PDB: 47120 件ウェブページステータス検索Chemie searchBIRD

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6E2G	Cryo-EM structure of rat TRPV6 in complex with Calmodulin 分子名称: CALCIUM ION, Calmodulin-1, Transient receptor potential cation channel subfamily V member 6 著者 Singh, A.K, McGoldrick, L.L, Sobolevsky, A.I. 登録日 2018-07-11 公開日 2018-08-22 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Mechanism of calmodulin inactivation of the calcium-selective TRP channel TRPV6. Sci Adv, 4, 2018
8UFT	Structure of human endothelial nitric oxide synthase P370N mutant heme domain in complex with 4-methyl-7-(4-methyl-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepin-7-yl)quinolin-2-amine 分子名称: (7M)-4-methyl-7-(4-methyl-2,3,4,5-tetrahydro-1,4-benzoxazepin-7-yl)quinolin-2-amine, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5,6,7,8-TETRAHYDROBIOPTERIN, ... 著者 Li, H, Poulos, T.L. 登録日 2023-10-04 公開日 2024-03-13 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Crystallographic and Computational Insights into Isoform-Selective Dynamics in Nitric Oxide Synthase. Biochemistry, 63, 2024
8UQW	Round 18 Arylesterase Variant of Apo-Phosphotriesterase Measured at 13 keV 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Phosphotriesterase variant PTE-R18 著者 Breeze, C.W, Frkic, R.L, Campbell, E.C, Jackson, C.J. 登録日 2023-10-25 公開日 2024-04-03 最終更新日 2024-04-10 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Mononuclear binding and catalytic activity of europium(III) and gadolinium(III) at the active site of the model metalloenzyme phosphotriesterase. Acta Crystallogr D Struct Biol, 80, 2024
4N3C	Crystal Structure of human O-GlcNAc Transferase bound to a peptide from HCF-1 pro-repeat2(1-26) and UDP-GlcNAc 分子名称: Host cell factor 1, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE 著者 Lazarus, M.B, Herr, W, Walker, S. 登録日 2013-10-06 公開日 2014-01-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 HCF-1 is cleaved in the active site of O-GlcNAc transferase. Science, 342, 2013
6G50	The structure of thiocyanate dehydrogenase from Thioalkalivibrio paradoxus as isolated. 分子名称: 1,2-ETHANEDIOL, COPPER (II) ION, SULFATE ION, ... 著者 Polyakov, K.M, Tsallagov, S.I, Tikhkonova, T.V, Popov, V.O. 登録日 2018-03-28 公開日 2019-04-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Trinuclear copper biocatalytic center forms an active site of thiocyanate dehydrogenase. Proc.Natl.Acad.Sci.USA, 117, 2020
4N4E	Thermolysin in complex with UBTLN58 分子名称: CALCIUM ION, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Krimmer, S.G, Heine, A, Klebe, G. 登録日 2013-10-08 公開日 2014-04-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.13 Å) 主引用文献 Methyl, Ethyl, Propyl, Butyl: Futile But Not for Water, as the Correlation of Structure and Thermodynamic Signature Shows in a Congeneric Series of Thermolysin Inhibitors. Chemmedchem, 4, 2014
8UD3	SARS-CoV-2 Nsp15 bound to poly(A/U) RNA, consensus form 分子名称: Non-structural protein 15, RNA (35-MER) 著者 Ito, F, Yang, H, Zhou, Z.H, Chen, X.S. 登録日 2023-09-28 公開日 2024-04-24 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2.67 Å) 主引用文献 Structural basis for polyuridine tract recognition by SARS-CoV-2 Nsp15. Protein Cell, 15, 2024
8UZW	Selenocysteine synthase- SelA 分子名称: L-seryl-tRNA(Sec) selenium transferase 著者 Balasco Serrao, V.H, Minari, K, Pereira, H.M, Thiemann, O.H. 登録日 2023-11-16 公開日 2024-04-24 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (2.69 Å) 主引用文献 Bacterial selenocysteine synthase structure revealed by single-particle cryoEM. Curr Res Struct Biol, 7, 2024
6G71	Structure of CYP1232A24 from Arthrobacter sp. 分子名称: 1,2-ETHANEDIOL, Cytochrome P450, FE (III) ION, ... 著者 Dubiel, P, Sharma, M, Klenk, J, Hauer, B, Grogan, G. 登録日 2018-04-04 公開日 2019-03-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Identification and characterization of cytochrome P450 1232A24 and 1232F1 from Arthrobacter sp. and their role in the metabolic pathway of papaverine. J.Biochem., 166, 2019
