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3P8R
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CRYSTAL STRUCTURE OF POLYPRENYL SYNTHASE FROM Vibrio cholerae
分子名称: Geranyltranstransferase
著者Patskovsky, Y, Toro, R, Dickey, M, Sauder, J.M, Burley, S.K, Poulter, C.D, Gerlt, J.A, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2010-10-14
公開日2010-10-27
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Proc.Natl.Acad.Sci.USA, 110, 2013
1ILT
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BU of 1ilt by Molmil
X-RAY STRUCTURE OF INTERLEUKIN-1 RECEPTOR ANTAGONIST AT 2.0 ANGSTROMS RESOLUTION
分子名称: INTERLEUKIN-1 RECEPTOR ANTAGONIST
著者Brandhuber, B.J, Vigers, G.P.A.
登録日1994-03-09
公開日1995-04-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-ray structure of interleukin-1 receptor antagonist at 2.0-A resolution.
J.Biol.Chem., 269, 1994
3P9W
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Crystal structure of an engineered human autonomous VH Domain in complex with VEGF
分子名称: Vascular endothelial growth factor A, human VEGF
著者Ma, X, Wiesmann, C.
登録日2010-10-18
公開日2012-04-18
最終更新日2013-06-19
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Design of Synthetic Autonomous VH Domain Libraries and Structural Analysis of a VH Domain Bound to Vascular Endothelial Growth Factor.
J.Mol.Biol., 425, 2013
6D3O
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Crystal Structure of Vascular Endothelial Growth Factor (VEGF8-109) with HH4, an alpha/beta-Peptide with Irregular Secondary Structure
分子名称: HH4 alpha/beta-Peptide, Vascular endothelial growth factor A
著者Thomas, N.C, Forest, K.T, Gellman, S.H.
登録日2018-04-16
公開日2019-04-24
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献High-Resolution Structures for a Complex Between a Non-Helical Foldamer and VEGF
To Be Published
2FJG
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Structure of the G6 Fab, a phage derived Fab fragment, in complex with VEGF
分子名称: Fab heavy chain, Fab light chain, SULFATE ION, ...
著者Wiesmann, C.
登録日2006-01-02
公開日2006-02-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-function studies of two synthetic anti-vascular endothelial growth factor Fabs and comparison with the Avastin Fab.
J.Biol.Chem., 281, 2006
1ILR
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BU of 1ilr by Molmil
CRYSTAL STRUCTURE OF THE INTERLEUKIN-1 RECEPTOR ANTAGONIST
分子名称: INTERLEUKIN-1 RECEPTOR ANTAGONIST PROTEIN
著者Schreuder, H.A, Rondeau, J.-M, Tardif, C.
登録日1994-06-20
公開日1995-02-07
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Refined crystal structure of the interleukin-1 receptor antagonist. Presence of a disulfide link and a cis-proline.
Eur.J.Biochem., 227, 1995
2GPN
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BU of 2gpn by Molmil
100 K STRUCTURE OF GLYCOGEN PHOSPHORYLASE AT 2.0 ANGSTROMS RESOLUTION
分子名称: GLYCOGEN PHOSPHORYLASE B
著者Gregoriou, M, Noble, M.E.M, Watson, K.A, Garman, E.F, Krulle, T.M, De La Fuente, C, Fleet, G.W.J, Oikonomakos, N.G, Johnson, L.N.
登録日1998-03-26
公開日1998-07-01
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献The structure of a glycogen phosphorylase glucopyranose spirohydantoin complex at 1.8 A resolution and 100 K: the role of the water structure and its contribution to binding.
Protein Sci., 7, 1998
3OYR
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BU of 3oyr by Molmil
Crystal structure of polyprenyl synthase from Caulobacter crescentus CB15 complexed with calcium and isoprenyl diphosphate
分子名称: CALCIUM ION, DIMETHYLALLYL DIPHOSPHATE, PYROPHOSPHATE 2-, ...
著者Patskovsky, Y, Toro, R, Rutter, M, Sauder, J.M, Burley, S.K, Poulter, C.D, Gerlt, J.A, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2010-09-23
公開日2010-10-13
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Proc.Natl.Acad.Sci.USA, 110, 2013
3P8L
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Crystal structure of polyprenyl synthase from Enterococcus faecalis V583
分子名称: Geranyltranstransferase
著者Patskovsky, Y, Toro, R, Dickey, M, Sauder, J.M, Burley, S.K, Poulter, C.D, Gerlt, J.A, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2010-10-14
公開日2010-11-03
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Proc.Natl.Acad.Sci.USA, 110, 2013
1IRP
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BU of 1irp by Molmil
SOLUTION STRUCTURE OF HUMAN INTERLEUKIN-1 RECEPTOR ANTAGONIST PROTEIN
分子名称: INTERLEUKIN-1 RECEPTOR ANTAGONIST
著者Stockman, B.J, Scahill, T.A, Strakalaitis, N.A.
