4QJX

Crystal structure of human carbonic anhydrase isozyme XIII with inhibitor

Summary for 4QJX

Entry DOI	10.2210/pdb4qjx/pdb
Related	4QIY 4QIZ 4QJ0 4QJM 4QJO 4QJP 4QJW 4QTL
Descriptor	Carbonic anhydrase 13, ZINC ION, DI(HYDROXYETHYL)ETHER, ... (6 entities in total)
Functional Keywords	drug design, carbonic anhydrase, benzenesulfonamide, metal-binding, lyase-lyase inhibitor complex, lyase/lyase inhibitor
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	30271.33
Authors	Smirnov, A.,Manakova, E.,Grazulis, S. (deposition date: 2014-06-05, release date: 2015-04-15, Last modification date: 2023-11-08)
Primary citation	Dudutiene, V.,Zubriene, A.,Smirnov, A.,Timm, D.D.,Smirnoviene, J.,Kazokaite, J.,Michailoviene, V.,Zaksauskas, A.,Manakova, E.,Grazulis, S.,Matulis, D. Functionalization of Fluorinated Benzenesulfonamides and Their Inhibitory Properties toward Carbonic Anhydrases Chemmedchem, 10:662-687, 2015 Cited by PubMed: 25758852 DOI: 10.1002/cmdc.201402490 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation