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5OBN
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BU of 5obn by Molmil
NMR solution structure of U11/U12 65K protein's C-terminal RRM domain (381-516)
分子名称: RNA-binding protein 40
著者Norppa, A.J, Kauppala, T.M, Heikkinen, H.A, Verma, B, Iwai, H, Frilander, M.J.
登録日2017-06-28
公開日2018-01-24
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Mutations in the U11/U12-65K protein associated with isolated growth hormone deficiency lead to structural destabilization and impaired binding of U12 snRNA.
RNA, 24, 2018
1DRZ
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BU of 1drz by Molmil
U1A SPLICEOSOMAL PROTEIN/HEPATITIS DELTA VIRUS GENOMIC RIBOZYME COMPLEX
分子名称: MAGNESIUM ION, PROTEIN (U1 SMALL RIBONUCLEOPROTEIN A), RNA (HEPATITIS DELTA VIRUS GENOMIC RIBOZYME), ...
著者Ferre-D'Amare, A.R, Zhou, K, Doudna, J.A.
登録日1998-09-01
公開日1999-02-16
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a hepatitis delta virus ribozyme.
Nature, 395, 1998
3LRV
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BU of 3lrv by Molmil
The Prp19 WD40 Domain Contains a Conserved Protein Interaction Region Essential for its Function.
分子名称: Pre-mRNA-splicing factor 19, SULFATE ION
著者Vander Kooi, C.W, Chazin, W.J.
登録日2010-02-11
公開日2010-05-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Prp19 WD40 domain contains a conserved protein interaction region essential for its function.
Structure, 18, 2010
2IFE
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BU of 2ife by Molmil
TRANSLATION INITIATION FACTOR IF3 FROM ESCHERICHIA COLI RIBOSOME BINDING DOMAIN (RESIDUES 84-180)
分子名称: PROTEIN (TRANSLATION INITIATION FACTOR IF3)
著者De Cock, E, Garcia, C, Dardel, F.
登録日1998-12-16
公開日1998-12-23
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Interaction of E. Coli Translation Initiation Factor If3 with the Ribosome
To be Published
1AUD
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BU of 1aud by Molmil
U1A-UTRRNA, NMR, 31 STRUCTURES
分子名称: RNA 3UTR, U1A 102
著者Allain, F.H.-T, Gubser, C.C, Howe, P.W.A, Nagai, K, Neuhaus, D, Varani, G.
登録日1997-08-22
公開日1998-02-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural basis of the RNA-binding specificity of human U1A protein.
EMBO J., 16, 1997
6T3N
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BU of 6t3n by Molmil
Structure of Oceanobacillus iheyensis group II intron G-mutant (C289G/C358G/G385C) in the presence of Na+, Mg2+ and 5'-exon
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Group IIC Intron Ribozyme, MAGNESIUM ION, ...
著者Marcia, M, Pyle, A.M.
登録日2019-10-11
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献Visualizing group II intron dynamics between the first and second steps of splicing.
Nat Commun, 11, 2020
6T3R
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BU of 6t3r by Molmil
Structure of Oceanobacillus iheyensis group II intron U-mutant (C289U/C358U/G385A) in the presence of K+, Mg2+ and 5'-exon
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Group IIC Intron Ribozyme, MAGNESIUM ION, ...
著者Marcia, M, Pyle, A.M.
登録日2019-10-11
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.57 Å)
主引用文献Visualizing group II intron dynamics between the first and second steps of splicing.
Nat Commun, 11, 2020
6T3K
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BU of 6t3k by Molmil
Structure of Oceanobacillus iheyensis group II intron G-mutant (C289G/C358G/G385C) in the presence of K+, Mg2+ and 5'-exon
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Group IIC Intron Ribozyme, MAGNESIUM ION, ...
著者Marcia, M, Pyle, A.M.
登録日2019-10-11
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.44 Å)
主引用文献Visualizing group II intron dynamics between the first and second steps of splicing.
Nat Commun, 11, 2020
4FAW
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BU of 4faw by Molmil
Structure of Oceanobacillus iheyensis group II intron in the presence of K+, Mg2+ and a hydrolyzed oligonucleotide fragment
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-R(*A*UP*UP*UP*AP*UP*UP*A)-3', Group IIC intron, ...
著者Marcia, M, Pyle, A.M.
