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7TZT
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BU of 7tzt by Molmil
Crystal structure of the E. coli thiM riboswitch in complex with N1,N1-dimethyl-N2-(quinoxalin-6-ylmethyl)ethane-1,2-diamine (linked compound 37)
分子名称: 6-methylquinoxaline, MAGNESIUM ION, MANGANESE (II) ION, ...
著者Nuthanakanti, A, Serganov, A.
登録日2022-02-16
公開日2022-05-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献SHAPE-enabled fragment-based ligand discovery for RNA.
Proc.Natl.Acad.Sci.USA, 119, 2022
7TZU
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BU of 7tzu by Molmil
Crystal structure of the E. coli thiM riboswitch bound to 1-(4-(piperazin-1-yl)pyridin-3-yl)-N-(quinoxalin-6-ylmethyl)methanamine (linked compound 38)
分子名称: 1-[4-(piperazin-1-yl)pyridin-3-yl]-N-[(quinoxalin-6-yl)methyl]methanamine, MAGNESIUM ION, MANGANESE (II) ION, ...
著者Nuthanakanti, A, Serganov, A.
登録日2022-02-16
公開日2022-05-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献SHAPE-enabled fragment-based ligand discovery for RNA.
Proc.Natl.Acad.Sci.USA, 119, 2022
6POM
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BU of 6pom by Molmil
Cryo-EM structure of the full-length Bacillus subtilis glyQS T-box riboswitch in complex with tRNA-Gly
分子名称: T-box GlyQS leader (155-MER), tRNAGly (75-MER)
著者Li, S, Su, Z, Zhang, J, Chiu, W.
登録日2019-07-04
公開日2019-11-20
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Structural basis of amino acid surveillance by higher-order tRNA-mRNA interactions.
Nat.Struct.Mol.Biol., 26, 2019
7E9I
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BU of 7e9i by Molmil
Crystal structure of a class I PreQ1 riboswitch aptamer (wild-type) complexed with a cognate ligand-derived photoaffinity probe
分子名称: 2-azanyl-5-[[2-(3-but-3-ynyl-1,2-diazirin-3-yl)ethylamino]methyl]-1,7-dihydropyrrolo[2,3-d]pyrimidin-4-one, 33-mer RNA, SULFATE ION
著者Numata, T, Schneekloth, J.S.
登録日2021-03-04
公開日2021-11-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A chemical probe based on the PreQ 1 metabolite enables transcriptome-wide mapping of binding sites.
Nat Commun, 12, 2021
7E9E
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Crystal structure of a class I PreQ1 riboswitch aptamer (ab13-14) complexed with a cognate ligand-derived photoaffinity probe
分子名称: 2-azanyl-5-[[2-(3-but-3-ynyl-1,2-diazirin-3-yl)ethylamino]methyl]-1,7-dihydropyrrolo[2,3-d]pyrimidin-4-one, 33-mer RNA, MAGNESIUM ION, ...
著者Numata, T, Schneekloth, J.S.
登録日2021-03-04
公開日2021-11-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献A chemical probe based on the PreQ 1 metabolite enables transcriptome-wide mapping of binding sites.
Nat Commun, 12, 2021
6XKN
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BU of 6xkn by Molmil
Class III PreQ1 riboswitch mutant A52G
分子名称: 7-DEAZA-7-AMINOMETHYL-GUANINE, Class III PreQ1 riboswitch
著者Srivastava, K.Y, Jenkins, J.L, Wedekind, J.E.
登録日2020-06-26
公開日2021-12-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献New insights into Class III PreQ1 metabolite binding
To Be Published
6XKO
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BU of 6xko by Molmil
Class III PreQ1 riboswitch mutant A84G
分子名称: 7-DEAZA-7-AMINOMETHYL-GUANINE, Class III PreQ1 riboswitch
著者Srivastava, K.Y, Jenkins, J.L, Wedekind, J.E.
登録日2020-06-26
公開日2021-12-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献New insights into Class III PreQ1 metabolite binding
To Be Published
7UQ6
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BU of 7uq6 by Molmil
tRNA T-box antiterminator fusion, construct #4
分子名称: BARIUM ION, POTASSIUM ION, RNA (86-MER)
著者Grigg, J.C, Price, I.R, Ke, A.
