8HX9
| Crystal structure of 4-amino-4-deoxychorismate synthase from Streptomyces venezuelae with chorismate | 分子名称: | (3R,4R)-3-[(1-carboxyethenyl)oxy]-4-hydroxycyclohexa-1,5-diene-1-carboxylic acid, 4-amino-4-deoxychorismate synthase, FORMIC ACID, ... | 著者 | Nakamichi, Y, Watanabe, M. | 登録日 | 2023-01-04 | 公開日 | 2023-10-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Structural basis for the allosteric pathway of 4-amino-4-deoxychorismate synthase. Acta Crystallogr D Struct Biol, 79, 2023
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8HX8
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8HX7
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8HX6
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8HX3
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8HWQ
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8HWH
| Cryo-EM Structure of D5 Apo-ssDNA form | 分子名称: | DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), Primase D5 | 著者 | Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H. | 登録日 | 2022-12-29 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus. Nat.Struct.Mol.Biol., 31, 2024
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8HWG
| D5 ATPrS-ADP-ssDNA form | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ... | 著者 | Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H. | 登録日 | 2022-12-29 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus. Nat.Struct.Mol.Biol., 31, 2024
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8HWF
| Cryo-EM Structure of D5 ADP-ssDNA form | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ... | 著者 | Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H. | 登録日 | 2022-12-29 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus. Nat.Struct.Mol.Biol., 31, 2024
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8HWE
| Cryo-EM Structure of D5 ATP-ADP form | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H. | 登録日 | 2022-12-29 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus. Nat.Struct.Mol.Biol., 31, 2024
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8HWD
| Cryo-EM Structure of D5 ADP form | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Primase D5 | 著者 | Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H. | 登録日 | 2022-12-29 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus. Nat.Struct.Mol.Biol., 31, 2024
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8HWC
| Cryo-EM Structure of D5 Apo | 分子名称: | Primase D5 | 著者 | Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H. | 登録日 | 2022-12-29 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus. Nat.Struct.Mol.Biol., 31, 2024
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8HWB
| D5 ATP-ADP-Apo-ssDNA IS2 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), ... | 著者 | Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H. | 登録日 | 2022-12-29 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus. Nat.Struct.Mol.Biol., 31, 2024
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8HWA
| D5 ATP-ADP-Apo-ssDNA IS1 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), ... | 著者 | Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H. | 登録日 | 2022-12-29 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus. Nat.Struct.Mol.Biol., 31, 2024
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8HW6
| Crystal structure of Heterodera glycines chitinase 2 | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | 著者 | Chen, W, Chen, Q, Wang, D, Yang, Q. | 登録日 | 2022-12-29 | 公開日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.923 Å) | 主引用文献 | Crystal structure of Heterodera glycines chitinase 2 To Be Published
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8HW3
| Limosilactobacillus reuteri N1 GtfB-acarbose | 分子名称: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, GLYCEROL, SODIUM ION, ... | 著者 | Dong, J.J, Bai, Y.X. | 登録日 | 2022-12-28 | 公開日 | 2024-01-03 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | Insights into the Structure-Function Relationship of GH70 GtfB alpha-Glucanotransferases from the Crystal Structure and Molecular Dynamic Simulation of a Newly Characterized Limosilactobacillus reuteri N1 GtfB Enzyme. J.Agric.Food Chem., 72, 2024
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8HW1
| Far-red light-harvesting complex of Antarctic alga Prasiola crispa | 分子名称: | (1S)-4-[(1E,3Z,5E,7E,9E,11E,13E,15E,17E)-3-(hydroxymethyl)-7,12,16-trimethyl-18-[(1R,4S)-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethyl-cyclohex-3-en-1-ol, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, CHLOROPHYLL A, ... | 著者 | Kosugi, M, Kawasaki, M, Shibata, Y, Moriya, T, Adachi, N, Senda, T. | 登録日 | 2022-12-28 | 公開日 | 2023-01-18 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | 主引用文献 | Uphill energy transfer mechanism for photosynthesis in an Antarctic alga. Nat Commun, 14, 2023
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8HW0
| the structure of AKR6D1 | 分子名称: | GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADPH-dependent aldo/keto reductase AKR6D1 | 著者 | Chen, M, Yang, H. | 登録日 | 2022-12-28 | 公開日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | structure of AKR6D1 To Be Published
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8HVP
| STRUCTURE AT 2.5-ANGSTROMS RESOLUTION OF CHEMICALLY SYNTHESIZED HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 PROTEASE COMPLEXED WITH A HYDROXYETHYLENE*-BASED INHIBITOR | 分子名称: | HIV-1 PROTEASE, INHIBITOR VAL-SER-GLN-ASN-LEU-PSI(CH(OH)-CH2)-VAL-ILE-VAL (U-85548E) | 著者 | Jaskolski, M, Miller, M, Tomasselli, A.G, Sawyer, T.K, Staples, D.G, Heinrikson, R.L, Schneider, J, Kent, S.B.H, Wlodawer, A. | 登録日 | 1990-10-26 | 公開日 | 1993-10-31 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure at 2.5-A resolution of chemically synthesized human immunodeficiency virus type 1 protease complexed with a hydroxyethylene-based inhibitor. Biochemistry, 30, 1991
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8HVO
| Crystal structure of SARS-Cov-2 main protease V186F mutant in complex with PF07321332 | 分子名称: | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5 | 著者 | Zou, X.F, Zhang, J, Li, J. | 登録日 | 2022-12-27 | 公開日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal structure of SARS-Cov-2 main protease
V186F mutant in complex with PF07321332 To Be Published
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8HVN
| Crystal structure of SARS-Cov-2 main protease P132H mutant in complex with PF07321332 | 分子名称: | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5 | 著者 | Li, W.W, Zhang, J, Li, J. | 登録日 | 2022-12-27 | 公開日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of SARS-Cov-2 main protease
P132H mutant in complex with PF07321332 To Be Published
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8HVM
| Crystal structure of SARS-Cov-2 main protease K90R mutant in complex with PF07321332 | 分子名称: | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5 | 著者 | Wang, J, Zhang, J, Li, J. | 登録日 | 2022-12-27 | 公開日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Crystal structure of SARS-Cov-2 main protease
K90R mutant in complex with PF07321332 To Be Published
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8HVL
| Crystal structure of SARS-Cov-2 main protease M49I mutant in complex with PF07321332 | 分子名称: | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5 | 著者 | Zou, X.F, Zhang, J, Li, J. | 登録日 | 2022-12-27 | 公開日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Crystal structure of SARS-Cov-2 main protease
M49I mutant in complex with PF07321332 To Be Published
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8HVK
| Crystal structure of SARS-Cov-2 main protease G15S mutant in complex with PF07321332 | 分子名称: | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5 | 著者 | Zeng, P, Zhang, J, Li, J. | 登録日 | 2022-12-27 | 公開日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Crystal structure of SARS-Cov-2 main protease
G15S mutant in complex with PF07321332 To Be Published
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8HVI
| Activation mechanism of GPR132 by compound NOX-6-7 | 分子名称: | 3-methyl-5-[(4-oxidanylidene-4-phenyl-butanoyl)amino]-1-benzofuran-2-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Wang, J.L, Ding, J.H, Sun, J.P, Yu, X. | 登録日 | 2022-12-26 | 公開日 | 2023-10-11 | 最終更新日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | 主引用文献 | Functional screening and rational design of compounds targeting GPR132 to treat diabetes. Nat Metab, 5, 2023
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