PDB: 95574 件ウェブページステータス検索Chemie searchBIRD

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3D5Z	Crystal Structure Analysis of 1,5-alpha-arabinanase catalytic mutant (AbnBE201A) complexed to arabinotriose 分子名称: CALCIUM ION, Intracellular arabinanase, alpha-L-arabinofuranose-(1-5)-alpha-L-arabinofuranose-(1-5)-beta-L-arabinofuranose 著者 Alhassid, A, Ben David, A, Shoham, Y, Shoham, G. 登録日 2008-05-18 公開日 2009-04-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of an inverting GH 43 1,5-alpha-L-arabinanase from Geobacillus stearothermophilus complexed with its substrate Biochem.J., 422, 2009
6CUM	Crystal structure of a C-terminal proteolytic fragment of a protein annotated as an LAO/AO transport system ATPase but likely MeaB and MMAA-like GTPase from Mycobacterium smegmatis 分子名称: 1,2-ETHANEDIOL, LAO/AO transport system ATPase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-03-26 公開日 2018-04-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Ab initio structure solution of a proteolytic fragment using ARCIMBOLDO. Acta Crystallogr F Struct Biol Commun, 74, 2018
7AKM	Crystal structure of CHK1 kinase domain in complex with ATPyS 分子名称: 1,2-ETHANEDIOL, CITRIC ACID, MAGNESIUM ION, ... 著者 Day, M, Oliver, A.W, Pearl, L.H. 登録日 2020-10-01 公開日 2021-04-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Structural basis for recruitment of the CHK1 DNA damage kinase by the CLASPIN scaffold protein. Structure, 29, 2021
6HPV	Crystal structure of mouse fetuin-B 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Fetuin-B 著者 Fahrenkamp, D, Dietzel, E, de Sanctis, D, Jovine, L. 登録日 2018-09-22 公開日 2019-02-20 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of mammalian plasma fetuin-B and its mechanism of selective metallopeptidase inhibition. Iucrj, 6, 2019
4G3F	Crystal structure of murine NF-kappaB inducing kinase (NIK) bound to a 2-(aminothiazoly)phenol (cmp2) 分子名称: 3-{2-[(5-fluoro-2-hydroxyphenyl)amino]-1,3-thiazol-4-yl}benzonitrile, NF-kappa-beta-inducing kinase 著者 Hymowitz, S.G, de Leon-Boenig, G. 登録日 2012-07-13 公開日 2012-08-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.642 Å) 主引用文献 The crystal structure of the catalytic domain of the NF-kappaB inducing kinase reveals a narrow but flexible active site. Structure, 20, 2012
3D1K	R/T intermediate quaternary structure of an antarctic fish hemoglobin in an alpha(CO)-beta(pentacoordinate) state 分子名称: ACETYL GROUP, CARBON MONOXIDE, Hemoglobin subunit alpha-1, ... 著者 Vitagliano, L, Vergara, A, Bonomi, G, Merlino, A, Mazzarella, L. 登録日 2008-05-06 公開日 2008-08-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Spectroscopic and crystallographic characterization of a tetrameric hemoglobin oxidation reveals structural features of the functional intermediate relaxed/tense state. J.Am.Chem.Soc., 130, 2008
9F63	Crystal structure of Saccharomyces cerevisiae pH nine-sensitive protein 1 (PNS1) 分子名称: Protein PNS1 著者 Driller, J.H, Pedersen, B.P. 登録日 2024-04-30 公開日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.73 Å) 主引用文献 S. cerevisiae pH nine-sensitive protein 1 is not a choline transporter. To Be Published
3LZM	STRUCTURAL STUDIES OF MUTANTS OF T4 LYSOZYME THAT ALTER HYDROPHOBIC STABILIZATION 分子名称: T4 LYSOZYME 著者 Wilson, K, Faber, R, Dao-Pin, S, Matthews, B.W. 登録日 1989-05-01 公開日 1990-01-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural studies of mutants of T4 lysozyme that alter hydrophobic stabilization. J.Biol.Chem., 264, 1989