登録日2022-04-19
公開日2022-06-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.951 Å)
主引用文献tRNA Fusion to Streamline RNA Structure Determination: Case Studies in Probing Aminoacyl-tRNA Sensing Mechanisms by the T-Box Riboswitch
Crystals, 12, 2022
6CB3
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BU of 6cb3 by Molmil
Crystal structure of the L.Lactis YkoY riboswitch bound to cadmium
分子名称: BARIUM ION, CADMIUM ION, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Bachas, S, Ferre-D'amare, A.R.
登録日2018-02-01
公開日2018-06-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.891 Å)
主引用文献Convergent Use of Heptacoordination for Cation Selectivity by RNA and Protein Metalloregulators.
Cell Chem Biol, 25, 2018
6CC3
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BU of 6cc3 by Molmil
Crystal structure of ykoY-mntP riboswitch chimera bound to cadmium
分子名称: CADMIUM ION, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Bachas, S, Ferre-D'amare, A.R.
登録日2018-02-05
公開日2018-06-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.698 Å)
主引用文献Convergent Use of Heptacoordination for Cation Selectivity by RNA and Protein Metalloregulators.
Cell Chem Biol, 25, 2018
4TZW
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BU of 4tzw by Molmil
Co-crystals of the Ternary Complex Containing a T-box Stem I RNA, its Cognate tRNAGly, and B. subtilis YbxF protein, treated by removing lithium sulfate and replacing Mg2+ with Sr2+ post crystallization
分子名称: Ribosome-associated protein L7Ae-like, STRONTIUM ION, T-box Stem I, ...
著者Zhang, J, Ferre-D'Amare, A.R.
登録日2014-07-11
公開日2014-09-10
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (4.671 Å)
主引用文献Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration.
Structure, 22, 2014
4TZP
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BU of 4tzp by Molmil
As Grown, Untreated Co-crystals of the Ternary Complex Containing a T-box Stem I RNA, its cognate tRNAGly, and B. subtilis YbxF protein
分子名称: Ribosome-associated protein L7Ae-like, engineered tRNA, glyQ T-box Stem I
著者Zhang, J, Ferre-D'Amare, A.R.
登録日2014-07-10
公開日2014-09-10
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (8.503 Å)
主引用文献Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration.
Structure, 22, 2014
4TZV
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BU of 4tzv by Molmil
Co-crystals of the Ternary Complex Containing a T-box Stem I RNA, its Cognate tRNAGly, and B. subtilis YbxF protein, treated by removing lithium sulfate post crystallization
分子名称: Ribosome-associated protein L7Ae-like, T-box stem I, engineered tRNA
著者Zhang, J, Ferre-D'Amare, A.R.
登録日2014-07-11
公開日2014-09-10
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (5.03 Å)
主引用文献Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration.
Structure, 22, 2014
6WLU
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BU of 6wlu by Molmil
V. cholerae glycine riboswitch with glycine models, 5.7 Angstrom resolution
分子名称: RNA (231-MER)
著者Kappel, K, Zhang, K, Su, Z, Watkins, A.M, Kladwang, W, Li, S, Pintilie, G, Topkar, V.V, Rangan, R, Zheludev, I.N, Yesselman, J.D, Chiu, W, Das, R.
登録日2020-04-20
公開日2020-07-08
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (5.7 Å)
主引用文献Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures.
Nat.Methods, 17, 2020
6WLM
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BU of 6wlm by Molmil
F. nucleatum glycine riboswitch with glycine models, 7.4 Angstrom resolution
分子名称: RNA (171-MER)
著者Kappel, K, Zhang, K, Su, Z, Watkins, A.M, Kladwang, W, Li, S, Pintilie, G, Topkar, V.V, Rangan, R, Zheludev, I.N, Yesselman, J.D, Chiu, W, Das, R.
登録日2020-04-20
公開日2020-07-08
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (7.4 Å)
主引用文献Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures.
Nat.Methods, 17, 2020
6WLR
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BU of 6wlr by Molmil
SAM-IV riboswitch with SAM models, 4.8 Angstrom resolution
分子名称: RNA (119-MER)
著者Kappel, K, Zhang, K, Su, Z, Watkins, A.M, Kladwang, W, Li, S, Pintilie, G, Topkar, V.V, Rangan, R, Zheludev, I.N, Yesselman, J.D, Chiu, W, Das, R.
登録日2020-04-20
公開日2020-07-08
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures.
Nat.Methods, 17, 2020
6BFB
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BU of 6bfb by Molmil
Crystal structure of a F. nucleatum FMN riboswitch bound to WG-3
分子名称: 5-[(3S,4S)-3-(dimethylamino)-4-hydroxypyrrolidin-1-yl]-6-fluoro-4-methyl-8-oxo-3,4-dihydro-8H-1-thia-4,9b-diazacyclopenta[cd]phenalene-9-carboxylic acid, MAGNESIUM ION, RNA (54-MER), ...
