross-linked HIV-1 envelope glycoprotein experimental vaccine antigens. Npj Vaccines, 8, 2023
4W8C	Crystal structure of the helical domain deleted form MsrA from Clostridium oremlandii 分子名称: GLYCINE, Peptide methionine sulfoxide reductase MsrA 著者 Lee, E.H, Hwang, K.Y, Kim, H.-Y. 登録日 2014-08-23 公開日 2015-07-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.7568 Å) 主引用文献 Essential role of the C-terminal helical domain in active site formation of selenoprotein MsrA from Clostridium oremlandii Plos One, 10, 2015
5VMY	Kaiso (ZBTB33) zinc finger DNA binding domain in complex with a hemi CpG-methylated DNA resembling the specific Kaiso binding sequence (KBS) 分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*CP*GP*CP*GP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*(5CM)P*GP*(5CM)P*GP*AP*AP*TP*AP*AP*CP*G)-3'), ... 著者 Nikolova, E.N, Stanfield, R.L, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E. 登録日 2017-04-28 公開日 2018-04-04 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.002 Å) 主引用文献 CH···O Hydrogen Bonds Mediate Highly Specific Recognition of Methylated CpG Sites by the Zinc Finger Protein Kaiso. Biochemistry, 57, 2018
4W9J	pVHL:EloB:EloC in complex with (2S,4R)-1-((S)-2-((S)-2-acetamido-4-methylpentanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (ligand 13) 分子名称: N-acetyl-L-leucyl-3-methyl-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide, Transcription elongation factor B polypeptide 1, Transcription elongation factor B polypeptide 2, ... 著者 Gadd, M.S, Galdeano, C, van Molle, I, Ciulli, A. 登録日 2014-08-27 公開日 2014-09-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-Guided Design and Optimization of Small Molecules Targeting the Protein-Protein Interaction between the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase and the Hypoxia Inducible Factor (HIF) Alpha Subunit with in Vitro Nanomolar Affinities. J.Med.Chem., 57, 2014
4W8N	The crystal structure of hemagglutinin from a swine influenza virus (A/swine/Missouri/2124514/2006) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin 著者 Yang, H, Carney, P.J, Tumpey, T.M, Stevens, J. 登録日 2014-08-25 公開日 2015-02-11 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Assessment of transmission, pathogenesis and adaptation of H2 subtype influenza viruses in ferrets. Virology, 477C, 2015
7LX3	Cryo-EM structure of EDC-crosslinked ConSOSL.UFO.664 (ConS-EDC) in complex with bNAb PGT122 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Env glycoprotein gp160, ... 著者 Martin, G.M, Ward, A.B, Sattentau, Q.J. 登録日 2021-03-03 公開日 2022-03-09 最終更新日 2023-09-20 実験手法 ELECTRON MICROSCOPY (3.45 Å) 主引用文献 Profound structural conservation of chemically cross-linked HIV-1 envelope glycoprotein experimental vaccine antigens. Npj Vaccines, 8, 2023
7LAW	crystal structure of GITR complex with GITR-L 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 18, Tumor necrosis factor receptor superfamily member 18 著者 Longenecker, K.L, Rogers, B, Bigelow, L, Judge, R.A, Alvarez, H. 登録日 2021-01-07 公開日 2022-03-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.752 Å) 主引用文献 An anti-PD-1-GITR-L bispecific agonist induces GITR clustering-mediated T cell activation for cancer immunotherapy. Nat Cancer, 3, 2022
5VNI	Crystal structure of Sec23a/Sec24a/Sec22 complexed with a C-terminal FA sorting motif 分子名称: C-terminal FA, Protein transport protein Sec23A, Protein transport protein Sec24A, ... 著者 Ma, W, Goldberg, J. 登録日 2017-04-30 公開日 2017-07-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.788 Å) 主引用文献 ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate. Elife, 6, 2017
6QLX	Cathepsin-K in complex with fluoro-oxa-azabicyclo[3.3.0]octanyl containing inhibitor 分子名称: Cathepsin K, ~{N}-[(2~{S})-1-[(3~{R},3~{a}~{R},6~{S},6~{a}~{S})-6-fluoranyl-3-oxidanyl-2,3,3~{a},5,6,6~{a}-hexahydrofuro[3,2-b]pyrrol-4-yl]-4-methyl-1-oxidanylidene-pentan-2-yl]-4-thiophen-2-yl-benzamide 著者 Derbyshire, D.J. 登録日 2019-02-01 公開日 2020-02-19 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Successful development of 3-oxohexahydrofuropyrrole amino acid amides as inhibitors of Cathepsin-K. To Be Published
3HIK	Structure of human Plk1-PBD in complex with PLHSpT 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Pentamer phosphopeptide, ... 著者 Wlodawer, A, Moulaei, T. 登録日 2009-05-20 公開日 2009-06-09 最終更新日 2017-11-01 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1. Nat.Struct.Mol.Biol., 16, 2009
3UQA	Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase with surface mutation A54E from Burkholderia pseudomallei complexed with FK506 分子名称: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-11-19 公開日 2011-12-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins. Antimicrob.Agents Chemother., 58, 2014
