PDB: 5515 件ウェブページステータス検索Chemie searchBIRD

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5UBS	Solution NMR Structure of NERD-S, a natively folded pentamutant of the B1 domain of streptococcal protein G (GB1) with a solvent-exposed Trp43 分子名称: Immunoglobulin G-binding protein G 著者 Damry, A.M, Davey, J.A, Goto, N.K, Chica, R.A. 登録日 2016-12-21 公開日 2017-08-23 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Rational design of proteins that exchange on functional timescales. Nat. Chem. Biol., 13, 2017
5UCF	Solution NMR-derived model of the minor species of DANCER-2, a dynamic and natively folded pentamutant of the B1 domain of streptococcal protein G (GB1) 分子名称: Immunoglobulin G-binding protein G 著者 Damry, A.M, Davey, J.A, Goto, N.K, Chica, R.A. 登録日 2016-12-22 公開日 2017-08-23 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Rational design of proteins that exchange on functional timescales. Nat. Chem. Biol., 13, 2017
5UB0	Solution NMR Structure of NERD-C, a natively folded tetramutant of the B1 domain of streptococcal protein G (GB1) 分子名称: Immunoglobulin G-binding protein G 著者 Damry, A.M, Davey, J.A, Goto, N.K, Chica, R.A. 登録日 2016-12-20 公開日 2017-08-23 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Rational design of proteins that exchange on functional timescales. Nat. Chem. Biol., 13, 2017
5UHR	Crystal structure of (Cit)LANFLV heptapeptide segment from islet amyloid polypeptide (IAPP) incorporated into a macrocyclic beta-sheet template 分子名称: CHLORIDE ION, ORN-CIR-LEU-ALA-ASN-PHE-LEU-VAL-ORN-ILE-LYS-HAO-LYS-A8E 著者 Wang, Y, Kreutzer, A.G, Nowick, J.S. 登録日 2017-01-11 公開日 2017-07-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.798 Å) 主引用文献 A Tetramer Derived from Islet Amyloid Polypeptide. J. Org. Chem., 82, 2017
5UFQ	K-RasG12D(GNP)/R11.1.6 complex 分子名称: CADMIUM ION, CALCIUM ION, CHLORIDE ION, ... 著者 Parker, J.A, Mattos, C. 登録日 2017-01-05 公開日 2017-08-02 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.199 Å) 主引用文献 An engineered protein antagonist of K-Ras/B-Raf interaction. Sci Rep, 7, 2017
4Q5S	Thermus thermophilus RNA polymerase initially transcribing complex containing 6-mer RNA 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*CP*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*GP*CP*AP*GP*CP*CP*A)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3'), ... 著者 Murakami, K.S. 登録日 2014-04-17 公開日 2014-07-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis of transcription initiation by bacterial RNA polymerase holoenzyme. J.Biol.Chem., 289, 2014
5UCE	Solution NMR structure of the major species of DANCER-2, a dynamic and natively folded pentamutant of the B1 domain of streptococcal protein G (GB1) 分子名称: Immunoglobulin G-binding protein G 著者 Damry, A.M, Davey, J.A, Goto, N.K, Chica, R.A. 登録日 2016-12-22 公開日 2017-08-23 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Rational design of proteins that exchange on functional timescales. Nat. Chem. Biol., 13, 2017
5UXT	Coiled-coil Trimer with Glu:Trp:Lys Triad 分子名称: GLYCEROL, coiled-coil trimer with Glu:Trp:Lys triad 著者 Smith, M.S, Billings, W.M, Whitby, F.G, Miller, M.B, Price, J.L. 登録日 2017-02-23 公開日 2017-08-09 実験手法 X-RAY DIFFRACTION (2.197 Å) 主引用文献 Enhancing a long-range salt bridge with intermediate aromatic and nonpolar amino acids. Org. Biomol. Chem., 15, 2017
5V65	Crystal structure of macrocycles containing Abeta 17-23 (LV(PHI)FAED) and Abeta 30-36 (AII(SAR)L(ORN)V) 分子名称: ORN-LEU-VAL-PHI-PHE-ALA-GLU-ASP-ORN-ALA-ILE-ILE-SAR-LEU-MET-VAL 著者 Kreutzer, A.G, Salveson, P.J, Nowick, J.S. 登録日 2017-03-15 公開日 2017-06-28 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 X-ray Crystallographic Structure of a Compact Dodecamer from a Peptide Derived from A beta 16-36. Org. Lett., 19, 2017
