PDB: 243083 件ウェブページステータス検索Chemie searchBIRD

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1WZF	Crystal Structure Of An Artificial Metalloprotein: Fe(10-COOH-Salophen)/Wild Type Heme oxygenase 分子名称: GLYCEROL, Heme oxygenase, SULFATE ION, ... 著者 Unno, M, Yokoi, N, Ueno, T, Watanabe, Y, Ikeda-Saito, M. 登録日 2005-03-04 公開日 2006-02-21 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Design of metal cofactors activated by a protein-protein electron transfer system. Proc.Natl.Acad.Sci.Usa, 103, 2006
3NSE	BOVINE ENOS, H4B-FREE, SEITU COMPLEX 分子名称: ACETATE ION, ARGININE, CACODYLATE ION, ... 著者 Raman, C.S, Li, H, Martasek, P, Kral, V, Masters, B.S.S, Poulos, T.L. 登録日 1998-09-23 公開日 1999-05-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of constitutive endothelial nitric oxide synthase: a paradigm for pterin function involving a novel metal center. Cell(Cambridge,Mass.), 95, 1998
3W7A	Crystal Structure of azoreductase AzrC fin complex with sulfone-modified azo dye Acid Red 88 分子名称: 4-[(E)-(2-hydroxynaphthalen-1-yl)diazenyl]naphthalene-1-sulfonic acid, CALCIUM ION, FLAVIN MONONUCLEOTIDE, ... 著者 Yu, J, Ogata, D, Ooi, T, Yao, M. 登録日 2013-02-27 公開日 2014-02-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structures of AzrA and of AzrC complexed with substrate or inhibitor: insight into substrate specificity and catalytic mechanism. Acta Crystallogr.,Sect.D, 70, 2014
1P3T	Crystal Structures of the NO-and CO-Bound Heme Oxygenase From Neisseria Meningitidis: Implications for Oxygen Activation 分子名称: Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE 著者 Friedman, J, Lad, L, Deshmukh, R, Li, H, Wilks, A, Poulos, T.L. 登録日 2003-04-18 公開日 2003-12-09 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of the NO- and CO-bound heme oxygenase from Neisseriae meningitidis. Implications for O2 activation J.Biol.Chem., 278, 2003
1P3V	Crystal Structures of the NO-and CO-Bound Heme Oxygenase From Neisseria Meningitidis: Implications for Oxygen Activation 分子名称: CARBON MONOXIDE, Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE 著者 Friedman, J, Lad, L, Deshmukh, R, Li, H, Wilks, A, Poulos, T.L. 登録日 2003-04-18 公開日 2003-12-09 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal structures of the NO- and CO-bound heme oxygenase from Neisseriae meningitidis. Implications for O2 activation J.Biol.Chem., 278, 2003
3O73	Crystal structure of quinone reductase 2 in complex with the indolequinone MAC627 分子名称: 5-[(4-aminobutyl)amino]-1,2-dimethyl-3-[(4-nitrophenoxy)methyl]-1H-indole-4,7-dione, FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ... 著者 Dufour, M, Yan, C, Colucci, M.A, Siegel, D, Li, Y, De Matteis, C.I, Ross, D, Moody, C.J. 登録日 2010-07-30 公開日 2011-05-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Mechanism-Based Inhibition of Quinone Reductase 2 (NQO2): Selectivity for NQO2 over NQO1 and Structural Basis for Flavoprotein Inhibition. Chembiochem, 12, 2011
1FWX	CRYSTAL STRUCTURE OF NITROUS OXIDE REDUCTASE FROM P. DENITRIFICANS 分子名称: (MU-4-SULFIDO)-TETRA-NUCLEAR COPPER ION, CALCIUM ION, CHLORIDE ION, ... 著者 Brown, K, Djinovic-Carugo, K, Haltia, T, Cabrito, I, Saraste, M, Moura, J.J, Moura, I, Tegoni, M, Cambillau, C. 登録日 2000-09-25 公開日 2001-09-25 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Revisiting the Catalytic CuZ Cluster of Nitrous Oxide (N2O) Reductase. Evidence of a Bridging Inorganic Sulfur J.Biol.Chem., 275, 2000
3DHI	Crystal Structure of Reduced Toluene 4-Monoxygenase Hydroxylase Complexed with Effector Protein 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, FE (III) ION, ... 著者 Bailey, L.J, Mccoy, J.G, Phillips Jr, G.N, Fox, B.G. 登録日 2008-06-17 公開日 2008-12-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Structural consequences of effector protein complex formation in a diiron hydroxylase. Proc.Natl.Acad.Sci.USA, 105, 2008
3W8X	The complex structure of EncM with trifluorotriketide 分子名称: 6,6,6-trifluoro-1-phenylhexane-1,3,5-trione, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... 著者 Teufel, R, Miyanaga, A, Stull, F, Michaudel, Q, Louie, G, Noel, J.P, Baran, P.S, Palfey, B, Moore, B.S. 登録日 2013-03-22 公開日 2013-10-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement. Nature, 503, 2013
