7O88
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4BIM
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7JRX
| Crystal structure of the R64F mutant of Bauhinia Bauhinioides complexed with Bovine Chymotrypsin | 分子名称: | Chymotrypsin A chain A, Chymotrypsin A chain B, Chymotrypsin A chain C, ... | 著者 | Li, M, Wlodawer, A, Gustchina, A. | 登録日 | 2020-08-13 | 公開日 | 2021-07-21 | 最終更新日 | 2021-08-11 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI. Acta Crystallogr D Struct Biol, 77, 2021
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5OM7
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6HGH
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6HGD
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6V2Q
| HLA-B*57:03 presenting the peptide LSSPVTKSF | 分子名称: | ACETATE ION, Beta-2-microglobulin, HLA-B alpha chain (B*5703GB), ... | 著者 | Maclachlan, B, Rossjohn, J, Vivian, J.P. | 登録日 | 2019-11-25 | 公開日 | 2020-05-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function. Proc.Natl.Acad.Sci.USA, 117, 2020
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6V3J
| KIR3DL1 in complex with HLA-B*57:03 presenting the peptide LSSPVTKSF | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, HLA-B alpha chain (B*5703GB), ... | 著者 | Maclachlan, B, Rossjohn, J, Vivian, J.P. | 登録日 | 2019-11-25 | 公開日 | 2020-05-20 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function. Proc.Natl.Acad.Sci.USA, 117, 2020
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6HGL
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6V2O
| HLA-B*57:01 presenting the peptide ASLNLPAVSW | 分子名称: | ACETATE ION, Beta-2-microglobulin, MHC class I antigen, ... | 著者 | Maclachlan, B, Rossjohn, J, Vivian, J.P. | 登録日 | 2019-11-25 | 公開日 | 2020-05-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | 主引用文献 | The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function. Proc.Natl.Acad.Sci.USA, 117, 2020
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6HGI
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6V2P
| HLA-B*57:03 presenting the peptide ASLNLPAVSW | 分子名称: | ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | 著者 | Maclachlan, B, Rossjohn, J, Vivian, J.P. | 登録日 | 2019-11-25 | 公開日 | 2020-05-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function. Proc.Natl.Acad.Sci.USA, 117, 2020
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6HGE
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8TXY
| X-ray crystal structure of JRD-SIK1/2i-3 bound to a MARK2-SIK2 chimera | 分子名称: | DI(HYDROXYETHYL)ETHER, N-[(5P,8R)-5-(2-cyano-5-{[(3R)-1-methylpyrrolidin-3-yl]methoxy}pyridin-4-yl)pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide, SULFATE ION, ... | 著者 | Raymond, D.D, Lemke, C.T, Shaffer, P.L, Collins, B, Steele, R, Seierstad, M. | 登録日 | 2023-08-24 | 公開日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Identification of highly selective SIK1/2 inhibitors that modulate innate immune activation and suppress intestinal inflammation. Proc.Natl.Acad.Sci.USA, 121, 2024
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5NES
| Discovery, crystal structures and atomic force microscopy study of thioether ligated D,L-cyclic antimicrobial peptides against multidrug resistant Pseudomonas aeruginosa | 分子名称: | 1,3-dimethylbenzene, 3,7-anhydro-2,8-dideoxy-L-glycero-D-gluco-octonic acid, CALCIUM ION, ... | 著者 | Reymond, J.-L, Darbre, T, Stocker, A, Hong, W, van Delden, C, Koehler, T, Luscher, A, Visini, R, Fu, Y, Di Bonaventura, I, He, R. | 登録日 | 2017-03-11 | 公開日 | 2017-09-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.606 Å) | 主引用文献 | Design, crystal structure and atomic force microscopy study of thioether ligated d,l-cyclic antimicrobial peptides against multidrug resistant Pseudomonas aeruginosa. Chem Sci, 8, 2017
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5NF0
| Discovery, crystal structures and atomic force microscopy study of thioether ligated D,L-cyclic antimicrobial peptides against multidrug resistant Pseudomonas aeruginosa | 分子名称: | 3,7-anhydro-2,8-dideoxy-L-glycero-D-gluco-octonic acid, CALCIUM ION, CYD-TRP-TRD-LYS-LYD-LYS-LYD-LYS-TRD-TRP-CYD-GLY, ... | 著者 | Reymond, J.-L, Darbre, T, Stocker, A, Hong, W, van Delden, C, Koehler, T, Luscher, A, Visini, R, Fu, Y, Di Bonaventura, I, He, R. | 登録日 | 2017-03-13 | 公開日 | 2017-09-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.271 Å) | 主引用文献 | Design, crystal structure and atomic force microscopy study of thioether ligated d,l-cyclic antimicrobial peptides against multidrug resistant Pseudomonas aeruginosa. Chem Sci, 8, 2017
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1M21
