8T48
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6FMJ
| pVHL:EloB:EloC in complex with (2S,4R)-1-((S)-2-Acetamidopropanethioyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl) benzyl)pyrrolidine-2-carboxamide (ligand 3) | 分子名称: | (2~{S},4~{R})-1-[(2~{S})-2-acetamidopropanethioyl]-~{N}-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ... | 著者 | Soares, P, Lucas, X, Ciulli, A. | 登録日 | 2018-01-31 | 公開日 | 2018-04-11 | 最終更新日 | 2018-06-20 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Thioamide substitution to probe the hydroxyproline recognition of VHL ligands. Bioorg. Med. Chem., 26, 2018
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4LGX
| Structure of Chitinase D from Serratia proteamaculans revealed an unusually constrained substrate binding site | 分子名称: | ACETATE ION, GLYCEROL, Glycoside hydrolase family 18 | 著者 | Madhuprakash, J, Singh, A, Kumar, S, Sinha, M, Kaur, P, Sharma, S, Podile, A.R, Singh, T.P. | 登録日 | 2013-06-30 | 公開日 | 2013-10-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Inverse relationship between chitobiase and transglycosylation activities of chitinase-D from Serratia proteamaculans revealed by mutational and biophysical analyses. Sci Rep, 5, 2015
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8TUX
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6FWZ
| Crystal structure of human UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) (V264G mutant) in complex with UDP-GlcNAc | 分子名称: | (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, MAGNESIUM ION, UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, ... | 著者 | Pike, A.C.W, Dong, Y.Y, Chu, A, Tessitore, A, Goubin, S, Dong, L, Mukhopadhyay, S, Mahajan, P, Chalk, R, Berridge, G, Wang, D, Kupinska, K, Belaya, K, Beeson, D, Burgess-Brown, N, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2018-03-07 | 公開日 | 2018-07-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structures of DPAGT1 Explain Glycosylation Disease Mechanisms and Advance TB Antibiotic Design. Cell, 175, 2018
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7P6U
| Lon protease from Thermus Thermophilus | 分子名称: | (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK), Lon protease, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Coscia, F, Lowe, J. | 登録日 | 2021-07-18 | 公開日 | 2021-10-27 | 最終更新日 | 2021-11-17 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-EM structure of the full-length Lon protease from Thermus thermophilus. Febs Lett., 595, 2021
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8FRK
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6FX8
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7OLH
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8TJY
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8T2N
| Crystal structure of GABARAP in complex with the LIR of NSs3 | 分子名称: | Gamma-aminobutyric acid receptor-associated protein, Non-structural protein S | 著者 | Ali, M.G.H, Wahba, H.M, Cyr, N, Omichinski, J.G. | 登録日 | 2023-06-06 | 公開日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | An LIR motif in the Rift Valley fever virus NSs protein is critical for the interaction with LC3 family members and inhibition of autophagy. Plos Pathog., 20, 2024
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4LLG
| Crystal Structure Analysis of the E.coli holoenzyme/Gp2 complex | 分子名称: | Bacterial RNA polymerase inhibitor, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Bae, B, Darst, S.A. | 登録日 | 2013-07-09 | 公開日 | 2013-11-13 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.7936 Å) | 主引用文献 | Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1. Proc.Natl.Acad.Sci.USA, 110, 2013
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8FRJ
