PDB: 909 件ウェブページステータス検索Chemie searchBIRD

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6G90	Prespliceosome structure provides insight into spliceosome assembly and regulation (map A2) 分子名称: 56 kDa U1 small nuclear ribonucleoprotein component, Cold sensitive U2 snRNA suppressor 1, Pre-mRNA-processing factor 39, ... 著者 Plaschka, C, Lin, P.-C, Charenton, C, Nagai, K. 登録日 2018-04-10 公開日 2018-08-22 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Prespliceosome structure provides insights into spliceosome assembly and regulation. Nature, 559, 2018
5YZG	The Cryo-EM Structure of Human Catalytic Step I Spliceosome (C complex) at 4.1 angstrom resolution 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Zhan, X, Yan, C, Zhang, X, Lei, J, Shi, Y. 登録日 2017-12-14 公開日 2018-08-08 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structure of a human catalytic step I spliceosome Science, 359, 2018
5Y88	Cryo-EM structure of the intron-lariat spliceosome ready for disassembly from S.cerevisiae at 3.5 angstrom 分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Intron lariat, ... 著者 Wan, R, Yan, C, Bai, R, Lei, J, Shi, Y. 登録日 2017-08-20 公開日 2018-08-01 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.46 Å) 主引用文献 Structure of an Intron Lariat Spliceosome from Saccharomyces cerevisiae Cell(Cambridge,Mass.), 171, 2017
5YLZ	Cryo-EM Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae at 3.6 angstrom 分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... 著者 Wan, R, Yan, C, Bai, R, Lei, J, Shi, Y. 登録日 2017-10-20 公開日 2018-07-18 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae Cell, 171, 2017
6DCL	Crystal structure of UP1 bound to pri-miRNA-18a terminal loop 分子名称: 1,2-ETHANEDIOL, Heterogeneous nuclear ribonucleoprotein A1, RNA (5'-R(*AP*GP*UP*AP*GP*AP*UP*UP*AP*GP*C)-3') 著者 Kooshapur, H, Sattler, M. 登録日 2018-05-07 公開日 2018-06-27 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.497 Å) 主引用文献 Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1. Nat Commun, 9, 2018
6F4H	Crystal structure of the Drosophila melanogaster SNF/U1-SL2 complex 分子名称: CITRATE ANION, U1 small nuclear ribonucleoprotein A, U1-SL2 著者 Weber, G, Holton, N, Hall, K.B, DeKoster, G, Wahl, M.C. 登録日 2017-11-29 公開日 2018-06-20 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Molecular principles underlying dual RNA specificity in the Drosophila SNF protein. Nat Commun, 9, 2018
6F4G	'Crystal structure of the Drosophila melanogaster SNF/U2A'/U2-SL4 complex 分子名称: CHLORIDE ION, Probable U2 small nuclear ribonucleoprotein A', SULFATE ION, ... 著者 Weber, G, DeKoster, G, Holton, N, Hall, K.B, Wahl, M.C. 登録日 2017-11-29 公開日 2018-06-20 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular principles underlying dual RNA specificity in the Drosophila SNF protein. Nat Commun, 9, 2018
6F4J	Crystal structure of Drosophila melanogaster SNF/U2A' complex 分子名称: POLYETHYLENE GLYCOL (N=34), Probable U2 small nuclear ribonucleoprotein A', SULFATE ION, ... 著者 Weber, G, DeKoster, G, Holton, N, Hall, K.B, Wahl, M.C. 登録日 2017-11-29 公開日 2018-06-20 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Molecular principles underlying dual RNA specificity in the Drosophila SNF protein. Nat Commun, 9, 2018
6F4I	Crystal structure of Drosophila melanogaster SNF 分子名称: U1 small nuclear ribonucleoprotein A 著者 Weber, G, Holton, N, Hall, K.B, DeKoster, G, Wahl, M.C. 登録日 2017-11-29 公開日 2018-06-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Molecular principles underlying dual RNA specificity in the Drosophila SNF protein. Nat Commun, 9, 2018
6CMN	Co-Crystal Structure of HIV-1 TAR Bound to Lab-Evolved RRM TBP6.7 分子名称: TAR-Binding Protein 6.7, Trans-Activation Response RNA Element 著者 Belashov, I.A, Wedekind, J.E. 登録日 2018-03-05 公開日 2018-06-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.796 Å) 主引用文献 Structure of HIV TAR in complex with a Lab-Evolved RRM provides insight into duplex RNA recognition and synthesis of a constrained peptide that impairs transcription. Nucleic Acids Res., 46, 2018
6D6V	CryoEM structure of Tetrahymena telomerase with telomeric DNA at 4.8 Angstrom resolution 分子名称: DNA (5'-D(P*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*G)-3'), RNA (159-MER), Telomerase associated protein p65, ... 著者 Jiang, J, Wang, Y, Susac, L, Chan, H, Basu, R, Zhou, Z.H, Feigon, J. 登録日 2018-04-22 公開日 2018-05-30 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Structure of Telomerase with Telomeric DNA. Cell, 173, 2018
5YVG	Crystal structure of Karyopherin beta2 in complex with FUS(full length) 分子名称: RNA-binding protein FUS, Transportin-1 著者 Yoshizawa, T, Fung, H.Y.J, Chook, Y.M. 登録日 2017-11-25 公開日 2018-05-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (4.05 Å) 主引用文献 Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites. Cell, 173, 2018
