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5OU1
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M. thermoresistible IMPDH in complex with IMP and Compound 1 (7759844)
分子名称: (2~{S})-~{N}-(4-iodophenyl)-2-(4-methoxyphenoxy)propanamide, INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase
著者Ascher, D.B, Pacitto, A, Blundell, T.L.
登録日2017-08-23
公開日2018-03-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Fragment-Based Approach to Targeting Inosine-5'-monophosphate Dehydrogenase (IMPDH) from Mycobacterium tuberculosis.
J. Med. Chem., 61, 2018
5OU3
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M. thermoresistible IMPDH in complex with IMP and Compound 31 (AT080)
分子名称: (2~{S})-~{N}-[5-(4-bromophenyl)-1~{H}-imidazol-2-yl]-2-[4-(1-methylimidazol-4-yl)phenoxy]propanamide, INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase
著者Ascher, D.B, Pacitto, A, Blundell, T.L.
登録日2017-08-23
公開日2018-03-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Fragment-Based Approach to Targeting Inosine-5'-monophosphate Dehydrogenase (IMPDH) from Mycobacterium tuberculosis.
J. Med. Chem., 61, 2018
6N14
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BU of 6n14 by Molmil
Phosphoserine BlaC, Class A serine beta-lactamase from Mycobacterium tuberculosis
分子名称: Beta-lactamase, PHOSPHATE ION
著者Moural, T.W, White, D.S, Choy, C.J, Kang, C, Berkman, C.E.
登録日2018-11-08
公開日2019-08-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.52169466 Å)
主引用文献Crystal Structure of Phosphoserine BlaC fromMycobacterium tuberculosisInactivated by Bis(Benzoyl) Phosphate.
Int J Mol Sci, 20, 2019
6GAV
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BU of 6gav by Molmil
Extremely 'open' clamp structure of DNA gyrase: role of the Corynebacteriales GyrB specific insert
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA gyrase subunit B,DNA gyrase subunit A
著者Petrella, S, Capton, E, Alzari, P.M, Aubry, A, MAyer, C.
登録日2018-04-12
公開日2019-02-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Overall Structures of Mycobacterium tuberculosis DNA Gyrase Reveal the Role of a Corynebacteriales GyrB-Specific Insert in ATPase Activity.
Structure, 27, 2019
5ZET
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BU of 5zet by Molmil
M. smegmatis P/P state 50S ribosomal subunit
分子名称: 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ...
著者Mishra, S, Ahmed, T, Tyagi, A, Shi, J, Bhushan, S.
登録日2018-02-28
公開日2018-09-26
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structures of Mycobacterium smegmatis 70S ribosomes in complex with HPF, tmRNA, and P-tRNA.
Sci Rep, 8, 2018
4KL7
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BU of 4kl7 by Molmil
Crystal structure of the catalytic domain of RpfB from Mycobacterium tuberculosis
分子名称: Resuscitation-promoting factor RpfB, SULFATE ION
著者Squeglia, F, Romano, M, Ruggiero, A, Berisio, R.
登録日2013-05-07
公開日2013-06-26
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Carbohydrate Recognition by RpfB from Mycobacterium tuberculosis Unveiled by Crystallographic and Molecular Dynamics Analyses.
Biophys.J., 104, 2013
1SBQ
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BU of 1sbq by Molmil
Crystal Structure of methenyltetrahydrofolate synthetase from Mycoplasma pneumoniae at 2.2 resolution
分子名称: 5,10-Methenyltetrahydrofolate synthetase homolog, SULFATE ION
著者Chen, S, Shin, D.H, Pufan, R, Kim, R, Kim, S.H, Berkeley Structural Genomics Center (BSGC)
登録日2004-02-10
公開日2004-08-10
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of methenyltetrahydrofolate synthetase from Mycoplasma pneumoniae (GI: 13508087) at 2.2 A resolution
Proteins, 56, 2004
4KPM
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BU of 4kpm by Molmil
Crystal structure of the catalytic domain of RpfB from Mycobacterium tuberculosis in complex with triNAG
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BENZAMIDINE, Resuscitation-promoting factor RpfB, ...
著者Squeglia, F, Ruggiero, A, Berisio, R.
