PDB: 98225 件ウェブページステータス検索Chemie searchBIRD

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7OEP	C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 5-(1-(1,3-dimethoxypropan-2-yl)-5-morpholino-1H-benzo[d]imidazol-2-yl)-1,3-dimethylpyridin-2(1H)-one 分子名称: 1,2-ETHANEDIOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 5-[1-(1,3-dimethoxypropan-2-yl)-5-morpholin-4-yl-benzimidazol-2-yl]-1,3-dimethyl-pyridin-2-one, ... 著者 Chung, C. 登録日 2021-05-03 公開日 2021-07-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.801 Å) 主引用文献 Discovery of a Highly Selective BET BD2 Inhibitor from a DNA-Encoded Library Technology Screening Hit. J.Med.Chem., 64, 2021
7OER	C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH N-(2,2-diphenylethyl)-1,5-dimethyl-N-(2-(methylamino)-2-oxoethyl)-6-oxo-1,6-dihydropyridine-3-carboxamide 分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 2, N-(2,2-diphenylethyl)-1,5-dimethyl-N-[2-(methylamino)-2-oxidanylidene-ethyl]-6-oxidanylidene-pyridine-3-carboxamide 著者 Chung, C. 登録日 2021-05-03 公開日 2021-07-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.602 Å) 主引用文献 Discovery of a Highly Selective BET BD2 Inhibitor from a DNA-Encoded Library Technology Screening Hit. J.Med.Chem., 64, 2021
7OES	C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 1,5-dimethyl-N-(2-(methylamino)-2-oxoethyl)-6-oxo-N-(2-phenylpropyl)-1,6-dihydropyridine-3-carboxamide 分子名称: 1,2-ETHANEDIOL, 1,5-dimethyl-N-[2-(methylamino)-2-oxidanylidene-ethyl]-6-oxidanylidene-N-[(2S)-2-phenylpropyl]pyridine-3-carboxamide, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ... 著者 Chung, C. 登録日 2021-05-03 公開日 2021-07-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.602 Å) 主引用文献 Discovery of a Highly Selective BET BD2 Inhibitor from a DNA-Encoded Library Technology Screening Hit. J.Med.Chem., 64, 2021
6GGM	HLA-E*01:03 in complex with the Mtb44 peptide variant: Mtb44*P2-Phe. 分子名称: Beta-2-microglobulin, MHC class I antigen, Mtb44*P2-Phe peptide variant (ARG-PHE-PRO-ALA-LYS-ALA-PRO-LEU-LEU), ... 著者 Walters, L.C, Gillespie, G.M, McMichael, A.J, Rozbesky, D, Jones, E.Y, Harlos, K. 登録日 2018-05-03 公開日 2018-08-08 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.734 Å) 主引用文献 Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding. Nat Commun, 9, 2018
6GH4	HLA-E*01:03 in complex with the Mtb44 peptide variant: Mtb44*P2-Gln. 分子名称: ARG-GLN-PRO-ALA-LYS-ALA-PRO-LEU-LEU, Beta-2-microglobulin, MHC class I antigen, ... 著者 Walters, L.C, Gillespie, G.M, McMichael, A.J, Rozbesky, D, Jones, E.Y, Harlos, K. 登録日 2018-05-04 公開日 2018-08-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding. Nat Commun, 9, 2018
6GH1	HLA-E*01:03 in complex with Mtb44 分子名称: Beta-2-microglobulin, Enoyl-[acyl-carrier-protein] reductase [NADH], MHC class I antigen, ... 著者 Walters, L.C, Gillespie, G.M, McMichael, A.J, Rozbesky, D, Jones, E.Y, Harlos, K. 登録日 2018-05-04 公開日 2018-08-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding. Nat Commun, 9, 2018
6GHN	HLA-E*01:03 in complex with the Mtb44 peptide variant: Mtb44*P9-Phe. 分子名称: ARG-LEU-PRO-ALA-LYS-ALA-PRO-LEU-PHE, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... 著者 Walters, L.C, Gillespie, G.M, McMichael, A.J, Rozbesky, D, Jones, E.Y, Harlos, K. 登録日 2018-05-08 公開日 2018-08-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.542 Å) 主引用文献 Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding. Nat Commun, 9, 2018