登録日1994-10-18
公開日1995-02-27
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of human interleukin-1 receptor antagonist protein.
FEBS Lett., 349, 1994
2F3S
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BU of 2f3s by Molmil
Crystal Structure of the glycogen phosphorylase B / ethyl-N-(beta-D-glucopyranosyl)oxamate complex
分子名称: Glycogen phosphorylase, muscle form, N-[ethoxy(oxo)acetyl]-beta-D-glucopyranosylamine, ...
著者Oikonomakos, N.G, Leonidas, D.D.
登録日2005-11-22
公開日2006-05-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Binding of oxalyl derivatives of beta-d-glucopyranosylamine to muscle glycogen phosphorylase b.
Bioorg.Med.Chem., 14, 2006
1IOB
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BU of 1iob by Molmil
INTERLEUKIN-1 BETA FROM JOINT X-RAY AND NMR REFINEMENT
分子名称: INTERLEUKIN-1 BETA
著者Shaanan, B, Clore, G.M.
登録日1996-03-14
公開日1996-08-17
最終更新日2024-05-01
実験手法SOLUTION NMR (2 Å), X-RAY DIFFRACTION
主引用文献Combining experimental information from crystal and solution studies: joint X-ray and NMR refinement.
Science, 257, 1992
3P41
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Crystal structure of polyprenyl synthetase from pseudomonas fluorescens pf-5 complexed with magnesium and isoprenyl pyrophosphate
分子名称: CHLORIDE ION, DIMETHYLALLYL DIPHOSPHATE, GLYCEROL, ...
著者Patskovsky, Y, Toro, R, Sauder, J.M, Burley, S.K, Poulter, C.D, Gerlt, J.A, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2010-10-05
公開日2010-10-20
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Proc.Natl.Acad.Sci.USA, 110, 2013
3QKI
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BU of 3qki by Molmil
Crystal structure of Glucose-6-Phosphate Isomerase (PF14_0341) from Plasmodium falciparum 3D7
分子名称: Glucose-6-phosphate isomerase
著者Gileadi, T, Wernimont, A.K, Hutchinson, A, Weadge, J, Cossar, D, Lew, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Hui, R, Hills, T, Pizarro, J.C, Structural Genomics Consortium (SGC)
登録日2011-02-01
公開日2011-02-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Crystal structure of Glucose-6-Phosphate Isomerase (PF14_0341) from Plasmodium falciparum 3D7
TO BE PUBLISHED
2G9U
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BU of 2g9u by Molmil
The crystal structure of glycogen phosphorylase in complex with (3R,4R,5R)-5-hydroxymethyl-1-(3-phenylpropyl)-piperidine-3,4-diol and phosphate
分子名称: (3R,4R,5R)-5-(HYDROXYMETHYL)-1-(3-PHENYLPROPYL)PIPERIDINE-3,4-DIOL, Glycogen phosphorylase, muscle form, ...
著者Oikonomakos, N.G, Tiraidis, C, Leonidas, D.D, Zographos, S.E.
登録日2006-03-07
公開日2007-01-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Iminosugars as potential inhibitors of glycogenolysis: structural insights into the molecular basis of glycogen phosphorylase inhibition.
J.Med.Chem., 49, 2006
2G9V
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BU of 2g9v by Molmil
The crystal structure of glycogen phosphorylase in complex with (3R,4R,5R)-5-hydroxymethylpiperidine-3,4-diol and phosphate
分子名称: 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, Glycogen phosphorylase, muscle form, ...
著者Oikonomakos, N.G, Tiraidis, C, Leonidas, D.D, Zographos, S.E.
登録日2006-03-07
公開日2007-01-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Iminosugars as potential inhibitors of glycogenolysis: structural insights into the molecular basis of glycogen phosphorylase inhibition.
J.Med.Chem., 49, 2006
3QTK
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BU of 3qtk by Molmil
The crystal structure of chemically synthesized VEGF-A
分子名称: ACETATE ION, GLYCEROL, Vascular endothelial growth factor A, ...
著者Mandal, K, Kent, S.B.H.
登録日2011-02-22
公開日2011-07-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.849 Å)
主引用文献Total chemical synthesis of biologically active vascular endothelial growth factor.