登録日2013-05-14
公開日2013-06-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Carbohydrate Recognition by RpfB from Mycobacterium tuberculosis Unveiled by Crystallographic and Molecular Dynamics Analyses.
Biophys.J., 104, 2013
1SE6
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BU of 1se6 by Molmil
Crystal Structure of Streptomyces Coelicolor A3(2) CYP158A2 from antibiotic biosynthetic pathways
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, PROTOPORPHYRIN IX CONTAINING FE, SPERMINE (FULLY PROTONATED FORM), ...
著者Zhao, B, Lamb, D.C, Lei, L, Sundaramoorthy, M, Podust, L.M, Waterman, M.R.
登録日2004-02-16
公開日2005-01-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Binding of Two Flaviolin Substrate Molecules, Oxidative Coupling, and Crystal Structure of Streptomyces coelicolor A3(2) Cytochrome P450 158A2.
J.Biol.Chem., 280, 2005
8SLF
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BU of 8slf by Molmil
Crystal Structure of Glycine tRNA ligase from Mycobacterium thermoresistibile (AMP bound)
分子名称: ADENOSINE MONOPHOSPHATE, Glycine--tRNA ligase, MAGNESIUM ION, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-04-21
公開日2023-05-03
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structure of Glycine tRNA ligase from Mycobacterium thermoresistibile (AMP bound)
To be published
5OAY
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BU of 5oay by Molmil
M. tuberculosis [4Fe-4S] protein WhiB1 is a four-helix bundle that forms a NO-sensitive complex with sigmaA and regulates the major virulence factor ESX-1
分子名称: IRON/SULFUR CLUSTER, Transcriptional regulator WhiB1
著者Williamson, M.P, Green, J, Hounslow, A.M.
登録日2017-06-25
公開日2018-01-03
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of a Wbl protein and implications for NO sensing by M. tuberculosis.
Nat Commun, 8, 2017
5TS1
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BU of 5ts1 by Molmil
Crystal structure of MHC-I H2-KD complexed with peptides of Mycobacterial tuberculosis (YYQSGLSIV)
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Jiang, J, Natarajan, K, Margulies, D.
登録日2016-10-27
公開日2018-05-09
最終更新日2020-02-05
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献MHC-restricted Ag85B-specific CD8+T cells are enhanced by recombinant BCG prime and DNA boost immunization in mice.
Eur.J.Immunol., 2019
7K62
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BU of 7k62 by Molmil
Crystal Structure of Dihydrofolate reductase from Mycobacterium kansasii in complex with NADP and inhibitor P218
分子名称: 1,2-ETHANEDIOL, 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid, Dihydrofolate reductase, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2020-09-18
公開日2021-03-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal Structure of Dihydrofolate reductase from Mycobacterium kansasii in complex with NADP and inhibitor P218
To Be Published
7K6C
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BU of 7k6c by Molmil
Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium abscessus ATCC 19977 / DSM 44196 with NADP and inhibitor P218
分子名称: 1,2-ETHANEDIOL, 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid, CALCIUM ION, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2020-09-19
公開日2021-03-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium abscessus ATCC 19977 / DSM 44196 with NADP and inhibitor P218
to be published
7K6A
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BU of 7k6a by Molmil
Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor SDDC-0001575
分子名称: 1,2-ETHANEDIOL, 6-ethyl-5-[3-({3-[4-(trifluoromethyl)piperidin-1-yl]pyridin-2-yl}oxy)propoxy]pyrimidine-2,4-diamine, CHLORIDE ION, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2020-09-19
公開日2021-03-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor SDDC-0001575
to be published
7K69
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Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor SDDC-0001574
分子名称: 1-{2-[2-(2,4-diamino-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidin-6-yl)-2-oxoethoxy]phenyl}piperidine-4-carboxylic acid, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2020-09-19
公開日2021-03-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor SDDC-0001574
To Be Published
7K68
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BU of 7k68 by Molmil
Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor SDDC-0001565
分子名称: 3-(3-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid, CHLORIDE ION, Dihydrofolate reductase, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2020-09-19
公開日2021-03-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor SDDC-0001565
To Be Published
5TRZ
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BU of 5trz by Molmil
Crystal structure of MHC-I H2-KD complexed with peptides of Mycobacterial tuberculosis (YQSGLSIVM)
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Jiang, J, Natarajan, K, Margulies, D.
