6PPR
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![BU of 6ppr by Molmil](/molmil-images/mine/6ppr) | Cryo-EM structure of AdnA(D934A)-AdnB(D1014A) in complex with AMPPNP and DNA | 分子名称: | ATP-dependent DNA helicase (UvrD/REP), DNA (70-MER), IRON/SULFUR CLUSTER, ... | 著者 | Jia, N, Unciuleac, M, Shuman, S, Patel, D.J. | 登録日 | 2019-07-08 | 公開日 | 2019-11-20 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structures and single-molecule analysis of bacterial motor nuclease AdnAB illuminate the mechanism of DNA double-strand break resection. Proc.Natl.Acad.Sci.USA, 116, 2019
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2DY4
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![BU of 2dy4 by Molmil](/molmil-images/mine/2dy4) | Crystal structure of RB69 GP43 in complex with DNA containing Thymine Glycol | 分子名称: | 5'-D(*CP*GP*(CTG)P*GP*GP*AP*AP*TP*GP*A*CP*AP*GP*CP*CP*GP*CP*G)-3', 5'-D(*GP*CP*GP*GP*CP*TP*GP*T*CP*AP*TP*TP*CP*CP*A)-3', DNA polymerase | 著者 | Aller, P, Rould, M.A, Hogg, M, Wallace, S.S, Doublie, S. | 登録日 | 2006-09-06 | 公開日 | 2007-01-09 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | A structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol. Proc.Natl.Acad.Sci.USA, 104, 2007
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2W7P
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![BU of 2w7p by Molmil](/molmil-images/mine/2w7p) | Structure and Activity of Bypass Synthesis by Human DNA Polymerase Kappa Opposite the 7,8-Dihydro-8-oxodeoxyguanosine Adduct | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*C)-3', 5'-D(TP*CP*AP*CP*8OGP*GP*AP*AP*TP*CP*CP*TP* TP*CP*CP*CP*CP*C)-3', ... | 著者 | Irimia, A, Egli, M. | 登録日 | 2008-12-23 | 公開日 | 2009-06-16 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.71 Å) | 主引用文献 | Structural and Functional Elucidation of the Mechanism Promoting Error-Prone Synthesis by Human DNA Polymerase Kappa Opposite the 7,8-Dihydro-8-Oxo-2'-Deoxyguanosine Adduct. J.Biol.Chem., 284, 2009
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4E3S
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![BU of 4e3s by Molmil](/molmil-images/mine/4e3s) | RB69 DNA Polymerase Ternary Complex with dQTP Opposite dT | 分子名称: | 3-{2-deoxy-5-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-erythro-pentofuranosyl}-7-methyl-3H-imidazo[4,5-b]pyridine, CALCIUM ION, DNA polymerase, ... | 著者 | Xia, S, Wang, J, Konigsberg, W.H. | 登録日 | 2012-03-10 | 公開日 | 2012-05-23 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Probing minor groove hydrogen bonding interactions between RB69 DNA polymerase and DNA. Biochemistry, 51, 2012
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4DTX
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![BU of 4dtx by Molmil](/molmil-images/mine/4dtx) | RB69 DNA Polymerase Ternary Complex with dTTP Opposite an Abasic Site and ddC/dG as the Penultimate Base-pair | 分子名称: | CALCIUM ION, DNA polymerase, DNA primer, ... | 著者 | Xia, S, Wang, J, Konigsberg, W.H. | 登録日 | 2012-02-21 | 公開日 | 2012-06-06 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
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2W7O
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![BU of 2w7o by Molmil](/molmil-images/mine/2w7o) | Structure and Activity of Bypass Synthesis by Human DNA Polymerase Kappa Opposite the 7,8-Dihydro-8-oxodeoxyguanosine Adduct | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*C)-3', 5'-D(TP*CP*AP*CP*8OGP*GP*AP*AP*TP*CP*CP*TP* TP*CP*CP*CP*CP*C)-3', ... | 著者 | Irimia, A, Egli, M. | 登録日 | 2008-12-23 | 公開日 | 2009-06-16 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.16 Å) | 主引用文献 | Structural and Functional Elucidation of the Mechanism Promoting Error-Prone Synthesis by Human DNA Polymerase Kappa Opposite the 7,8-Dihydro-8-Oxo-2'-Deoxyguanosine Adduct. J.Biol.Chem., 284, 2009
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5NPK
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![BU of 5npk by Molmil](/molmil-images/mine/5npk) | 1.98A STRUCTURE OF THIOPHENE1 WITH S.AUREUS DNA GYRASE AND DNA | 分子名称: | CHLORIDE ION, DNA (5'-D(*AP*GP*CP*CP*GP*TP*AP*GP*GP*TP*AP*CP*CP*TP*AP*CP*GP*GP*CP*T)-3'), DNA gyrase subunit B,DNA gyrase subunit B,DNA gyrase subunit A, ... | 著者 | Bax, B.D, Chan, P.F, Stavenger, R.A. | 登録日 | 2017-04-17 | 公開日 | 2017-07-12 | 最終更新日 | 2018-10-24 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Thiophene antibacterials that allosterically stabilize DNA-cleavage complexes with DNA gyrase. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4DTN