6AAY	the Cas13b binary complex 分子名称: Bergeyella zoohelcum Cas13b (R1177A) mutant, RNA (52-MER) 著者 Bo, Z, Weiwei, Y, Yangmiao, Y, Ouyang, S.Y. 登録日 2018-07-19 公開日 2019-03-13 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Structural insights into Cas13b-guided CRISPR RNA maturation and recognition. Cell Res., 28, 2018
7OET	C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 1,5-dimethyl-N-(2-(methylamino)-2-oxo-1-(tetrahydro-2H-pyran-4-yl)ethyl)-6-oxo-N-(2-phenyl-2-(pyridin-2-yl)ethyl)-1,6-dihydropyridine-3-carboxamide 分子名称: 1,2-ETHANEDIOL, 1,5-dimethyl-~{N}-[(1~{R})-2-(methylamino)-1-(oxan-4-yl)-2-oxidanylidene-ethyl]-6-oxidanylidene-~{N}-[(2~{S})-2-phenyl-2-pyridin-2-yl-ethyl]pyridine-3-carboxamide, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ... 著者 Chung, C. 登録日 2021-09-21 公開日 2021-10-13 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 Discovery of a Highly Selective BET BD2 Inhibitor from a DNA-Encoded Library Technology Screening Hit. J.Med.Chem., 64, 2021
6GL1	HLA-E*01:03 in complex with the HIV epitope, RL9HIV 分子名称: ARG-MET-TYR-SER-PRO-THR-SER-ILE-LEU, Beta-2-microglobulin, MHC class I antigen, ... 著者 Walters, L.C, Gillespie, G.M, McMichael, A.J, Rozbesky, D, Jones, E.Y, Harlos, K. 登録日 2018-05-22 公開日 2018-08-08 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.623 Å) 主引用文献 Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding. Nat Commun, 9, 2018
6AOW	Crystal structure of lectin domain of F9 pilus adhesin FmlH from E. coli UTI89 分子名称: F9 pilus adhesin FmlH, SULFATE ION 著者 Kalas, V, Hultgren, S.J. 登録日 2017-08-16 公開日 2018-02-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection. Proc.Natl.Acad.Sci.USA, 115, 2018
6AOX	F9 pilus adhesin FmlH lectin domain from E. coli UTI89 co-crystallized with TF antigen 分子名称: Fml fimbrial adhesin FmlD, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose 著者 Kalas, V, Hultgren, S.J. 登録日 2017-08-16 公開日 2018-02-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection. Proc.Natl.Acad.Sci.USA, 115, 2018
6AS8	F9 pilus adhesin FmlH lectin domain from E. coli UTI89 co-crystallized with ortho-biphenyl-2'-carboxyl N-acetyl-beta-galactosaminoside 分子名称: Fml fimbrial adhesin FmlD, ortho-biphenyl-2'-carboxyl N-acetyl-beta-galactosaminoside 著者 Kalas, V, Hultgren, S.J. 登録日 2017-08-23 公開日 2018-02-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.101 Å) 主引用文献 Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection. Proc.Natl.Acad.Sci.USA, 115, 2018
6ARO	F9 pilus adhesin FmlH lectin domain from E. coli UTI89 co-crystallized with 8-hydroxyquinoline beta-galactoside 分子名称: 8-hydroxyquinoline beta-galactopyranoside, F9 pilus adhesin FmlH, SULFATE ION 著者 Kalas, V, Hultgren, S.J. 登録日 2017-08-23 公開日 2018-02-28 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection. Proc.Natl.Acad.Sci.USA, 115, 2018
6B9E	Human ATL1 mutant - R77A / F151S bound to GDP 分子名称: Atlastin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 O'Donnell, J.P, Sondermann, H. 登録日 2017-10-10 公開日 2017-12-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 A hereditary spastic paraplegia-associated atlastin variant exhibits defective allosteric coupling in the catalytic core. J. Biol. Chem., 293, 2018
8FEX	Inactivate state of Maribacter polysiphoniae Argonuate (short pAgo system) 分子名称: TIR-APAZ, short pAgo 著者 Shen, Z.F, Yang, X.Y, Fu, T.M. 登録日 2022-12-06 公開日 2023-08-23 最終更新日 2023-09-20 実験手法 ELECTRON MICROSCOPY (3.07 Å) 主引用文献 Oligomerization-mediated activation of a short prokaryotic Argonaute. Nature, 621, 2023