| Structure of nsp14 N7-MethylTransferase domain fused with TELSAM bound to SGC0946 | 分子名称: | 5-bromo-7-{5-[(3-{[(4-tert-butylphenyl)carbamoyl]amino}propyl)(propan-2-yl)amino]-5-deoxy-beta-D-ribofuranosyl}-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Transcription factor ETV6,Guanine-N7 methyltransferase nsp14 chimera, ZINC ION | 著者 | Kottur, J, Aggarwal, A.K. | 登録日 | 2023-01-07 | 公開日 | 2023-07-26 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Structures of SARS-CoV-2 N7-methyltransferase with DOT1L and PRMT7 inhibitors provide a platform for new antivirals. Plos Pathog., 19, 2023
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8TL6
| Cryo-EM structure of DDB1deltaB-DDA1-DCAF5 | 分子名称: | DDB1- and CUL4-associated factor 5, DET1- and DDB1-associated protein 1, DNA damage-binding protein 1 | 著者 | Yue, H, Hunkeler, M, Roy Burman, S.S, Fischer, E.S. | 登録日 | 2023-07-26 | 公開日 | 2024-04-03 | 最終更新日 | 2024-04-17 | 実験手法 | ELECTRON MICROSCOPY (2.63 Å) | 主引用文献 | Targeting DCAF5 suppresses SMARCB1-mutant cancer by stabilizing SWI/SNF. Nature, 628, 2024
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7OJS
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7OK9
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8TFF
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8FJ4
| LSD1-CoREST in complex with T108, short soaking | 分子名称: | 3-[(1R,2S)-2-(cyclobutylamino)cyclopropyl]-N-phenylbenzamide, Lysine-specific histone demethylase 1A, REST corepressor 1, ... | 著者 | Caroli, J, Mattevi, A. | 登録日 | 2022-12-19 | 公開日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1 to be published
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8FJ7
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8TO2
| Bottom cylinder of high-resolution phycobilisome quenched by OCP (local refinement) | 分子名称: | Allophycocyanin alpha chain, Allophycocyanin beta chain, Allophycocyanin subunit alpha-B, ... | 著者 | Sauer, P.V, Sutter, M, Cupellini, L. | 登録日 | 2023-08-02 | 公開日 | 2024-04-17 | 実験手法 | ELECTRON MICROSCOPY (2 Å) | 主引用文献 | Structural and quantum chemical basis for OCP-mediated quenching of phycobilisomes. Sci Adv, 10, 2024
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4L4E
| Structure of cyanide and camphor bound P450cam mutant L358A/K178G | 分子名称: | CAMPHOR, CYANIDE ION, Camphor 5-monooxygenase, ... | 著者 | Batabyal, D, Li, H, Poulos, T.L. | 登録日 | 2013-06-07 | 公開日 | 2013-07-31 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.261 Å) | 主引用文献 | Synergistic Effects of Mutations in Cytochrome P450cam Designed To Mimic CYP101D1. Biochemistry, 52, 2013
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4LLL
| Crystal structure of S. aureus MepR-DNA complex | 分子名称: | MepR, Palindromized mepR operator sequence | 著者 | Birukou, I, Brennan, R.G. | 登録日 | 2013-07-09 | 公開日 | 2014-05-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.036 Å) | 主引用文献 | Structural mechanism of transcription regulation of the Staphylococcus aureus multidrug efflux operon mepRA by the MarR family repressor MepR. Nucleic Acids Res., 42, 2014
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8TUW
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7OYK
| DNA-binding domain of CggR in complex with the DNA operator | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Central glycolytic genes regulator, ... | 著者 | Novakova, M, Rezacova, P, Skerlova, J, Brynda, J. | 登録日 | 2021-06-24 | 公開日 | 2021-11-10 | 最終更新日 | 2021-11-24 | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | 主引用文献 | Structural insight into DNA recognition by bacterial transcriptional regulators of the SorC/DeoR family. Acta Crystallogr D Struct Biol, 77, 2021
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8TO5
| Central rod disk in C1 symmetry of high-resolution phycobilisome quenched by OCP (local refinement) | 分子名称: | C-phycocyanin alpha subunit, C-phycocyanin beta subunit, PHYCOCYANOBILIN, ... | 著者 | Sauer, P.V, Sutter, M, Cupellini, L. | 登録日 | 2023-08-02 | 公開日 | 2024-04-17 | 実験手法 | ELECTRON MICROSCOPY (1.87 Å) | 主引用文献 | Structural and quantum chemical basis for OCP-mediated quenching of phycobilisomes. Sci Adv, 10, 2024
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