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![BU of 4dtn by Molmil](/molmil-images/mine/4dtn) | RB69 DNA Polymerase Ternary Complex with dATP Opposite an Abasic Site and ddA/dT as the Penultimate Base-pair | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... | 著者 | Xia, S, Wang, J, Konigsberg, W.H. | 登録日 | 2012-02-21 | 公開日 | 2012-06-06 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
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4DTS
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![BU of 4dts by Molmil](/molmil-images/mine/4dts) | RB69 DNA Polymerase Ternary Complex with dCTP Opposite an Abasic Site and ddC/dG as the Penultimate Base-pair | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... | 著者 | Xia, S, Wang, J, Konigsberg, W.H. | 登録日 | 2012-02-21 | 公開日 | 2012-06-06 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
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4DTU
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![BU of 4dtu by Molmil](/molmil-images/mine/4dtu) | RB69 DNA Polymerase Ternary Complex with dGTP Opposite an Abasic Site and ddC/dG as the Penultimate Base-pair | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... | 著者 | Xia, S, Wang, J, Konigsberg, W.H. | 登録日 | 2012-02-21 | 公開日 | 2012-06-06 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
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4JV1
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![BU of 4jv1 by Molmil](/molmil-images/mine/4jv1) | Ternary complex of gamma-OHPDG adduct modified dna with dna (-1 primer) polymerase iv and incoming dgtp | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*C)-3'), ... | 著者 | Banerjee, S, Shanmugam, G, Stone, M.P. | 登録日 | 2013-03-25 | 公開日 | 2013-08-28 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Ring-Opening of the gamma-OH-PdG Adduct Promotes Error-Free Bypass by the Sulfolobus solfataricus DNA Polymerase Dpo4. Chem.Res.Toxicol., 26, 2013
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3PVX
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![BU of 3pvx by Molmil](/molmil-images/mine/3pvx) | |
4JV0
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![BU of 4jv0 by Molmil](/molmil-images/mine/4jv0) | Ring-Opening of the -OH-PdG Adduct in Ternary Complexes with the Sulfolobus solfataricus DNA polymerase Dpo4 | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*CP*C)-3'), ... | 著者 | Banerjee, S, Shanmugam, G, Stone, M.P. | 登録日 | 2013-03-25 | 公開日 | 2013-08-28 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Ring-Opening of the gamma-OH-PdG Adduct Promotes Error-Free Bypass by the Sulfolobus solfataricus DNA Polymerase Dpo4. Chem.Res.Toxicol., 26, 2013
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6WC2
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![BU of 6wc2 by Molmil](/molmil-images/mine/6wc2) | |
7OTM
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![BU of 7otm by Molmil](/molmil-images/mine/7otm) | Cryo-EM structure of DNA-PKcs in complex with NU7441 | 分子名称: | 8-(dibenzo[b,d]thiophen-4-yl)-2-(morpholin-4-yl)-4H-chromen-4-one, DNA-dependent protein kinase catalytic subunit,DNA-PKcs | 著者 | Liang, S, Thomas, S.E, Blundell, T.L. | 登録日 | 2021-06-10 | 公開日 | 2022-01-12 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | 主引用文献 | Structural insights into inhibitor regulation of the DNA repair protein DNA-PKcs. Nature, 601, 2022
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4JUZ
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![BU of 4juz by Molmil](/molmil-images/mine/4juz) | Ternary complex of gamma-OHPDG adduct modified dna (zero primer) with dna polymerase iv and incoming dgtp | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*CP*C)-3'), ... | 著者 | Banerjee, S, Shanmugam, G, Stone, M.P. | 登録日 | 2013-03-25 | 公開日 | 2013-08-28 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Ring-Opening of the gamma-OH-PdG Adduct Promotes Error-Free Bypass by the Sulfolobus solfataricus DNA Polymerase Dpo4. Chem.Res.Toxicol., 26, 2013
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5NPP
