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1K2M
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BU of 1k2m by Molmil
Solution Structure of the FHA2 Domain of Rad53 Complexed with a Phosphotyrosyl Peptide Derived from Rad9
分子名称: DNA repair protein Rad9, Protein Kinase SPK1
著者Byeon, I.-J.L, Yongkiettrakul, S, Tsai, M.-D.
登録日2001-09-28
公開日2001-12-05
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Solution structure of the yeast Rad53 FHA2 complexed with a phosphothreonine peptide pTXXL: comparison with the structures of FHA2-pYXL and FHA1-pTXXD complexes.
J.Mol.Biol., 314, 2001
8JZM
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BU of 8jzm by Molmil
The inhibitor of Toll-like receptor signaling o-vanillin binds covalently to MAL/TIRAP Lys-210
分子名称: Toll/interleukin-1 receptor domain-containing adapter protein
著者Rahaman, M.H, Jia, X, Maxwell, M.J, Mobli, M, Kobe, B.
登録日2023-07-05
公開日2024-05-01
実験手法SOLUTION NMR
主引用文献o-Vanillin binds covalently to MAL/TIRAP Lys-210 but independently inhibits TLR2.
J Enzyme Inhib Med Chem, 39, 2024
8K3C
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BU of 8k3c by Molmil
Nipah virus Attachment glycoprotein with 41-6 antibody fragment
分子名称: Glycoprotein G, Heavy chain of 41-6 Fab fragments, Light chain of 41-6 Fab fragment
著者Sun, M.M.
登録日2023-07-15
公開日2024-05-01
実験手法ELECTRON MICROSCOPY (2.88 Å)
主引用文献Potent human neutralizing antibodies against Nipah virus derived from two ancestral antibody heavy chains.
Nat Commun, 15, 2024
4DQC
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BU of 4dqc by Molmil
Crystal Structure of (G16C/L38C) HIV-1 Protease in Complex with DRV
分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, Aspartyl protease, GLYCEROL, ...
著者Schiffer, C.A, Mittal, S.
登録日2012-02-15
公開日2012-03-07
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Hydrophobic core flexibility modulates enzyme activity in HIV-1 protease.
J.Am.Chem.Soc., 134, 2012
4DIK
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BU of 4dik by Molmil
Flavo Di-iron protein H90A mutant from Thermotoga maritima
分子名称: CHLORIDE ION, FLAVOPROTEIN, MU-OXO-DIIRON
著者Fang, H, Caranto, J.D, Taylor, A.B, Hart, P.J, Kurtz Jr, D.M.
登録日2012-01-31
公開日2012-10-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Histidine ligand variants of a flavo-diiron protein: effects on structure and activities.
J.Biol.Inorg.Chem., 17, 2012
4DIL
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BU of 4dil by Molmil
Flavo Di-iron protein H90N mutant from Thermotoga maritima
分子名称: CHLORIDE ION, FLAVOPROTEIN, MU-OXO-DIIRON
著者Fang, H, Caranto, J.D, Taylor, A.B, Hart, P.J, Kurtz, D.M.
登録日2012-01-31
公開日2012-10-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Histidine ligand variants of a flavo-diiron protein: effects on structure and activities.
J.Biol.Inorg.Chem., 17, 2012
8OXI
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BU of 8oxi by Molmil
crystal structure of powdery mildews Blumeria graminis f. sp. tritici AVRPM2(1)
分子名称: BgtE-5845_p
著者Cao, Y, Gebauer, J.M, Baumann, U, Chai, J.J.
登録日2023-05-02
公開日2023-08-16
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Structural polymorphisms within a common powdery mildew effector scaffold as a driver of coevolution with cereal immune receptors.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OXH
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BU of 8oxh by Molmil
crystal structure of powdery mildews Blumeria graminis f. sp. hordei AVRA6
分子名称: AVRA6
著者Cao, Y, Gebauer, J.M, Baumann, U, Chai, J.
登録日2023-05-02
公開日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural polymorphisms within a common powdery mildew effector scaffold as a driver of coevolution with cereal immune receptors.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OXL
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BU of 8oxl by Molmil
crystal structure of powdery mildews Blumeria graminis f. sp. hordei AVRA7
分子名称: AVRA7
著者Cao, Y, Gebauer, J.M, Baumann, U, Chai, J.J.
登録日2023-05-02
公開日2023-08-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Structural polymorphisms within a common powdery mildew effector scaffold as a driver of coevolution with cereal immune receptors.
Proc.Natl.Acad.Sci.USA, 120, 2023
8PHY
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BU of 8phy by Molmil
crystal structure of powdery mildews Blumeria graminis f. sp. tritici AVRPM2 (2)
分子名称: BgtE-5845_p
著者Cao, Y, Gebauer, J.M, Baumann, U, Chai, J.J.
