PDB: 66478 件ウェブページステータス検索Chemie searchBIRD

---

3NNU	Crystal structure of P38 alpha in complex with DP1376 分子名称: 2-{3-[(5E)-5-{[(2,3-dichlorophenyl)carbamoyl]imino}-3-thiophen-2-yl-2,5-dihydro-1H-pyrazol-1-yl]phenyl}acetamide, Mitogen-activated protein kinase 14 著者 Abendroth, J. 登録日 2010-06-24 公開日 2010-09-15 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Switch control pocket inhibitors of p38-MAP kinase. Durable type II inhibitors that do not require binding into the canonical ATP hinge region Bioorg.Med.Chem.Lett., 20, 2010
1XB3	The D62C/K74C double mutant of Pseudomonas Aeruginosa Azurin 分子名称: Azurin, COPPER (II) ION 著者 Tigerstrom, A, Schwarz, F, Karlsson, G, Okvist, M, Alvarez-Rua, C, Maeder, D, Robb, F.T, Sjolin, L. 登録日 2004-08-27 公開日 2004-10-19 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.501 Å) 主引用文献 Effects of a novel disulfide bond and engineered electrostatic interactions on the thermostability of azurin Biochemistry, 43, 2004
3NNW	Crystal structure of P38 alpha in complex with DP802 分子名称: 2-[3-(3-tert-butyl-5-{[(2,3-dichlorophenyl)carbamoyl]imino}-2,5-dihydro-1H-pyrazol-1-yl)phenyl]acetamide, Mitogen-activated protein kinase 14 著者 Abendroth, J. 登録日 2010-06-24 公開日 2010-09-15 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Switch control pocket inhibitors of p38-MAP kinase. Durable type II inhibitors that do not require binding into the canonical ATP hinge region Bioorg.Med.Chem.Lett., 20, 2010
4QDL	Crystal structure of E.coli Cas1-Cas2 complex 分子名称: CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2 著者 Tamulaitiene, G, Sinkunas, T, Silanskas, A, Gasiunas, G, Grazulis, S, Siksnys, V. 登録日 2014-05-14 公開日 2014-05-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of E.coli Cas1-Cas2 complex To be Published
1W5Y	HIV-1 protease in complex with fluoro substituted diol-based C2- symmetric inhibitor 分子名称: (2R,3R,4R,5R)-2,5-BIS[(2,5-DIFLUOROBENZYL)OXY]-3,4-DIHYDROXY-N,N'-BIS[(1S,2R)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YL]HEXANEDIAMIDE, POL POLYPROTEIN 著者 Lindberg, J, Pyring, D, Loewgren, S, Rosenquist, A, Zuccarello, G, Kvarnstroem, I, Zhang, H, Vrang, L, Claesson, B, Hallberg, A, Samuelsson, B, Unge, T. 登録日 2004-08-10 公開日 2004-10-07 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Symmetric Fluoro-Substituted Diol-Based HIV Protease Inhibitors. Ortho-Fluorinated and Meta-Fluorinated P1/P1'-Benzyloxy Side Groups Significantly Improve the Antiviral Activity and Preserve Binding Efficacy Eur.J.Biochem., 271, 2004
4PC3	Elongation factor Tu:Ts complex with partially bound GDP 分子名称: Elongation factor Ts, Elongation factor Tu 1, GLYCEROL, ... 著者 Thirup, S.S. 登録日 2014-04-14 公開日 2015-05-06 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.8313 Å) 主引用文献 Structural outline of the detailed mechanism for elongation factor Ts-mediated guanine nucleotide exchange on elongation factor Tu. J.Struct.Biol., 191, 2015
4PC7	Elongation factor Tu:Ts complex in a near GTP conformation. 分子名称: (1S,2S,3E,5E,7E,10S,11S,12S)-12-[(2R,4E,6E,8Z,10R,12E,14E,16Z,18S,19Z)-10,18-DIHYDROXY-12,16,19-TRIMETHYL-11,22-DIOXOOX ACYCLODOCOSA-4,6,8,12,14,16,19-HEPTAEN-2-YL]-2,11-DIHYDROXY-1,10-DIMETHYL-9-OXOTRIDECA-3,5,7-TRIEN-1-YL 6-DEOXY-2,4-DI-O-METHYL-BETA-L-GALACTOPYRANOSIDE, Elongation factor Ts, Elongation factor Tu 1, ... 著者 Thirup, S.S. 登録日 2014-04-14 公開日 2015-05-06 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.6003 Å) 主引用文献 Structural outline of the detailed mechanism for elongation factor Ts-mediated guanine nucleotide exchange on elongation factor Tu. J.Struct.Biol., 191, 2015
5T9J	Crystal Structure of human GEN1 in complex with Holliday junction DNA in the upper interface 分子名称: DNA (5'-D(*DAP*DCP*DGP*DAP*DTP*DGP*DGP*DAP*DGP*DCP*DCP*DGP*DCP*DTP*DAP*DGP*DGP*DCP*DTP*DC)-3'), DNA (5'-D(*DGP*DAP*DAP*DTP*DTP*DCP*DCP*DGP*DGP*DAP*DTP*DTP*DAP*DGP*DGP*DGP*DAP*DTP*DGP*DC)-3'), DNA (5'-D(*DGP*DAP*DGP*DCP*DCP*DTP*DAP*DGP*DCP*DGP*DTP*DCP*DCP*DGP*DGP*DAP*DAP*DTP*DTP*DC)-3'), ... 著者 Lee, S.-H, Biertumpfel, C. 登録日 2016-09-09 公開日 2016-09-21 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.00012732 Å) 主引用文献 Human Holliday junction resolvase GEN1 uses a chromodomain for efficient DNA recognition and cleavage. Elife, 4, 2015
