PDB: 597 件ウェブページステータス検索Chemie searchBIRD

---

5ZC9	Crystal structure of the human eIF4A1-ATP analog-RocA-polypurine RNA complex 分子名称: (1R,2R,3S,3aR,8bS)-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-1,8b-bis(oxidanyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxamide, Eukaryotic initiation factor 4A-I, MAGNESIUM ION, ... 著者 Iwasaki, W, Takahashi, M, Sakamoto, A, Iwasaki, S, Ito, T. 登録日 2018-02-16 公開日 2019-01-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The Translation Inhibitor Rocaglamide Targets a Bimolecular Cavity between eIF4A and Polypurine RNA. Mol. Cell, 73, 2019
5ZBZ	Crystal structure of the DEAD domain of Human eIF4A with sanguinarine 分子名称: 13-methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridin-13-ium, Eukaryotic initiation factor 4A-I, MALONATE ION 著者 Ding, Y, Ding, L. 登録日 2018-02-14 公開日 2019-02-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.30860257 Å) 主引用文献 Targeting the N Terminus of eIF4AI for Inhibition of Its Catalytic Recycling. Cell Chem Biol, 26, 2019
5ZAM	Cryo-EM structure of human Dicer and its complexes with a pre-miRNA substrate 分子名称: Endoribonuclease Dicer, RISC-loading complex subunit TARBP2, RNA (73-mer) 著者 Liu, Z, Wang, J, Cheng, H, Ke, X, Sun, L, Zhang, Q.C, Wang, H.-W. 登録日 2018-02-07 公開日 2018-05-09 最終更新日 2020-08-05 実験手法 ELECTRON MICROSCOPY (5.7 Å) 主引用文献 Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate. Cell, 173, 2018
5ZAL	Cryo-EM structure of human Dicer and its complexes with a pre-miRNA substrate 分子名称: Endoribonuclease Dicer, RISC-loading complex subunit TARBP2, RNA (73-mer) 著者 Liu, Z, Wang, J, Cheng, H, Ke, X, Sun, L, Zhang, Q.C, Wang, H.-W. 登録日 2018-02-07 公開日 2018-05-09 最終更新日 2020-08-05 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate. Cell, 173, 2018
5ZAK	Cryo-EM structure of human Dicer and its complexes with a pre-miRNA substrate 分子名称: Endoribonuclease Dicer, RISC-loading complex subunit TARBP2 著者 Liu, Z, Wang, J, Cheng, H, Ke, X, Sun, L, Zhang, Q.C, Wang, H.-W. 登録日 2018-02-07 公開日 2018-05-09 最終更新日 2019-11-06 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate. Cell, 173, 2018
6CB1	Yeast nucleolar pre-60S ribosomal subunit (state 3) 分子名称: 35S pre-ribosomal RNA miscRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... 著者 Sanghai, Z.A, Miller, L, Barandun, J, Hunziker, M, Chaker-Margot, M, Klinge, S. 登録日 2018-02-01 公開日 2018-03-14 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Modular assembly of the nucleolar pre-60S ribosomal subunit. Nature, 556, 2018
6C90	Human Mtr4 helicase in complex with ZCCHC8-CTD 分子名称: ADENOSINE-5'-DIPHOSPHATE, Exosome RNA helicase MTR4,Exosome RNA helicase MTR4, L(+)-TARTARIC ACID, ... 著者 Puno, M.R, Lima, C.D. 登録日 2018-01-25 公開日 2018-05-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis for MTR4-ZCCHC8 interactions that stimulate the MTR4 helicase in the nuclear exosome-targeting complex. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5Z58	Cryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom. 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... 著者 Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y. 登録日 2018-01-17 公開日 2018-09-19 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (4.9 Å) 主引用文献 Structure of the human activated spliceosome in three conformational states. Cell Res., 28, 2018
5Z56	cryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom. 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... 著者 Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y. 登録日 2018-01-17 公開日 2018-09-19 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (5.1 Å) 主引用文献 Structure of the human activated spliceosome in three conformational states. Cell Res., 28, 2018
5Z57	Cryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstrom 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ALANINE, BUD13 homolog, ... 著者 Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y. 登録日 2018-01-17 公開日 2018-09-19 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (6.5 Å) 主引用文献 Structure of the human activated spliceosome in three conformational states. Cell Res., 28, 2018
5Z3G	Cryo-EM structure of a nucleolar pre-60S ribosome (Rpf1-TAP) 分子名称: 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... 著者 Zhu, X, Zhou, D, Ye, K. 登録日 2018-01-06 公開日 2018-04-11 最終更新日 2019-11-06 実験手法 ELECTRON MICROSCOPY (3.65 Å) 主引用文献 Cryo-EM structure of an early precursor of large ribosomal subunit reveals a half-assembled intermediate. Protein Cell, 10, 2019
6FF7	human Bact spliceosome core structure 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, BUD13 homolog, ... 著者 Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H. 登録日 2018-01-03 公開日 2019-03-13 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Structure and Conformational Dynamics of the Human Spliceosomal BactComplex. Cell, 172, 2018
