PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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4MXT	Crystal structure of an Outer-membrane lipoprotein carrier protein (BACUNI_04723) from Bacteroides uniformis ATCC 8492 at 1.40 A resolution 分子名称: DI(HYDROXYETHYL)ETHER, Uncharacterized protein 著者 Joint Center for Structural Genomics (JCSG) 登録日 2013-09-26 公開日 2013-10-16 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of a hypothetical protein (BACUNI_04723) from Bacteroides uniformis ATCC 8492 at 1.40 A resolution To be published
4QJX	Crystal structure of human carbonic anhydrase isozyme XIII with inhibitor 分子名称: 1,2-ETHANEDIOL, 3-(benzylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide, Carbonic anhydrase 13, ... 著者 Smirnov, A, Manakova, E, Grazulis, S. 登録日 2014-06-05 公開日 2015-04-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Functionalization of Fluorinated Benzenesulfonamides and Their Inhibitory Properties toward Carbonic Anhydrases Chemmedchem, 10, 2015
3WZJ	CRYSTAL STRUCTURE OF HUMAN MPS1 CATALYTIC DOMAIN IN COMPLEX WITH 4-(6-(cyclohexylamino)-8-(((tetrahydro-2H-pyran-4-yl)methyl)amino)imidazo[1,2-b]pyridazin-3-yl)-N-cyclopropylbenzamide 分子名称: 4-{6-(cyclohexylamino)-8-[(tetrahydro-2H-pyran-4-ylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}-N-cyclopropylbenzamide, Dual specificity protein kinase TTK 著者 Kusakabe, K, Ide, N, Daigo, Y, Itoh, T, Yamamoto, T, Kojima, E, Mitsuoka, Y, Tadano, G, Tagashira, S, Higashino, K, Okano, Y, Sato, Y, Inoue, M, Iguchi, M, Kanazawa, T, Ishioka, Y, Dohi, K, Kido, Y, Sakamoto, S, Ando, S, Maeda, M, Higaki, M, Yoshizawa, H, Mura, H, Nakamura, Y. 登録日 2014-09-29 公開日 2015-02-11 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity. J.Med.Chem., 58, 2015
3WZV	3-isopropylmalate dehydrogenase from Shewanella oneidensis MR-1 at 0.1MPa - complex with IPM and Mg 分子名称: 3-ISOPROPYLMALIC ACID, 3-isopropylmalate dehydrogenase, MAGNESIUM ION 著者 Nagae, T, Watanabe, N. 登録日 2014-10-07 公開日 2015-10-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Pressure Adaptation of 3-Isopropylmalate Dehydrogenase from the Extremely Piezophilic Bacterium Shewanella benthica is Attributed to just One Amino Acid Substitution To be Published
4EMV	Crystal structure of a topoisomerase ATP inhibitor 分子名称: 5-{2-(ethylcarbamoyl)-4-[3-(trifluoromethyl)-1H-pyrazol-1-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl}pyridine-3-carboxylic acid, DNA topoisomerase IV, B subunit 著者 Boriack-Sjodin, P.A, Manchester, J, Hull, K. 登録日 2012-04-12 公開日 2012-08-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Discovery of a novel azaindole class of antibacterial agents targeting the ATPase domains of DNA gyrase and Topoisomerase IV. Bioorg.Med.Chem.Lett., 22, 2012
4QJO	Crystal structure of catalytic domain of human carbonic anhydrase isozyme XII with inhibitor 分子名称: 1,2-ETHANEDIOL, 3-(benzylamino)-2,5,6-trifluoro-4-[(2-phenylethyl)sulfonyl]benzenesulfonamide, Carbonic anhydrase 12, ... 著者 Smirnov, A, Manakova, E, Grazulis, S. 登録日 2014-06-04 公開日 2015-04-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Functionalization of Fluorinated Benzenesulfonamides and Their Inhibitory Properties toward Carbonic Anhydrases Chemmedchem, 10, 2015
4QOK	Structural basis for ineffective T-cell responses to MHC anchor residue improved heteroclitic peptides 分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... 著者 Rizkallah, P.J, Cole, D.K, Madura, F, Sewell, A.K. 登録日 2014-06-20 公開日 2014-12-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis for ineffective T-cell responses to MHC anchor residue-improved "heteroclitic" peptides. Eur.J.Immunol., 45, 2015
