PDB: 4102 件ウェブページステータス検索Chemie searchBIRD

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7A1E	LppS with covalent adduct derived from 1c 分子名称: ACETATE ION, L,D-transpeptidase 2, phenylmethanethiol 著者 Schnell, R, Steiner, E.M. 登録日 2020-08-12 公開日 2021-04-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis. Cell Chem Biol, 28, 2021
7A11	LppS with covalent adduct derived from 1E 分子名称: ACETATE ION, L,D-transpeptidase 2, propane-1-thiol 著者 Schnell, R, Steiner, E.M. 登録日 2020-08-11 公開日 2021-04-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis. Cell Chem Biol, 28, 2021
7ABX	Perdeuterated E65Q-TIM complexed with 2-PHOSPHOGLYCOLIC ACID 分子名称: 2-PHOSPHOGLYCOLIC ACID, Triosephosphate isomerase 著者 Kelpsas, V, Caldararu, O, von Wachenfeldt, C, Oksanen, E. 登録日 2020-09-09 公開日 2021-07-28 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Neutron structures of Leishmania mexicana triosephosphate isomerase in complex with reaction-intermediate mimics shed light on the proton-shuttling steps. Iucrj, 8, 2021
1LY8	The crystal structure of a mutant enzyme of Coprinus cinereus peroxidase provides an understanding of its increased thermostability and insight into modelling of protein structures 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... 著者 Houborg, K, Harris, P, Poulsen, J.-C.N, Svendsen, A, Schneider, P, Larsen, S. 登録日 2002-06-07 公開日 2002-06-14 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 The structure of a mutant enzyme of Coprinus cinereus peroxidase provides an understanding of its increased thermostability. Acta Crystallogr.,Sect.D, 59, 2003
1M3Z	Biosynthetic thiolase, C89A mutant, complexed with acetyl coenzyme A 分子名称: ACETYL COENZYME *A, Acetyl-CoA acetyltransferase, SULFATE ION 著者 Kursula, P, Ojala, J, Lambeir, A.-M, Wierenga, R.K. 登録日 2002-07-03 公開日 2002-11-29 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 The catalytic cycle of biosynthetic thiolase: A conformational journey of an acetyl group through four binding modes and two oxyanion holes Biochemistry, 41, 2002
1M4S	Biosynthetic thiolase, Cys89 acetylated, unliganded form 分子名称: Acetyl-CoA acetyltransferase, GLYCEROL, SULFATE ION 著者 Kursula, P, Ojala, J, Lambeir, A.-M, Wierenga, R.K. 登録日 2002-07-03 公開日 2002-11-29 最終更新日 2018-03-07 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 The catalytic cycle of biosynthetic thiolase: A conformational journey of an acetyl group through four binding modes and two oxyanion holes Biochemistry, 41, 2002
1M61	Crystal structure of the apo SH2 domains of ZAP-70 分子名称: PHOSPHATE ION, TYROSINE-PROTEIN KINASE ZAP-70 著者 Folmer, R.H.A, Geschwindner, S, Xue, Y. 登録日 2002-07-11 公開日 2003-07-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure and NMR studies of the apo SH2 domains of ZAP-70: two bikes rather than a tandem Biochemistry, 41, 2002
1MLZ	Crystal Structure of 7,8-Diaminopelargonic Acid Synthase in complex with the trans-isomer of amiclenomycin. 分子名称: 7,8-diamino-pelargonic acid aminotransferase, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ... 著者 Sandmark, J, Mann, S, Marquet, A, Schneider, G. 登録日 2002-09-02 公開日 2002-12-04 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural basis for the inhibition of the biosynthesis of biotin by the antibiotic amiclenomycin J.Biol.Chem., 277, 2002