登録日2012-05-22
公開日2012-11-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Visualizing Group II Intron Catalysis through the Stages of Splicing.
Cell(Cambridge,Mass.), 151, 2012
4FB0
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BU of 4fb0 by Molmil
Structure of Oceanobacillus iheyensis group II intron C377G mutant in a ligand-free state in the presence of K+ and Mg2+
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Group IIC intron, MAGNESIUM ION, ...
著者Marcia, M, Pyle, A.M.
登録日2012-05-22
公開日2012-11-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献Visualizing Group II Intron Catalysis through the Stages of Splicing.
Cell(Cambridge,Mass.), 151, 2012
4FAR
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BU of 4far by Molmil
Structure of Oceanobacillus iheyensis group II intron in the presence of K+, Mg2+ and 5'-exon
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Group IIC intron, MAGNESIUM ION, ...
著者Marcia, M, Pyle, A.M.
登録日2012-05-22
公開日2012-11-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Visualizing Group II Intron Catalysis through the Stages of Splicing.
Cell(Cambridge,Mass.), 151, 2012
4FAQ
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BU of 4faq by Molmil
Structure of Oceanobacillus iheyensis group II intron in the presence of K+, Ca2+ and 5'-exon
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, Group IIC intron, ...
著者Marcia, M, Pyle, A.M.
登録日2012-05-22
公開日2012-11-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Visualizing Group II Intron Catalysis through the Stages of Splicing.
Cell(Cambridge,Mass.), 151, 2012
4FAX
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BU of 4fax by Molmil
Structure of Oceanobacillus iheyensis group II intron in a ligand-free state in the presence of Na+ and Mg2+
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Group IIC intron, MAGNESIUM ION, ...
著者Marcia, M, Pyle, A.M.
登録日2012-05-22
公開日2012-11-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Visualizing Group II Intron Catalysis through the Stages of Splicing.
Cell(Cambridge,Mass.), 151, 2012
4FAU
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BU of 4fau by Molmil
Structure of Oceanobacillus iheyensis group II intron in the presence of Li+, Mg2+ and 5'-exon
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Group IIC intron, MAGNESIUM ION, ...
著者Marcia, M, Pyle, A.M.
登録日2012-05-22
公開日2012-11-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献Visualizing Group II Intron Catalysis through the Stages of Splicing.
Cell(Cambridge,Mass.), 151, 2012
4DGW
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BU of 4dgw by Molmil
Crystal Structure of the SF3a splicing factor complex of U2 snRNP
分子名称: Pre-mRNA-splicing factor PRP11, Pre-mRNA-splicing factor PRP21, Pre-mRNA-splicing factor PRP9, ...
著者Lin, P.C.
登録日2012-01-26
公開日2012-05-02
最終更新日2018-07-25
実験手法X-RAY DIFFRACTION (3.112 Å)
主引用文献Structure and assembly of the SF3a splicing factor complex of U2 snRNP
Embo J., 31, 2012
5SU5
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BU of 5su5 by Molmil
PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment P03E05 from the F2X-Universal Library
分子名称: 5-bromo-1-methylpyrimidine-2,4(1H,3H)-dione, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8
著者Barthel, T, Wollenhaupt, J, Lima, G.M.A, Wahl, M.C, Weiss, M.S.
登録日2022-08-26
公開日2022-11-02
最終更新日2022-11-30
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Large-Scale Crystallographic Fragment Screening Expedites Compound Optimization and Identifies Putative Protein-Protein Interaction Sites.
J.Med.Chem., 65, 2022
5STN
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BU of 5stn by Molmil
PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment P03A11 from the F2X-Universal Library
分子名称: A1 cistron-splicing factor AAR2, N-methyl-1-{(1S,2R)-2-[(1,2,4-triazolidin-1-yl)methyl]cyclohexyl}methanamine, Pre-mRNA-splicing factor 8
著者Barthel, T, Wollenhaupt, J, Lima, G.M.A, Wahl, M.C, Weiss, M.S.
登録日2022-08-26
公開日2022-11-02
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Large-Scale Crystallographic Fragment Screening Expedites Compound Optimization and Identifies Putative Protein-Protein Interaction Sites.
