PDB: 221051 件ウェブページステータス検索Chemie searchBIRD

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6DXS	Crystal structure of the LigJ hydratase E284Q mutant substrate complex with (3Z)-2-keto-4-carboxy-3-hexenedioate 分子名称: (2Z)-4-oxobut-2-ene-1,2,4-tricarboxylic acid, 4-oxalomesaconate hydratase, ZINC ION 著者 Mabanglo, M.F, Raushel, F.M, Hogancamp, T.N. 登録日 2018-06-29 公開日 2018-09-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure and Reaction Mechanism of the LigJ Hydratase: An Enzyme Critical for the Bacterial Degradation of Lignin in the Protocatechuate 4,5-Cleavage Pathway. Biochemistry, 57, 2018
8EJX	Crystal structure of human cyclophilin D (CypD) with in complex with the covalently bound Ebselen inhibitor 分子名称: N-phenyl-2-selanylbenzamide, Peptidyl-prolyl cis-trans isomerase F, mitochondrial 著者 Lovell, S, Battaile, K.P, Yan, S. 登録日 2022-09-19 公開日 2023-10-18 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 New cyclophilin D inhibitor rescues mitochondrial and cognitive function in Alzheimer's disease. Brain, 147, 2024
4YEA	Crystal structure of cisplatin bound to a human copper chaperone (dimer) - new refinement 分子名称: COPPER (II) ION, Copper transport protein ATOX1, SULFATE ION 著者 Shabalin, I.G, Dauter, Z, Jaskolski, M, Minor, W, Wlodawer, A. 登録日 2015-02-23 公開日 2015-03-18 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Crystallography and chemistry should always go together: a cautionary tale of protein complexes with cisplatin and carboplatin. Acta Crystallogr.,Sect.D, 71, 2015
5JPM	Structure of the complex of human complement C4 with MASP-2 rebuilt using iMDFF 分子名称: Complement C4-A, Mannan-binding lectin serine protease 2, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Croll, T.I, Andersen, G.R. 登録日 2016-05-03 公開日 2016-08-10 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.75 Å) 主引用文献 Re-evaluation of low-resolution crystal structures via interactive molecular-dynamics flexible fitting (iMDFF): a case study in complement C4. Acta Crystallogr D Struct Biol, 72, 2016
6Y9S	Crystal structure of GSK-3b in complex with the imidazo[1,5-a]pyridine-3-carboxamide inhibitor 16 分子名称: ACETATE ION, Glycogen synthase kinase-3 beta, ~{N}-(oxan-4-ylmethyl)-6-(5-propan-2-yloxypyridin-3-yl)imidazo[1,5-a]pyridine-3-carboxamide 著者 Krapp, S, Griessner, A, Blaesse, M, Buonfiglio, R, Ombrato, R. 登録日 2020-03-10 公開日 2020-05-20 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Discovery of Novel Imidazopyridine GSK-3 beta Inhibitors Supported by Computational Approaches. Molecules, 25, 2020
6Y9R	Crystal structure of GSK-3b in complex with the 1H-indazole-3-carboxamide inhibitor 2 分子名称: ACETATE ION, GLYCEROL, Glycogen synthase kinase-3 beta, ... 著者 Krapp, S, Griessner, A, Blaesse, M, Buonfiglio, R, Ombrato, R. 登録日 2020-03-10 公開日 2020-05-20 最終更新日 2020-07-08 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Discovery of Novel Imidazopyridine GSK-3 beta Inhibitors Supported by Computational Approaches. Molecules, 25, 2020
4YDX	Crystal structure of cisplatin bound to a human copper chaperone (monomer) - new refinement 分子名称: 3,3',3''-phosphanetriyltripropanoic acid, Copper transport protein ATOX1, PLATINUM (II) ION, ... 著者 Shabalin, I.G, Boal, A.K, Dauter, Z, Jaskolski, M, Minor, W, Rosenzweig, A.C, Wlodawer, A. 登録日 2015-02-23 公開日 2015-03-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.602 Å) 主引用文献 Crystallography and chemistry should always go together: a cautionary tale of protein complexes with cisplatin and carboplatin. Acta Crystallogr.,Sect.D, 71, 2015
