7BDJ
 
 | | Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and mant-ATPgammaS | | 分子名称: | MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8, U5 small nuclear ribonucleoprotein 200 kDa helicase, ... | | 著者 | Vester, K, Santos, K.F, Absmeier, E, Wahl, M.C. | | 登録日 | 2020-12-21 | | 公開日 | 2021-06-09 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2.
J.Biol.Chem., 297, 2021
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7BDI
 | | Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and ATPgammaS | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Pre-mRNA-processing-splicing factor 8, ... | | 著者 | Vester, K, Santos, K.F, Absmeier, E, Wahl, M.C. | | 登録日 | 2020-12-21 | | 公開日 | 2021-06-09 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2.
J.Biol.Chem., 297, 2021
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7DTK
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7DVQ
 | | Cryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex) | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, 5'-O-[(S)-hydroxy{[(R)-hydroxy{[(S)-hydroxy(methoxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]guanosine, Armadillo repeat-containing protein 7, ... | | 著者 | Bai, R, Wan, R, Wang, L, Xu, K, Zhang, Q, Lei, J, Shi, Y. | | 登録日 | 2021-01-14 | | 公開日 | 2021-03-31 | | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | | 主引用文献 | Structure of the activated human minor spliceosome.
Science, 371, 2021
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7LIU
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7LUV
 | | Cryo-EM structure of the yeast THO-Sub2 complex | | 分子名称: | ATP-dependent RNA helicase SUB2, THO complex subunit 2, THO complex subunit HPR1, ... | | 著者 | Xie, Y, Ren, Y. | | 登録日 | 2021-02-23 | | 公開日 | 2021-04-14 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Cryo-EM structure of the yeast TREX complex and coordination with the SR-like protein Gbp2.
Elife, 10, 2021
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7MQJ
 | | Dhr1 Helicase Core | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Probable ATP-dependent RNA helicase DHR1 | | 著者 | Miller, L, Chaker-Margot, M, Klinge, S. | | 登録日 | 2021-05-05 | | 公開日 | 2021-09-22 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Nucleolar maturation of the human small subunit processome.
Science, 373, 2021
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7MQA
 | | Cryo-EM structure of the human SSU processome, state post-A1 | | 分子名称: | 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | | 著者 | Vanden Broeck, A, Singh, S, Klinge, S. | | 登録日 | 2021-05-05 | | 公開日 | 2021-09-22 | | 最終更新日 | 2021-09-29 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Nucleolar maturation of the human small subunit processome.
Science, 373, 2021
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7OI6
 | | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 1 | | 分子名称: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Cheng, J, Berninghausen, O, Beckmann, R. | | 登録日 | 2021-05-11 | | 公開日 | 2021-10-13 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (5.7 Å) | | 主引用文献 | A distinct assembly pathway of the human 39S late pre-mitoribosome.
Nat Commun, 12, 2021
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7OHX
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7OHS
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7OHW
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7OHP
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7OHR
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7OHV
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7EVN
 | | The cryo-EM structure of the DDX42-SF3b complex | | 分子名称: | ATP-dependent RNA helicase DDX42, PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, ... | | 著者 | Zhang, X, Zhan, X, Shi, Y. | | 登録日 | 2021-05-21 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-01-17 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural insights into branch site proofreading by human spliceosome
Nat.Struct.Mol.Biol., 2024
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7EVO
 | | The cryo-EM structure of the human 17S U2 snRNP | | 分子名称: | HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, RNA helicase, ... | | 著者 | Zhang, X, Zhan, X, Shi, Y. | | 登録日 | 2021-05-21 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Structural insights into branch site proofreading by human spliceosome.
Nat.Struct.Mol.Biol., 2024
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7OQE
 | | Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1) | | 分子名称: | 56 kDa U1 small nuclear ribonucleoprotein component, ACT1 pre-mRNA (delta BS-A), Cold sensitive U2 snRNA suppressor 1, ... | | 著者 | Zhang, Z, Rigo, N, Dybkov, O, Fourmann, J, Will, C.L, Kumar, V, Urlaub, H, Stark, H, Luehrmann, R. | | 登録日 | 2021-06-03 | | 公開日 | 2021-08-11 | | 最終更新日 | 2021-09-29 | | 実験手法 | ELECTRON MICROSCOPY (5.9 Å) | | 主引用文献 | Structural insights into how Prp5 proofreads the pre-mRNA branch site.
Nature, 596, 2021
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7OQB
 | | The U2 part of Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1) | | 分子名称: | ACT1 pre-mRNA (delta-BS-A), Cold sensitive U2 snRNA suppressor 1, Pre-mRNA-processing ATP-dependent RNA helicase PRP5, ... | | 著者 | Zhang, Z, Rigo, N, Dybkov, O, Fourmann, J, Will, C.L, Kumar, V, Urlaub, H, Stark, H, Luehrmann, R. | | 登録日 | 2021-06-03 | | 公開日 | 2021-08-11 | | 最終更新日 | 2021-09-22 | | 実験手法 | ELECTRON MICROSCOPY (9 Å) | | 主引用文献 | Structural insights into how Prp5 proofreads the pre-mRNA branch site.
Nature, 596, 2021
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7OS1
 | | Cryo-EM structure of Brr2 in complex with Fbp21 | | 分子名称: | U5 small nuclear ribonucleoprotein 200 kDa helicase, WW domain-binding protein 4 | | 著者 | Bergfort, A, Hilal, T, Weber, G, Wahl, M.C. | | 登録日 | 2021-06-07 | | 公開日 | 2022-02-23 | | 最終更新日 | 2022-03-30 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling.
Nucleic Acids Res., 50, 2022
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7OS2
 | | Cryo-EM structure of Brr2 in complex with Jab1/MPN and C9ORF78 | | 分子名称: | Pre-mRNA-processing-splicing factor 8, Telomere length and silencing protein 1 homolog, U5 small nuclear ribonucleoprotein 200 kDa helicase | | 著者 | Bergfort, A, Hilal, T, Weber, G, Wahl, M.C. | | 登録日 | 2021-06-07 | | 公開日 | 2022-02-23 | | 最終更新日 | 2022-03-30 | | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | | 主引用文献 | The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling.
Nucleic Acids Res., 50, 2022
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7NAC
 | | State E2 nucleolar 60S ribosomal biogenesis intermediate - Composite model | | 分子名称: | 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... | | 著者 | Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. | | 登録日 | 2021-06-21 | | 公開日 | 2022-11-09 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
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7NAD
 | | State E2 nucleolar 60S ribosomal biogenesis intermediate - Spb4 local refinement model | | 分子名称: | 25S rRNA, 5.8S rRNA, 60S ribosomal protein L17-A, ... | | 著者 | Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. | | 登録日 | 2021-06-21 | | 公開日 | 2022-11-09 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
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7R6Q
 | | State E2 nucleolar 60S ribosome biogenesis intermediate - Foot region model | | 分子名称: | 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... | | 著者 | Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. | | 登録日 | 2021-06-23 | | 公開日 | 2022-11-09 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | | 主引用文献 | Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
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7R72
 | | State E1 nucleolar 60S ribosome biogenesis intermediate - Spb4 local model | | 分子名称: | 25S rRNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, 5.8S rRNA, ... | | 著者 | Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. | | 登録日 | 2021-06-24 | | 公開日 | 2022-11-09 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | | 主引用文献 | Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
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