8X91	P/Q type calcium channel in complex with omega-conotoxin MVIIC 分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Yan, N, Li, Z, Cong, Y, Wu, T, Wang, T. 登録日 2023-11-29 公開日 2024-03-20 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.11 Å) 主引用文献 Structural basis for different omega-agatoxin IVA sensitivities of the P-type and Q-type Ca v 2.1 channels. Cell Res., 34, 2024
7ZMK	Structure of human MFAP4 in complex with the Fab fragment of the AS0326 monoclonal antibody 分子名称: CALCIUM ION, Light chain of AS0326, Microfibril-associated glycoprotein 4, ... 著者 Laursen, N.S, Andersen, G.R. 登録日 2022-04-19 公開日 2023-03-01 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 MFAP4-targeted immunotherapy inhibits retinal neovascularization and vascular leakage To Be Published
6W6G	The Mycobacterium tuberculosis ClpB disaggregase hexamer structure in conformation I in the presence of DnaK chaperone and a model substrate 分子名称: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... 著者 Yin, Y, Li, H. 登録日 2020-03-16 公開日 2021-03-17 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system. Cell Rep, 35, 2021
6W6H	The Mycobacterium tuberculosis ClpB disaggregase hexamer structure in conformation II in the presence of DnaK chaperone and a model substrate 分子名称: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... 著者 Yin, Y, Li, H. 登録日 2020-03-16 公開日 2021-05-26 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system. Cell Rep, 35, 2021
6W6E	The Mycobacterium tuberculosis ClpB disaggregase hexamer structure with a locally refined ClpB middle domain and a DnaK nucleotide binding domain 分子名称: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, Chaperone protein DnaK, ... 著者 Yin, Y, Li, H. 登録日 2020-03-16 公開日 2021-05-26 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system. Cell Rep, 35, 2021
6W6J	The Mycobacterium tuberculosis ClpB disaggregase hexamer structure with a locally refined N-terminal domain in the presence of DnaK chaperone and a model substrate 分子名称: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... 著者 Yin, Y, Li, H. 登録日 2020-03-17 公開日 2021-05-26 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system. Cell Rep, 35, 2021
6W6I	The Mycobacterium tuberculosis ClpB disaggregase hexamer structure in conformation T in the presence of DnaK chaperone and a model substrate 分子名称: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... 著者 Yin, Y, Li, H. 登録日 2020-03-17 公開日 2021-05-26 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system. Cell Rep, 35, 2021
6WGC	Atomic model of semi-attached mutant OCCM-DNA complex (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) 分子名称: Cell division control protein 6, DNA (41-MER), DNA replication licensing factor MCM3, ... 著者 Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C. 登録日 2020-04-05 公開日 2020-07-15 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6. Proc.Natl.Acad.Sci.USA, 117, 2020
8I0J	JB13GH39P28 mutant-D41G 分子名称: CHLORIDE ION, Glycoside hydrolase family 39 beta-xylosidase 著者 Zhou, J.P, Cao, L.J, Lin, M.Y, Zhang, R, Huang, Z.X. 登録日 2023-01-11 公開日 2024-04-24 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 beta-Xylosidase JB13GH39P28 (D41G) showing salt/ethanol/trypsin tolerance and transformation of notoginsenosides To Be Published