著者Rizvi, N.F, Fischmann, T.O.
登録日2017-10-26
公開日2018-02-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Discovery of Selective RNA-Binding Small Molecules by Affinity-Selection Mass Spectrometry.
ACS Chem. Biol., 13, 2018
6CC1
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BU of 6cc1 by Molmil
Crystal structure of ykoY-alx riboswitch chimera bound to cadmium
分子名称: BARIUM ION, CADMIUM ION, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Bachas, S.T, Ferre-D'amare, A.R.
登録日2018-02-05
公開日2018-06-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Convergent Use of Heptacoordination for Cation Selectivity by RNA and Protein Metalloregulators.
Cell Chem Biol, 25, 2018
6WLL
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BU of 6wll by Molmil
Apo F. nucleatum glycine riboswitch models, 10.0 Angstrom resolution
分子名称: RNA (171-MER)
著者Kappel, K, Zhang, K, Su, Z, Watkins, A.M, Kladwang, W, Li, S, Pintilie, G, Topkar, V.V, Rangan, R, Zheludev, I.N, Yesselman, J.D, Chiu, W, Das, R.
登録日2020-04-20
公開日2020-07-08
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (10 Å)
主引用文献Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures.
Nat.Methods, 17, 2020
6WLT
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BU of 6wlt by Molmil
Apo V. cholerae glycine riboswitch models, 4.8 Angstrom resolution
分子名称: RNA (231-MER)
著者Kappel, K, Zhang, K, Su, Z, Watkins, A.M, Kladwang, W, Li, S, Pintilie, G, Topkar, V.V, Rangan, R, Zheludev, I.N, Yesselman, J.D, Chiu, W, Das, R.
登録日2020-04-20
公開日2020-07-08
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures.
Nat.Methods, 17, 2020
6WLQ
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BU of 6wlq by Molmil
Apo SAM-IV riboswitch models, 4.7 Angstrom resolution
分子名称: RNA (119-MER)
著者Kappel, K, Zhang, K, Su, Z, Watkins, A.M, Kladwang, W, Li, S, Pintilie, G, Topkar, V.V, Rangan, R, Zheludev, I.N, Yesselman, J.D, Chiu, W, Das, R.
登録日2020-04-20
公開日2020-07-08
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures.
Nat.Methods, 17, 2020
7UZ0
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BU of 7uz0 by Molmil
AntiT-tRNA flip UCCA
分子名称: AntiT-tRNA flip UCCA, MAGNESIUM ION, STRONTIUM ION
著者Price, I.R, Grigg, J.C, Ke, A.
登録日2022-05-07
公開日2022-06-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献tRNA Fusion to Streamline RNA Structure Determination: Case Studies in Probing Aminoacyl-tRNA Sensing Mechanisms by the T-Box Riboswitch
Crystals, 12, 2022
6UFM
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BU of 6ufm by Molmil
Cocrystal Structure of the Nocardia farcinica ileS T-box riboswitch in complex with its cognate tRNA
分子名称: RNA (77-MER), RNA (98-MER), SULFATE ION
著者Suddala, K.C, Zhang, J.
登録日2019-09-24
公開日2019-12-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献High-affinity recognition of specific tRNAs by an mRNA anticodon-binding groove.
Nat.Struct.Mol.Biol., 26, 2019
4MGM
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BU of 4mgm by Molmil
Crystal structure of the in vitro transcribed G. kaustophilus tRNA-Gly
分子名称: MAGNESIUM ION, tRNA glycine
著者Grigg, J.C, Ke, A.
登録日2013-08-28
公開日2013-10-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural Determinants for Geometry and Information Decoding of tRNA by T Box Leader RNA.
Structure, 21, 2013
5UZA
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BU of 5uza by Molmil
Adenine riboswitch aptamer domain labelled with iodo-uridine by position-selective labelling of RNA (PLOR)
分子名称: ADENINE, MAGNESIUM ION, RNA (71-MER)
著者Liu, Y, Stagno, J.R, Wang, Y.-X.
登録日2017-02-25
公開日2018-02-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Incorporation of isotopic, fluorescent, and heavy-atom-modified nucleotides into RNAs by position-selective labeling of RNA.
Nat Protoc, 13, 2018

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件を2024-06-12に公開中

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