6G19	CryoEM structure of the MDA5-dsRNA filament with 74-degree helical twist 分子名称: Interferon-induced helicase C domain-containing protein 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RNA (5'-R(P*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*AP*G)-3'), ... 著者 Yu, Q, Qu, K, Modis, Y. 登録日 2018-03-20 公開日 2018-11-21 最終更新日 2020-11-18 実験手法 ELECTRON MICROSCOPY (3.68 Å) 主引用文献 Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis. Mol. Cell, 72, 2018
4N5J	Crystal structure of hemagglutinin from an H7N9 influenza virus 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ... 著者 Xu, R, Wilson, I.A. 登録日 2013-10-10 公開日 2013-12-18 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.702 Å) 主引用文献 Preferential recognition of avian-like receptors in human influenza A H7N9 viruses. Science, 342, 2013
6G1Z	Crystal structure of a fluorescence optimized bathy phytochrome PAiRFP2 derived from wild-type Agp2 in its Pfr state. 分子名称: 2-(2-METHOXYETHOXY)ETHANOL, 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3-[(2Z)-2-({3-(2-carboxyethyl)-5-[(E)-(4-ethenyl-3-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl}methylidene)-5-{(Z)-[(3E,4S)-3-ethylidene-4-methyl-5-oxopyrrolidin-2-ylidene]methyl}-4-methyl-2H-pyrrol-3-yl]propanoic acid, ... 著者 Sauthof, L, Schmidt, A, Szczepek, M, Scheerer, P. 登録日 2018-03-22 公開日 2018-11-28 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Structural snapshot of a bacterial phytochrome in its functional intermediate state. Nat Commun, 9, 2018
4K1Y	Crystal structure of Canavalia boliviana lectin in complex with Man1-3Man-OMe 分子名称: CADMIUM ION, CALCIUM ION, Canavalia boliviana lectin, ... 著者 Bezerra, G.A, Viertlmayr, R, Moura, T.R, Delatorre, P, Rocha, B.A.M, Cavada, B.S, Gruber, K. 登録日 2013-04-07 公開日 2014-04-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Studies of an Anti-Inflammatory Lectin from Canavalia boliviana Seeds in Complex with Dimannosides. Plos One, 9, 2014
6G98	Three dimensional structure of human carbonic anhydrase IX in complex with sulfonamide 分子名称: 4-[2-[3-(cyclododecylamino)-2,5,6-tris(fluoranyl)-4-sulfamoyl-phenyl]sulfanylethyl]benzoic acid, Carbonic anhydrase 9, ZINC ION 著者 Leitans, J, Tars, K. 登録日 2018-04-10 公開日 2018-07-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 Novel fluorinated carbonic anhydrase IX inhibitors reduce hypoxia-induced acidification and clonogenic survival of cancer cells. Oncotarget, 9, 2018
8UQZ	Round 18 Arylesterase Variant of Phosphotriesterase Bound to Gadolinium(III) Measured at 9.5 keV 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, GADOLINIUM ION, ... 著者 Breeze, C.W, Frkic, R.L, Campbell, E.C, Jackson, C.J. 登録日 2023-10-25 公開日 2024-04-03 最終更新日 2024-04-10 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Mononuclear binding and catalytic activity of europium(III) and gadolinium(III) at the active site of the model metalloenzyme phosphotriesterase. Acta Crystallogr D Struct Biol, 80, 2024
6G2L	Crystal structure of human mitochondrial 5'(3')-deoxyribonucleotidase in complex with the inhibitor PB-PMTMU 分子名称: 5'(3')-deoxyribonucleotidase, mitochondrial, BETA-MERCAPTOETHANOL, ... 著者 Pachl, P, Rezacova, P, Brynda, J. 登録日 2018-03-23 公開日 2018-07-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Structure-based optimization of bisphosphonate nucleoside inhibitors of human 5'(3')-deoxyribonucleotidases Eur.J.Org.Chem., 2018
8V9I	1-deoxy-D-xylulose 5-phosphate synthase (DXPS) from Deinococcus radiodurans with D-phenylalanine-derived triazole acetylphosphonate (D-PheTrAP) bound 分子名称: 1-deoxy-D-xylulose-5-phosphate synthase, 2-HYDROXY BUTANE-1,4-DIOL, 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-{(1S)-1-[(S)-(2-{1-[(1R)-1-carboxy-2-phenylethyl]-1H-1,2,3-triazol-4-yl}ethoxy)(hydroxy)phosphoryl]-1-hydroxyethyl}-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium, ... 著者 Chen, P.Y.-T, Drennan, C.L. 登録日 2023-12-08 公開日 2024-04-24 実験手法 X-RAY DIFFRACTION (1.981 Å) 主引用文献 Potent Inhibition of E. coli DXP Synthase by a gem -Diaryl Bisubstrate Analog. Acs Infect Dis., 10, 2024