4PYT	Crystal structure of a MurB family EP-UDP-N-acetylglucosamine reductase 分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, ... 著者 Cao, H, Franz, L, Sen, S, Bingman, C.A, Auldridge, M, Steinmetz, E, Mead, D, Phillips Jr, G.N. 登録日 2014-03-27 公開日 2014-05-21 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.853 Å) 主引用文献 LucY: A Versatile New Fluorescent Reporter Protein. Plos One, 10, 2015
4PYY	Crystal structure of human carbonic anhydrase isozyme II with inhibitor 分子名称: 3-(cyclooctylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide, Carbonic anhydrase 2, ZINC ION 著者 Smirnov, A, Manakova, E, Grazulis, S. 登録日 2014-03-28 公開日 2015-01-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Discovery and characterization of novel selective inhibitors of carbonic anhydrase IX. J.Med.Chem., 57, 2014
4E43	HIV protease (PR) dimer with acetate in exo site and peptide in active site 分子名称: ACETATE ION, BETA-MERCAPTOETHANOL, DIMETHYL SULFOXIDE, ... 著者 Stout, C.D. 登録日 2012-03-11 公開日 2012-05-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Fragment-based screen against HIV protease. Chem.Biol.Drug Des., 75, 2010
4Q04	Crystal structure of URE3-BP from Entomaeba histolytica without calcium 分子名称: GLYCEROL, MAGNESIUM ION, SODIUM ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2014-03-31 公開日 2014-04-23 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of URE3-BP from Entomaeba histolytica TO BE PUBLISHED
4KE7	Crystal structure of Monoglyceride lipase from Bacillus sp. H257 in complex with an 1-myristoyl glycerol analogue 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Thermostable monoacylglycerol lipase, dodecyl hydrogen (S)-(3-azidopropyl)phosphonate 著者 Rengachari, S, Aschauer, P, Gruber, K, Dreveny, I, Oberer, M. 登録日 2013-04-25 公開日 2013-09-18 最終更新日 2013-11-20 実験手法 X-RAY DIFFRACTION (1.699 Å) 主引用文献 Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase. J.Biol.Chem., 288, 2013
4EBQ	Fab structure of anti-Vaccinia virus D8L antigen mouse IgG2a LA5 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... 著者 Matho, M.H, Zajonc, D.M. 登録日 2012-03-23 公開日 2012-06-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural and Biochemical Characterization of the Vaccinia Virus Envelope Protein D8 and Its Recognition by the Antibody LA5. J.Virol., 86, 2012
4RUV	Crystal structure of thioredoxin 2 from Staphylococcus aureus NCTC8325 分子名称: Thioredoxin 著者 Bose, M, Biswas, R, Roychowdhury, A, Bhattacharyya, S, Ghosh, A.K, Das, A.K. 登録日 2014-11-22 公開日 2015-12-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Elucidation of the mechanism of disulfide exchange between staphylococcal thioredoxin2 and thioredoxin reductase2: A structural insight. Biochimie, 160, 2019
3WZX	S266A mutant 3-isopropylmalate dehydrogenase from Shewanella oneidensis MR-1 at 0.1MPa - complex with IPM and Mg 分子名称: 3-ISOPROPYLMALIC ACID, 3-isopropylmalate dehydrogenase, MAGNESIUM ION 著者 Nagae, T, Watanabe, N. 登録日 2014-10-08 公開日 2015-10-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Pressure Adaptation of 3-Isopropylmalate Dehydrogenase from the Extremely Piezophilic Bacterium Shewanella benthica is Attributed to just One Amino Acid Substitution To be Published
4EF1	Crystal structure of a pheromone cOB1 precursor/lipoprotein, YaeC family (EF2496) from Enterococcus faecalis V583 at 1.90 A resolution 分子名称: Pheromone cOB1/lipoprotein, YaeC family, SELENOMETHIONINE 著者 Joint Center for Structural Genomics (JCSG) 登録日 2012-03-28 公開日 2012-04-25 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of a pheromone cOB1 precursor/lipoprotein, YaeC family (EF2496) from Enterococcus faecalis V583 at 1.90 A resolution To be published