Angew.Chem.Int.Ed.Engl., 50, 2011
1JIQ
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BU of 1jiq by Molmil
Crystal Structure of Human Autocrine Motility Factor
分子名称: autocrine motility factor
著者Tanaka, N, Haga, A, Uemura, H, Akiyama, H, Funasaka, T, Nagase, H, Raz, A, Nakamura, K.T.
登録日2001-07-02
公開日2002-06-19
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Inhibition mechanism of cytokine activity of human autocrine motility factor examined by crystal structure analyses and site-directed mutagenesis studies.
J.Mol.Biol., 318, 2002
2FOR
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BU of 2for by Molmil
Crystal Structure of the Shigella flexneri Farnesyl Pyrophosphate Synthase Complex with an Isopentenyl Pyrophosphate
分子名称: Geranyltranstransferase, ISOPENTYL PYROPHOSPHATE, PHOSPHATE ION
著者Minasov, G, Brunzelle, J.S, Shuvalova, L, Collart, F.R, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG)
登録日2006-01-13
公開日2006-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the Shigella flexneri Farnesyl Pyrophosphate Synthase Complex with an Isopentenyl Pyrophosphate
To be Published
1K08
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Crystallographic Binding Study of 10 mM N-benzoyl-N'-beta-D-glucopyranosyl urea to glycogen phosphorylase b
分子名称: Glycogen Phosphorylase, N-[(phenylcarbonyl)carbamoyl]-beta-D-glucopyranosylamine, PYRIDOXAL-5'-PHOSPHATE
著者Oikonomakos, N.G, Kosmopoulou, M, Zographos, S.E, Leonidas, D.D, Chrysina, E.D, Somsak, L, Nagy, V, Praly, J.P, Docsa, T, Toth, B, Gergely, P.
登録日2001-09-18
公開日2001-10-03
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Binding of N-acetyl-N '-beta-D-glucopyranosyl urea and N-benzoyl-N '-beta-D-glucopyranosyl urea to glycogen phosphorylase b: kinetic and crystallographic studies.
Eur.J.Biochem., 269, 2002
3PH7
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Crystal structure of Plasmodium vivax putative polyprenyl pyrophosphate synthase in complex with geranylgeranyl diphosphate
分子名称: Farnesyl pyrophosphate synthase, GERANYLGERANYL DIPHOSPHATE
著者Wernimont, A.K, Dunford, J, Lew, J, Zhao, Y, Kozieradzki, I, Cossar, D, Schapiro, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Artz, J.D, Structural Genomics Consortium (SGC)
登録日2010-11-03
公開日2010-11-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular characterization of a novel geranylgeranyl pyrophosphate synthase from Plasmodium parasites.
J.Biol.Chem., 286, 2011
3POK
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Interleukin-1-beta LBT L3 Mutant
分子名称: Interleukin-1 beta
著者Barthelmes, K, Reynolds, A.M, Peisach, E, Jonker, H.R.A, DeNunzio, N.J, Allen, K.N, Imperiali, B, Schwalbe, H.
登録日2010-11-22
公開日2011-01-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Engineering encodable lanthanide-binding tags into loop regions of proteins.
J.Am.Chem.Soc., 133, 2011
3Q2Q
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Crystal structure of geranylgeranyl pyrophosphate synthase from Corynebacterium glutamicum complexed with calcium and isoprenyl diphosphate
分子名称: CALCIUM ION, DIMETHYLALLYL DIPHOSPHATE, GLYCEROL, ...
著者Patskovsky, Y, Toro, R, Rutter, M, Sauder, J.M, Poulter, C.D, Gerlt, J.A, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2010-12-20
公開日2011-01-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Proc.Natl.Acad.Sci.USA, 110, 2013
2H8O
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The 1.6A crystal structure of the geranyltransferase from Agrobacterium tumefaciens
分子名称: Geranyltranstransferase
著者Zhang, R, Xu, X, Gu, J, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2006-06-07
公開日2006-07-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The 1.6A crystal structure of the geranyltransferase from Agrobacterium tumefaciens
To be Published
3PDE
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Crystal structure of geranylgeranyl pyrophosphate synthase from Lactobacillus brevis atcc 367 complexed with isoprenyl diphosphate and magnesium
分子名称: DIMETHYLALLYL DIPHOSPHATE, Farnesyl-diphosphate synthase, GLYCEROL, ...
著者Patskovsky, Y, Toro, R, Rutter, M, Sauder, J.M, Burley, S.K, Poulter, C.D, Gerlt, J.A, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2010-10-22
公開日2010-11-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Proc.Natl.Acad.Sci.USA, 110, 2013

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