5V64	Crystal structure of macrocycles containing Abeta 15-21 (QKLV(PHI)FA) and Abeta 30-36 (AII(SAR)L(ORN)V) 分子名称: CITRATE ANION, ORN-GLN-LYS-LEU-VAL-PHI-PHE-ALA-ORN-ALA-ILE-ILE-SAR-LEU-MET-VAL, SODIUM ION 著者 Salveson, P.J, Spencer, R.K, Nowick, J.S. 登録日 2017-03-15 公開日 2017-06-28 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (2.023 Å) 主引用文献 X-ray Crystallographic Structure of a Compact Dodecamer from a Peptide Derived from A beta 16-36. Org. Lett., 19, 2017
6VC1	Octreotide oxalate 分子名称: OXALATE ION, Octreotide 著者 Spiliopoulou, M, Karavassili, F, Triandafillidis, D, Valmas, A, Kosinas, C, Fili, S, Barlos, K, Barlos, K.K, Morin, M, Reinle-Schmitt, M, Gozzo, F, Margiolaki, I. 登録日 2019-12-20 公開日 2020-12-23 最終更新日 2021-05-19 実験手法 POWDER DIFFRACTION 主引用文献 New perspectives in macromolecular powder diffraction using single-photon-counting strip detectors: high-resolution structure of the pharmaceutical peptide octreotide. Acta Crystallogr.,Sect.A, 77, 2021
6VL5	BG505 SOSIP reconstructed from a designed tetrahedral nanoparticle, BG505 SOSIP-T33_dn2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.v5.2(7S) - gp120, ... 著者 Ward, A.B, Antanasijevic, A. 登録日 2020-01-22 公開日 2020-08-12 最終更新日 2020-09-02 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations. NPJ Vaccines, 5, 2020
4V7Q	Atomic model of an infectious rotavirus particle 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Core scaffold protein, ... 著者 Settembre, E.C, Chen, J.Z, Dormitzer, P.R, Grigorieff, N, Harrison, S.C. 登録日 2010-05-13 公開日 2014-07-09 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Atomic model of an infectious rotavirus particle. Embo J., 30, 2011
4WAC	Crystal Structure of TarM 分子名称: 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Koc, C, Stehle, T, Xia, G, Peschel, A. 登録日 2014-08-29 公開日 2015-02-25 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural and Enzymatic Analysis of TarM Glycosyltransferase from Staphylococcus aureus Reveals an Oligomeric Protein Specific for the Glycosylation of Wall Teichoic Acid. J.Biol.Chem., 290, 2015
4V6I	Localization of the small subunit ribosomal proteins into a 6.1 A cryo-EM map of Saccharomyces cerevisiae translating 80S ribosome 分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein RACK1 (RACK1), ... 著者 Armache, J.-P, Jarasch, A, Anger, A.M, Villa, E, Becker, T, Bhushan, S, Jossinet, F, Habeck, M, Dindar, G, Franckenberg, S, Marquez, V, Mielke, T, Thomm, M, Berninghausen, O, Beatrix, B, Soeding, J, Westhof, E, Wilson, D.N, Beckmann, R. 登録日 2010-10-12 公開日 2014-07-09 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (8.8 Å) 主引用文献 Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution. Proc.Natl.Acad.Sci.USA, 107, 2010
4R1R	RIBONUCLEOTIDE REDUCTASE R1 PROTEIN WITH SUBSTRATE, GDP AND EFFECTOR DTTP FROM ESCHERICHIA COLI 分子名称: GUANOSINE-5'-DIPHOSPHATE, RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN, ... 著者 Eriksson, M, Eklund, H. 登録日 1997-07-22 公開日 1998-01-28 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding. Structure, 5, 1997
4RLM	Hen egg-white lysozyme solved from serial crystallography at a synchrotron source, data processed with CrystFEL 分子名称: Lysozyme C 著者 Botha, S, Nass, K, Barends, T, Kabsch, W, Latz, B, Dworkowski, F, Foucar, L, Panepucci, E, Wang, M, Shoeman, R, Schlichting, I, Doak, R.B. 登録日 2014-10-17 公開日 2015-02-25 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Room-temperature serial crystallography at synchrotron X-ray sources using slowly flowing free-standing high-viscosity microstreams. Acta Crystallogr.,Sect.D, 71, 2015
4TKS	Native-SAD phasing for human EGFR kinase domain. 分子名称: Epidermal growth factor receptor 著者 Cai, Z, Greene, M.I, Liu, Q. 登録日 2014-05-27 公開日 2014-10-08 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.2017 Å) 主引用文献 Multi-crystal native SAD analysis at 6 keV. Acta Crystallogr.,Sect.D, 70, 2014