6ZFW	X-ray structure of the soluble N-terminal domain of T. cruzi PEX-14 分子名称: ACETATE ION, BETA-MERCAPTOETHANOL, GLYCEROL, ... 著者 Softley, C.A, Ostertag, M.O, Sattler, M, Popowicz, G.P. 登録日 2020-06-18 公開日 2020-12-09 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Deep learning model predicts water interaction sites on the surface of proteins using limited-resolution data. Chem.Commun.(Camb.), 56, 2020
6ZK0	1.47A human IMPase with ebselen 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Inositol monophosphatase 1, ... 著者 Bax, B.D, Fenn, G.D. 登録日 2020-06-29 公開日 2020-09-23 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Crystallization and structure of ebselen bound to Cys141 of human inositol monophosphatase. Acta Crystallogr.,Sect.F, 76, 2020
5LIT	Structure of the DNA duplex d(AAATTT)2 with the potential antiparasitic drug 6XV at 1.25 A resolution 分子名称: 4-((4,5-dihydro-1H-imidazol-2-yl)amino)-N-(4-((4,5-dihydro-1H-imidazol-2-yl)amino)phenyl)benzamide dihydrochloride, DNA (5'-D(*AP*AP*AP*TP*TP*T)-3'), MAGNESIUM ION 著者 Millan, C.R, Dardonville, C, de Koning, H.P, Saperas, N, Lourdes Campos, J. 登録日 2016-07-15 公開日 2017-06-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Functional and structural analysis of AT-specific minor groove binders that disrupt DNA-protein interactions and cause disintegration of the Trypanosoma brucei kinetoplast. Nucleic Acids Res., 45, 2017
8HIT	Crystal structure of anti-CTLA-4 humanized IgG1 MAb--JS007 in complex with human CTLA-4 分子名称: Cytotoxic T-lymphocyte protein 4, JS007-VH, JS007-VL 著者 Tan, S, Shi, Y, Wang, Q, Gao, G.F, Guan, J, Chai, Y, Qi, J. 登録日 2022-11-21 公開日 2023-02-01 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Characterization of the high-affinity anti-CTLA-4 monoclonal antibody JS007 for immune checkpoint therapy of cancer. Mabs, 15, 2023
8H3W	Crystal structure of chicken egg lysozyme at ambient temperature 分子名称: Lysozyme C 著者 DeMirci, H. 登録日 2022-10-09 公開日 2023-03-22 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Rapid and efficient ambient temperature X-ray crystal structure determination at Turkish Light Source. Sci Rep, 13, 2023
7YGG	Crystal structure of human CD47 in complex with engineered SIRPa.D1(N80A) 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Leukocyte surface antigen CD47, ... 著者 Yu, J, Tian, W. 登録日 2022-07-11 公開日 2022-10-19 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Crystal Structure of Human CD47 in Complex with Engineered SIRP alpha.D1(N80A). Molecules, 27, 2022
7PH1	Trypsin in complex with BPTI mutant (2S)-2-amino-4-monofluorobutanoic acid 分子名称: CALCIUM ION, Cationic trypsin, GLYCEROL, ... 著者 Dimos, N, Leppkes, J, Koksch, B, Loll, B. 登録日 2021-08-16 公開日 2022-03-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.18 Å) 主引用文献 Water Network in the Binding Pocket of Fluorinated BPTI-Trypsin Complexes─Insights from Simulation and Experiment. J.Phys.Chem.B, 126, 2022
6EGC	Single-chain version of 2L4HC2_23 (PDB 5J0K) 分子名称: SC_2L4HC2_23 著者 Bick, M.J, Chen, Z, DiMaio, F. 登録日 2018-08-19 公開日 2019-05-29 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Self-Assembling 2D Arrays with de Novo Protein Building Blocks. J.Am.Chem.Soc., 141, 2019
5YGP	Human TNFRSF25 death domain mutant-D412E 分子名称: SULFATE ION, TNFRSF25 death domain, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Yin, X, Jin, T.C. 登録日 2017-09-25 公開日 2018-10-03 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Crystal structure and activation mechanism of DR3 death domain. Febs J., 286, 2019