5T7K	X-ray crystal structure of AA13 LPMO 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, AoAA13, ZINC ION 著者 Frandsen, K.E.H, Poulsen, J.-C.N, Tovborg, M, Johansen, K.S, Lo Leggio, L. 登録日 2016-09-05 公開日 2017-01-18 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Learning from oligosaccharide soaks of crystals of an AA13 lytic polysaccharide monooxygenase: crystal packing, ligand binding and active-site disorder. Acta Crystallogr D Struct Biol, 73, 2017
1W07	Arabidopsis thaliana acyl-CoA oxidase 1 分子名称: ACYL-COA OXIDASE, CALCIUM ION, CHLORIDE ION, ... 著者 Henriksen, A, Pedersen, L. 登録日 2004-06-01 公開日 2004-12-15 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Acyl-Coa Oxidase 1 from Arabidopsis Thaliana. Structure of a Key Enzyme in Plant Lipid Metabolism J.Mol.Biol., 345, 2005
1W69	Crystal Structure of Mouse Ribonucleotide Reductase Subunit R2 under Reducing Conditions. A Fully Occupied Dinuclear Iron Cluster and Bound Acetate. 分子名称: ACETIC ACID, FE (II) ION, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE M2 CHAIN 著者 Karlsen, S, Strand, K.R, Kolberg, M, Rohr, A.K, Gorbitz, C.H, Andersson, K.K. 登録日 2004-08-16 公開日 2004-08-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structural Studies of Changes in the Native Dinuclear Iron Center of Ribonucleotide Reductase Protein R2 from Mouse J.Biol.Chem., 279, 2004
3OBJ	Conformational plasticity of p38 MAP kinase DFG mutants in response to inhibitor binding 分子名称: 1-(5-TERT-BUTYL-2-METHYL-2H-PYRAZOL-3-YL)-3-(4-CHLORO-PHENYL)-UREA, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside 著者 Namboodiri, H.V, Karpusas, M, Bukhtiyarova, M, Springman, E.B. 登録日 2010-08-06 公開日 2010-08-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor binding To be Published
4QF9	Structure of GluK1 ligand-binding domain (S1S2) in complex with (S)-2-amino-4-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)butanoic acid at 2.28 A resolution 分子名称: (2S)-2-amino-4-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)butanoic acid, ACETATE ION, CHLORIDE ION, ... 著者 Kristensen, C.M, Frydenvang, K, Kastrup, J.S. 登録日 2014-05-20 公開日 2015-04-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Binding Mode of an alpha-Amino Acid-Linked Quinoxaline-2,3-dione Analogue at Glutamate Receptor Subtype GluK1. ACS Chem Neurosci, 6, 2015
1XTU	Sulfolobus solfataricus uracil phosphoribosyltransferase in complex with uridine 5'-monophosphate (UMP) and cytidine 5'-triphosphate (CTP) 分子名称: CYTIDINE-5'-TRIPHOSPHATE, Probable uracil phosphoribosyltransferase, URIDINE-5'-MONOPHOSPHATE 著者 Arent, S, Harris, P, Jensen, K.F, Larsen, S. 登録日 2004-10-24 公開日 2005-02-08 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Allosteric Regulation and Communication between Subunits in Uracil Phosphoribosyltransferase from Sulfolobus solfataricus(,) Biochemistry, 44, 2005
4P2Y	Crystal structure of the human RAGE ectodomain (fragment VC1C2) in complex with mouse S100A6 分子名称: ACETATE ION, Advanced glycosylation end product-specific receptor, CALCIUM ION, ... 著者 Yatime, L, Andersen, G.R. 登録日 2014-03-05 公開日 2015-03-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The Structure of the RAGE:S100A6 Complex Reveals a Unique Mode of Homodimerization for S100 Proteins. Structure, 2016
1XTT	Sulfolobus solfataricus uracil phosphoribosyltransferase in complex with uridine 5'-monophosphate (UMP) 分子名称: ACETIC ACID, Probable uracil phosphoribosyltransferase, URIDINE-5'-MONOPHOSPHATE 著者 Arent, S, Harris, P, Jensen, K.F, Larsen, S. 登録日 2004-10-24 公開日 2005-02-08 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Allosteric Regulation and Communication between Subunits in Uracil Phosphoribosyltransferase from Sulfolobus solfataricus(,) Biochemistry, 44, 2005