7O0O	Crystal structure of the B3 metallo-beta-lactamase L1 with hydrolysed ertapenem 分子名称: (2~{S},3~{R},4~{S})-2-[(2~{S},3~{R})-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3~{S},5~{S})-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl]sulfanyl-3-methyl-3,4-dihydro-2~{H}-pyrrole-5-carboxylic acid, Metallo-beta-lactamase L1, SULFATE ION, ... 著者 Hinchliffe, P, Spencer, J. 登録日 2021-03-26 公開日 2021-10-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystallography and QM/MM Simulations Identify Preferential Binding of Hydrolyzed Carbapenem and Penem Antibiotics to the L1 Metallo-beta-Lactamase in the Imine Form. J.Chem.Inf.Model., 61, 2021
3VEG	Rhodococcus jostii RHA1 DypB R244L variant in complex with heme 分子名称: CHLORIDE ION, DypB, PROTOPORPHYRIN IX CONTAINING FE 著者 Grigg, J.C, Singh, R, Armstrong, Z, Eltis, L.D, Murphy, M.E.P. 登録日 2012-01-07 公開日 2012-01-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Distal heme pocket residues of B-type dye-decolorizing peroxidase: arginine but not aspartate is essential for peroxidase activity. J.Biol.Chem., 287, 2012
3VED	Rhodococcus jostii RHA1 DypB D153H variant in complex with heme 分子名称: CHLORIDE ION, DypB, GLYCEROL, ... 著者 Grigg, J.C, Singh, R, Armstrong, Z, Eltis, L.D, Murphy, M.E.P. 登録日 2012-01-07 公開日 2012-01-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Distal heme pocket residues of B-type dye-decolorizing peroxidase: arginine but not aspartate is essential for peroxidase activity. J.Biol.Chem., 287, 2012
3VEE	Rhodococcus jostii RHA1 DypB N246A variant in complex with heme 分子名称: CHLORIDE ION, DypB, FORMIC ACID, ... 著者 Grigg, J.C, Singh, R, Armstrong, Z, Eltis, L.D, Murphy, M.E.P. 登録日 2012-01-07 公開日 2012-01-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Distal heme pocket residues of B-type dye-decolorizing peroxidase: arginine but not aspartate is essential for peroxidase activity. J.Biol.Chem., 287, 2012
8BSU	Crystal structure of the kainate receptor GluK3-H523A ligand binding domain in complex with kainate and the positive allosteric modulator BPAM344 at 2.9A resolution 分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, 4-cyclopropyl-7-fluoro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide, ACETATE ION, ... 著者 Venskutonyte, R, Frydenvang, K, Kastrup, J.S. 登録日 2022-11-26 公開日 2023-12-13 最終更新日 2024-07-03 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure. Febs J., 291, 2024
8BST	Crystal structure of the kainate receptor GluK3-H523A ligand binding domain in complex with kainate at 2.7A resolution 分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, ACETATE ION, CHLORIDE ION, ... 著者 Venskutonyte, R, Frydenvang, K, Kastrup, J.S. 登録日 2022-11-26 公開日 2023-12-13 最終更新日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure. Febs J., 291, 2024
8A4F	Human Interleukin-4 mutant - C3T-IL4 分子名称: Interleukin-4 著者 Vaz, D.C, Rodrigues, J.R, Mueller, T.D, Sebald, W, Redfield, C, Brito, R.M.M. 登録日 2022-06-11 公開日 2023-10-18 最終更新日 2024-01-17 実験手法 SOLUTION NMR 主引用文献 Lessons on protein structure from interleukin-4: All disulfides are not created equal. Proteins, 92, 2024
6FER	Crystal Structure of human DDR2 kinase in complex with 2-[4,5-difluoro-2-oxo-1'-(1H-pyrazolo[3,4-b]pyridine-5-carbonyl)spiro[indole-3,4'-piperidine]-1-yl]-N-(2,2,2-trifluoroethyl)acetamide 分子名称: 2-[4,5-bis(fluoranyl)-2-oxidanylidene-1'-(1~{H}-pyrazolo[3,4-b]pyridin-5-ylcarbonyl)spiro[indole-3,4'-piperidine]-1-yl]-~{N}-[2,2,2-tris(fluoranyl)ethyl]ethanamide, Discoidin domain-containing receptor 2 著者 Stihle, M, Richter, H, Benz, J, Kuhn, B, Rudolph, M.G. 登録日 2018-01-03 公開日 2018-11-28 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.87 Å) 主引用文献 DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome. Acs Chem.Biol., 14, 2019

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