6G9L	Structure of homomeric mLRRC8A volume-regulated anion channel at 5.01 A resolution 分子名称: Volume-regulated anion channel subunit LRRC8A 著者 Sawicka, M, Deneka, D, Lam, A.K.M, Paulino, C, Dutzler, R. 登録日 2018-04-11 公開日 2018-05-16 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (5.01 Å) 主引用文献 Structure of a volume-regulated anion channel of the LRRC8 family. Nature, 558, 2018
8V6K	Apo-state cryo-EM structure of human TRPV3 in cNW30 nanodiscs 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3 著者 Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I. 登録日 2023-12-01 公開日 2024-04-17 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (2.46 Å) 主引用文献 TRPV3 activation by different agonists accompanied by lipid dissociation from the vanilloid site. Sci Adv, 10, 2024
8UFR	Structure of human endothelial nitric oxide synthase heme domain in complex with 4-methyl-7-(4-methyl-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepin-7-yl)quinolin-2-amine dihydrochloride 分子名称: (7M)-4-methyl-7-(4-methyl-2,3,4,5-tetrahydro-1,4-benzoxazepin-7-yl)quinolin-2-amine, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5,6,7,8-TETRAHYDROBIOPTERIN, ... 著者 Li, H, Poulos, T.L. 登録日 2023-10-04 公開日 2024-03-13 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.871 Å) 主引用文献 Crystallographic and Computational Insights into Isoform-Selective Dynamics in Nitric Oxide Synthase. Biochemistry, 63, 2024
6G8W	Crystal Structures of the Single PDZ Domains from GRASP65 and their Interaction with the Golgin GM130 分子名称: 1,2-ETHANEDIOL, Golgi reassembly-stacking protein 1 著者 Jurk, C.M, Roske, Y, Heinemann, U. 登録日 2018-04-10 公開日 2019-04-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Crystal Structures of the Single PDZ Domains from GRASP65 and their Interaction with the Golgin GM130 Croatica Chemica Acta, 2018
6G5R	Structure of the UB2H domain of E.coli PBP1B in complex with LpoB 分子名称: Penicillin-binding protein 1B 著者 Simorre, J.P, Maya Martinez, R.C, Bougault, C. 登録日 2018-03-29 公開日 2019-02-20 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Induced conformational changes activate the peptidoglycan synthase PBP1B. Mol. Microbiol., 110, 2018
4KBM	Structure of the Mtb CarD/RNAP Beta subunit B1-B2 domains complex 分子名称: DNA-directed RNA polymerase subunit beta, RNA polymerase-binding transcription factor CarD 著者 Gulten, G, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) 登録日 2013-04-23 公開日 2013-10-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1146 Å) 主引用文献 Structure of the Mtb CarD/RNAP beta-Lobes Complex Reveals the Molecular Basis of Interaction and Presents a Distinct DNA-Binding Domain for Mtb CarD. Structure, 21, 2013
8V6N	Open-state cryo-EM structure of human TRPV3 in presence of 2-APB in cNW30 nanodiscs 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-aminoethyl diphenylborinate, ARACHIDONIC ACID, ... 著者 Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I. 登録日 2023-12-01 公開日 2024-04-17 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (2.59 Å) 主引用文献 TRPV3 activation by different agonists accompanied by lipid dissociation from the vanilloid site. Sci Adv, 10, 2024
4KMG	Crystal structure of cytochrome c6B from Synechococcus sp. WH8102 分子名称: Cytochrome C6 (Soluble cytochrome F) (Cytochrome c553), HEME C, SODIUM ION 著者 Zatwarnicki, P, Krzywda, S, Barciszewski, J, Jaskolski, M, Szczepaniak, A. 登録日 2013-05-08 公開日 2014-03-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Cytochrome c6B of Synechococcus sp. WH 8102 - Crystal structure and basic properties of novel c6-like family representative. Biochem.Biophys.Res.Commun., 443, 2014

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