6C0F	Yeast nucleolar pre-60S ribosomal subunit (state 2) 分子名称: 5.8S rRNA, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ... 著者 Sanghai, Z.A, Miller, L, Barandun, J, Hunziker, M, Chaker-Margot, M, Klinge, S. 登録日 2017-12-29 公開日 2018-03-14 最終更新日 2020-01-08 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Modular assembly of the nucleolar pre-60S ribosomal subunit. Nature, 556, 2018
6FA9	CRYSTAL STRUCTURE OF THE DEAH-BOX HELICASE PRP2 分子名称: Putative mRNA splicing factor, SULFATE ION 著者 Schmitt, A, Hamann, F, Neumann, P, Ficner, R. 登録日 2017-12-15 公開日 2018-07-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of the spliceosomal DEAH-box ATPase Prp2. Acta Crystallogr D Struct Biol, 74, 2018
6FAC	CRYSTAL STRUCTURE OF THE DEAH-BOX HELICASE PRP2 IN COMPLEX WITH ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ... 著者 Schmitt, A, Hamann, F, Neumann, P, Ficner, R. 登録日 2017-12-15 公開日 2018-07-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystal structure of the spliceosomal DEAH-box ATPase Prp2. Acta Crystallogr D Struct Biol, 74, 2018
6FAA	CRYSTAL STRUCTURE OF THE DEAH-BOX HELICASE PRP2 IN COMPLEX WITH ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, ETHANOL, GLYCEROL, ... 著者 Schmitt, A, Hamann, F, Neumann, P, Ficner, R. 登録日 2017-12-15 公開日 2018-07-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Crystal structure of the spliceosomal DEAH-box ATPase Prp2. Acta Crystallogr D Struct Biol, 74, 2018
6FA5	CRYSTAL STRUCTURE OF THE DEAH-BOX HELICASE PRP2 IN COMPLEX WITH ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... 著者 Hamann, F, Schmitt, A, Neumann, P, Ficner, R. 登録日 2017-12-15 公開日 2018-07-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.303 Å) 主引用文献 Crystal structure of the spliceosomal DEAH-box ATPase Prp2. Acta Crystallogr D Struct Biol, 74, 2018
5YZG	The Cryo-EM Structure of Human Catalytic Step I Spliceosome (C complex) at 4.1 angstrom resolution 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Zhan, X, Yan, C, Zhang, X, Lei, J, Shi, Y. 登録日 2017-12-14 公開日 2018-08-08 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structure of a human catalytic step I spliceosome Science, 359, 2018
6BUA	Drosophila Dicer-2 apo homology model (helicase, Platform-PAZ, RNaseIII domains) 分子名称: Dicer-2, isoform A 著者 Shen, P.S, Sinha, N.K, Bass, B.L. 登録日 2017-12-09 公開日 2017-12-27 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (7.1 Å) 主引用文献 Dicer uses distinct modules for recognizing dsRNA termini. Science, 359, 2018
6BU9	Drosophila Dicer-2 bound to blunt dsRNA 分子名称: Dicer-2, isoform A, RNA (5'-R(*AP*CP*UP*AP*CP*UP*AP*UP*AP*CP*AP*AP*CP*CP*UP*AP*C)-3'), ... 著者 Shen, P.S, Sinha, N.K, Bass, B.L. 登録日 2017-12-09 公開日 2017-12-27 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (6.8 Å) 主引用文献 Dicer uses distinct modules for recognizing dsRNA termini. Science, 359, 2018
6F4A	Yeast mitochondrial RNA degradosome complex mtEXO 分子名称: Exoribonuclease II, mitochondrial, RNA (5'-R(P*AP*GP*AP*UP*AP*C)-3'), ... 著者 Razew, M, Nowak, E, Nowotny, M. 登録日 2017-11-29 公開日 2018-01-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.55 Å) 主引用文献 Structural analysis of mtEXO mitochondrial RNA degradosome reveals tight coupling of nuclease and helicase components. Nat Commun, 9, 2018
6EXN	Post-catalytic P complex spliceosome with 3' splice site docked 分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Intron lariat: UBC4 RNA, ... 著者 Wilkinson, M.E, Fica, S.M, Galej, W.P, Norman, C.M, Newman, A.J, Nagai, K. 登録日 2017-11-08 公開日 2018-01-17 最終更新日 2020-10-07 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Postcatalytic spliceosome structure reveals mechanism of 3'-splice site selection. Science, 358, 2017
6BK8	S. cerevisiae spliceosomal post-catalytic P complex 分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Lea1, ... 著者 Liu, S, Li, X, Zhou, Z.H, Zhao, R. 登録日 2017-11-07 公開日 2018-02-21 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structure of the yeast spliceosomal postcatalytic P complex. Science, 358, 2017
6EUD	Crystal structure of E. coli DExH-box NTPase HrpB 分子名称: 1,2-ETHANEDIOL, ATP-dependent RNA helicase HrpB 著者 Pietrzyk-Brzezinska, A.J, Wahl, M.C. 登録日 2017-10-30 公開日 2018-09-12 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of the Escherichia coli DExH-Box NTPase HrpB. Structure, 26, 2018
5YLZ	Cryo-EM Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae at 3.6 angstrom 分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... 著者 Wan, R, Yan, C, Bai, R, Lei, J, Shi, Y. 登録日 2017-10-20 公開日 2018-07-18 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae Cell, 171, 2017

<891011121314151617181920212223>