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![BU of 5npp by Molmil](/molmil-images/mine/5npp) | 2.22A STRUCTURE OF THIOPHENE2 AND GSK945237 WITH S.AUREUS DNA GYRASE AND DNA | 分子名称: | (1R)-1-[(4-{[(6,7-dihydro[1,4]dioxino[2,3-c]pyridazin-3-yl)methyl]amino}piperidin-1-yl)methyl]-9-fluoro-1,2-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one, DIMETHYL SULFOXIDE, DNA (5'-D(*AP*GP*CP*CP*GP*TP*AP*GP*GP*TP*AP*CP*CP*TP*AP*CP*GP*GP*CP*T)-3'), ... | 著者 | Bax, B.D, Chan, P.F, Stavenger, R.A. | 登録日 | 2017-04-18 | 公開日 | 2017-07-12 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Thiophene antibacterials that allosterically stabilize DNA-cleavage complexes with DNA gyrase. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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3GQC
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![BU of 3gqc by Molmil](/molmil-images/mine/3gqc) | Structure of human Rev1-DNA-dNTP ternary complex | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*TP*CP*CP*TP*CP*CP*CP*CP*TP*AP*(DOC))-3', 5'-D(*TP*AP*AP*GP*GP*TP*AP*GP*GP*GP*GP*AP*GP*GP*AP*T)-3', ... | 著者 | Swan, M.K, Aggarwal, A.K. | 登録日 | 2009-03-24 | 公開日 | 2009-05-19 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of the human Rev1-DNA-dNTP ternary complex. J.Mol.Biol., 390, 2009
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6WC5
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![BU of 6wc5 by Molmil](/molmil-images/mine/6wc5) | |
3U5Z
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![BU of 3u5z by Molmil](/molmil-images/mine/3u5z) | Structure of T4 Bacteriophage clamp loader bound to the T4 clamp, primer-template DNA, and ATP analog | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA polymerase accessory protein 44, DNA polymerase accessory protein 62, ... | 著者 | Kelch, B.A, Makino, D.L, O'Donnell, M, Kuriyan, J. | 登録日 | 2011-10-11 | 公開日 | 2012-01-04 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | How a DNA polymerase clamp loader opens a sliding clamp. Science, 334, 2011
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4JV2
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![BU of 4jv2 by Molmil](/molmil-images/mine/4jv2) | Ternary complex of gamma-OHPDG adduct modified dna with dna (-1 primer) polymerase iv and incoming datp | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*C)-3'), ... | 著者 | Banerjee, S, Shanmugam, G, Stone, M.P. | 登録日 | 2013-03-25 | 公開日 | 2013-08-28 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | 主引用文献 | Ring-Opening of the gamma-OH-PdG Adduct Promotes Error-Free Bypass by the Sulfolobus solfataricus DNA Polymerase Dpo4. Chem.Res.Toxicol., 26, 2013
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5ED4
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![BU of 5ed4 by Molmil](/molmil-images/mine/5ed4) | Structure of a PhoP-DNA complex | 分子名称: | 1,2-ETHANEDIOL, CACODYLATE ION, CALCIUM ION, ... | 著者 | Wang, S. | 登録日 | 2015-10-20 | 公開日 | 2016-04-27 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis of DNA sequence recognition by the response regulator PhoP in Mycobacterium tuberculosis. Sci Rep, 6, 2016
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6IUC
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![BU of 6iuc by Molmil](/molmil-images/mine/6iuc) | Structure of Helicobacter pylori Soj-ATP complex bound to DNA | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*AP*GP*GP*GP*TP*GP*TP*TP*CP*CP*AP*CP*GP*TP*GP*AP*AP*AP*CP*AP*GP*GP*GP*A)-3'), DNA (5'-D(P*TP*CP*CP*CP*TP*GP*TP*TP*TP*CP*AP*CP*GP*TP*GP*GP*AP*AP*CP*AP*CP*CP*CP*T)-3'), ... | 著者 | Chu, C.H, Yen, C.Y, Sun, Y.J. | 登録日 | 2018-11-28 | 公開日 | 2019-02-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Crystal structures of HpSoj-DNA complexes and the nucleoid-adaptor complex formation in chromosome segregation. Nucleic Acids Res., 47, 2019
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6IUD
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![BU of 6iud by Molmil](/molmil-images/mine/6iud) | Structure of Helicobacter pylori Soj-ADP complex bound to DNA | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(P*AP*GP*GP*GP*TP*GP*TP*TP*CP*CP*AP*CP*GP*TP*GP*AP*AP*AP*CP*AP*GP*GP*GP*A)-3'), DNA (5'-D(P*TP*CP*CP*CP*TP*GP*TP*TP*TP*CP*AP*CP*GP*TP*GP*GP*AP*AP*CP*AP*CP*CP*CP*T)-3'), ... | 著者 | Yen, C.Y, Chu, C.H, Sun, Y.J. | 登録日 | 2018-11-28 | 公開日 | 2019-02-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.506 Å) | 主引用文献 | Crystal structures of HpSoj-DNA complexes and the nucleoid-adaptor complex formation in chromosome segregation. Nucleic Acids Res., 47, 2019
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8TLE
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![BU of 8tle by Molmil](/molmil-images/mine/8tle) | |