J.Med.Chem., 65, 2022
5SU9
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BU of 5su9 by Molmil
PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment P03F06 from the F2X-Universal Library
分子名称: A1 cistron-splicing factor AAR2, N~2~-methyl-N~2~-[2-methyl-2-(4-methylphenyl)propyl]glycinamide, Pre-mRNA-splicing factor 8
著者Barthel, T, Wollenhaupt, J, Lima, G.M.A, Wahl, M.C, Weiss, M.S.
登録日2022-08-26
公開日2022-11-02
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Large-Scale Crystallographic Fragment Screening Expedites Compound Optimization and Identifies Putative Protein-Protein Interaction Sites.
J.Med.Chem., 65, 2022
5SUF
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BU of 5suf by Molmil
PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment P03H03 from the F2X-Universal Library
分子名称: 1-benzyl-1H-pyrazole-4-carboxylic acid, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ...
著者Barthel, T, Wollenhaupt, J, Lima, G.M.A, Wahl, M.C, Weiss, M.S.
登録日2022-08-26
公開日2022-11-02
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Large-Scale Crystallographic Fragment Screening Expedites Compound Optimization and Identifies Putative Protein-Protein Interaction Sites.
J.Med.Chem., 65, 2022
5SUC
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BU of 5suc by Molmil
PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment P03G02 from the F2X-Universal Library
分子名称: A1 cistron-splicing factor AAR2, N-(2-hydroxyethyl)-N-methyl-2-phenylacetamide, Pre-mRNA-splicing factor 8
著者Barthel, T, Wollenhaupt, J, Lima, G.M.A, Wahl, M.C, Weiss, M.S.
登録日2022-08-26
公開日2022-11-02
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Large-Scale Crystallographic Fragment Screening Expedites Compound Optimization and Identifies Putative Protein-Protein Interaction Sites.
J.Med.Chem., 65, 2022
5STB
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BU of 5stb by Molmil
PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment P02F05 from the F2X-Universal Library
分子名称: 3-ethyl-5-(ethylsulfanyl)-4H-1,2,4-triazol-4-amine, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8
著者Barthel, T, Wollenhaupt, J, Lima, G.M.A, Wahl, M.C, Weiss, M.S.
登録日2022-08-26
公開日2022-11-02
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Large-Scale Crystallographic Fragment Screening Expedites Compound Optimization and Identifies Putative Protein-Protein Interaction Sites.
J.Med.Chem., 65, 2022
5ST3
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BU of 5st3 by Molmil
PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment P02C09 from the F2X-Universal Library
分子名称: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, oxane-4-carboxamide
著者Barthel, T, Wollenhaupt, J, Lima, G.M.A, Wahl, M.C, Weiss, M.S.
登録日2022-08-26
公開日2022-11-02
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Large-Scale Crystallographic Fragment Screening Expedites Compound Optimization and Identifies Putative Protein-Protein Interaction Sites.
J.Med.Chem., 65, 2022
5ST5
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BU of 5st5 by Molmil
PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment P02D06 from the F2X-Universal Library
分子名称: (3S)-3-amino-3-(3-chlorophenyl)propan-1-ol, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8
著者Barthel, T, Wollenhaupt, J, Lima, G.M.A, Wahl, M.C, Weiss, M.S.
登録日2022-08-26
公開日2022-11-02
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Large-Scale Crystallographic Fragment Screening Expedites Compound Optimization and Identifies Putative Protein-Protein Interaction Sites.
J.Med.Chem., 65, 2022
5STT
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BU of 5stt by Molmil
PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment P03C03 from the F2X-Universal Library
分子名称: 2-(2-methoxyethoxy)benzoic acid, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8
著者Barthel, T, Wollenhaupt, J, Lima, G.M.A, Wahl, M.C, Weiss, M.S.
登録日2022-08-26
公開日2022-11-02
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Large-Scale Crystallographic Fragment Screening Expedites Compound Optimization and Identifies Putative Protein-Protein Interaction Sites.
J.Med.Chem., 65, 2022
5ST1
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BU of 5st1 by Molmil
PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment P02C03 from the F2X-Universal Library
分子名称: 5-methoxy-2-nitrosophenol, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8
著者Barthel, T, Wollenhaupt, J, Lima, G.M.A, Wahl, M.C, Weiss, M.S.
登録日2022-08-26
公開日2022-11-02
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Large-Scale Crystallographic Fragment Screening Expedites Compound Optimization and Identifies Putative Protein-Protein Interaction Sites.
J.Med.Chem., 65, 2022

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