5UFG

Crystal Structure of CYP2B6 (Y226H/K262R/I114V) in complex with myrtenyl bromide

Summary for 5UFG

Entry DOI	10.2210/pdb5ufg/pdb
Related	3IBD 4I91 5UAP 5UDA 5UEC
Descriptor	Cytochrome P450 2B6, PROTOPORPHYRIN IX CONTAINING FE, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, ... (5 entities in total)
Functional Keywords	oxidoreductase, cytochrome p450 2b6
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	56947.32
Authors	Shah, M.B.,Halpert, J.R. (deposition date: 2017-01-04, release date: 2017-04-12, Last modification date: 2023-10-04)
Primary citation	Shah, M.B.,Liu, J.,Zhang, Q.,Stout, C.D.,Halpert, J.R. Halogen-pi Interactions in the Cytochrome P450 Active Site: Structural Insights into Human CYP2B6 Substrate Selectivity. ACS Chem. Biol., 12:1204-1210, 2017 Cited by PubMed: 28368100 DOI: 10.1021/acschembio.7b00056 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.76 Å)

Structure validation