6ASO	Structure of yeast U6 snRNP with 3'-phosphate terminated U6 RNA 分子名称: MAGNESIUM ION, MANGANESE (II) ION, POTASSIUM ION, ... 著者 Montemayor, E.J, Brow, D.A, Butcher, S.E. 登録日 2017-08-25 公開日 2018-05-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Architecture of the U6 snRNP reveals specific recognition of 3'-end processed U6 snRNA. Nat Commun, 9, 2018
5VSU	Structure of yeast U6 snRNP with 2'-phosphate terminated U6 RNA 分子名称: Saccharomyces cerevisiae strain T8 chromosome XII sequence, U4/U6 snRNA-associated-splicing factor PRP24, U6 snRNA-associated Sm-like protein LSm2, ... 著者 Montemayor, E.J. 登録日 2017-05-12 公開日 2018-05-09 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Architecture of the U6 snRNP reveals specific recognition of 3'-end processed U6 snRNA. Nat Commun, 9, 2018
6D0Y	X-ray Crystal Structure of PGC-1beta C-terminus bound to the CBP80-CBP20 Cap Binding Complex 分子名称: MAGNESIUM ION, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ... 著者 Gleghorn, M.L, Maquat, L.E. 登録日 2018-04-11 公開日 2018-04-25 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (2.676 Å) 主引用文献 Transcriptional coactivator PGC-1 alpha contains a novel CBP80-binding motif that orchestrates efficient target gene expression. Genes Dev., 32, 2018
5Z3G	Cryo-EM structure of a nucleolar pre-60S ribosome (Rpf1-TAP) 分子名称: 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... 著者 Zhu, X, Zhou, D, Ye, K. 登録日 2018-01-06 公開日 2018-04-11 最終更新日 2019-11-06 実験手法 ELECTRON MICROSCOPY (3.65 Å) 主引用文献 Cryo-EM structure of an early precursor of large ribosomal subunit reveals a half-assembled intermediate. Protein Cell, 10, 2019
5W0G	Structure of U2AF65 (U2AF2) RRM1 at 1.07 resolution 分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ACETATE ION, Splicing factor U2AF 65 kDa subunit, ... 著者 Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. 登録日 2017-05-30 公開日 2018-04-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.07 Å) 主引用文献 Cancer-Associated Mutations Mapped on High-Resolution Structures of the U2AF2 RNA Recognition Motifs. Biochemistry, 56, 2017
5W0H	Structure of U2AF65 (U2AF2) RRM2 at 1.11 Angstrom Resolution 分子名称: Splicing factor U2AF 65 kDa subunit 著者 Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. 登録日 2017-05-30 公開日 2018-04-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.11 Å) 主引用文献 Cancer-Associated Mutations Mapped on High-Resolution Structures of the U2AF2 RNA Recognition Motifs. Biochemistry, 56, 2017
5WPA	Structure of human SFPQ/PSPC1 heterodimer 分子名称: Paraspeckle component 1, Splicing factor, proline- and glutamine-rich 著者 Lee, M. 登録日 2017-08-04 公開日 2018-03-21 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Crystal structure of a SFPQ/PSPC1 heterodimer provides insights into preferential heterodimerization of human DBHS family proteins. J. Biol. Chem., 293, 2018
6FEC	Human cap-dependent 48S pre-initiation complex 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Schaffitzel, C, Schaffitzel, C. 登録日 2017-12-31 公開日 2018-03-14 最終更新日 2018-10-03 実験手法 ELECTRON MICROSCOPY (6.3 Å) 主引用文献 Structure of a human cap-dependent 48S translation pre-initiation complex. Nucleic Acids Res., 46, 2018
6C0F	Yeast nucleolar pre-60S ribosomal subunit (state 2) 分子名称: 5.8S rRNA, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ... 著者 Sanghai, Z.A, Miller, L, Barandun, J, Hunziker, M, Chaker-Margot, M, Klinge, S. 登録日 2017-12-29 公開日 2018-03-14 最終更新日 2020-01-08 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Modular assembly of the nucleolar pre-60S ribosomal subunit. Nature, 556, 2018
6CB1	Yeast nucleolar pre-60S ribosomal subunit (state 3) 分子名称: 35S pre-ribosomal RNA miscRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... 著者 Sanghai, Z.A, Miller, L, Barandun, J, Hunziker, M, Chaker-Margot, M, Klinge, S. 登録日 2018-02-01 公開日 2018-03-14 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Modular assembly of the nucleolar pre-60S ribosomal subunit. Nature, 556, 2018
6ES4	A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets 分子名称: 1,2-ETHANEDIOL, SULFATE ION, Syncrip, ... 著者 Hobor, F, Dallmann, A, Ball, N.J, Cicchini, C, Battistelli, C, Ogrodowicz, R.W, Christodoulou, E, Martin, S.R, Castello, A, Tripodi, M, Taylor, I.A, Ramos, A. 登録日 2017-10-19 公開日 2018-03-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets. Nat Commun, 9, 2018
6BK8	S. cerevisiae spliceosomal post-catalytic P complex 分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Lea1, ... 著者 Liu, S, Li, X, Zhou, Z.H, Zhao, R. 登録日 2017-11-07 公開日 2018-02-21 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structure of the yeast spliceosomal postcatalytic P complex. Science, 358, 2017
5OBN	NMR solution structure of U11/U12 65K protein's C-terminal RRM domain (381-516) 分子名称: RNA-binding protein 40 著者 Norppa, A.J, Kauppala, T.M, Heikkinen, H.A, Verma, B, Iwai, H, Frilander, M.J. 登録日 2017-06-28 公開日 2018-01-24 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Mutations in the U11/U12-65K protein associated with isolated growth hormone deficiency lead to structural destabilization and impaired binding of U12 snRNA. RNA, 24, 2018

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