登録日2016-10-27
公開日2018-05-09
最終更新日2019-08-14
実験手法X-RAY DIFFRACTION (2.247 Å)
主引用文献MHC-restricted Ag85B-specific CD8+T cells are enhanced by recombinant BCG prime and DNA boost immunization in mice.
Eur.J.Immunol., 2019
5VO7
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BU of 5vo7 by Molmil
NMR Assignment and Structure of Thioredoxin (Rv1471 ortholog) from Mycobacterium smegmatis ATCC 700084 / mc(2)155
分子名称: Thioredoxin
著者Barnwal, R.P, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2017-05-02
公開日2017-06-07
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Assignment and Structure of Thioredoxin (Rv1471 ortholog) type protein from Mycobacterium smegmatis ATCC 700084 / mc(2)155
To Be Published
6Q1Y
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BU of 6q1y by Molmil
Crystal Structure of Enoyl-[acyl-carrier-protein] reductase from Mycobacterium avium with bound NAD
分子名称: 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2019-08-06
公開日2019-08-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal Structure of Enoyl-[acyl-carrier-protein] reductase from Mycobacterium avium with bound NAD
to be published
8RP3
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BU of 8rp3 by Molmil
Alpha-Methylacyl-CoA racemase from Mycobacterium tuberculosis (H126A mutant)
分子名称: 1,2-ETHANEDIOL, Alpha-methylacyl-CoA racemase
著者Mojanaga, O.O, Acharya, K.R, Lloyd, M.D.
登録日2024-01-12
公開日2024-04-10
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献alpha-Methylacyl-CoA Racemase from Mycobacterium tuberculosis -Detailed Kinetic and Structural Characterization of the Active Site.
Biomolecules, 14, 2024
8RP5
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BU of 8rp5 by Molmil
Alpha-Methylacyl-CoA racemase from Mycobacterium tuberculosis (E241A mutant)
分子名称: 1,2-ETHANEDIOL, Alpha-methylacyl-CoA racemase, TRIETHYLENE GLYCOL
著者Mojanaga, O.O, Acharya, K.R, Lloyd, M.D.
登録日2024-01-12
公開日2024-04-10
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献alpha-Methylacyl-CoA Racemase from Mycobacterium tuberculosis -Detailed Kinetic and Structural Characterization of the Active Site.
Biomolecules, 14, 2024
1ISZ
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BU of 1isz by Molmil
Crystal structure of xylanase from Streptomyces olivaceoviridis E-86 complexed with galactose
分子名称: beta-D-galactopyranose, endo-1,4-beta-D-xylanase
著者Fujimoto, Z, Kuno, A, Kaneko, S, Kobayashi, H, Kusakabe, I, Mizuno, H.
登録日2001-12-27
公開日2002-02-20
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of the sugar complexes of Streptomyces olivaceoviridis E-86 xylanase: sugar binding structure of the family 13 carbohydrate binding module.
J.Mol.Biol., 316, 2002
8RP4
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BU of 8rp4 by Molmil
Alpha-Methylacyl-CoA racemase from Mycobacterium tuberculosis (D156A mutant)
分子名称: 1,2-ETHANEDIOL, Alpha-methylacyl-CoA racemase, DI(HYDROXYETHYL)ETHER
著者Mojanaga, O.O, Acharya, K.R, Lloyd, M.D.
登録日2024-01-12
公開日2024-04-10
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献alpha-Methylacyl-CoA Racemase from Mycobacterium tuberculosis -Detailed Kinetic and Structural Characterization of the Active Site.
Biomolecules, 14, 2024
6GFV
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BU of 6gfv by Molmil
M tuberculosis LpqI
分子名称: Probable conserved lipoprotein LpqI
著者Moynihan, P.J, Lovering, A.L.
登録日2018-05-02
公開日2019-05-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献The hydrolase LpqI primes mycobacterial peptidoglycan recycling.
Nat Commun, 10, 2019

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件を2024-10-16に公開中

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