1XS1	dCTP deaminase from Escherichia coli in complex with dUTP 分子名称: DEOXYURIDINE-5'-TRIPHOSPHATE, Deoxycytidine triphosphate deaminase, MAGNESIUM ION 著者 Johansson, E, Fano, M, Bynck, J.H, Neuhard, J, Larsen, S, Sigurskjold, B.W, Christensen, U, Willemoes, M. 登録日 2004-10-18 公開日 2004-12-21 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of dCTP deaminase from Escherichia coli with bound substrate and product: reaction mechanism and determinants of mono- and bifunctionality for a family of enzymes J.Biol.Chem., 280, 2005
1XTV	Sulfolobus solfataricus uracil phosphoribosyltransferase with uridine 5'-monophosphate (UMP) bound to half of the subunits 分子名称: Probable uracil phosphoribosyltransferase, URIDINE-5'-MONOPHOSPHATE 著者 Arent, S, Harris, P, Jensen, K.F, Larsen, S. 登録日 2004-10-24 公開日 2005-02-08 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Allosteric Regulation and Communication between Subunits in Uracil Phosphoribosyltransferase from Sulfolobus solfataricus(,) Biochemistry, 44, 2005
4PO7	Structure of the Sortilin:neurotensin complex at excess neurotensin concentration 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Neurotensin/neuromedin N, Sortilin, ... 著者 Quistgaard, E.M, Groftehauge, M.K, Thirup, S.S. 登録日 2014-02-25 公開日 2014-07-23 最終更新日 2020-10-21 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Revisiting the structure of the Vps10 domain of human sortilin and its interaction with neurotensin. Protein Sci., 23, 2014
4P3B	Crystal structure of the mouse C5a-desArg anaphylatoxin 分子名称: Complement C5, FORMIC ACID 著者 Yatime, L, Schatz-Jakobsen, J.A, Andersen, G.R. 登録日 2014-03-06 公開日 2014-06-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and functional characterization of human and murine C5a anaphylatoxins. Acta Crystallogr. D Biol. Crystallogr., 70, 2014
3MPT	Crystal structure of P38 kinase in complex with a pyrrole-2-carboxamide inhibitor 分子名称: GLYCEROL, Mitogen-activated protein kinase 14, N-(furan-2-ylmethyl)-4-[(2-methylphenyl)carbonyl]-1H-pyrrole-2-carboxamide 著者 Somers, D.O. 登録日 2010-04-27 公開日 2010-07-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 The discovery and initial optimisation of pyrrole-2-carboxamides as inhibitors of p38alpha MAP kinase. Bioorg.Med.Chem.Lett., 20, 2010
4P3A	Crystal structure of the mouse C5a anaphylatoxin 分子名称: Complement C5, FORMIC ACID 著者 Yatime, L, Schatz-Jakobsen, J.A, Andersen, G.R. 登録日 2014-03-06 公開日 2014-06-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural and functional characterization of human and murine C5a anaphylatoxins. Acta Crystallogr. D Biol. Crystallogr., 70, 2014
1XR8	Crystal Structures of HLA-B*1501 in Complex with Peptides from Human UbcH6 and Epstein-Barr Virus EBNA-3 分子名称: Beta-2-microglobulin, EBNA-3 nuclear protein, GLYCEROL, ... 著者 Roder, G, Blicher, T, Johannessen, B.R, Kristensen, O, Buus, S, Gajhede, M. 登録日 2004-10-14 公開日 2005-04-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structures of two peptide-HLA-B*1501 complexes; structural characterization of the HLA-B62 supertype Acta Crystallogr.,Sect.D, 62, 2006
1ZWS	Crystal structure of the catalytic domain of human DRP-1 kinase 分子名称: DAP-kinase related protein 1 著者 Kursula, P, Schunck, H, Wilmanns, M. 登録日 2005-06-06 公開日 2006-10-24 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structure of the catalytic domain of human DRP-1 kinase To be Published
1ZS2	Amylosucrase Mutant E328Q in a ternary complex with sucrose and maltoheptaose 分子名称: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, amylosucrase, ... 著者 Skov, L.K, Mirza, O, Sprogoe, D, van der Veen, B.A, Remaud-Simeon, M, Albenne, C, Monsan, P, Gajhede, M. 登録日 2005-05-23 公開日 2006-05-02 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Crystal structure of the Glu328Gln mutant of Neisseria polysaccharea amylosucrase in complex with sucrose and maltoheptaose BIOCATAL.BIOTRANSFOR., 24, 2006

<144145146147148149150151152153154155156157158159>