4S1O	Structure of Mycobacterium tuberculosis NadD in complex with NADP 分子名称: CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Probable nicotinate-nucleotide adenylyltransferase 著者 Korotkov, K.V. 登録日 2015-01-14 公開日 2016-01-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Structure of Mycobacterium tuberculosis protein To be Published
4EJD	HIV Protease (PR) dimer in closed form with pepstatin in active site and fragment 1F1 in the outside/top of flap 分子名称: 1H-indole-6-carboxylic acid, BETA-MERCAPTOETHANOL, GLYCEROL, ... 著者 Tiefenbrunn, T, Stout, C.D. 登録日 2012-04-06 公開日 2013-05-01 最終更新日 2014-02-19 実験手法 X-RAY DIFFRACTION (1.103 Å) 主引用文献 Small molecule regulation of protein conformation by binding in the Flap of HIV protease. Acs Chem.Biol., 8, 2013
3R4H	Crystal structure of the 4-helix coiled coil CC-Tet-phi22 分子名称: coiled coil helix CC-Tet-phi22 著者 Zaccai, N.R, Chi, B.H.C, Woolfson, D.N, Brady, R.L. 登録日 2011-03-17 公開日 2011-11-16 最終更新日 2019-07-17 実験手法 X-RAY DIFFRACTION (2.7003 Å) 主引用文献 A de novo peptide hexamer with a mutable channel. Nat.Chem.Biol., 7, 2011
3R4R	Crystal structure of a fimbrial assembly protein (BDI_3522) from Parabacteroides distasonis ATCC 8503 at 2.38 A resolution 分子名称: 1,2-ETHANEDIOL, SULFATE ION, hypothetical fimbrial assembly protein 著者 Joint Center for Structural Genomics (JCSG) 登録日 2011-03-17 公開日 2011-03-30 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 A Distinct Type of Pilus from the Human Microbiome. Cell, 165, 2016
4KKX	Crystal structure of Tryptophan Synthase from Salmonella typhimurium with 2-aminophenol quinonoid in the beta site and the F6 inhibitor in the alpha site 分子名称: 1,2-ETHANEDIOL, 2-{[4-(TRIFLUOROMETHOXY)BENZOYL]AMINO}ETHYL DIHYDROGEN PHOSPHATE, DI(HYDROXYETHYL)ETHER, ... 著者 Hilario, E, Niks, D, Dunn, M.F, Mueller, L.J, Fan, L. 登録日 2013-05-06 公開日 2014-01-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Allostery and substrate channeling in the tryptophan synthase bienzyme complex: evidence for two subunit conformations and four quaternary states. Biochemistry, 52, 2013
4RQY	RE-REFINED STRUCTURE OF 1TE0 - STRUCTURAL ANALYSIS of DEGS, A STRESS SENSOR OF THE BACTERIAL PERIPLASM 分子名称: PHOSPHATE ION, Protease degS 著者 Sauer, R.T, Grant, R.A. 登録日 2014-11-05 公開日 2015-03-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.204 Å) 主引用文献 A Conserved Activation Cluster Is Required for Allosteric Communication in HtrA-Family Proteases. Structure, 23, 2015
4ROF	Crystal Structure of WW3 domain of ITCH in complex with TXNIP peptide 分子名称: E3 ubiquitin-protein ligase Itchy homolog, Thioredoxin-interacting protein 著者 Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2014-10-28 公開日 2014-12-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Crystal Structure of WW3 domain of ITCH in complex with TXNIP peptide To be Published
4NOT	Crystal structure of Dioclea sclerocarpa lectin complexed with X-man 分子名称: 5-bromo-4-chloro-1H-indol-3-yl alpha-D-mannopyranoside, CALCIUM ION, Lectin alpha chain, ... 著者 Barroso-Neto, I.L, Teixeira, C.S, Correia, J.L.A, Santiago, M.Q, Pinto-Junior, V.R, Osterne, V.J.S, Plinio, D, Rocha, B.A.M, Cavada, B.S. 登録日 2013-11-20 公開日 2015-01-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal structure of Dioclea sclerocarpa lectin complexed with X-man To be Published
4RO9	2.0A resolution structure of SRPN2 (S358E) from Anopheles gambiae 分子名称: GLYCEROL, Serpin 2 著者 Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K. 登録日 2014-10-28 公開日 2014-12-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and Inhibitory Effects of Hinge Loop Mutagenesis in Serpin-2 from the Malaria Vector Anopheles gambiae. J.Biol.Chem., 290, 2015

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