6ARM	F9 pilus adhesin FmlH lectin domain from E. coli UTI89 co-crystallized with o-nitrophenyl beta-galactoside (ONPG) 分子名称: 2-nitrophenyl beta-D-galactopyranoside, F9 pilus adhesin FmlH, SULFATE ION 著者 Kalas, V, Hultgren, S.J. 登録日 2017-08-22 公開日 2018-02-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection. Proc.Natl.Acad.Sci.USA, 115, 2018
6ARN	F9 pilus adhesin FmlH lectin domain from E. coli UTI89 co-crystallized with o-methoxyphenyl beta-galactoside (OMPG) 分子名称: 2-methoxyphenyl beta-D-galactopyranoside, Putative Fml fimbrial adhesin FmlD, SULFATE ION 著者 Kalas, V, Hultgren, S.J. 登録日 2017-08-22 公開日 2018-02-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection. Proc.Natl.Acad.Sci.USA, 115, 2018
5T49	Crystal structure of SeMet derivative BhGH81 分子名称: 1,2-ETHANEDIOL, BH0236 protein, PHOSPHATE ION 著者 Pluvinage, B, Boraston, A.B. 登録日 2016-08-29 公開日 2017-06-28 最終更新日 2020-01-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Analysis of a Family 81 Glycoside Hydrolase Implicates Its Recognition of beta-1,3-Glucan Quaternary Structure. Structure, 25, 2017
6AOY	F9 pilus adhesin FmlH lectin domain from E. coli UTI89 co-crystallized with o-nitrophenyl beta-galactoside (ONPG) 分子名称: 2-nitrophenyl beta-D-galactopyranoside, Fml fimbrial adhesin FmlD, SULFATE ION 著者 Kalas, V, Hultgren, S.J. 登録日 2017-08-16 公開日 2018-02-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection. Proc.Natl.Acad.Sci.USA, 115, 2018
1CIR	COMPLEX OF TWO FRAGMENTS OF CI2 [(1-40)(DOT)(41-64)] 分子名称: CHYMOTRYPSIN INHIBITOR 2 著者 Davis, B.J, Fersht, A.R. 登録日 1995-10-02 公開日 1996-01-29 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Towards the complete structural characterization of a protein folding pathway: the structures of the denatured, transition and native states for the association/folding of two complementary fragments of cleaved chymotrypsin inhibitor 2. Direct evidence for a nucleation-condensation mechanism Structure Fold.Des., 1, 1996
8FOJ	Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex in the post RNA handoff state 分子名称: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... 著者 Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. 登録日 2022-12-30 公開日 2023-05-31 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023
7WRQ	Structure of Human IGF1/IGFBP3/ALS Ternary Complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin-like growth factor-binding protein 3, Insulin-like growth factor-binding protein complex acid labile subunit, ... 著者 Kim, H, Fu, Y, Kim, H.M. 登録日 2022-01-27 公開日 2022-08-10 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural basis for assembly and disassembly of the IGF/IGFBP/ALS ternary complex Nat Commun, 13, 2022
6RJR	Crystal structure of a Fungal Catalase at 1.9 Angstrom 分子名称: CHLORIDE ION, Catalase, GLYCEROL, ... 著者 Gomez, S, Navas-Yuste, S, Payne, A.M, Rivera, W, Lopez-Estepa, M, Brangbour, C, Fulla, D, Juanhuix, J, Fernandez, F.J, Vega, M.C. 登録日 2019-04-29 公開日 2020-03-11 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.895 Å) 主引用文献 Peroxisomal catalases from the yeasts Pichia pastoris and Kluyveromyces lactis as models for oxidative damage in higher eukaryotes. Free Radic. Biol. Med., 141, 2019
8FOC	Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase in Apo state conformation I 分子名称: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... 著者 Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. 登録日 2022-12-30 公開日 2023-05-31 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023

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