登録日2023-06-20
公開日2023-08-16
実験手法X-RAY DIFFRACTION (1.06 Å)
主引用文献Structural polymorphisms within a common powdery mildew effector scaffold as a driver of coevolution with cereal immune receptors.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OXK
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BU of 8oxk by Molmil
crystal structure of powdery mildews Blumeria graminis f. sp. hordei AVRA10
分子名称: CSEP0141 putative effector protein
著者Cao, Y, Gebauer, J.M, Baumann, U, Chai, J.J.
登録日2023-05-02
公開日2023-08-16
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Structural polymorphisms within a common powdery mildew effector scaffold as a driver of coevolution with cereal immune receptors.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OXJ
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BU of 8oxj by Molmil
crystal structure of powdery mildews Blumeria graminis f. sp. hordei AVRA22
分子名称: AVRA22
著者Cao, Y, Gebaure, J.M, Baumann, U, Chai, J.J.
登録日2023-05-02
公開日2023-08-16
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Structural polymorphisms within a common powdery mildew effector scaffold as a driver of coevolution with cereal immune receptors.
Proc.Natl.Acad.Sci.USA, 120, 2023
8PFI
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BU of 8pfi by Molmil
Crystal structure of human TLR8 in complex with compound 34
分子名称: (3~{S})-~{N}-[4-[[5-(1,6-dimethylpyrazolo[3,4-b]pyridin-4-yl)-3-methyl-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridin-1-yl]methyl]-1-bicyclo[2.2.2]octanyl]morpholine-3-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 8, ...
著者Faller, M, Zink, F.
登録日2023-06-16
公開日2023-08-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.785 Å)
主引用文献Discovery of the TLR7/8 Antagonist MHV370 for Treatment of Systemic Autoimmune Diseases.
Acs Med.Chem.Lett., 14, 2023
4CEV
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BU of 4cev by Molmil
ARGINASE FROM BACILLUS CALDEVELOX, L-ORNITHINE COMPLEX
分子名称: GUANIDINE, L-ornithine, MANGANESE (II) ION, ...
著者Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N.
登録日1999-03-15
公開日1999-04-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily.
Structure Fold.Des., 7, 1999
8PBG
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BU of 8pbg by Molmil
Mutant K1556T of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoroorotate
分子名称: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
著者del Cano-Ochoa, F, Ramon-Maiques, S.
登録日2023-06-09
公開日2023-11-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBP
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BU of 8pbp by Molmil
Mutant R1785C of the dihydroorotase domain of human CAD protein bound to the substrate carbamoyl aspartate
分子名称: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
著者del Cano-Ochoa, F, Ramon-Maiques, S.
登録日2023-06-09
公開日2023-11-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBE
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BU of 8pbe by Molmil
Mutant K1556T of the dihydroorotase domain of human CAD protein bound to the substrate carbamoyl aspartate
分子名称: CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ...
著者del Cano-Ochoa, F, Ramon-Maiques, S.
登録日2023-06-09
公開日2023-11-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBI
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BU of 8pbi by Molmil
Mutant R1617Q of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoroorotate
分子名称: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
著者del Cano-Ochoa, F, Ramon-Maiques, S.
登録日2023-06-09
公開日2023-11-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBM
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BU of 8pbm by Molmil
Mutant R1789Q of the dihydroorotase domain of human CAD protein bound to the substrate dihydroorotate
分子名称: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
著者del Cano-Ochoa, F, Ramon-Maiques, S.
登録日2023-06-09
公開日2023-11-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBQ
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BU of 8pbq by Molmil
Mutant R1810Q of the dihydroorotase domain of human CAD protein bound to the substrates
分子名称: CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ...
著者del Cano-Ochoa, F, Ramon-Maiques, S.
登録日2023-06-09
公開日2023-11-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBR
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BU of 8pbr by Molmil
Mutant R1475Q of the dihydroorotase domain of human CAD protein in apo form
分子名称: CAD protein, FORMIC ACID, ZINC ION
著者del Cano-Ochoa, F, Ramon-Maiques, S.
登録日2023-06-09
公開日2023-11-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBJ
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BU of 8pbj by Molmil
Mutant R1722W of the dihydroorotase domain of human CAD protein bound to the substrate carbamoyl aspartate
分子名称: CAD protein, FORMIC ACID, GLYCEROL, ...
著者del Cano-Ochoa, F, Ramon-Maiques, S.
登録日2023-06-09
公開日2023-11-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBN
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BU of 8pbn by Molmil
Mutant R1789Q of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoorotate
分子名称: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
著者del Cano-Ochoa, F, Ramon-Maiques, S.
登録日2023-06-09
公開日2023-11-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBT
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BU of 8pbt by Molmil
Mutant K1482M of the dihydroorotase domain of human CAD protein bound to the substrate dihydroorotate
分子名称: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
著者del Cano-Ochoa, F, Ramon-Maiques, S.
登録日2023-06-09
公開日2023-11-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBU
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BU of 8pbu by Molmil
Mutant K1482M of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoorotate
分子名称: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
著者del Cano-Ochoa, F, Ramon-Maiques, S.
登録日2023-06-09
公開日2023-11-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023

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