7M2T	Crystallographic Structure of the Monoclinic Form of Satellite Tobacco Mosaic Virus 分子名称: Coat protein, MAGNESIUM ION, PHOSPHATE ION, ... 著者 McPherson, A. 登録日 2021-03-17 公開日 2021-12-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Structures of additional crystal forms of Satellite tobacco mosaic virus grown from a variety of salts. Acta Crystallogr.,Sect.F, 77, 2021
8TXS	Solution NMR structure of designed peptide BH26 (RGVTVPHNGESKDYSV) 分子名称: BH26 peptide 著者 McShan, A.C, Torres, M.P. 登録日 2023-08-24 公開日 2023-09-06 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Generative beta-hairpin design using a residue-based physicochemical property landscape. Biophys.J., 2024
1GK7	HUMAN VIMENTIN COIL 1A FRAGMENT (1A) 分子名称: SULFATE ION, VIMENTIN 著者 Strelkov, S.V, Herrmann, H, Geisler, N, Zimbelmann, R, Aebi, U, Burkhard, P. 登録日 2001-08-08 公開日 2002-03-15 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Conserved Segments 1A and 2B of the Intermediate Filament Dimer: Their Atomic Structures and Role in Filament Assembly. Embo J., 21, 2002
5YGS	Human TNFRSF25 death domain 分子名称: Human TNRSF25 death domain, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Yin, X, Jin, T. 登録日 2017-09-26 公開日 2018-10-03 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.691 Å) 主引用文献 Crystal structure and activation mechanism of DR3 death domain. Febs J., 286, 2019
7RHO	Human IgG1 Fc fragment, hinge-free, expressed in E. coli 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Fc fragment of human IgG1 著者 Gallagher, D.T. 登録日 2021-07-18 公開日 2022-11-09 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Effects of glycans and hinge on dynamics in the IgG1 Fc. J.Biomol.Struct.Dyn., 2023
6GKF	Structure of 14-3-3 gamma in complex with caspase-2 14-3-3 binding motif Ser139 分子名称: 14-3-3 protein gamma, Caspase-2 著者 Alblova, M, Obsil, T, Obsilova, V. 登録日 2018-05-20 公開日 2018-10-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.598 Å) 主引用文献 14-3-3 protein masks the nuclear localization sequence of caspase-2. FEBS J., 285, 2018
5Z0A	ST0452(Y97N)-GlcNAc binding form 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Dual sugar-1-phosphate nucleotidylyltransferase 著者 Honda, Y, Nakano, S, Ito, S, Dadashipour, M, Zhang, Z, Kawarabayasi, Y. 登録日 2017-12-19 公開日 2018-10-31 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Improvement of ST0452N-Acetylglucosamine-1-Phosphate Uridyltransferase Activity by the Cooperative Effect of Two Single Mutations Identified through Structure-Based Protein Engineering Appl. Environ. Microbiol., 84, 2018
6ZMM	Crystal structure of human NDRG1 分子名称: CHLORIDE ION, Protein NDRG1 著者 Mustonen, V, Kursula, P, Ruskamo, S. 登録日 2020-07-03 公開日 2020-12-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.96 Å) 主引用文献 Crystal and solution structure of NDRG1, a membrane-binding protein linked to myelination and tumour suppression. Febs J., 288, 2021
1GTK	Time-resolved and static-ensemble structural chemistry of hydroxymethylbilane synthase 分子名称: 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, PORPHOBILINOGEN DEAMINASE 著者 Helliwell, J.R, Nieh, Y.P, Raftery, J, Cassetta, A, Habash, J, Carr, P.D, Ursby, T, Wulff, M, Thompson, A.W, Niemann, A.C, Haedener, A. 登録日 2002-01-16 公開日 2003-01-16 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Time-Resolved and Static-Ensemble Structural Chemistry of Hydroxymethylbilane Synthase Faraday Discuss., 122, 2003

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