6PF9	Crystal structure of TS-DHFR from Cryptosporidium hominis in complex with NADPH, FdUMP and 2-(2-(4-((2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl)benzamido)phenyl)acetic acid. 分子名称: 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, Bifunctional dihydrofolate reductase-thymidylate synthase, METHOTREXATE, ... 著者 Czyzyk, D.J, Valhondo, M, Jorgensen, W.L, Anderson, K.S. 登録日 2019-06-21 公開日 2019-10-02 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Structure activity relationship towards design of cryptosporidium specific thymidylate synthase inhibitors. Eur.J.Med.Chem., 183, 2019
6PF8	Crystal structure of TS-DHFR from Cryptosporidium hominis in complex with NADPH, FdUMP and 2-(4-((2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl)benzamido)-4-chlorobenzoic acid 分子名称: 2-({4-[(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]benzene-1-carbonyl}amino)-4-chlorobenzoic acid, 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, Bifunctional dihydrofolate reductase-thymidylate synthase, ... 著者 Czyzyk, D.J, Valhondo, M, Jorgensen, W.L, Anderson, K.S. 登録日 2019-06-21 公開日 2019-10-02 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.533 Å) 主引用文献 Structure activity relationship towards design of cryptosporidium specific thymidylate synthase inhibitors. Eur.J.Med.Chem., 183, 2019
1T2A	Crystal structure of human GDP-D-mannose 4,6-dehydratase 分子名称: GDP-mannose 4,6 dehydratase, GUANOSINE-5'-DIPHOSPHATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Walker, J.R, Vedadi, M, Sharma, S, Houston, S, Wasney, G, Loppnau, P, Sundstrom, M, Arrowsmith, C, Edwards, A, Oppermann, U. 登録日 2004-04-20 公開日 2004-05-10 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Crystal Structure and Biophysical Characterization of Human GDP-D-mannose 4,6-dehydratase To be Published
6PF6	Crystal structure of TS-DHFR from Cryptosporidium hominis in complex with NADPH, FdUMP and 2-(4-((2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl)benzamido)terephthalic acid 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2-({4-[(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]benzene-1-carbonyl}amino)benzene-1,4-dicarboxylic acid, Thymidylate synthase,Thymidylate synthase 著者 Czyzyk, D.L, Valhondo, M, Jorgensen, W.L, Anderson, K.S. 登録日 2019-06-21 公開日 2019-10-16 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.502 Å) 主引用文献 Structure activity relationship towards design of cryptosporidium specific thymidylate synthase inhibitors. Eur.J.Med.Chem., 183, 2019
6PFG	Crystal structure of TS-DHFR from Cryptosporidium hominis in complex with NADPH, FdUMP and 2-(4-((2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl)benzamido)-4-carbamoylbenzoic acid. 分子名称: 2-({4-[(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]benzene-1-carbonyl}amino)-4-carbamoylbenzoic acid, 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, Bifunctional dihydrofolate reductase-thymidylate synthase, ... 著者 Czyzyk, D.J, Valhondo, M, Jorgensen, W.L, Anderson, K.S. 登録日 2019-06-21 公開日 2019-10-02 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.706 Å) 主引用文献 Structure activity relationship towards design of cryptosporidium specific thymidylate synthase inhibitors. Eur.J.Med.Chem., 183, 2019
1TCU	Crystal Structure of the Purine Nucleoside Phosphorylase from Schistosoma mansoni in complex with phosphate and acetate 分子名称: ACETATE ION, DIMETHYL SULFOXIDE, PHOSPHATE ION, ... 著者 Pereira, H.D, Franco, G.R, Cleasby, A, Garratt, R.C. 登録日 2004-05-21 公開日 2005-05-24 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structures for the Potential Drug Target Purine Nucleoside Phosphorylase from Schistosoma mansoni Causal Agent of Schistosomiasis. J.Mol.Biol., 353, 2005
6PB6	The E. coli class-II CAP-dependent transcription activation complex at the state 2 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Liu, B, Shi, W. 登録日 2019-06-13 公開日 2020-03-18 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.29 Å) 主引用文献 Visualization of two architectures in class-II CAP-dependent transcription activation Plos Biol., 18, 2020

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