1N62	Crystal Structure of the Mo,Cu-CO Dehydrogenase (CODH), n-butylisocyanide-bound state 分子名称: CU(I)-S-MO(IV)(=O)O-NBIC CLUSTER, Carbon monoxide dehydrogenase large chain, Carbon monoxide dehydrogenase medium chain, ... 著者 Dobbek, H, Gremer, L, Kiefersauer, R, Huber, R, Meyer, O. 登録日 2002-11-08 公開日 2002-12-18 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.09 Å) 主引用文献 Catalysis at a dinuclear [CuSMo(=O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution Proc.Natl.Acad.Sci.USA, 99, 2002
6KLJ	Crystal Structure of the Zea Mays laccase 3 complexed with coniferyl 分子名称: (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enal, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Xie, T, Liu, Z.C, Wang, G.G. 登録日 2019-07-30 公開日 2020-01-01 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.998 Å) 主引用文献 Structural basis for monolignol oxidation by a maize laccase. Nat.Plants, 6, 2020
1BGJ	P-HYDROXYBENZOATE HYDROXYLASE (PHBH) MUTANT WITH CYS 116 REPLACED BY SER (C116S) AND HIS 162 REPLACED BY ARG (H162R), IN COMPLEX WITH FAD AND 4-HYDROXYBENZOIC ACID 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE, P-HYDROXYBENZOIC ACID 著者 Eppink, M.H.M, Schreuder, H.A, Van Berkel, W.J.H. 登録日 1998-05-29 公開日 1998-08-12 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Interdomain binding of NADPH in p-hydroxybenzoate hydroxylase as suggested by kinetic, crystallographic and modeling studies of histidine 162 and arginine 269 variants. J.Biol.Chem., 273, 1998
5UFG	Crystal Structure of CYP2B6 (Y226H/K262R/I114V) in complex with myrtenyl bromide 分子名称: (1S,5R)-2-(bromomethyl)-6,6-dimethylbicyclo[3.1.1]hept-2-ene, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B6, ... 著者 Shah, M.B, Halpert, J.R. 登録日 2017-01-04 公開日 2017-04-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Halogen-pi Interactions in the Cytochrome P450 Active Site: Structural Insights into Human CYP2B6 Substrate Selectivity. ACS Chem. Biol., 12, 2017
1WZG	Crystal Structure Of An Artificial Metalloprotein: Fe(Salophen)/Wild Type Heme oxygenase 分子名称: 2,2'-[1,2-PHENYLENEBIS(NITRILOMETHYLIDYNE)]BIS[PHENOLATO]](2-)-N,N',O,O']-IRON, GLYCEROL, Heme oxygenase, ... 著者 Unno, M, Yokoi, N, Ueno, T, Watanabe, Y, Ikeda-Saito, M. 登録日 2005-03-04 公開日 2006-02-21 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Design of metal cofactors activated by a protein-protein electron transfer system. Proc.Natl.Acad.Sci.Usa, 103, 2006
1GVG	Crystal Structure of Clavaminate Synthase with Nitric Oxide 分子名称: 2-OXOGLUTARIC ACID, CLAVAMINATE SYNTHASE 1, DEOXYGUANIDINOPROCLAVAMINIC ACID, ... 著者 Zhang, Z.H, Ren, J, McKinnon, C.H, Clifton, I.J, Harlos, K, Schofield, C.J. 登録日 2002-02-12 公開日 2003-02-07 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Crystal Structure of a Clavaminate Synthase-Fe(II) -2-Oxoglutarate-Substrate-No Complex: Evidence for Metal Centered Rearrangements FEBS Lett., 517, 2002
2HX2	Bovine eNOS heme domain complexed with (4S)-N-{4-Amino-5-[(2-aminoethyl)-hydroxyamino]-pentyl}-N'-nitroguanidine 分子名称: (4S)-N-{4-AMINO-5-[(2-AMINOETHYL)(HYDROXYAMINO]-PENTYL}-N'-NITROGUANIDINE, 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ... 著者 Igarashi, J, Li, H, Poulos, T.L. 登録日 2006-08-02 公開日 2007-04-24 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure-Based Design and Synthesis of N(omega)-Nitro-l-Arginine-Containing Peptidomimetics as Selective Inhibitors of Neuronal Nitric Oxide Synthase. Displacement of the Heme Structural Water. J.Med.Chem., 50, 2007
5TQN	Lipoxygenase-1 (soybean) L546A mutant at 293K 分子名称: FE (II) ION, Seed linoleate 13S-lipoxygenase-1 著者 Poss, E.M, Fraser, J.S, Gee, C. 登録日 2016-10-24 公開日 2017-11-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Biophysical Characterization of a Disabled Double Mutant of Soybean Lipoxygenase: The "Undoing" of Precise Substrate Positioning Relative to Metal Cofactor and an Identified Dynamical Network. J.Am.Chem.Soc., 141, 2019