| Crystal structure analysis of the peptide amidase PAM in complex with the competitive inhibitor chymostatin | 分子名称: | CHYMOSTATIN, Peptide Amidase | 著者 | Labahn, J, Neumann, S, Buldt, G, Kula, M.-R, Granzin, J. | 登録日 | 2002-06-21 | 公開日 | 2002-10-16 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | An alternative mechanism for amidase signature enzymes J.MOL.BIOL., 322, 2002
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5NEY
| Discovery, crystal structures and atomic force microscopy study of thioether ligated D,L-cyclic antimicrobial peptides against multidrug resistant Pseudomonas aeruginosa | 分子名称: | 3,7-anhydro-2,8-dideoxy-L-glycero-D-gluco-octonic acid, CALCIUM ION, CYS-TRD-TRP-LYD-LYS-LYD-LYS-LYD-TRP-TRD-CYS-ALA, ... | 著者 | Reymond, J.-L, Darbre, T, Stocker, A, Hong, W, van Delden, C, Koehler, T, Luscher, A, Visini, R, Fu, Y, Di Bonaventura, I, He, R. | 登録日 | 2017-03-13 | 公開日 | 2017-09-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Design, crystal structure and atomic force microscopy study of thioether ligated d,l-cyclic antimicrobial peptides against multidrug resistant Pseudomonas aeruginosa. Chem Sci, 8, 2017
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6Q40
| A secreted LysM effector of the wheat pathogen Zymoseptoria tritici protects the fungal hyphae against chitinase hydrolysis through ligand-dependent polymerisation of LysM homodimers | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, LysM domain-containing protein | 著者 | Mesters, J.R, Saleem-Batcha, R, Sanchez-Vallet, A, Thomma, B.P.H.J. | 登録日 | 2018-12-05 | 公開日 | 2019-10-16 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.412 Å) | 主引用文献 | A secreted LysM effector protects fungal hyphae through chitin-dependent homodimer polymerization. Plos Pathog., 16, 2020
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1P0E
| CRYSTAL STRUCTURE OF ZYMOMONAS MOBILIS tRNA-GUANINE TRANSGLYCOSYLASE (TGT) COCRYSTALLISED WITH PREQ1 AT PH 5.5 | 分子名称: | 7-DEAZA-7-AMINOMETHYL-GUANINE, Queuine tRNA-ribosyltransferase, ZINC ION | 著者 | Brenk, R, Stubbs, M.T, Heine, A, Reuter, K, Klebe, G. | 登録日 | 2003-04-10 | 公開日 | 2003-09-30 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Flexible adaptations in the structure of the tRNA-modifying enzyme tRNA-guanine transglycosylase
and their implications for substrate selectivity, reaction mechanism and structure-based drug design Chembiochem, 4, 2003
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1PUD
| TRNA-GUANINE TRANSGLYCOSYLASE | 分子名称: | TRNA-GUANINE TRANSGLYCOSYLASE, ZINC ION | 著者 | Romier, C, Reuter, K, Suck, D, Ficner, R. | 登録日 | 1996-06-28 | 公開日 | 1997-07-07 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structure of tRNA-guanine transglycosylase: RNA modification by base exchange. EMBO J., 15, 1996
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5UG0
| Human antibody H2897 in complex with influenza hemagglutinin H1 Solomon Islands/03/2006 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2897 heavy chain, ... | 著者 | Raymond, D.D, Caradonna, T, Schmidt, A.G, Harrison, S.C. | 登録日 | 2017-01-06 | 公開日 | 2017-05-31 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | CryoEM Structure of an Influenza Virus Receptor-Binding Site Antibody-Antigen Interface. J. Mol. Biol., 429, 2017
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1P0D
| CRYSTAL STRUCTURE OF ZYMOMONAS MOBILIS tRNA-GUANINE TRANSGLYCOSYLASE (TGT) CRYSTALLISED AT PH 5.5 | 分子名称: | Queuine tRNA-ribosyltransferase, ZINC ION | 著者 | Brenk, R, Stubbs, M.T, Heine, A, Reuter, K, Klebe, G. | 登録日 | 2003-04-10 | 公開日 | 2003-09-30 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Flexible adaptations in the structure of the tRNA-modifying enzyme
tRNA-guanine transglycosylase and their implications for substrate selectivity,
reaction mechanism and structure-based drug design Chembiochem, 4, 2003
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5W1K
| JUNV GP1 CR1-10 Fab CR1-28 Fab complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR1-10 Fab heavy chain, ... | 著者 | Raymond, D.D, Clark, L.E, Abraham, J. | 登録日 | 2017-06-03 | 公開日 | 2018-05-30 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.99 Å) | 主引用文献 | Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses. Nat Commun, 9, 2018
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5W1M
| MACV GP1 CR1-07 Fab complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR1-07 Fab heavy chain, ... | 著者 | Raymond, D.D, Clark, L.E, Abraham, J. | 登録日 | 2017-06-03 | 公開日 | 2018-05-30 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.91 Å) | 主引用文献 | Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses. Nat Commun, 9, 2018
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