1M1O	Crystal structure of biosynthetic thiolase, C89A mutant, complexed with acetoacetyl-CoA 分子名称: ACETOACETYL-COENZYME A, Acetyl-CoA acetyltransferase, SULFATE ION 著者 Kursula, P, Ojala, J, Lambeir, A.-M, Wierenga, R.K. 登録日 2002-06-20 公開日 2002-11-29 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The catalytic cycle of biosynthetic thiolase: A conformational journey of an acetyl group through four binding modes and two oxyanion holes Biochemistry, 41, 2002
1M4T	Biosynthetic thiolase, Cys89 butyrylated 分子名称: Acetyl-CoA acetyltransferase, GLYCEROL, SULFATE ION 著者 Kursula, P, Ojala, J, Lambeir, A.-M, Wierenga, R.K. 登録日 2002-07-03 公開日 2002-11-29 最終更新日 2018-03-07 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 The catalytic cycle of biosynthetic thiolase: A conformational journey of an acetyl group through four binding modes and two oxyanion holes Biochemistry, 41, 2002
1M6Z	Crystal structure of reduced recombinant cytochrome c4 from Pseudomonas stutzeri 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cytochrome c4, GLYCEROL, ... 著者 Noergaard, A, Harris, P, Larsen, S, Christensen, H.E.M. 登録日 2002-07-18 公開日 2003-09-16 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structural comparison of recombinant Pseudomonas stutzeri cytochrome c4 in two oxidation states To be Published
8G3J	Non-ribosomal PCP-C didomain R2577G (thioether stabilised glycolic acid) acceptor bound state 分子名称: N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-{2-[(2-hydroxyethyl)sulfanyl]ethyl}-beta-alaninamide, PCP-C didomain 著者 Ho, Y.T.C, Izore, T, Cryle, M.J. 登録日 2023-02-08 公開日 2023-06-14 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Exploring the selectivity and engineering potential of an NRPS condensation domain involved in the biosynthesis of the thermophilic siderophore fuscachelin Front Catal, 3, 2023
8G3I	Non-ribosomal PCP-C didomain (thioether stabilised glycolic acid) acceptor bound state 分子名称: N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-{2-[(2-hydroxyethyl)sulfanyl]ethyl}-beta-alaninamide, PCP-C didomain 著者 Ho, Y.T.C, Izore, T, Cryle, M.J. 登録日 2023-02-08 公開日 2023-06-14 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.02 Å) 主引用文献 Exploring the selectivity and engineering potential of an NRPS condensation domain involved in the biosynthesis of the thermophilic siderophore fuscachelin Front Catal, 3, 2023
1M70	Crystal structure of oxidized recombinant cytochrome c4 from Pseudomonas stutzeri 分子名称: Cytochrome c4, GLYCEROL, HEME C 著者 Noergaard, A, Harris, P, Larsen, S, Christensen, H.E.M. 登録日 2002-07-18 公開日 2003-09-16 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Structural comparison of recombinant Pseudomonas stutzeri cytochrome c4 in two oxidation states To be Published
1MLY	Crystal Structure of 7,8-Diaminopelargonic Acid Synthase in complex with the cis isomer of amiclenomycin 分子名称: 7,8-diamino-pelargonic acid aminotransferase, CIS-AMICLENOMYCIN, PYRIDOXAL-5'-PHOSPHATE, ... 著者 Sandmark, J, Mann, S, Marquet, A, Schneider, G. 登録日 2002-09-02 公開日 2002-12-04 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Structural basis for the inhibition of the biosynthesis of biotin by the antibiotic amiclenomycin J.Biol.Chem., 277, 2002
8GHJ	Crystal structure of human AQP2 T125M mutant 分子名称: Aquaporin-2, CADMIUM ION 著者 Horsefield, S, Hagstroemer, C.J. 登録日 2023-03-10 公開日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 Structural and functional analysis of aquaporin-2 mutants involved in nephrogenic diabetes insipidus. Sci Rep, 13, 2023
8GJ4	A1 Tei: Adenylation domain 1 core construct from teicoplanin biosynthesis 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, MbtH-like short polypeptide, ... 著者 Hansen, M.H, Cryle, M.J. 登録日 2023-03-14 公開日 2023-12-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides. Nat Commun, 14, 2023