6I0D	Respiratory complex I from Thermus thermophilus with bound Decyl-Ubiquinone 分子名称: 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... 著者 Gutierrez-Fernandez, J, Minhas, G.S, Sazanov, L.A. 登録日 2018-10-25 公開日 2020-09-02 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Key role of quinone in the mechanism of respiratory complex I. Nat Commun, 11, 2020
2IG9	Structure of a full-length Homoprotocatechuate 2,3-Dioxygenase from B. fuscum in a new spacegroup. 分子名称: CALCIUM ION, CHLORIDE ION, FE (II) ION, ... 著者 Kovaleva, E.G, Lipscomb, J.D. 登録日 2006-09-22 公開日 2007-04-24 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structures of Fe2+ dioxygenase superoxo, alkylperoxo, and bound product intermediates Science, 316, 2007
1LPM	A STRUCTURAL BASIS FOR THE CHIRAL PREFERENCES OF LIPASES 分子名称: (1R)-MENTHYL HEXYL PHOSPHONATE GROUP, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Grochulski, P.G, Cygler, M.C. 登録日 1995-01-06 公開日 1995-04-20 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 A Structural Basis for the Chiral Preferences of Lipases J.Am.Chem.Soc., 116, 1994
4CVG	Structure of bovine endothelial nitric oxide synthase heme domain (H4B-free) supplemented with 50uM Zn acetate and with poor binding of 6-acetyl-2-amino-7,7-dimethyl-7,8-dihydropteridin-4(3H)-one. 分子名称: ACETATE ION, ARGININE, GLYCEROL, ... 著者 Chreifi, G, Li, H, Poulos, T.L. 登録日 2014-03-25 公開日 2014-05-28 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Communication between the Zinc and Tetrahydrobiopterin Binding Sites in Nitric Oxide Synthase. Biochemistry, 53, 2014
4CX1	Structure of bovine endothelial nitric oxide synthase L111A mutant heme domain in complex with 4-METHYL-6-(((3R,4R)-4-((5-(4- METHYLPYRIDIN-2-YL)PENTYL)OXY)PYRROLIDIN-3-YL)METHYL)PYRIDIN-2-AMINE 分子名称: 2-AMINO-6-(1,2-DIHYDROXY-PROPYL)-7,8-DIHYDRO-6H-PTERIDIN-4-ONE, 4-methyl-6-{[(3R,4R)-4-{[5-(4-methylpyridin-2-yl)pentyl]oxy}pyrrolidin-3-yl]methyl}pyridin-2-amine, ACETATE ION, ... 著者 Li, H, Poulos, T.L. 登録日 2014-04-03 公開日 2014-08-13 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Mobility of a Conserved Tyrosine Residue Controls Isoform-Dependent Enzyme-Inhibitor Interactions in Nitric Oxide Synthases. Biochemistry, 53, 2014
4CX2	Structure of bovine endothelial nitric oxide synthase heme domain in complex with 6-(5-(((3R,4R)-4-((6-AMINO-4-METHYLPYRIDIN-2-YL)METHYL) PYRROLIDIN-3-YL)OXY)PENTYL)-4-METHYLPYRIDIN-2-AMINE 分子名称: 2-AMINO-6-(1,2-DIHYDROXY-PROPYL)-7,8-DIHYDRO-6H-PTERIDIN-4-ONE, 6-[5-({(3R,4R)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}oxy)pentyl]-4-methylpyridin-2-amine, ACETATE ION, ... 著者 Li, H, Poulos, T.L. 登録日 2014-04-03 公開日 2014-08-13 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Mobility of a Conserved Tyrosine Residue Controls Isoform-Dependent Enzyme-Inhibitor Interactions in Nitric Oxide Synthases. Biochemistry, 53, 2014
1YJK	Reduced Peptidylglycine Alpha-Hydroxylating Monooxygenase (PHM) in a New Crystal Form 分子名称: COPPER (II) ION, GLYCEROL, Peptidyl-glycine alpha-amidating monooxygenase 著者 Siebert, X, Eipper, B.A, Mains, R.E, Prigge, S.T, Blackburn, N.J, Amzel, L.M. 登録日 2005-01-14 公開日 2005-11-15 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The Catalytic Copper of Peptidylglycine alpha-Hydroxylating Monooxygenase also Plays a Critical Structural Role. Biophys.J., 89, 2005
3NLT	Structure of endothelial nitric oxide synthase heme domain complexed with N1-{(3'S,4'S)-4'-[(6"-amino-4"-methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}- N2-(3'-fluorophenethyl)ethane-1,2-diamine tetrahydrochloride 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 6-({(3S,4S)-4-[2-({2,2-difluoro-2-[(2R)-piperidin-2-yl]ethyl}amino)ethoxy]pyrrolidin-3-yl}methyl)-4-methylpyridin-2-amine, CACODYLIC ACID, ... 著者 Xue, F, Li, H, Fang, J, Delker, S.L, Poulos, T.L, Silverman, R.B. 登録日 2010-06-21 公開日 2011-01-19 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.74 Å) 主引用文献 Potent, highly selective, and orally bioavailable gem-difluorinated monocationic inhibitors of neuronal nitric oxide synthase. J.Am.Chem.Soc., 132, 2010

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