7LXM	Cryo-EM structure of ConM SOSIP.v7 (ConM) in complex with bNAb PGT122 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Env glycoprotein gp120, ... 著者 Martin, G.M, Ward, A.B, Sattentau, Q.J. 登録日 2021-03-04 公開日 2022-03-09 最終更新日 2023-09-20 実験手法 ELECTRON MICROSCOPY (3.41 Å) 主引用文献 Profound structural conservation of chemically cross-linked HIV-1 envelope glycoprotein experimental vaccine antigens. Npj Vaccines, 8, 2023
4WBE	Crystal structure of the HR-1 domain of human caprin-1 in the C121 space group 分子名称: Caprin-1 著者 Wu, Y, Zhu, J, Huang, X, Du, Z. 登録日 2014-09-03 公開日 2015-10-21 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystal structure of the HR-1 domain of human caprin-1 in the C121 space group To be published
4WBT	Crystal structure of histidinol-phosphate aminotransferase from Sinorhizobium meliloti in complex with pyridoxal-5'-phosphate 分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Shabalin, I.G, Bacal, P, Kowalska, A.K, Cooper, D.R, Stead, M, Hammonds, J, Ahmed, M, Hillerich, B.S, Bonanno, J, Seidel, R, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2014-09-03 公開日 2014-09-24 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of histidinol-phosphate aminotransferase from Sinorhizobium meliloti in complex with pyridoxal-5'-phosphate to be published
3UVE	Crystal structure of Carveol dehydrogenase ((+)-trans-carveol dehydrogenase) from Mycobacterium avium 分子名称: 1,2-ETHANEDIOL, Carveol dehydrogenase ((+)-trans-carveol dehydrogenase), NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-11-29 公開日 2011-12-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
4WCL	Crystal Structure of product bound Cell Shape Determinant protein Csd4 from Helicobacter pylori 分子名称: 2,6-DIAMINOPIMELIC ACID, Conserved hypothetical secreted protein, IODIDE ION, ... 著者 Chan, A.C, Murphy, M.E. 登録日 2014-09-05 公開日 2014-12-24 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Helical Shape of Helicobacter pylori Requires an Atypical Glutamine as a Zinc Ligand in the Carboxypeptidase Csd4. J.Biol.Chem., 290, 2015
7LXN	Cryo-EM structure of EDC-crosslinked ConM SOSIP.v7 (ConM-EDC) in complex with bNAb PGT122 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Env glycoprotein gp120, ... 著者 Martin, G.M, Ward, A.B, Sattentau, Q.J. 登録日 2021-03-04 公開日 2022-03-09 最終更新日 2023-09-20 実験手法 ELECTRON MICROSCOPY (3.85 Å) 主引用文献 Profound structural conservation of chemically cross-linked HIV-1 envelope glycoprotein experimental vaccine antigens. Npj Vaccines, 8, 2023
3HEI	Ligand Recognition by A-Class Eph Receptors: Crystal Structures of the EphA2 Ligand-Binding Domain and the EphA2/ephrin-A1 Complex 分子名称: Ephrin type-A receptor 2, Ephrin-A1 著者 Himanen, J.P, Goldgur, Y, Miao, H, Myshkin, E, Guo, H, Buck, M, Nguyen, M, Rajashankar, K.R, Wang, B, Nikolov, D.B. 登録日 2009-05-08 公開日 2009-06-30 最終更新日 2021-03-31 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex. Embo Rep., 10, 2009
4WBI	Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutations H230Q and H309Q 分子名称: 2',3'-cyclic-nucleotide 3'-phosphodiesterase 著者 Myllykoski, M, Raasakka, A, Kursula, P. 登録日 2014-09-03 公開日 2015-09-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase. Sci Rep, 5, 2015
3HG1	Germline-governed recognition of a cancer epitope by an immunodominant human T cell receptor 分子名称: Beta-2-microglobulin, CANCER/MART-1, GLYCEROL, ... 著者 Cole, D.K, Yuan, F, Rizkallah, P.J, Miles, J.J, Gostick, E, Price, D.A, Gao, G.F, Jakobsen, B.K, Sewell, A.K. 登録日 2009-05-13 公開日 2009-07-28 最終更新日 2014-04-09 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Germ line-governed recognition of a cancer epitope by an immunodominant human T-cell receptor. J.Biol.Chem., 284, 2009
5VQD	Beta-glucoside phosphorylase BglX 分子名称: Beta-glucoside phosphorylase BglX, GLYCEROL 著者 Patel, A, Mark, B.L. 登録日 2017-05-08 公開日 2018-01-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and mechanistic analysis of a beta-glycoside phosphorylase identified by screening a metagenomic library. J. Biol. Chem., 293, 2018
5VQK	X-ray co-structure of nuclear receptor ROR-gammat Ligand Binding Domain with a inverse agonist and SRC2 peptide 分子名称: 1-(4-fluorophenyl)-7-methoxy-N-{[4-(methylsulfamoyl)phenyl]methyl}-1H-pyrazolo[3,4-c]pyridine-4-carboxamide, Nuclear receptor ROR-gamma, SRC2 chimera 著者 Li, X. 登録日 2017-05-09 公開日 2018-05-16 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 X-ray co-structure of nuclear receptor ROR-gammat Ligand Binding Domain with a inverse agonist and SRC2 peptide To Be Published
4WBZ	tRNA-processing enzyme (apo form 2) 分子名称: Poly A polymerase 著者 Yamashita, S, Tomtia, K. 登録日 2014-09-04 公開日 2015-04-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Measurement of Acceptor-T Psi C Helix Length of tRNA for Terminal A76-Addition by A-Adding Enzyme. Structure, 23, 2015

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