8GLC	A1 AncAla: Adenylation domain 1 core construct from ancestral reconstruction of glycopeptide antibiotic biosynthesis, alanine selection pocket 分子名称: MbtH-like short polypeptide, Non-ribosomal peptide synthetase 著者 Hansen, M.H, Cryle, M.J. 登録日 2023-03-21 公開日 2023-12-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.12 Å) 主引用文献 Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides. Nat Commun, 14, 2023
8GKM	A1 Leu graft + Leu: Adenylation domain 1 core construct from teicoplanin biosynthesis, leucine selection pocket graft; leucine bound 分子名称: ACETIC ACID, DI(HYDROXYETHYL)ETHER, LEUCINE, ... 著者 Hansen, M.H, Cryle, M.J. 登録日 2023-03-20 公開日 2023-12-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides. Nat Commun, 14, 2023
8GIC	A1 Tei + Hpg: Adenylation domain 1 core construct from teicoplanin biosynthesis; 4-hydroxyphenylglycine bound 分子名称: (2S)-AMINO(4-HYDROXYPHENYL)ACETIC ACID, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MbtH-like short polypeptide, ... 著者 Hansen, M.H, Cryle, M.J. 登録日 2023-03-14 公開日 2023-12-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides. Nat Commun, 14, 2023
8GJP	A1 Int graft: Adenylation domain 1 core construct from teicoplanin biosynthesis, intermediate selection pocket graft 分子名称: MbtH-like short polypeptide, Non-ribosomal peptide synthetase 著者 Hansen, M.H, Cryle, M.J. 登録日 2023-03-16 公開日 2023-12-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides. Nat Commun, 14, 2023
8HHU	Crystal structure of the SARS-CoV-2 main protease in complex with SY110 分子名称: (1~{R})-3,3-bis(fluoranyl)-~{N}-[(2~{R})-3-methoxy-1-oxidanylidene-1-[[(2~{R},3~{S})-3-oxidanyl-4-oxidanylidene-1-phenyl-4-(1,3-thiazol-2-ylmethylamino)butan-2-yl]amino]propan-2-yl]cyclohexane-1-carboxamide, 3C-like proteinase nsp5 著者 Zeng, R, Xie, L.W, Huang, C, Wang, K, Liu, Y.Z, Yang, S.Y, Lei, J. 登録日 2022-11-17 公開日 2023-03-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.258 Å) 主引用文献 A new generation M pro inhibitor with potent activity against SARS-CoV-2 Omicron variants. Signal Transduct Target Ther, 8, 2023
8FX6	Non-ribosomal PCP-C didomain (amide stabilised leucine) acceptor bound state 分子名称: N-[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl]-L-leucinamide, PCP-C didomain 著者 Ho, Y.T.C, Cryle, M.J. 登録日 2023-01-24 公開日 2023-06-21 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Not always an innocent bystander: the impact of stabilised phosphopantetheine moieties when studying nonribosomal peptide biosynthesis. Chem.Commun.(Camb.), 59, 2023
8FX7	Non-ribosomal PCP-C didomain (ester stabilised leucine) acceptor bound state 分子名称: 2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl L-leucinate, PCP-C didomain 著者 Ho, Y.T.C, Cryle, M.J. 登録日 2023-01-24 公開日 2023-06-21 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Not always an innocent bystander: the impact of stabilised phosphopantetheine moieties when studying nonribosomal peptide biosynthesis. Chem.Commun.(Camb.), 59, 2023
4EDS	Crystal structure of far-red fluorescent protein eqFP670 分子名称: far-red fluorescent protein eqFP650 著者 Pletnev, S, Pletnev, V.Z, Pletneva, N.V. 登録日 2012-03-27 公開日 2012-09-05 最終更新日 2013-03-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural basis for bathochromic shift of fluorescence in far-red fluorescent proteins eqFP650 and eqFP670. Acta Crystallogr.,Sect.D, 68, 2012

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